Hanne Mørck Nielsen

Hanne Mørck Nielsen

Professor

ORCID: 0000-0002-7285-9100

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  1. Published

    Monosized Polymeric Microspheres Designed for Passive Lung Targeting: Biodistribution and Pharmacokinetics after Intravenous Administration

    Agnoletti, M., Rodríguez-Rodríguez, C., Klodzinska, S. N., Esposito, T., Saatchi, K., Nielsen, Hanne Mørck & Häfeli, U. O., 2020, In: ACS Nano. 14, p. 6693-6706

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Peptide-Membrane Interactions Monitored by Fluorescence Lifetime Imaging: A Study Case of Transportan 10

    Anselmo, S., Sancataldo, G., Nielsen, Hanne Mørck, Foderà, Vito & Vetri, V., 2021, In: Langmuir. 37, 44, p. 13148-13159

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Models to predict intestinal absorption of therapeutic peptides and proteins

    Antunes, F., Andrade, F., Ferreira, D., Nielsen, Hanne Mørck & Sarmento, B., Jan 2013, In: Current Drug Metabolism. 14, 1, p. 4-20 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Cell-Penetrating Peptides as Tools to Facilitate Oral Delivery of Biopharmaceuticals

    Asgreen, Camilla Jantzen, Fredholt, Freja, Nielsen, Hanne Mørck & Kristensen, Mie, 2023, Cell-Penetrating Peptides: Design, Development and Applications. Oba, M. & Demizu, Y. (eds.). Wiley-VCH, p. 331-354

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  5. Published

    Cell-penetrating antimicrobial peptides - prospectives for targeting intracellular infections

    Bahnsen, J. S., Franzyk, Henrik, Sayers, E. J., Jones, A. T. & Nielsen, Hanne Mørck, 2015, In: Pharmaceutical Research. 32, 5, p. 1546-56 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. The antimicrobial and cell-penetrating effects of the CPP penetratin and derived analogues.

    Bahnsen, J. S., Franzyk, H. & Nielsen, Hanne Mørck, 2012.

    Research output: Contribution to conference › Poster › Research

  7. Håb om at ramme latente bakterier i deres skjul

    Bahnsen, J. S., Water, J. J., Foged, C., Franzyk, H. & Nielsen, Hanne Mørck, 2012, In: Lægemiddelforskning 2012. 2012, p. 12-14

    Research output: Contribution to journal › Journal article › Research

  8. Published

    Håb om at ramme latente bakterier i deres skjul

    Bahnsen, J. S., Water, J. J., Foged, Camilla, Franzyk, Henrik & Nielsen, Hanne Mørck, 2012, In: Lægemiddelforskning 2012. 2012, p. 12-14

    Research output: Contribution to journal › Journal article › Research

  9. Cell-penetrating Peptides Targeting Intracellular Infections

    Bahnsen, J. S., Franzyk, H., Sandberg-Schaal, A. & Nielsen, Hanne Mørck, 2013.

    Research output: Contribution to conference › Poster › Research › peer-review

  10. Published

    Cell-penetrating Peptides Targeting Intracellular Infections

    Bahnsen, J. S., Franzyk, Henrik, Sandberg-Schaal, A. & Nielsen, Hanne Mørck, 2013.

    Research output: Contribution to conference › Poster › Research › peer-review

  11. Published

    Antimicrobial and cell-penetrating properties of penetratin analogs: effect of sequence and secondary structure

    Bahnsen, J. S., Franzyk, Henrik, Sandberg-Schaal, A. & Nielsen, Hanne Mørck, 2013, In: B B A - Biomembranes. 1828, 2, p. 223-232 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    The antimicrobial and cell-penetrating effects of the CPP penetratin and derived analogues.

    Bahnsen, J. S., Franzyk, Henrik & Nielsen, Hanne Mørck, 2012.

