Vaccine Design and Delivery

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  1. Published

    A bifunctional enzyme of Legionella that distinctly regulates phosphoribosyl ubiquitination of the SidE family effectors

    Jiao, J., Ouyang, X., Xu, Y. & Xiong, X., 2022, In: Journal of Translational Internal Medicine. 10, 2, p. 86-88

    Research output: Contribution to journal › Editorial › Research › peer-review

  2. Published

    A stable nanoparticulate DDA/MMG formulation acts synergistically with CpG ODN 1826 to enhance the CD4(+) T-cell response

    Karlsen, K., Korsholm, K. S., Mortensen, R., Ghiasi, S. M., Andersen, P., Foged, Camilla & Christensen, D., Dec 2014, In: Nanomedicine. 9, 17, p. 2625-38 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    A strong adjuvant based on glycol-chitosan-coated lipid-polymer hybrid nanoparticles potentiates mucosal immune responses against the recombinant Chlamydia trachomatis fusion antigen CTH522

    Rose, F., Erbo Wern, J., Gavins, F., Andersen, P., Follmann, F. & Foged, Camilla, Feb 2018, In: Journal of Controlled Release. 271, p. 88-97 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    A study on the prevalence of bovine tuberculosis in farmed dairy cattle in Himachal Pradesh

    Thakur, A., Sharma, M., Katoch, V. C., Dhar, P. & Katoch, R. C., 1 Dec 2010, In: Veterinary World. 3, 9, p. 408-414 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Adjuvants based on synthetic mycobacterial cord factor analogues: Biophysical properties of neat glycolipids and nano-self-assemblies with DDA

    Kallerup, R. S., Franzyk, Henrik, Schiøth, M. L., Justesen, S., Martin-Bertelsen, Birte, Rose, F., Madsen, C. M., Christensen, D., Korsholm, K. S., Yaghmur, Anan & Foged, Camilla, 12 May 2017, In: Molecular Pharmaceutics. 14, 7, p. 2294-2306 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Adjuvants, immunomodulators, and adaptogens

    Milicic, A., Reinke, S., Fergusson, J., Lindblad, E. B., Hu, K., Thakur, A., Corby, G., Longet, S., Górska, S., Razim, A., Morein, B., Luchner, M., Christensen, D., Mrenoshki, S., Ceylan, S. E., Gizurarson, S. & Ugwu, M. C., 2022, Vaccinology and Methods in Vaccine Research. Elsevier, p. 223-280

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  7. Published

    Adsorption of protein antigen to the cationic liposome adjuvant CAF®01 is required for induction of Th1 and Th17 responses but not for antibody induction

    Wørzner, K., Hvannastein, J., Tandrup Schmidt, S., Foged, Camilla, Rosenkrands, I., Kristian Pedersen, G. & Christensen, D., 2021, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 165, p. 293-305

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Submitted

    Anchoring of hydrophilic coating polymers onto charged liposomes via attractive electrostatic interactions using charged tags to control the surface charge drainage properties and cellular targeting

    Andersen, P. L., Christensen, D., Franzyk, Henrik, Foged, Camilla & Schmidt, S. T., 2018, (Submitted)

    Research output: Patent

  9. Published

    Application of a Quality-By-Design Approach to Optimise Lipid-Polymer Hybrid Nanoparticles Loaded with a Splice-Correction Antisense Oligonucleotide: Maximising Loading and Intracellular Delivery

    Thanki, K., Papai, S., Lokras, Abhijeet, Rose, F., Falkenberg, E., Franzyk, Henrik & Foged, Camilla, 2019, In: Pharmaceutical Research. 36, 3, 37.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Bicontinuous cubic liquid crystalline nanoparticles for oral delivery of Doxorubicin: implications on bioavailability, therapeutic efficacy, and cardiotoxicity

    Swarnakar, N. K., Thanki, K. & Jain, S., May 2014, In: Pharmaceutical Research. 31, 5, p. 1219-38 20 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    CAF01 liposomes as a mucosal vaccine adjuvant: In vitro and in vivo investigations

    Christensen, D., Foged, Camilla, Rosenkrands, I., Lundberg, C. V., Andersen, P., Agger, E. M. & Nielsen, Hanne Mørck, 2010, In: Internation Journal of Pharmaceutics. 390, p. 19-24

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    COVID-19: Hvem skal nu vaccineres og hvorfor? Professor giver overblikket: Hvor godt virker vaccinerne? Hvem har især gavn af dem? Og hvad ved vi om bivirkningerne? Professor i vaccinedesign guider dig.

