Camilla Foged
Professor
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Immunogenicity Testing of Lipidoids In Vitro and In Silico: Modulating Lipidoid-Mediated TLR4 Activation by Nanoparticle Design
de Groot, A. M., Thanki, K., Gangloff, M., Falkenberg, E., Zeng, X., van Bijnen, D. C. J., van Eden, W., Franzyk, Henrik, Nielsen, Hanne Mørck, Broere, F., Gay, N. J., Foged, Camilla & Sijts, A. J. A. M., 1 Jun 2018, In: Molecular Therapy - Nucleic Acids. 11, p. 159-169 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Surface coating of siRNA-peptidomimetic nano-self-assemblies with anionic lipid bilayers: Enhanced gene silencing and reduced adversed effects in vitro
Zeng, X., de Groot, A. M., Sijts, A., Blenke, E. O., Colombo, S., van Eden, W., Franzyk, Henrik, Nielsen, Hanne Mørck & Foged, Camilla, 2015, In: Nanoscale. 7, 46, p. 19687-19698 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Quality-by-design in nanomedicine: Highly systematic optimization of lipid-polymer hybrid nanoparticles for efficacious and safe intracellular delivery of cargo siRNA
Zeng, X., Nielsen, Hanne Mørck, Franzyk, Henrik & Foged, Camilla, 2017.Research output: Contribution to conference › Conference abstract for conference › Research
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Effect of lipid-polymer hybrid nanoparticles on the biophysical function and lateral structure of pulmonary surfactant: Mechanistic in vitro studies
Xu, Y., Cañadas, O., Alonso, A., Franzyk, Henrik, Thakur, A., Pérez-gil, J. & Foged, Camilla, 2024, In: Journal of Colloid and Interface Science. 654, Part B, p. 1111-1123Research output: Contribution to journal › Journal article › Research › peer-review
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Inhalable Composite Microparticles Containing siRNA-Loaded Lipid-Polymer Hybrid Nanoparticles: Saccharides and Leucine Preserve Aerosol Performance and Long-Term Physical Stability
Xu, You, Turan, E. T., Shi, Z., Franzyk, Henrik, Thakur, A. & Foged, Camilla, 2022, In: Frontiers in Drug Delivery. 2, 15 p., 945459.Research output: Contribution to journal › Journal article › Research › peer-review
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Inhaled RNA Therapeutics for Obstructive Airway Diseases: Recent Advances and Future Prospects
Xu, You, Thakur, A., Zhang, Y. & Foged, Camilla, 2021, In: Pharmaceutics. 13, 2, 35 p., 77.Research output: Contribution to journal › Review › Research › peer-review
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Insights into the mechanisms of interaction between inhalable lipid-polymer hybrid nanoparticles and pulmonary surfactant
Xu, Y., Parra-Ortiz, E., Wan, F., Cañadas, O., Garcia-Alvarez, B., Thakur, A., Franzyk, Henrik, Pérez-Gil, J., Malmsten, Martin & Foged, Camilla, 2023, In: Journal of Colloid and Interface Science. 633, p. 511-525Research output: Contribution to journal › Journal article › Research › peer-review
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Leucine improves the aerosol performance of dry powder inhaler formulations of siRNA-loaded nanoparticles
Xu, Y., Harinck, L., Lokras, Abhijeet, Gerde, P., Selg, E., Sjöberg, C., Franzyk, Henrik, Thakur, A. & Foged, Camilla, 2022, In: International Journal of Pharmaceutics. 621, 14 p., 121758.Research output: Contribution to journal › Journal article › Research › peer-review
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Adsorption of protein antigen to the cationic liposome adjuvant CAF®01 is required for induction of Th1 and Th17 responses but not for antibody induction
Wørzner, K., Hvannastein, J., Tandrup Schmidt, S., Foged, Camilla, Rosenkrands, I., Kristian Pedersen, G. & Christensen, D., 2021, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 165, p. 293-305Research output: Contribution to journal › Journal article › Research › peer-review
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Advances in combination therapy of lung cancer: Rationales, delivery technologies and dosage regimens
Wu, L., Leng, D., Cun, D., Foged, Camilla & Yang, Mingshi, Aug 2017, In: Journal of Controlled Release. 260, p. 78-91Research output: Contribution to journal › Journal article › Research › peer-review
