Vaccine Design and Delivery

  1. 2018
  2. Published

    Effects of Aggregate Charge and Subphase Ionic Strength on the Properties of Spread Polyelectrolyte/Surfactant Films at the Air/Water Interface under Static and Dynamic Conditions

    Tummino, A., Toscano, J., Sebastiani, Federica, Noskov, B. A., Varga, I. & Campbell, R. A., 13 Feb 2018, In: Langmuir. 34, 6, p. 2312-2323 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    A strong adjuvant based on glycol-chitosan-coated lipid-polymer hybrid nanoparticles potentiates mucosal immune responses against the recombinant Chlamydia trachomatis fusion antigen CTH522

    Rose, F., Erbo Wern, J., Gavins, F., Andersen, P., Follmann, F. & Foged, Camilla, Feb 2018, In: Journal of Controlled Release. 271, p. 88-97 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Submitted
  5. Published

    Dual-Isotope SPECT/CT Imaging of the Tuberculosis Subunit Vaccine H56/CAF01: Induction of Strong Systemic and Mucosal IgA and T-Cell Responses in Mice Upon Subcutaneous Prime and Intrapulmonary Boost Immunization

    Thakur, A., Rodríguez-Rodríguez, C., Saatchi, K., Rose, F., Esposito, T., Nosrati, Z., Andersen, P., Christensen, D., Häfeli, U. O. & Foged, Camilla, 2018, In: Frontiers in Immunology. 9, 21 p., 2825.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Insight into Nanoscale Network of Spray-dried Polymeric Particles: Role of Polymer Molecular Conformation

    Wan, F., Larsen, F. H., Nunes Bordallo, Heloisa, Foged, Camilla, Rantanen, Jukka & Yang, Mingshi, 2018, In: A C S Applied Materials and Interfaces. 10, 43, p. 36686-36692

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Lipid-polymer hybrid nanoparticles (LPNs) for efficient pulmonary delivery of nucleic acids: Lessons learnt from quality-by-design based optimization, immunogenicity studies, in vitro release experiments, in vivo biodistribution and efficacy studies

    Thanki, K., Thakur, A., de Groot, A. M., Geyer, A., Fraire, J., Falkenberg, E., Van Eygen, H., Putteman, E., Van Bijnen, D. C. J., Zeng, X., Sami, H., Gehrig, S., Justesen, S., Franzyk, H., Broere, F., van Eden, W., Sijts, A. J. A. M., Ogris, M., Nielsen, H. M., Braeckmans, K. & 1 others, Foged, Camilla, 2018.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  8. Published

    Mechanisms of deformable nanovesicles based on insulin-phospholipid complex for enhancing buccal delivery of insulin

    Xu, You, Zhang, X., Zhang, Y., Ye, J., Wang, H., Xia, X. & Liu, Y., 2018, In: International Journal of Nanomedicine. 13, p. 7319-7331 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Potential mucus rheological consequences of off target siRNA loaded nanoparticle deposition in the lungs

    Katuwal, N., Loretz, B., Thanki, K., Hallbrink, M., Lehr, C., Foged, Camilla, Draget, K. & Nordgård, C. T., 2018, ANNUAL TRANSACTIONS OF THE NORDIC RHEOLOGY SOCIETY. Vol. 26.

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearch

  10. Published

    Selected contributions from the 10th European Workshop on Particulate Systems, Copenhagen 19th–20th January 2017

    Foged, Camilla, 2018, In: International Journal of Pharmaceutics. 548, 2, p. 729

    Research output: Contribution to journalEditorialResearch

  11. Published

    Temperature-Induced Self-Assembly of the Group B Streptococcus (GBS) Fusion Antigen GBS-NN

    Rose, F., Roovers, S., Fano, M., Rønholt, Stine, Kirkensgaard, Jacob Judas Kain, Hejnaes, K., Fischer, P. & Foged, Camilla, 2018, In: Molecular Pharmaceutics. 15, p. 2584-2593 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. 2017
  13. Published

    Inhalable siRNA-loaded nano-embedded microparticles engineered using microfluidics and spray drying

    Agnoletti, M., Bohr, A., Thanki, K., Wan, F., Zeng, X., Bøtker, Johan Peter, Yang, Mingshi & Foged, Camilla, Nov 2017, In: European Journal of Pharmaceutics and Biopharmaceutics. 120, p. 9-21

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Adjuvants based on synthetic mycobacterial cord factor analogues: Biophysical properties of neat glycolipids and nano-self-assemblies with DDA

    Kallerup, R. S., Franzyk, Henrik, Schiøth, M. L., Justesen, S., Martin-Bertelsen, Birte, Rose, F., Madsen, C. M., Christensen, D., Korsholm, K. S., Yaghmur, Anan & Foged, Camilla, 12 May 2017, In: Molecular Pharmaceutics. 14, 7, p. 2294-2306 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Structural Analysis of Multi-component Amyloid Systems by Chemometric SAXS Data Decomposition

