Christian Janfelt

Christian Janfelt

Associate Professor - Promotion Programme


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  1. Published

    A Comparison of Human and Porcine Skin in Laser-Assisted Drug Delivery of Chemotherapeutics

    Rosenberg, L. K., Bagger, C., Janfelt, Christian, Hædersdal, Merete, Olesen, U. H. & Lerche, Catharina Margrethe, 2021, In: Lasers in Surgery and Medicine. 53, 1, p. 162-170 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    A one-time pneumatic jet-injection of 5-fluorouracil and triamcinolone acetonide for treatment of hypertrophic scars: A blinded randomized controlled trial

    Erlendsson, A. M., Rosenberg, L. K., Lerche, Catharina Margrethe, Togsverd-Bo, K., Wiegell, Stine Regin, Karmisholt, Katrine Elisabeth, Philipsen, P. A., Hansen, Anders Christian Nørgaard, Janfelt, Christian, Holmes, J., Rossi, A. & Hædersdal, Merete, 2022, In: Lasers in Surgery and Medicine. 54, 5, p. 663-671

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Ambient Mass Spectrometry with a Handheld Mass Spectrometer at High Pressure

    Keil, A., Talaty, N., Janfelt, Christian, Noll, R. J., Gao, L., Ouyang, Z. & Cooks, R. G., 2007, In: Analytical Chemistry. 79, p. 7734-7739 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Ambient mass spectrometry imaging: a comparison of desorption ionization by sonic spray and electrospray

    Janfelt, Christian & Nørgaard, A. W., Oct 2012, In: Journal of The American Society for Mass Spectrometry. 23, 10, p. 1670-8 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Analysis of secondary plant metabolites by indirect desorption electrospray ionization imaging mas spectrometry

    Thunig, U. J. C., Hansen, S. H. & Janfelt, Christian, 2011, In: Analytical Chemistry. 83, p. 3256-3259

    Research output: Contribution to journal › Letter › Research › peer-review

  6. Published

    Aspects of Quantitation in Mass Spectrometry Imaging Investigated on Cryo-Sections of Spiked Tissue Homogenates

    Hansen, H. T. & Janfelt, Christian, 2016, In: Analytical Chemistry. 88, 23, p. 11513−11520 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Azone® decreases the buccal mucosal permeation of Diazepam in a concentration-dependent manner via a reservoir effect

    Meng-Lund, E., Jacobsen, Jette, Jin, L., Janfelt, Christian, Holm, R., Mullertz, Anette & Nicolazzo, J. A., 15 Feb 2014, In: Journal of Pharmaceutical Sciences. 103, 4, p. 1133-1141 103.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Billeddannende massespektrometri

    Janfelt, Christian, D'Alvise, J., Li, B. & Hansen, S. H., 2012, In: Dansk Kemi. 93, 6/7, p. 12-14 3 p.

    Research output: Contribution to journal › Journal article › Communication

  9. Published

    Billeddannende massespektrometri til analyse af vævsprøver

    Janfelt, Christian, Wellner, N., D'Alvise, J. & Hansen, S. H., 2012, In: Dansk Kemi. 93, 8, p. 20-23

    Research output: Contribution to journal › Journal article › Research

  10. Published

    Bleomycin administered by laser-assisted drug delivery or intradermal needle-injection results in distinct biodistribution patterns in skin: in vivo investigations with mass spectrometry imaging

    Hendel, K., Hansen, Anders Christian Nørgaard, Bik, L., Bagger, C., van Doorn, M. B. A., Janfelt, Christian, Olesen, U. H., Hædersdal, Merete & Lerche, Catharina Margrethe, 1 Jan 2021, In: Drug Delivery. 28, 1, p. 1141-1149 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Buccal delivery of small molecules - Impact of levulinic acid, oleic acid, sodium dodecyl sulfate and hypotonicity on ex vivo permeability and spatial distribution in mucosa

    Hansen, S. E., Marxen, E., Janfelt, Christian & Jacobsen, Jette, Dec 2018, In: European Journal of Pharmaceutics and Biopharmaceutics. 133, p. 250-257

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Characterisation and localisation of the endocannabinoid system components in the adult human testis

    Nielsen, J. E., Rolland, A. D., Rajpert-De Meyts, E., Janfelt, Christian, Jørgensen, A., Winge, S. B., Kristensen, D. M., Juul, Anders, Chalmel, F., Jégou, B. & Skakkebæk, Niels Erik, 2019, In: Scientific Reports. 9, 1, 14 p., 12866.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Characterization and optimization of membrane inlets for a miniature ion trap mass spectrometer operating at a high background pressure of humid air