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Nanoparticle-mediated delivery of the antimicrobial peptide plectasin against Staphylococcus aureus in infected epithelial cells
Water, J. J., Smart, S., Franzyk, Henrik, Foged, Camilla & Nielsen, Hanne Mørck, 18 Feb 2015, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 92, p. 65-73 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Loading of an antimicrobial peptide into PLGA nanoparticles increases its efficacy against intracellular Staphylococcus aureus infection in the Calu-3 bronchial epithelial cell line
Water, J. J., Foged, Camilla, Franzyk, Henrik & Nielsen, Hanne Mørck, 2013.Research output: Contribution to conference › Poster › Research › peer-review
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Improving the safety profile of an antimicrobial peptide: Self-assembly into hydrogel nanoparticles using microfluidics
Water, J. J., Maltesen, M. J., Foged, Camilla, Franzyk, Henrik & Nielsen, Hanne Mørck, 2014.Research output: Contribution to conference › Poster › Research › peer-review
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Hyaluronic Acid-Based Nanogels Produced by Microfluidics-Facilitated Self-Assembly Improves the Safety Profile of the Cationic Host Defense Peptide Novicidin
Water, J. J., Kim, Y., Maltesen, M. J., Franzyk, Henrik, Foged, Camilla & Nielsen, Hanne Mørck, Aug 2015, In: Pharmaceutical Research. 32, 8, p. 2727-35 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Particle engineering technologies for improving the delivery of peptide and protein drugs
Wan, F., Maltesen , M. J., Bjerregaard, S., Foged, Camilla, Rantanen, Jukka & Yang, Mingshi, 2013, In: Journal of Drug Delivery Science and Technology. 23, 4, p. 355-363Research output: Contribution to journal › Journal article › Research › peer-review
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Qualitative and quantitative analysis of the biophysical interaction of inhaled nanoparticles with pulmonary surfactant by using quartz crystal microbalance with dissipation monitoring
Wan, F., Nylander, T., Foged, Camilla, Yang, Mingshi, Baldursdottir, S. G. & Nielsen, Hanne Mørck, 1 Mar 2019, In: Journal of Colloid and Interface Science. 545, p. 162-171 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Impact of PLGA molecular behavior in the feed solution on the drug release kinetics of spray dried microparticles
Wan, F., Wu, J., Bohr, A. J., Baldursdottir, S. G., Maltesen, M. J., Foged, Camilla, Rantanen, Jukka & Yang, Mingshi, 2013, In: Polymer. 54, 21, p. 5920-5927Research output: Contribution to journal › Journal article › Research › peer-review
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PLGA conformational behaviour dependence of the network characterized by rheological study
Wan, F., Baldursdottir, S. G., Maltesen, M. J., Bjerregaard, S., Foged, Camilla, Rantanen, Jukka & Yang, Mingshi, 2013, In: Nordic Rheology Society Annual Transactions. 21, p. 357-361Research output: Contribution to journal › Conference article › Research
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Organization and evolution of PLGA network characterized by rheological study
Wan, F., Baldursdottir, S. G., Maltesen, M. J., Bjerregaard, S. & Foged, Camilla, 2013, In: Nordic Rheology Society Annual Transactions. 21Research output: Contribution to journal › Conference article › Research
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One-Step Production of Protein-Loaded PLGA Microparticles via Spray Drying Using 3-Fluid Nozzle
Wan, F., Maltesen, M. J., Andersen, S. K., Bjerregaard, S., Foged, Camilla, Rantanen, Jukka & Yang, Mingshi, 19 Feb 2014, In: Pharmaceutical Research. 31, 8, p. 1969-1977 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Modulating protein release profiles by incorporating hyaluronic acid into PLGA microparticles Via a spray dryer equipped with a 3-fluid nozzle
Wan, F., Maltesen, M. J., Andersen, S. K., Bjerregaard, S., Baldursdottir, S. G., Foged, Camilla, Rantanen, Jukka & Yang, Mingshi, Nov 2014, In: Pharmaceutical Research. 31, 11, p. 2940-51 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Lipid shell-enveloped polymeric nanoparticles with high integrity of lipid shells improve mucus penetration and interaction with cystic fibrosis-related bacterial biofilms
