Vaccine Design and Delivery

  1. Published

    Effect of lipid-polymer hybrid nanoparticles on the biophysical function and lateral structure of pulmonary surfactant: Mechanistic in vitro studies

    Xu, Y., Cañadas, O., Alonso, A., Franzyk, Henrik, Thakur, A., Pérez-gil, J. & Foged, Camilla, 2024, In: Journal of Colloid and Interface Science. 654, Part B, p. 1111-1123

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Effects of Aggregate Charge and Subphase Ionic Strength on the Properties of Spread Polyelectrolyte/Surfactant Films at the Air/Water Interface under Static and Dynamic Conditions

    Tummino, A., Toscano, J., Sebastiani, Federica, Noskov, B. A., Varga, I. & Campbell, R. A., 13 Feb 2018, In: Langmuir. 34, 6, p. 2312-2323 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Efficient Pulmonary Delivery of siRNA Using Lipid-polymer Hybrid Nanoparticles (LPNs): A quality-by-design approach for highly systematic optimization of LPNs

    Thanki, K., Zeng, X., Justesen, S., Tejlmann, S., Falkenberg, E., Nielsen, Hanne Mørck, Franzyk, Henrik & Foged, Camilla, 2017.

    Research output: Contribution to conferencePosterResearch

  4. Published

    Elucidating the nanostructure of small interfering RNA-loaded lipidoid-polymer hybrid nanoparticles

    Aljabbari, Anas Samir Mohammad, Lokras, Abhijeet, Kirkensgaard, Jacob Judas Kain, Rades, Thomas, Franzyk, Henrik, Thakur, A., Zhang, Y. & Foged, Camilla, 2023, In: Journal of Colloid and Interface Science. 633, p. 907-922

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Engineering aspects of lipid-based delivery systems: In vivo gene delivery, safety criteria, and translation strategies

    Eş, I., Thakur, A., Mousavi Khaneghah, A., Foged, Camilla & de la Torre, L. G., 2024, In: Biotechnology Advances. 72, 45 p., 108342.

    Research output: Contribution to journalReviewResearchpeer-review

  6. Published

    Engineering of Solid Dosage Forms of siRNA-Loaded Lipidoid-Polymer Hybrid Nanoparticles Using a Quality-by-Design Approach

    Lokras, Abhijeet, Foged, Camilla & Thakur, A., 2021, Design and Delivery of SiRNA Therapeutics. Ditzel, H. J., Tuttolomondo, M. & Kauppinen, S. (eds.). Humana Press, p. 137-157 (Methods in Molecular Biology, Vol. 2282).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  7. Published

    Engineering of a novel adjuvant based on lipid-polymer hybrid nanoparticles: A quality-by-design approach

    Rose, F., Wern, J. E., Ingvarsson, P. T., van de Weert, Marco, Andersen, P., Follmann, F. & Foged, Camilla, 2015, In: Journal of controlled release : official journal of the Controlled Release Society. 210, p. 48-57 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Engineering of budesonide-loaded lipid-polymer hybrid nanoparticles using a quality-by-design approach

    Leng, D., Thanki, K., Fattal, E., Foged, Camilla & Yang, Mingshi, 15 Sep 2018, In: International Journal of Pharmaceutics. 548, 2, p. 740-746

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Enhanced antitumor efficacy and counterfeited cardiotoxicity of combinatorial oral therapy using Doxorubicin- and Coenzyme Q10-liquid crystalline nanoparticles in comparison with intravenous Adriamycin

    Swarnakar, N. K., Thanki, K. & Jain, S., Aug 2014, In: Nanomedicine: Nanotechnology, Biology and Medicine. 10, 6, p. 1231-41 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Epidemiological and clinical characteristics of 2019 novel coronavirus disease (COVID-19) in Jilin, China A descriptive study

    Liu, H., Gao, J., Wang, Y., Jie, J., Luo, J., Xu, Y., Sun, H., Song, L., Li, D., Peng, L. & Hua, S., 2020, In: Medicine. 99, 47, 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Evolution of the structure of lipid nanoparticles for nucleic acid delivery: From in situ studies of formulation to colloidal stability

    Gilbert, J., Sebastiani, Federica, Arteta, M. Y., Terry, A., Fornell, A., Russell, R., Mahmoudi, N. & Nylander, T., 2024, In: Journal of Colloid and Interface Science. 660, p. 66-76

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Folate receptor-targeted mixed polysialic acid micelles for combating rheumatoid arthritis: in vitro and in vivo evaluation

    Zhang, N., Xu, C., Li, N., Zhang, S., Fu, L., Chu, X., Hua, H., Zeng, X. & Zhao, Y., 23 May 2018, In: Drug Delivery. 25, 1, p. 1182-1191

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Formulating Inhalable Dry Powders Using Two-Fluid and Three-Fluid Nozzle Spray Drying