    Janfelt, Christian, Graesboll, R. & Lauritsen, F. R., 2008, In: International Journal of Mass Spectrometry. 276, p. 17-23 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Characterization of a capillary spray cell for easy analysis of extracts of biological samples

    Janfelt, Christian & Lauritsen, F. R., 2011, In: International Journal of Mass Spectrometry. 299, p. 178-183

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Characterization of a mini membrane inlet mass spectrometer for on-site detection of contaminants in both aqueous and liquid organic samples

    Janfelt, Christian, Frandsen, H. & Lauritsen, F. R., 2006, In: Rapid Communications in Mass Spectrometry. 20, p. 1441–1446 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Characterization of barley leaf tissue using direct and indirect desorption electrospray ionization imaging mass spectrometry

    Li, B., Bjarnholt, Nanna, Hansen, S. H. & Janfelt, Christian, 2011, In: Journal of Mass Spectrometry. 46, 12, p. 1241-1246

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Characterization of midazolam metabolism in locusts: The role of CYP3A4-like enzyme in the formation of 1'-OH and 4-OH midazolam

    Olsen, L. R., Gabel-Jensen, C., Wubshet, S. G., Kongstad, Kenneth Thermann, Janfelt, Christian, Badolo, L. & Hansen, S. H., 2016, In: Xenobiotica. 46, 2, p. 99–107 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Characterizing Cutaneous Drug Delivery Using Open-Flow Microperfusion and Mass Spectrometry Imaging

    Handler, A. M., Eirefelt, S., Lambert, M., Johansson, F., Hollesen Schefe, L., Knudsen, N. Ø., Bodenlenz, M., Birngruber, T., Sinner, F., Eriksson, A. H., Pedersen, G. P., Janfelt, Christian & Troensegaard Nielsen, K., 2021, In: Molecular Pharmaceutics. 18, 8, p. 3063-3072

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Combination of MALDI-MSI and cassette dosing for evaluation of drug distribution in human skin explant

    Sørensen, I. S., Janfelt, Christian, Nielsen, M. M. B., Mortensen, R. W., Knudsen, N. Ø., Eriksson, A. H., Pedersen, A. J. & Nielsen, K. T., Aug 2017, In: Analytical and Bioanalytical Chemistry. 409, 21, p. 4993-5005 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Cryo-sectioning of mice for whole-body imaging of drugs and metabolites with desorption electrospray ionization mass spectrometry imaging - a simplified approach

    Okutan, S., Hansen, Harald S. & Janfelt, Christian, Jun 2016, In: Proteomics. 16, 11-12, p. 1633-41 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    DESI-MS imaging of metabolites in various plant materials – a matter of sample preparation

    Kato, L., Rook, F., Møller, Birger Lindberg, Hansen, S. H. & Janfelt, Christian, 2015.

    Research output: Contribution to conference › Poster › Research

  22. Published

    Delivery of amitriptyline by intravenous and intraperitoneal administration compared in the same animal by whole-body mass spectrometry imaging of a stable isotope labelled drug substance in mice

    Morineau, L., Jacobsen, S. C., Kleberg, K., Hansen, Harald S. & Janfelt, Christian, 2 Dec 2018, In: Expert Opinion on Drug Delivery. 15, 12, p. 1157-1163

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Desorption Electrospray Ionization Mass Spectrometry Imaging of Cimbi-36, a 5-HT2A Receptor Agonist, with Direct Comparison to Autoradiography and Positron Emission Tomography

    Jacobsen, S. C., Speth, N. R., Xiong, M., Herth, Matthias Manfred, Kristensen, Jesper Langgaard, Palner, M. & Janfelt, Christian, 2021, In: Molecular Imaging and Biology. 23, p. 676–685

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Detection of follicular transport of lidocaine and metabolism in adipose tissue in pig ear skin by DESI mass spectrometry imaging

    D'Alvise, J., Mortensen, R., Hansen, S. H. & Janfelt, Christian, Jun 2014, In: Analytical and Bioanalytical Chemistry. 406, 15, p. 3735-42 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Developing a predictive in vitro dissolution model based on gastrointestinal fluid characterisation in rats

    Christfort, J. F., Strindberg, S., Plum, J., Hall-Andersen, J., Janfelt, Christian, Nielsen, L. H. & Mullertz, Anette , 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 142, p. 307-314 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Direct and indirect imaging of secondary metabolites and enzymatic reactions in plant material by Desorption Electrospray Ionization

    Li, B., Bjarnholt, Nanna, Knudsen, C., D'Alvise, J., Hansen, S. H. & Janfelt, Christian, 2012.