Wan, F., Nylander, T., Klodzinska, S. N., Foged, Camilla, Yang, Mingshi, Baldursdottir, S. G. & Nielsen, Hanne Mørck, 23 Feb 2018, In: A C S Applied Materials and Interfaces. 10, 13, p. 10678–10687Research output: Contribution to journal › Journal article › Research › peer-review
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Insight into Nanoscale Network of Spray-dried Polymeric Particles: Role of Polymer Molecular Conformation
Wan, F., Larsen, F. H., Nunes Bordallo, Heloisa, Foged, Camilla, Rantanen, Jukka & Yang, Mingshi, 2018, In: A C S Applied Materials and Interfaces. 10, 43, p. 36686-36692Research output: Contribution to journal › Journal article › Research › peer-review
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Critical solvent properties affecting the particle formation process and characteristics of celecoxib-loaded PLGA microparticles via spray-drying
Wan, F., Bohr, A., Maltesen, M. J., Bjerregaard, S., Foged, Camilla, Rantanen, Jukka & Yang, Mingshi, Apr 2013, In: Pharmaceutical Research. 30, 4, p. 1065-1076Research output: Contribution to journal › Journal article › Research › peer-review
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Opportunities and Challenges in the Delivery of mRNA-based Vaccines
Wadhwa, A., Aljabbari, A., Lokras, Abhijeet, Foged, Camilla & Thakur, A., 28 Jan 2020, In: Pharmaceutics. 12, 2, 27 p., 102.Research output: Contribution to journal › Review › Research › peer-review
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Pulmonary delivery of siRNA-loaded lipid-polymer hybrid nanoparticles: Effect of nanoparticle size
Wadhwa, A., Bobak, T. R., Bohrmann, L., Geczy, R., Sekar, S., Sathyanarayanan, G., Kutter, Jörg P., Franzyk, Henrik, Foged, Camilla, Saatchi, K. & Häfeli, U. O., 2023, In: OpenNano. 13, 12 p., 100180.Research output: Contribution to journal › Journal article › Research › peer-review
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Nebulised lipid-polymer hybrid nanoparticles for the delivery of a therapeutic anti-inflammatory microRNA to bronchial epithelial cells
Vencken, S., Foged, Camilla, Ramsey, J. M., Sweeney, L., Cryan, S., MacLoughlin, R. J. & Greene, C. M., Apr 2019, In: ERJ Open Research. 5, 2, 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Antiplasmodial and prehemolytic activities of alpha-peptide-beta-peptoid chimeras
Vedel, L., Bonke, G., Foged, Camilla, Ziegler, H. L., Franzyk, Henrik, Jaroszewski, J. W. & Olsen, Christian Adam, 2007, In: ChemBioChem. 8, 15, p. 1781-1784 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Application of a Quality-By-Design Approach to Optimise Lipid-Polymer Hybrid Nanoparticles Loaded with a Splice-Correction Antisense Oligonucleotide: Maximising Loading and Intracellular Delivery
Thanki, K., Papai, S., Lokras, Abhijeet, Rose, F., Falkenberg, E., Franzyk, Henrik & Foged, Camilla, 2019, In: Pharmaceutical Research. 36, 3, 37.Research output: Contribution to journal › Journal article › Research › peer-review
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Efficient Pulmonary Delivery of siRNA Using Lipid-polymer Hybrid Nanoparticles (LPNs): A quality-by-design approach for highly systematic optimization of LPNs
Thanki, K., Zeng, X., Justesen, S., Tejlmann, S., Falkenberg, E., Nielsen, Hanne Mørck, Franzyk, Henrik & Foged, Camilla, 2017.Research output: Contribution to conference › Poster › Research
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Mechanistic profiling of the release kinetics of siRNA from lipidoid-polymer hybrid nanoparticles in vitro and in vivo after pulmonary administration
Thanki, K., van Eetvelde, D., Geyer, A., Fraire, J., Hendrix, R., Van Eygen, H., Putteman, E., Sami, H., de Souza Carvalho-Wodarz, C., Franzyk, Henrik, Nielsen, Hanne Mørck, Braeckmans, K., Lehr, C., Ogris, M. & Foged, Camilla, 2019, In: Journal of controlled release : official journal of the Controlled Release Society. 310, p. 82-93Research output: Contribution to journal › Journal article › Research › peer-review
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Efficient Pulmonary Delivery of siRNA Using Lipid-Polymer Hybrid Nanoparticles (LPNs): Insights into Formulation, Transfection and In Vivo Biodistribution Using NIR-based Spatio-Temporal Tracking.