    Research output: Contribution to conference › Poster › Research

  13. Published

    Repurposing azithromycin and rifampicin against Gram-negative pathogens by combination with peptide potentiators

    Baker, K. R., Jana, B., Hansen, A. M., Vissing, K. J., Nielsen, Hanne Mørck, Franzyk, Henrik & Guardabassi, Luca, 2019, In: International Journal of Antimicrobial Agents. 53, p. 868-872 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Repurposing Azithromycin and Rifampicin Against Gram-Negative Pathogens by Combination With Peptidomimetics

    Baker, K. R., Jana, B., Hansen, A. M., Nielsen, Hanne Mørck, Franzyk, Henrik & Guardabassi, Luca, 2 Jul 2019, In: Frontiers in Cellular and Infection Microbiology. 9

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    An approach to identify clinically relevan, non-toxic peptide-antimicrobial combinations that eliminate intrinsic resistance in Gram-negative pathogens

    Baker, K. R., Jana, B., Nielsen, Hanne Mørck, Franzyk, Henrik & Guardabassi, Luca, 2017. 1 p.

    Research output: Contribution to conference › Conference abstract for conference › Research

  16. Intact penetratin metabolite permeates across Caco-2 monolayers

    Birch, D., Christensen, M. V., Stærk, D., Franzyk, H. & Nielsen, Hanne Mørck, 2015.

    Research output: Contribution to conference › Poster › Research

  17. Published

    Stereoisomer-Dependent Membrane Association and Capacity for Insulin Delivery Facilitated by Penetratin

    Birch, D., Sayers, E. J., Christensen, M. V., Jones, A. T., Franzyk, Henrik & Nielsen, Hanne Mørck, 2023, In: Pharmaceutics. 15, 6, 15 p., 1672.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Evaluation of drug permeation under fed state conditions using mucus-covered Caco-2 cell epithelium

    Birch, D., Diedrichsen, Ragna Guldsmed, Christophersen, P. C., Mu, Huiling & Nielsen, Hanne Mørck, Jun 2018, In: European Journal of Pharmaceutical Sciences. 118, p. 144-153

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Comparative study of the drug delivery mechanism of L-penetratin and D-penetratin

    Birch, D., Christensen, M. V., Stærk, Dan, Franzyk, Henrik & Nielsen, Hanne Mørck, 2018.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  20. Published

    Stereochemistry as a determining factor for the effect of a cell-penetrating peptide on cellular viability and epithelial integrity

    Birch, D., Christensen, M. V., Stærk, Dan, Franzyk, Henrik & Nielsen, Hanne Mørck, 24 May 2018, In: Biochemical Journal. 475, 10, p. 1773-1788 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Intact penetratin metabolite permeates across Caco-2 monolayers

    Birch, D., Christensen, M. V., Stærk, Dan, Franzyk, Henrik & Nielsen, Hanne Mørck, 2015.

    Research output: Contribution to conference › Poster › Research

  22. Published

    Fluorophore labeling of a cell-penetrating peptide induces differential effects on its cellular distribution and affects cell viability

    Birch, D., Christensen, M. V., Stærk, Dan, Franzyk, Henrik & Nielsen, Hanne Mørck, 2017, In: B B A - Biomembranes. 1859, 12, p. 2483-2494

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Direct observations of drug nanocarrier interactions and mobility within biological interfaces

    Bohr, S. S. R., Streck, S., Pinholt, H., Wan, F., Mcdowell, A., Nielsen, Hanne Mørck & Hatzakis, Nikos, 2022, In: Biophysical Journal. 121, 3, p. 72a-73a 2 p., 355-Pos.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  24. Published

    Drug delivery studies in Caco-2 monolayers. III. Intestinal transport of various vasopressin analogues in the presence of lysophosphatidylcholine

    Brøndsted, H., Nielsen, Hanne Mørck & Hovgaard, L., 14 Feb 1995, In: International Journal of Pharmaceutics. 114, 2, p. 151-157 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Membrane interactions in drug delivery: Model cell membranes and orthogonal techniques

    Bunea, A., Rønholt, Stine, Taboryski, R. & Nielsen, Hanne Mørck, 2020, In: Advances in Colloid and Interface Science. 281, 15 p., 102177.