    Foged, Camilla, 16 Sep 2022, In: ForskerZonen. 16.09.2022

    Research output: Contribution to journal › Journal article › Research

  13. Published

    COVID-19: Hvordan sikrer vi, at vores vacciner virker mod de nyeste varianter? Når virus muterer, må vi tilpasse vores vacciner. Hvordan sker det i praksis? Og behøver en vaccine overhovedet være tilpasset den seneste variant for at virke?

    Foged, Camilla, 19 Sep 2022, In: ForskerZonen. 19.09.2022

    Research output: Contribution to journal › Journal article › Communication

  14. Published

    Classification of vaccines

    Kallerup, R. S. & Foged, Camilla, 2015, Subunit vaccine delivery. Foged, C., Rades, T., Perrie, Y. & Hooks, S. (eds.). Springer, p. 15-29 15 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  15. Published

    Comparative study of lipid nanoparticle-based mRNA vaccine bioprocess with machine learning and combinatorial artificial neural network-design of experiment approach

    Maharjan, R., Hada, S., Eun Lee, J., Han, H., Hyun Kim, K., Jin Seo, H., Foged, Camilla & Hoon Jeong, S., 2023, In: International Journal of Pharmaceutics. 640, 13 p., 123012.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Complementarity of neutron reflectometry and ellipsometry for the study of atmospheric reactions at the air–water interface

    Sebastiani, Federica, Campbell, R. A. & Pfrang, C., 2015, In: RSC Adv..

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Complexity in the therapeutic delivery of RNAi medicines: an analytical challenge

    Colombo, S., Zeng, X., Ragelle, H. & Foged, Camilla, Sep 2014, In: Expert Opinion on Drug Delivery. 11, 9, p. 1481-95 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Conserved molecular superlattices in a series of homologous synthetic mycobacterial cell-wall lipids forming interdigitated bilayers

    Martin-Bertelsen, Birte, Yaghmur, Anan, Franzyk, Henrik, Justesen, S., Kirkensgaard, Jacob Judas Kain & Foged, Camilla, 7 Nov 2016, In: Langmuir. 32, 48, p. 12693–12701 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Delivery of oligonucleotide-based therapeutics: challenges and opportunities

    Hammond, S. M., Aartsma-Rus, A., Alves, S., Borgos, S. E., Buijsen, R. A. M., Collin, R. W. J., Covello, G., Denti, M. A., Desviat, L. R., Echevarría, L., Foged, C., Gaina, G., Garanto, A., Goyenvalle, A. T., Guzowska, M., Holodnuka, I., Jones, D. R., Krause, S., Lehto, T., Montolio, M. & 2 others, Van Roon-Mom, W. & Arechavala-Gomeza, V., 2021, In: EMBO Molecular Medicine. 13, 4, 23 p., e13243.

    Research output: Contribution to journal › Review › Research › peer-review

  20. Published

    Delivery of siRNA Complexed with Palmitoylated α-Peptide/β-Peptoid Cell-Penetrating Peptidomimetics: Membrane Interaction and Structural Characterization of a Lipid-Based Nanocarrier System.

    Jing, X., Foged, Camilla, Martin-Bertelsen, Birte, Yaghmur, Anan, Knapp, K. M., Malmsten, M., Franzyk, Henrik & Nielsen, Hanne Mørck, 6 Jun 2016, In: Molecular Pharmaceutics. 13, 6, p. 1739-1749 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Design and evaluation of microemulsion-based efinaconazole formulations for targeted treatment of onychomycosis through transungual route: Ex vivo and nail clipping studies

    Agrawal, V., Patel, R., Patel, M., Thanki, K. & Mishra, S., 2021, In: Colloids and Surfaces B: Biointerfaces. 201, 9 p., 111652.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Design of Inhalable Solid Dosage Forms of Budesonide and Theophylline for Pulmonary Combination Therapy

