Birger Brodin Larsen
Professor
CNS Drug Delivery and Barrier Modelling
Universitetsparken 2
2100 København Ø
- 2016
- Published
ATP induce intracellular calcium rises in cultures of primary brain pericytes
Jensen, S. H., Helms, H. C. C., Jessen, S. B., Lauritzen, Martin, Waagepetersen, Helle S. & Larsen, Birger Brodin, Jun 2016.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
- Published
In vitro blood-brain barrier permeability predictions for GABAA receptor modulating piperine analogs
Eigenmann, D. E., Dürig, C., Jähne, E. A., Smieško, M., Culot, M., Gosselet, F., Cecchelli, R., Helms, H. C. C., Larsen, Birger Brodin, Wimmer, L., Mihovilovic, M. D., Hamburger, M. & Oufir, M., Jun 2016, In: European Journal of Pharmaceutics and Biopharmaceutics. 103, p. 118-26 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In vitro models of the blood-brain barrier: An overview of commonly used brain endothelial cell culture models and guidelines for their use
Helms, H. C. C., Abbott, N. J., Burek, M., Cecchelli, R., Couraud, P., Deli, M. A., Förster, C., Galla, H. J., Romero, I. A., Shusta, E. V., Stebbins, M. J., Vandenhaute, E., Weksler, B. & Larsen, Birger Brodin, May 2016, In: Journal of Cerebral Blood Flow and Metabolism. 36, 5, p. 862-90 29 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Functional Insulin Receptor expression does not facilitate transendothelial passage of insulin in a bovine in vitro blood-brain barrier model
Hersom, M. N. S., Helms, H. C. C., Pedersen, T., Buckley, S. & Larsen, Birger Brodin, 3 Mar 2016.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
- Published
IPEC-J2 MDR1, a Novel High-Resistance Cell Line with Functional Expression of Human P-glycoprotein (ABCB1) for Drug Screening Studies
Saaby, Lasse, Helms, H. C. C. & Larsen, Birger Brodin, 1 Feb 2016, In: Molecular Pharmaceutics. 13, 2, p. 640-52 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Stroke and Drug Delivery--In Vitro Models of the Ischemic Blood-Brain Barrier
Tornabene, E. & Larsen, Birger Brodin, Feb 2016, In: Journal of Pharmaceutical Sciences. 105, 2, p. 398-405 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
- Published
Application of Cell Culture and Tissue Models for Assessing Drug Transport
Nielsen, C. U. & Larsen, Birger Brodin, 2016, Analytical Techniques in the Pharmaceutical Sciences. Müllertz, A., Perrie, Y. & Rades, T. (eds.). Springer, p. 791-821 30 p. (Advances in Delivery Science and Technology; No. 1).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Rises in intracellular calcium in primary brain pericytes are caused by ATP
Jensen, S. H., Helms, H. C. C., Cai, Changsi, Lauritzen, Martin, Waagepetersen, Helle S. & Larsen, Birger Brodin, 2016. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
- 2015
- Published
ATP induce an increase in intracellular Ca2+ in pericytes of the blood-brain barrier
Jensen, S. H., Helms, H. C. C., Jessen, S. B., Lauritzen, Martin, Waagepetersen, Helle S. & Larsen, Birger Brodin, 2 Nov 2015.Research output: Contribution to conference › Poster › Research › peer-review
- Published
Purinergic Signaling in Pericytes of the Blood-Brain Barrier
Jensen, S. H., Helms, H. C. C., Jessen, S. B., Lauritzen, Martin, Waagepetersen, Helle S. & Larsen, Birger Brodin, Jul 2015.Research output: Contribution to conference › Poster › Research › peer-review
- Published
The putative P-gp inhibitor telmisartan does not affect the transcellular permeability and cellular uptake of the calcium channel antagonist verapamil in the P-glycoprotein expressing cell line MDCK II MDR1
Saaby, Lasse, Tfelt-Hansen, P. & Larsen, Birger Brodin, 11 Jun 2015, In: Pharmacology Research & Perspectives. 3, 4, p. 1-9 9 p., e00151.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In Vitro Blood-Brain Barrier Models-An Overview of Established Models and New Microfluidic Approaches
Wolff, A., Antfolk, M., Larsen, Birger Brodin & Tenje, M., 28 Jan 2015, In: Journal of Pharmaceutical Sciences. 104, 9, p. 2727-2746 20 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2014