    Research output: Contribution to conference › Poster › Research › peer-review

  27. Published

    Direct imaging of plant metabolites in leaves and petals by Desorption Electrospray Ionization mass spectrometry

    Li, B., Hansen, S. H. & Janfelt, Christian, 2013, In: International Journal of Mass Spectrometry. 348, p. 15-22

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Direkte analyse med DESI-MS

    Thunig, J., Lauritsen, F. R., Hansen, S. H., Janfelt, Christian & Christophersen, C., 2010, In: Dansk Kemi. 91, 3, p. 21-23 3 p.

    Research output: Contribution to journal › Journal article › Research

  29. Published

    Displaced dual-mode imaging with desorption electrospray ionization for simultaneous mass spectrometry imaging in both polarities and with several scan modes

    Janfelt, Christian, Wellner, N., Hansen, Harald S. & Hansen, S. H., Mar 2013, In: Journal of Mass Spectrometry. 48, 3, p. 361-6 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Distribution of terfenadine and its metabolites in locusts studied by desorption electrospray ionization mass spectrometry imaging

    Olsen, L. R., Hansen, S. H. & Janfelt, Christian, 2015, In: Analytical and Bioanalytical Chemistry. 407, 8, p. 2149–2158 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Effect of Permeation Enhancers on the Buccal Permeability of Nicotine: Ex vivo Transport Studies Complemented by MALDI MS Imaging

    Marxen, E., Jin, L., Jacobsen, Jette, Janfelt, Christian, Hyrup, B. & Nicolazzo, J. A., 21 Feb 2018, In: Pharmaceutical Research. 35, 3, 12 p., 70.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Efficacy and Safety of Laser‐Assisted Combination Chemotherapy: An Explorative Imaging‐Guided Treatment With 5‐Fluorouracil and Cisplatin for Basal Cell Carcinoma

    Wenande, E., Hendel, K., Mogensen, Mette, Bagger, C., Mårtensson, Nina Løth, Persson, Daniel Pergament, Lerche, C. M., Husted, Søren, Janfelt, Christian, Togsverd‐bo, K., Anderson, R. R. & Hædersdal, Merete, 2021, In: Lasers in Surgery and Medicine. 53, 1, p. 119-128 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Electrospun α-lactalbumin nanofibers for site-specific and fast-onset delivery of nicotine in the oral cavity: an in vitro, ex vivo and tissue spatial distribution study

    Kalouta, Kleopatra, Stie, Mai Bay, Janfelt, Christian, Chronakis, I. S., Jacobsen, Jette, Nielsen, Hanne Mørck & Foderà, Vito, 2020, In: Molecular Pharmaceutics. 17, 11, p. 4189-4200

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Elucidating the spatial distribution of organic contaminants and their biotransformation products in amphipod tissue by MALDI- and DESI-MS-imaging

    Raths, J., Pinto, F. E., Janfelt, Christian & Hollender, J., 2023, In: Ecotoxicology and Environmental Safety. 264, 10 p., 115468.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Fast and direct screening of polyaromatic hydrocarbon (PAH)-contaminated sand using a miniaturized membrane inlet mass spectrometer (mini-MIMS)

    Frandsen, H., Janfelt, Christian & Lauritsen, F. R., 2007, In: Rapid Communications in Mass Spectrometry. 21, p. 1574-1578 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Fractional laser-assisted drug delivery: Laser channel depth influences biodistribution and skin deposition of methotrexate

    Taudorf, E. H., Lerche, C. M., Erlendsson, A. M., Philipsen, P. A., Hansen, S. H., Janfelt, Christian, Paasch, U., Anderson, R. R. & Hædersdal, Merete, Jul 2016, In: Lasers in Surgery and Medicine. 48, 5, p. 519-529 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Fractional laser-assisted topical delivery leads to enhanced, accelerated and deeper cutaneous 5-fluorouracil uptake

    Wenande, E., Olesen, U. H., Nielsen, M. M. B., Janfelt, Christian, Hansen, S. H., Anderson, R. & Hædersdal, Merete, 2017, In: Expert Opinion on Drug Delivery. 14, 3, p. 307-317 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Fractional laser-assisted topical delivery of bleomycin quantified by LC-MS and visualized by MALDI mass spectrometry imaging

    Hendel, K. K., Bagger, C., Olesen, U. H., Janfelt, Christian, Hansen, S. H., Hædersdal, Merete & Lerche, C. M., Dec 2019, In: Drug Delivery. 26, 1, p. 244-251 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    High-throughput analysis of drugs in biological fluids by desorption electrospray ionization mass spectrometry coupled with thin liquid membrane extraction