    Leng, D., Thanki, K., Foged, Camilla & Yang, Mingshi, 1 Nov 2018, In: Pharmaceutical Research. 35, 12, 12 p., 247.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Formulation of RNA interference-based drugs for pulmonary delivery: challenges and opportunities

    Thanki, K., Blum, K. G., Thakur, A., Rose, F. & Foged, Camilla, Oct 2018, In: Therapeutic Delivery. 9, 10, p. 731-749 19 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Grand Challenges in Vaccine Delivery: Lessons Learned From the COVID-19 Vaccine Rollout

    Foged, Camilla, 2022, In: Frontiers in Drug Delivery. 2, 4 p., 964298.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Identification of Factors of Importance for Spray Drying of Small Interfering RNA-Loaded Lipidoid-Polymer Hybrid Nanoparticles for Inhalation

    Dormenval, C., Lokras, Abhijeet, Cano-Garcia, G., Wadhwa, A., Thanki, K., Rose, F., Thakur, A., Franzyk, Henrik & Foged, Camilla, 2019, In: Pharmaceutical Research. 36, 10, 142.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Identification of p38α MAP kinase inhibitors by pharmacophore based virtual screening

    Gangwal, R. P., Das, N. R., Thanki, K., Damre, M. V., Dhoke, G. V., Sharma, S. S., Jain, S. & Sangamwar, A. T., Apr 2014, In: Journal of Molecular Graphics and Modelling. 49, p. 18-24 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Immune Reactions in the Delivery of RNA Interference-Based Therapeutics: Mechanisms and Opportunities

    Thanki, K., Falkenberg, E., Gangloff, M. & Foged, Camilla, 31 Aug 2018, Immune Effects of Biopharmaceuticals and Nanomedicine. Bawa, R., Szebeni, J. & Audette, G. (eds.). Pan Stanford, 32 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  19. Published

    Immune responses induced by nano-self-assembled lipid adjuvants based on a monomycoloyl glycerol analogue after vaccination with the Chlamydia trachomatis major outer membrane protein

    Rodrigues, L., Raftopoulos, K. N., Tandrup Schmidt, S., Schneider, F., Dietz, H., Rades, Thomas, Franzyk, Henrik, Pedersen, Anders Elm, Papadakis, C. M., Christensen, D., Winter, G., Foged, Camilla & Hubert, M., 10 Sep 2018, In: Journal of controlled release : official journal of the Controlled Release Society. 285, p. 12-22 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Immunogenicity Testing of Lipidoids In Vitro and In Silico: Modulating Lipidoid-Mediated TLR4 Activation by Nanoparticle Design

    de Groot, A. M., Thanki, K., Gangloff, M., Falkenberg, E., Zeng, X., van Bijnen, D. C. J., van Eden, W., Franzyk, Henrik, Nielsen, Hanne Mørck, Broere, F., Gay, N. J., Foged, Camilla & Sijts, A. J. A. M., 1 Jun 2018, In: Molecular Therapy - Nucleic Acids. 11, p. 159-169 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Immunological and physical evaluation of the multistage tuberculosis subunit vaccine candidate H56/CAF01 formulated as a spray-dried powder

    Thakur, A., Ingvarsson, P. T., Schmidt, S. T., Rose, F., Andersen, P., Christensen, D. & Foged, Camilla, 31 May 2018, In: Vaccine. 36, 23, p. 3331-3339 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Improved insulin loading in poly (lactic-co-glycolic) acid (PLGA) nanoparticles upon self-assembly with lipids

    Garcia Diaz, M., Foged, Camilla & Nielsen, Hanne Mørck, 2015, In: International Journal of Pharmaceutics. 482, p. 84-91 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Improved stability and antidiabetic potential of insulin containing folic acid functionalized polymer stabilized multilayered liposomes following oral administration

    Agrawal, A. K., Harde, H., Thanki, K. & Jain, S., 13 Jan 2014, In: Biomacromolecules. 15, 1, p. 350-60 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Induction of CD8+ T-cell responses against subunit antigens by the novel cationic liposomal CAF09 adjuvant

    Korsholm, K. S., Hansen, J., Karlsen, K., Filskov, J., Mikkelsen, M., Lindenstrøm, T., Schmidt, S. T., Andersen, P. & Christensen, D., 30 Jun 2014, In: Vaccine. 32, 31, p. 3927-35 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Induction of Cytotoxic T-Lymphocyte Responses Upon Subcutaneous Administration of a Subunit Vaccine Adjuvanted With an Emulsion Containing the Toll-Like Receptor 3 Ligand Poly(I:C)

    Schmidt, S. T., Pedersen, G. K., Neustrup, M. A., Korsholm, K. S., Rades, Thomas, Andersen, P., Foged, Camilla & Christensen, D., 30 Apr 2018, In: Frontiers in Immunology. 9, 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review