    Research output: Contribution to journal › Review › Research › peer-review

  26. Mucosal drug delivery: barriers, in vitro models and formulation strategies

    Bøgh, M., Foged, C., Müllertz, A. & Nielsen, Hanne Mørck, 2013, In: Journal of Drug Delivery Science and Technology. 23, 4, p. 383-391

    Research output: Contribution to journal › Review › Research › peer-review

  27. Published

    Development and rheological profiling of biosimilar mucus

    Bøgh, M., Baldursdottir, S. G., Nielsen, M. H., Mullertz, Anette & Nielsen, Hanne Mørck, 2013, In: Nordic Rheology Society Annual Transactions. 21, p. 233-240

    Research output: Contribution to journal › Conference article › Research › peer-review

  28. Published

    Property profiling of biosimilar mucus in a novel mucus-containing in vitro model for assessment of intestinal drug absorption

    Bøgh, M., Baldursdóttir, S. G., Mullertz, Anette & Nielsen, Hanne Mørck, 8 Jan 2014, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 87, p. 227-235 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Mucus as a Barrier to Drug Delivery: Understanding and Mimicking the Barrier Properties

    Bøgh, M. & Nielsen, Hanne Mørck, Mar 2015, In: Basic & Clinical Pharmacology & Toxicology. 116, 3, p. 179-186 8 p.

    Research output: Contribution to journal › Review › Research › peer-review

  30. Development and rheological profiling of biosimilar mucus

    Bøgh, M., Baldursdottir, S. G., Nielsen, M. H., Müllertz, A. & Nielsen, Hanne Mørck, 2013, In: Nordic Rheology Society Annual Transactions. 21, p. 233-240

    Research output: Contribution to journal › Conference article › Research › peer-review

  31. Published

    Mucosal drug delivery: barriers, in vitro models and formulation strategies

    Bøgh, M., Foged, Camilla, Mullertz, Anette & Nielsen, Hanne Mørck, 2013, In: Journal of Drug Delivery Science and Technology. 23, 4, p. 383-391

    Research output: Contribution to journal › Review › Research › peer-review

  32. Published

    Steric and interactive barrier properties of intestinal mucus elucidated by particle diffusion and peptide permeation

    Bøgh, M., García-Díaz, M., Mullertz, Anette & Nielsen, Hanne Mørck, Sep 2015, In: European Journal of Pharmaceutics and Biopharmaceutics. 94, Part A, p. 136–143 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    In vitro placental model optimization for nanoparticle transport studies

    Cartwright, L., Poulsen, M. S., Nielsen, Hanne Mørck, Pojana, G., Knudsen, Lisbeth E., Saunders, M. & Rytting, E., 2012, In: International Journal of Nanomedicine (Online). 7, p. 497-510

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    In vitro placental model optimization for nanoparticle transport studies

    Cartwright, L., Poulsen, M. S., Nielsen, Hanne Mørck, Pojana, G., Knudsen, Lisbeth E., Saunders, M. & Rytting, E., 2012, In: International Journal of Nanomedicine (Print). 7, p. 497-510 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Trehalose preserves DDA/TDB liposomes and their adjuvant effect during freeze-drying

    Christensen, D., Foged, Camilla, Rosenkrands, I., Nielsen, Hanne Mørck, Andersen, P. & Agger, E. M., 2007, In: BBA General Subjects. 1768, 9, p. 2120-2129

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    a, a´- trehalose 6,6´- dibehenate in non-phospholipid-based liposomes enables direct interaction with trehalose, offering stability during freeze-drying

    Christensen, D., Kirby, D., Foged, Camilla, Agger, E. M., Andersen, P., Perrie, Y. & Nielsen, Hanne Mørck, 2008, In: Biochimica et Biophysica Acta - Biomembranes. 1778, 5, p. 1365-1373

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    NIR transmission spectroscopy for rapid determination of lipid and lyoprotector content in liposomal vaccine adjuvant system CAF01

    Christensen, D., Allesø, M., Rosenkrands, I., Rantanen, Jukka, Foged, Camilla, Agger, E. M., Andersen, P. & Nielsen, Hanne Mørck, 2008, In: European Journal of Pharmaceutics and Biopharmaceutics. 70, 3, p. 914-920

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    CAF01 liposomes as a mucosal vaccine adjuvant: In vitro and in vivo investigations

    Christensen, D., Foged, Camilla, Rosenkrands, I., Lundberg, C. V., Andersen, P., Agger, E. M. & Nielsen, Hanne Mørck, 2010, In: Internation Journal of Pharmaceutics. 390, p. 19-24

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    19F-substituted amino acids as an alternative to fluorophore labels: monitoring of degradation and cellular uptake of analogues of penetratin by 19F NMR