    Rosting, C., Pedersen-Bjergaard, Stig, Hansen, S. H. & Janfelt, Christian, 2013, In: Analyst. 138, 20, p. 5965-72 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Imaging of plant materials using indirect desorption electrospray ionization mass spectrometry

    Janfelt, Christian, 2015, Mass Spectrometry Imaging of Small Molecules. He, L. (ed.). Humana Press, Vol. 1203. p. 91-7 7 p. (Methods in Molecular Biology).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  41. Published

    Importance of Dietary Uptake for in Situ Bioaccumulation of Systemic Fungicides Using Gammarus pulex as a Model Organism

    Raths, J., Schnurr, J., Bundschuh, M., Pinto, F. E., Janfelt, Christian & Hollender, J., 2023, In: Environmental Toxicology and Chemistry. 42, 9, p. 1993-2006

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    In Vitro and In Vivo Evaluation of Pellotine: A Hypnotic Lophophora Alkaloid

    Poulie, C. B. M., Chan, C. B., Parka, A., Lettorp, M., Vos, J., Raaschou, A., Pottie, E., Bundgaard, M. S., Sørensen, L. M. E., Cecchi, C. R., Märcher-Rørsted, E., Bach, A., Herth, M. M., Decker, A., Jensen, A. A., Elfving, B., Kretschmann, A. C., Stove, C. P., Kohlmeier, K. A., Cornett, C. & 3 others, Janfelt, Christian, Kornum, Birgitte Rahbek & Kristensen, Jesper Langgaard, 2023, In: ACS Pharmacology & Translational Science. 6, 10, p. 1492-1507

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    In vivo dermal delivery of bleomycin with electronic pneumatic injection: drug visualization and quantification with mass spectrometry

    Bik, L., van Doorn, M., Hansen, Anders Christian Nørgaard, Janfelt, Christian, Olesen, U. H., Hædersdal, Merete, Lerche, Catharina Margrethe & Hendel, K., 2022, In: Expert Opinion on Drug Delivery. 19, 2, p. 213-219

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Indirect DESI imaging of secondary metabolites in plant material

    Janfelt, Christian, Thunig, U. J. C., Li, B. & Hansen, S. H., 2011. 1 p.

    Research output: Contribution to conference › Poster › Research

  45. Published

    Interspecific variation in localization of hypericins and phloroglucinols in the genus Hypericum as revealed by desorption electrospray ionization mass spectrometry imaging

    Kucharíková, A., Kimáková, K., Janfelt, Christian & Cellárová, E., 2016, In: Physiologia Plantarum. 157, 1, p. 2-12 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Intrapulmonary (i.pulmon.) Pull Immunization With the Tuberculosis Subunit Vaccine Candidate H56/CAF01 After Intramuscular (i.m.) Priming Elicits a Distinct Innate Myeloid Response and Activation of Antigen-Presenting Cells Than i.m. or i.pulmon. Prime Immunization Alone

    Thakur, A., Pinto, F. E., Hansen, Harald S., Andersen, Peter, Christensen, D., Janfelt, Christian & Foged, Camilla, 2020, In: Frontiers in Immunology. 11, p. 803

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Ischemia in neonatal rat brains analyzed by Desorption Electrospray Ionization Imaging mass spectrometry

    Janfelt, Christian, Wellner, N., Leger, P., Kokesch-Himmelreich, J., Hansen, S. H., Charriaut-Marlangue, C. & Hansen, Harald S., 2012.

    Research output: Contribution to conference › Poster › Research › peer-review

  48. Published

    Kan analyselaboratoriet flyttes i felten?

    Janfelt, Christian & Lauritsen, F. R., 2008, In: LMFK-Bladet. 1, p. 31-34 4 p.

    Research output: Contribution to journal › Journal article › Commissioned

  49. Published

    Leaves of Cannabis sativa and their trichomes studied by DESI and MALDI mass spectrometry imaging for their contents of cannabinoids and flavonoids

    Lorensen, Marcus Daniel B B, Hayat, S. Y., Wellner, N., Bjarnholt, Nanna & Janfelt, Christian, 2023, In: Phytochemical Analysis. 34, 3, p. 269-279

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Liquid-Phase MicroExtraction coupled to Desorption Electrospray Ionization Mass Spectrometry in pharmaceutical analysis

    Janfelt, Christian, Thunig, U. J. C., Pedersen-Bjergaard, Stig & Hansen, S. H., 2009.

    Research output: Contribution to conference › Poster › Research

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