    Leng, D., Kissi, E. O., Löbmann, Korbinian, Thanki, K., Fattal, E., Rades, Thomas, Foged, Camilla & Yang, Mingshi, 7 Mar 2019, In: AAPS PharmSciTech. 20, 3, 137.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Design of gadoteridol-loaded cationic liposomal adjuvant CAF01 for MRI of lung deposition of intrapulmonary administered particles

    Thakur, A., Rose, F., Ansari, S. R., Koch, P., Martini, V., Ovesen, S. L., Quistorff, B., Maritim, S., Hyder, F., Andersen, Peter, Christensen, D., Mori, Yuki & Foged, Camilla, 2019, In: Molecular Pharmaceutics. 16, 11, p. 4725-4737 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Diffraction studies on natural and model lipid bilayers

    Sebastiani, Federica, Harvey, R., Khanniche, S., Artero, J. B., Haertlein, M. & Fragneto, G., 2012, In: European physical journal-Special topics.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Dual-Isotope SPECT/CT Imaging of the Tuberculosis Subunit Vaccine H56/CAF01: Induction of Strong Systemic and Mucosal IgA and T-Cell Responses in Mice Upon Subcutaneous Prime and Intrapulmonary Boost Immunization

    Thakur, A., Rodríguez-Rodríguez, C., Saatchi, K., Rose, F., Esposito, T., Nosrati, Z., Andersen, P., Christensen, D., Häfeli, U. O. & Foged, Camilla, 2018, In: Frontiers in Immunology. 9, 21 p., 2825.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Effect of lipid-polymer hybrid nanoparticles on the biophysical function and lateral structure of pulmonary surfactant: Mechanistic in vitro studies

    Xu, Y., Cañadas, O., Alonso, A., Franzyk, Henrik, Thakur, A., Pérez-gil, J. & Foged, Camilla, 2024, In: Journal of Colloid and Interface Science. 654, Part B, p. 1111-1123

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Effects of Aggregate Charge and Subphase Ionic Strength on the Properties of Spread Polyelectrolyte/Surfactant Films at the Air/Water Interface under Static and Dynamic Conditions

    Tummino, A., Toscano, J., Sebastiani, Federica, Noskov, B. A., Varga, I. & Campbell, R. A., 13 Feb 2018, In: Langmuir. 34, 6, p. 2312-2323 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Efficient Pulmonary Delivery of siRNA Using Lipid-polymer Hybrid Nanoparticles (LPNs): A quality-by-design approach for highly systematic optimization of LPNs

    Thanki, K., Zeng, X., Justesen, S., Tejlmann, S., Falkenberg, E., Nielsen, Hanne Mørck, Franzyk, Henrik & Foged, Camilla, 2017.

    Research output: Contribution to conference › Poster › Research

  29. Published

    Elucidating the nanostructure of small interfering RNA-loaded lipidoid-polymer hybrid nanoparticles

    Aljabbari, Anas Samir Mohammad, Lokras, Abhijeet, Kirkensgaard, Jacob Judas Kain, Rades, Thomas, Franzyk, Henrik, Thakur, A., Zhang, Y. & Foged, Camilla, 2023, In: Journal of Colloid and Interface Science. 633, p. 907-922

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Engineering aspects of lipid-based delivery systems: In vivo gene delivery, safety criteria, and translation strategies

    Eş, I., Thakur, A., Mousavi Khaneghah, A., Foged, Camilla & de la Torre, L. G., 2024, In: Biotechnology Advances. 72, 45 p., 108342.