- Published
Efflux transporter expression in a tight in vitro model of the blood brain barrier
Helms, H. C. C., Hersom, M. N. S., Kuhlmann, L. B., Badolo, L., Nielsen, C. U. & Larsen, Birger Brodin, 10 Dec 2014. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
- Published
Expression profiles of selected receptor systems in a bovine in vitro blood-brain barrier model
Hersom, M. N. S., Helms, H. C. C., Nielsen, M. S., Holm, R. & Larsen, Birger Brodin, 10 Dec 2014. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
- Published
Transport pathways mediating blood-to-brain L-glutamate efflux
Helms, H. C. C., Nielsen, C. U., Waagepetersen, Helle S. & Larsen, Birger Brodin, 10 Dec 2014. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
- Published
VPS10P domain receptor trafficking in brain endothelial cells
Siupka, P., Højland, A., Thomsen, L. B., Lykke-Hartmann, K., Helms, H. C. C., Larsen, Birger Brodin, Moos, T., Madsen, P. S. & Nielsen, M. S., 10 Dec 2014. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
- Published
Glutamate Efflux at the Blood-Brain Barrier: Cellular Mechanisms and Potential Clinical Relevance
Cederberg-Helms, H. C., Uhd-Nielsen, C. & Larsen, Birger Brodin, 15 Nov 2014, In: Archives of Medical Research. 45, 8, p. 639-645 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
THE POSSIBLE EFFECT OF TELMISARTAN ON THE BLOOD-BRAIN BARRIER TRANSPORT OF VERAPAMIL.
Saaby, Lasse, Tfelt-Hansen, P. & Larsen, Birger Brodin, 18 Sep 2014. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
- Published
A Tight Blood-Brain Barrier Model Displays Brain-to-Blood Efflux of Substrates for the ABC-Transporters, P-gp, BCRP and MRP-1
Helms, H. C. C., Hersom, M. N. S., Kuhlmann, L. B., Badolo, L., Nielsen, C. U. & Larsen, Birger Brodin, 11 Sep 2014. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
- Published
IN VITRO MEMBRANE PERMEATION STUDIES AND IN VIVO ANTINOCICEPTION OF GLYCOSYLATED Dmt1-DALDA ANALOGUES
Betti, C., Novoa, A., Tömböly, C., Nielsen, C. U., Helms, H. C. C., Lesniak, A., Klecskowska, P., Chung, N. N., Chung, N. N., Lipkowski, A. W., Larsen, Birger Brodin, Tourwé, D., Schiller, P. W. & Ballet, S., 31 Aug 2014. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
- Published
An Electrically Tight In Vitro Blood-Brain Barrier Model Displays Net Brain-to-Blood Efflux of Substrates for the ABC Transporters, P-gp, Bcrp and Mrp-1
Helms, H. C., Hersom, M., Kuhlmann, L. B., Badolo, L., Nielsen, C. U. & Larsen, Birger Brodin, 17 Jun 2014, In: A A P S Journal. 16, 5, p. 1046-1055 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular mechanisms underlying potassium transport in an in vitro model of the blood-brain barrier
Pedersen, K. L., Assentoft, M., Helms, H. C. C., Larsen, Birger Brodin & MacAulay, N., 12 May 2014. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
- Published
In Vitro Membrane Permeation Studies and in Vivo Antinociception of Glycosylated Dmt(1)-DALDA Analogues
Ballet, S., Betti, C., Novoa, A., Tömböly, C., Nielsen, C. U., Helms, H. C., Lesniak, A., Kleczkowska, P., Chung, N. N., Lipkowski, A. W., Larsen, Birger Brodin, Tourwé, D. & Schiller, P. W., 10 Apr 2014, In: ACS Medicinal Chemistry Letters. 5, 4, p. 352-357 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Design of prodrugs targeting the intestinal di/tri‐peptide transporter hPEPT1 (SLC15A1
Omkvist, D. H., Nielsen, C. U., Steffansen, B., Larsen, S. B., Olsen, L., Jørgensen, Flemming Steen & Larsen, Birger Brodin, 4 Apr 2014. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
ID: 1299175
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Design of prodrugs targeting the intestinal di/tri‐peptide transporter hPEPT1 (SLC15A1
Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
Published -
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A bovine in vitro blood-brain barrier model under oxygenglucose deprivation (OGD) condition
Research output: Contribution to conference › Poster › Research
Published