    Christensen, M. V., Kongstad, Kenneth Thermann, Sondergaard, T. E., Stærk, Dan, Nielsen, Hanne Mørck, Franzyk, Henrik & Wimmer, R., 2019, In: Journal of Biomolecular N M R. 73, p. 167-182

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Trilaurin diminishes food effect on the release of desmopressin from solid lipid microparticles

    Christophersen, P., Vaghela, D., Mullertz, Anette , Yang, Mingshi, Nielsen, Hanne Mørck & Mu, Huiling, 2014.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  41. Trilaurin diminishes food effect on the release of desmopressin from solid lipid microparticles

    Christophersen, P., Vaghela, D., Müllertz, A., Yang, M., Nielsen, Hanne Mørck & Mu, H., 2014.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  42. Published

    Solid lipid particles for oral delivery of peptide and protein drugs III - the effect of fed state conditions on the in vitro release and degradation of desmopressin

    Christophersen, P. C., Vaghela, D., Mullertz, Anette , Yang, Mingshi, Nielsen, Hanne Mørck & Mu, Huiling, Jul 2014, In: A A P S Journal. 16, 4, p. 875-83 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Investigation of protein distribution in solid lipid particles and its impact on protein release using coherent anti-Stokes Raman scattering microscopy

    Christophersen, P. C., Birch, D., Saarinen, J., Isomäki, A., Nielsen, Hanne Mørck, Yang, Mingshi, Strachan, C. J. & Mu, Huiling, 10 Jan 2015, In: Journal of Controlled Release. 197, p. 111-120 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Solid Lipid Particles for Oral Delivery of Peptide and Protein Drugs II - The Digestion of Trilaurin Protects Desmopressin from Proteolytic Degradation

    Christophersen, P. C., Zhang, L., Mullertz, Anette , Nielsen, Hanne Mørck, Yang, Mingshi & Mu, Huiling, 13 Mar 2014, In: Pharmaceutical Research. 31, 9, p. 2420-28 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Characterization of particulate drug delivery systems for oral delivery of Peptide and protein drugs

    Christophersen, P. C., Fano, M., Saaby, Lasse, Yang, Mingshi, Nielsen, Hanne Mørck & Mu, Huiling, 2015, In: Current Pharmaceutical Design. 21, 19, p. 2611-28 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Solid lipid particles for oral delivery of peptide and protein drugs I - Elucidating the release mechanism of lysozyme during lipolysis

    Christophersen, P. C. B., Zhang, L., Yang, Mingshi, Nielsen, Hanne Mørck, Mullertz, Anette & Mu, Huiling, 2 Aug 2013, In: European Journal of Pharmaceutics and Biopharmaceutics. 85, 3, part A, p. 473-480

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Solid-phase route to Fmoc-protected cationic amino acid building blocks

    Clausen, J. D., Linderoth, L., Nielsen, Hanne Mørck & Franzyk, Henrik, 2012, In: Amino Acids. 43, 4, p. 1633-41 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Mucoadhesive Electrospun Patch Delivery of Lidocaine to the Oral Mucosa and Investigation of Spatial Distribution in a Tissue Using MALDI-Mass Spectrometry Imaging

    Clitherow, K. H., Murdoch, C., Spain, S. G., Handler, A. M., Colley, H. E., Stie, Mai Bay, Nielsen, Hanne Mørck, Janfelt, Christian, Hatton, P. V. & Jacobsen, Jette, Sep 2019, In: Molecular Pharmaceutics. 16, 9, p. 3948-3956

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Mechanistic profiling of the siRNA delivery dynamics of lipid-polymer hybrid nanoparticles

    Colombo, S., Cun, D., Remaut, K., Bunker, M., Zhang, J., Martin-Bertelsen, Birte, Yaghmur, Anan, Braeckmans, K., Nielsen, Hanne Mørck & Foged, Camilla, 10 Mar 2015, In: Journal of Controlled Release. 201, p. 22-31 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Evaluation of carrier-mediated siRNA delivery: lessons for the design of a stem-loop qPCR-based approach for quantification of intracellular full-length siRNA

    Colombo, S., Nielsen, Hanne Mørck & Foged, Camilla, 11 Jan 2013, In: Journal of Controlled Release. 166, 3, p. 220-226 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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ID: 1299091