    Trillo, I. F. H., Jensen, M. G., van Maarschalkerweerd, A., Tauler, R., Vestergaard, Bente & Bernadó, P., 3 Jan 2017, In: Structure. 25, 1, p. 5–15 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Efficient Pulmonary Delivery of siRNA Using Lipid-polymer Hybrid Nanoparticles (LPNs): A quality-by-design approach for highly systematic optimization of LPNs

    Thanki, K., Zeng, X., Justesen, S., Tejlmann, S., Falkenberg, E., Nielsen, Hanne Mørck, Franzyk, Henrik & Foged, Camilla, 2017.

    Research output: Contribution to conferencePosterResearch

  17. Published
  18. Published

    Simultaneous neutron reflectometry and infrared reflection absorption spectroscopy (IRRAS) study of mixed monolayer reactions at the air-water interface

    Skoda, M. W. A., Thomas, B., Hagreen, M., Sebastiani, Federica & Pfrang, C., 2017, In: RSC Advances.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Synthesis and Characterisation of an Array of Lipidoid Analogues for RNA Interference Therapy

    Falkenberg, E., de Groot, A. M., Sijts, A. J. A. M., Thanki, K., Zeng, X., Nielsen, Hanne Mørck, Franzyk, Henrik & Foged, Camilla, 2017.

    Research output: Contribution to conferencePosterResearch

  20. 2016
  21. Published

    Conserved molecular superlattices in a series of homologous synthetic mycobacterial cell-wall lipids forming interdigitated bilayers

    Martin-Bertelsen, Birte, Yaghmur, Anan, Franzyk, Henrik, Justesen, S., Kirkensgaard, Jacob Judas Kain & Foged, Camilla, 7 Nov 2016, In: Langmuir. 32, 48, p. 12693–12701 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    The administration route is decisive for the ability of the vaccine adjuvant CAF09 to induce antigen-specific CD8(+) T-cell responses: The immunological consequences of the biodistribution profile

    Schmidt, S. T., Khadke, S., Korsholm, K. S., Perrie, Y., Rades, Thomas, Andersen, P., Foged, Camilla & Christensen, D., 26 Aug 2016, In: Journal of controlled release : official journal of the Controlled Release Society. 239, p. 107-117 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Trehalose diester glycolipids are superior to the monoesters in binding to Mincle, activation of macrophages invitro and adjuvant activity invivo

    Huber, A., Kallerup, R. S., Korsholm, K. S., Franzyk, Henrik, Lepenies, B., Christensen, D., Foged, Camilla & Lang, R., Aug 2016, In: Innate Immunity. 22, 6, p. 405-418 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Delivery of siRNA Complexed with Palmitoylated α-Peptide/β-Peptoid Cell-Penetrating Peptidomimetics: Membrane Interaction and Structural Characterization of a Lipid-Based Nanocarrier System.

    Jing, X., Foged, Camilla, Martin-Bertelsen, Birte, Yaghmur, Anan, Knapp, K. M., Malmsten, M., Franzyk, Henrik & Nielsen, Hanne Mørck, 6 Jun 2016, In: Molecular Pharmaceutics. 13, 6, p. 1739-1749 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Liposome-Based Adjuvants for Subunit Vaccines: Formulation Strategies for Subunit Antigens and Immunostimulators

    Schmidt, S. T., Foged, Camilla, Korsholm, K. S., Rades, Thomas & Christensen, D., 10 Mar 2016, In: Pharmaceutics. 8, 1, 22 p., 7.

    Research output: Contribution to journalReviewResearchpeer-review

  26. Published

    Nano-self-assemblies based on synthetic analogues of mycobacterial monomycoloyl glycerol and DDA: Supramolecular structure and adjuvant efficacy

    Martin-Bertelsen, Birte, Korsholm, K. S., Christensen, D., Franzyk, Henrik, Yaghmur, Anan & Foged, Camilla, 2016, In: Molecular Pharmaceutics. 13, 8, p. 2771-2781 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Thermostable Subunit Vaccines for Pulmonary Delivery: How Close Are We?

    Foged, Camilla, 2016, In: Current Pharmaceutical Design. 22, 17, p. 2561-2576 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. 2015
  29. Published

    Intracellular siRNA delivery dynamics of integrin-targeted, PEGylated chitosan-poly(ethylene imine) hybrid nanoparticles: A mechanistic insight

    Ragelle, H., Colombo, S., Pourcelle, V., Vanvarenberg, K., Vandermeulen, G., Bouzin, C., Marchand-Brynaert, J., Feron, O., Foged, Camilla & Préat, V., 10 Aug 2015, In: Journal of Controlled Release. 211, p. 1-9 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review