Thanki, K., Geyer, A., Zeng, X., Sami, H., Gehrig, S., Justesen, S., Franzyk, Henrik, Ogris, M., Nielsen, Hanne Mørck & Foged, Camilla, 2016.Research output: Contribution to conference › Poster › Research
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Preparation, Characterization, and In Vitro Evaluation of Lipidoid-Polymer Hybrid Nanoparticles for siRNA Delivery to the Cytosol
Thanki, K., Zeng, X. & Foged, Camilla, 2019, In: Methods in molecular biology (Clifton, N.J.). 1943, p. 141-152 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Formulation of RNA interference-based drugs for pulmonary delivery: challenges and opportunities
Thanki, K., Blum, K. G., Thakur, A., Rose, F. & Foged, Camilla, Oct 2018, In: Therapeutic Delivery. 9, 10, p. 731-749 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Immune Reactions in the Delivery of RNA Interference-Based Therapeutics: Mechanisms and Opportunities
Thanki, K., Falkenberg, E., Gangloff, M. & Foged, Camilla, 31 Aug 2018, Immune Effects of Biopharmaceuticals and Nanomedicine. Bawa, R., Szebeni, J. & Audette, G. (eds.). Pan Stanford, 32 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Engineering of small interfering RNA-loaded lipidoid-poly(DL-lactic-co-glycolic acid) hybrid nanoparticles for highly efficient and safe gene silencing: A quality by design-based approach
Thanki, K., Zeng, X., Justesen, S., Tejlmann, S., Falkenberg, E., Van Driessche, E., Nielsen, Hanne Mørck, Franzyk, Henrik & Foged, Camilla, Nov 2017, In: European Journal of Pharmaceutics and Biopharmaceutics. 120, p. 22-33 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Lipid-polymer hybrid nanoparticles (LPNs) for efficient pulmonary delivery of nucleic acids: Lessons learnt from quality-by-design based optimization, immunogenicity studies, in vitro release experiments, in vivo biodistribution and efficacy studies
Thanki, K., Thakur, A., de Groot, A. M., Geyer, A., Fraire, J., Falkenberg, E., Van Eygen, H., Putteman, E., Van Bijnen, D. C. J., Zeng, X., Sami, H., Gehrig, S., Justesen, S., Franzyk, H., Broere, F., van Eden, W., Sijts, A. J. A. M., Ogris, M., Nielsen, H. M., Braeckmans, K. & 1 others, , 2018.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
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Immunological and physical evaluation of the multistage tuberculosis subunit vaccine candidate H56/CAF01 formulated as a spray-dried powder
Thakur, A., Ingvarsson, P. T., Schmidt, S. T., Rose, F., Andersen, P., Christensen, D. & Foged, Camilla, 31 May 2018, In: Vaccine. 36, 23, p. 3331-3339 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Nanoparticles for mucosal vaccine delivery
Thakur, A. & Foged, Camilla, 2020, Nanoengineered Biomaterials for Advanced Drug Delivery. Mozafari, M. (ed.). 1 ed. ElsevierResearch output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Nanoparticles for mucosal vaccine delivery
Thakur, A. & Foged, Camilla, 2020, Nanoengineered Biomaterials for Advanced Drug Delivery. Woodhead Publishing, p. 603-646 44 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Method of manufacturing CAF®09 liposomes affects immune responses induced by adjuvanted subunit proteins
Thakur, A., Wadhwa, A., Lokras, Abhijeet, Amanda Oest Müllertz, O., Christensen, D., Franzyk, Henrik & Foged, Camilla, 2023, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 189, p. 84-97Research output: Contribution to journal › Journal article › Research › peer-review
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Design of gadoteridol-loaded cationic liposomal adjuvant CAF01 for MRI of lung deposition of intrapulmonary administered particles
Thakur, A., Rose, F., Ansari, S. R., Koch, P., Martini, V., Ovesen, S. L., Quistorff, B., Maritim, S., Hyder, F., Andersen, Peter, Christensen, D., Mori, Yuki & Foged, Camilla, 2019, In: Molecular Pharmaceutics. 16, 11, p. 4725-4737 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Optimizing the design and dosing of dry powder inhaler formulations of the cationic liposome adjuvant CAF®01 for pulmonary immunization
