Holger Grohganz

Holger Grohganz

Associate Professor

ORCID: 0000-0002-0482-1397

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  1. Published

    Wet granulation of co-amorphous indomethacin systems

    Schütz, D., Timmerhaus, A. & Grohganz, Holger, 2023, In: International Journal of Pharmaceutics. 644, 9 p., 123318.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Properties of the Sodium Naproxen-Lactose-Tetrahydrate Co-Crystal upon Processing and Storage

    Sovago, I., Wang, W., Qiu, D., Raijada, D. K., Rantanen, Jukka, Grohganz, Holger, Rades, Thomas, Bond, A. D. & Löbmann, Korbinian, 2016, In: Molecules. 21, 4, p. 1-13 13 p., 509.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Compaction Behavior of Co-Amorphous Systems

    Sørensen, C. M., Rantanen, Jukka & Grohganz, Holger, 2023, In: Pharmaceutics. 15, 3, 12 p., 858.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Well-plate freeze-drying: a high throughput platform for screening of physical properties of freeze-dried formulations

    Trnka, H., Rantanen, Jukka & Grohganz, Holger, 2015, In: Pharmaceutical Development and Technology. 20, 1, p. 65-73 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Fuzzy Logic-based expert system for evaluating cake quality of freeze-dried formulations

    Trnka, H., Wu, J., van de Weert, Marco, Grohganz, Holger & Rantanen, Jukka, Dec 2013, In: Journal of Pharmaceutical Sciences. 102, 12, p. 4364-74 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Near-Infrared Imaging for High-Throughput Screening of Moisture-Induced Changes in Freeze-Dried Formulations

    Trnka, H., Palou, A., Panouillot, P. E., Kauppinen, A., Toiviainen, M., Grohganz, Holger, Alcalà, M., Juuti, M., Ketolainen, J. & Rantanen, Jukka, 24 Mar 2014, In: Journal of Pharmaceutical Sciences. 103, 9, p. 2839–2846 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Application of a Salt Coformer in a Co-Amorphous Drug System Dramatically Enhances the Glass Transition Temperature: A Case Study of the Ternary System Carbamazepine, Citric Acid, and L-Arginine

    Ueda, H., Wu, W., Löbmann, Korbinian, Grohganz, Holger, Mullertz, Anette & Rades, Thomas, May 2018, In: Molecular Pharmaceutics. 15, 5, p. 2036-2044

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Formulation of co-amorphous systems from naproxen and naproxen sodium and in situ monitoring of physicochemical state changes during dissolution testing by Raman spectroscopy

    Ueda, H., Bøtker, Johan Peter, Edinger, M., Löbmann, Korbinian, Grohganz, Holger, Mullertz, Anette , Rades, Thomas & Østergaard, Jesper, 2020, In: International Journal of Pharmaceutics. 587, 119662.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Influence of water and trehalose on α- and β-relaxation of freeze-dried lysozyme formulations

    Vallaster, B., Engelsing, F. & Grohganz, Holger, 2024, In: European Journal of Pharmaceutics and Biopharmaceutics. 194, p. 1-8

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Large-scale biophysical evaluation of protein PEGylation effects: in vitro properties of 61 protein entities

    Vernet, E., Popa, G., Pozdnyakova, I., Rasmussen, J. E., Grohganz, Holger, Giehm, L., Jensen, M. H., Wang, H., Plesner, B., Nielsen, Hanne Mørck, Jensen, Knud Jørgen, Berthelsen, J., Sundström, M. & van de Weert, Marco, 2016, In: Molecular Pharmaceutics. 13, 5, p. 1587-1598 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Probing Pharmaceutical Mixtures during Milling: The Potency of Low-Frequency Raman Spectroscopy in Identifying Disorder