Thakur, A., Xu, Y., Cano-Garcia, G., Feng, S., Rose, F., Gerde, P., Andersen, Peter, Christensen, D. & Foged, Camilla, 2022, In: Frontiers in Drug Delivery. 2, 973599.Research output: Contribution to journal › Journal article › Research › peer-review
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Dual-Isotope SPECT/CT Imaging of the Tuberculosis Subunit Vaccine H56/CAF01: Induction of Strong Systemic and Mucosal IgA and T-Cell Responses in Mice Upon Subcutaneous Prime and Intrapulmonary Boost Immunization
Thakur, A., Rodríguez-Rodríguez, C., Saatchi, K., Rose, F., Esposito, T., Nosrati, Z., Andersen, P., Christensen, D., Häfeli, U. O. & Foged, Camilla, 2018, In: Frontiers in Immunology. 9, 21 p., 2825.Research output: Contribution to journal › Journal article › Research › peer-review
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Intrapulmonary (i.pulmon.) Pull Immunization With the Tuberculosis Subunit Vaccine Candidate H56/CAF01 After Intramuscular (i.m.) Priming Elicits a Distinct Innate Myeloid Response and Activation of Antigen-Presenting Cells Than i.m. or i.pulmon. Prime Immunization Alone
Thakur, A., Pinto, F. E., Hansen, Harald S., Andersen, Peter, Christensen, D., Janfelt, Christian & Foged, Camilla, 2020, In: Frontiers in Immunology. 11, p. 803Research output: Contribution to journal › Journal article › Research › peer-review
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MRI-assessed therapeutic effects of locally administered PLGA nanoparticles loaded with anti-inflammatory siRNA in a murine arthritis model
Te Boekhorst, B. C. M., Jensen, L. B., Colombo, S., Varkouhi, A. K., Schiffelers, R. M., Lammers, T., Storm, G., Nielsen, Hanne Mørck, Strijkers, G. J., Foged, Camilla & Nicolay, K., 2012, In: Journal of controlled release : official journal of the Controlled Release Society. 161, 3, p. 772-80 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Comparison of two different PEGylation strategies for the liposomal adjuvant CAF09: Towards induction of CTL responses upon subcutaneous vaccine administration
Tandrup Schmidt, S., Line Olsen, C., Franzyk, Henrik, Wørzner, K., Smith Korsholm, K., Rades, Thomas, Andersen, P., Foged, Camilla & Christensen, D., 2019, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 140, p. 29-39 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Systematic investigation of the role of surfactant composition and choice of oil: Design of a nanoemulsion-based adjuvant inducing concomitant humoral and CD4+ T-cell responses
Schmidt, S. T., Neustrup, M. A., Rønholt, Stine, Korsholm, K. S., Rades, Thomas, Andersen, P., Christensen, D. & Foged, Camilla, Aug 2017, In: Pharmaceutical Research. 34, 8, p. 1716-1727 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The administration route is decisive for the ability of the vaccine adjuvant CAF09 to induce antigen-specific CD8(+) T-cell responses: The immunological consequences of the biodistribution profile
Schmidt, S. T., Khadke, S., Korsholm, K. S., Perrie, Y., Rades, Thomas, Andersen, P., Foged, Camilla & Christensen, D., 26 Aug 2016, In: Journal of controlled release : official journal of the Controlled Release Society. 239, p. 107-117 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Liposome-Based Adjuvants for Subunit Vaccines: Formulation Strategies for Subunit Antigens and Immunostimulators
Schmidt, S. T., Foged, Camilla, Korsholm, K. S., Rades, Thomas & Christensen, D., 10 Mar 2016, In: Pharmaceutics. 8, 1, 22 p., 7.Research output: Contribution to journal › Review › Research › peer-review
ID: 1299454
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280
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Comparison of two different PEGylation strategies for the liposomal adjuvant CAF09: Towards induction of CTL responses upon subcutaneous vaccine administration
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
255
downloads
Opportunities and Challenges in the Delivery of mRNA-based Vaccines
Research output: Contribution to journal › Review › Research › peer-review
Published -
220
downloads
Immunogenicity Testing of Lipidoids In Vitro and In Silico: Modulating Lipidoid-Mediated TLR4 Activation by Nanoparticle Design
Research output: Contribution to journal › Journal article › Research › peer-review
Published