    Walker, G., Römann, P., Poller, B., Löbmann, Korbinian, Grohganz, Holger, Rooney, J. S., Huff, G. S., Smith, G. P. S., Rades, Thomas, Gordon, K. C., Strachan, C. J. & Fraser-Miller, S. J., 2017, In: Molecular Pharmaceutics. 14, 12, p. 4675-4684 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Effects of polymer addition on the non-strongly interacting binary co-amorphous system carvedilol-tryptophan

    Wang, Y., Grohganz, Holger & Rades, Thomas, 2022, In: International Journal of Pharmaceutics. 617, 9 p., 121625.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Considerations on the Kinetic Processes in the Preparation of Ternary Co-Amorphous Systems by Milling

    Wang, Y., Rades, Thomas & Grohganz, Holger, 2023, In: Pharmaceutics. 15, 1, 14 p., 172.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Preparation of Co-Amorphous Systems by Freeze-Drying

    Wostry, M., Plappert, H. & Grohganz, Holger, 2020, In: Pharmaceutics. 12, 10, 12 p., 941.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Organic acids as co-formers for co-amorphous systems - Influence of variation in molar ratio on the physicochemical properties of the co-amorphous systems

    Wu, W., Ueda, H., Lobmann, K., Rades, Thomas & Grohganz, Holger, Oct 2018, In: European Journal of Pharmaceutics and Biopharmaceutics. 131, p. 25-32

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Transformations between Co-Amorphous and Co-Crystal Systems and Their Influence on the Formation and Physical Stability of Co-Amorphous Systems

    Wu, W., Wang, Y., Löbmann, Korbinian, Grohganz, Holger & Rades, Thomas, 4 Mar 2019, In: Molecular Pharmaceutics. 16, 3, p. 1294-1304 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Dipeptides as co-formers in co-amorphous systems

    Wu, W., Löbmann, Korbinian, Schnitzkewitz, J., Knuhtsen, A., Pedersen, D. S., Rades, Thomas & Grohganz, Holger, 1 Jan 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 134, p. 68-76 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Aspartame as a co-former in co-amorphous systems

    Wu, W., Löbmann, Korbinian, Schnitzkewitz, J., Knuhtsen, A., Pedersen, D. S., Grohganz, Holger & Rades, Thomas, 5 Oct 2018, In: International Journal of Pharmaceutics. 549, 1-2, p. 380-387

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Comparison of co-former performance in co-amorphous formulations: Single amino acids, amino acid physical mixtures, amino acid salts and dipeptides as co-formers

    Wu, W., Grohganz, Holger, Rades, Thomas & Löbmann, Korbinian, 2021, In: European Journal of Pharmaceutical Sciences. 156, 8 p., 105582.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    On the role of salt formation and structural similarity of co-formers in co-amorphous drug delivery systems

    Wu, W., Löbmann, Korbinian, Rades, Thomas & Grohganz, Holger, 15 Jan 2018, In: International Journal of Pharmaceutics. 535, 1-2, p. 86-94

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Influence of Water on Amorphous Lidocaine

    Xu, X., Grohganz, Holger & Rades, Thomas, 2022, In: Molecular Pharmaceutics. 19, 9, p. 3199–3205

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Molecular interactions of hydrated co-amorphous systems of prilocaine and lidocaine

    Xu, X., Rades, Thomas & Grohganz, Holger, 2024, In: International Journal of Pharmaceutics. 651, 7 p., 123807.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Anti-plasticizing effect of water on prilocaine and lidocaine: the role of the hydrogen bonding pattern

    Xu, X., Grohganz, Holger & Rades, Thomas, 2024, In: Physical Chemistry Chemical Physics. 26, p. 14149-14159

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Thermal investigation on hydrated co-amorphous systems of nicotinamide and prilocaine

    Xu, X., Rades, Thomas & Grohganz, Holger, 2023, In: European Journal of Pharmaceutics and Biopharmaceutics. 186, p. 1-6

    Research output: Contribution to journal › Journal article › Research › peer-review

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