    Research output: Contribution to journal › Review › Research › peer-review

  31. Published

    Engineering of Solid Dosage Forms of siRNA-Loaded Lipidoid-Polymer Hybrid Nanoparticles Using a Quality-by-Design Approach

    Lokras, Abhijeet, Foged, Camilla & Thakur, A., 2021, Design and Delivery of SiRNA Therapeutics. Ditzel, H. J., Tuttolomondo, M. & Kauppinen, S. (eds.). Humana Press, p. 137-157 (Methods in Molecular Biology, Vol. 2282).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  32. Published

    Engineering of a novel adjuvant based on lipid-polymer hybrid nanoparticles: A quality-by-design approach

    Rose, F., Wern, J. E., Ingvarsson, P. T., van de Weert, Marco, Andersen, P., Follmann, F. & Foged, Camilla, 2015, In: Journal of controlled release : official journal of the Controlled Release Society. 210, p. 48-57 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Engineering of budesonide-loaded lipid-polymer hybrid nanoparticles using a quality-by-design approach

    Leng, D., Thanki, K., Fattal, E., Foged, Camilla & Yang, Mingshi, 15 Sep 2018, In: International Journal of Pharmaceutics. 548, 2, p. 740-746

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Enhanced antitumor efficacy and counterfeited cardiotoxicity of combinatorial oral therapy using Doxorubicin- and Coenzyme Q10-liquid crystalline nanoparticles in comparison with intravenous Adriamycin

    Swarnakar, N. K., Thanki, K. & Jain, S., Aug 2014, In: Nanomedicine: Nanotechnology, Biology and Medicine. 10, 6, p. 1231-41 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Epidemiological and clinical characteristics of 2019 novel coronavirus disease (COVID-19) in Jilin, China A descriptive study

    Liu, H., Gao, J., Wang, Y., Jie, J., Luo, J., Xu, Y., Sun, H., Song, L., Li, D., Peng, L. & Hua, S., 2020, In: Medicine. 99, 47, 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Evolution of the structure of lipid nanoparticles for nucleic acid delivery: From in situ studies of formulation to colloidal stability

    Gilbert, J., Sebastiani, Federica, Arteta, M. Y., Terry, A., Fornell, A., Russell, R., Mahmoudi, N. & Nylander, T., 2024, In: Journal of Colloid and Interface Science. 660, p. 66-76

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Folate receptor-targeted mixed polysialic acid micelles for combating rheumatoid arthritis: in vitro and in vivo evaluation

    Zhang, N., Xu, C., Li, N., Zhang, S., Fu, L., Chu, X., Hua, H., Zeng, X. & Zhao, Y., 23 May 2018, In: Drug Delivery. 25, 1, p. 1182-1191

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Formulating Inhalable Dry Powders Using Two-Fluid and Three-Fluid Nozzle Spray Drying

    Leng, D., Thanki, K., Foged, Camilla & Yang, Mingshi, 1 Nov 2018, In: Pharmaceutical Research. 35, 12, 12 p., 247.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Formulation of RNA interference-based drugs for pulmonary delivery: challenges and opportunities

    Thanki, K., Blum, K. G., Thakur, A., Rose, F. & Foged, Camilla, Oct 2018, In: Therapeutic Delivery. 9, 10, p. 731-749 19 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Grand Challenges in Vaccine Delivery: Lessons Learned From the COVID-19 Vaccine Rollout

    Foged, Camilla, 2022, In: Frontiers in Drug Delivery. 2, 4 p., 964298.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Identification of Factors of Importance for Spray Drying of Small Interfering RNA-Loaded Lipidoid-Polymer Hybrid Nanoparticles for Inhalation

    Dormenval, C., Lokras, Abhijeet, Cano-Garcia, G., Wadhwa, A., Thanki, K., Rose, F., Thakur, A., Franzyk, Henrik & Foged, Camilla, 2019, In: Pharmaceutical Research. 36, 10, 142.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Identification of p38α MAP kinase inhibitors by pharmacophore based virtual screening

    Gangwal, R. P., Das, N. R., Thanki, K., Damre, M. V., Dhoke, G. V., Sharma, S. S., Jain, S. & Sangamwar, A. T., Apr 2014, In: Journal of Molecular Graphics and Modelling. 49, p. 18-24 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Immune Reactions in the Delivery of RNA Interference-Based Therapeutics: Mechanisms and Opportunities

    Thanki, K., Falkenberg, E., Gangloff, M. & Foged, Camilla, 31 Aug 2018, Immune Effects of Biopharmaceuticals and Nanomedicine. Bawa, R., Szebeni, J. & Audette, G. (eds.). Pan Stanford, 32 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  44. Published

    Immune responses induced by nano-self-assembled lipid adjuvants based on a monomycoloyl glycerol analogue after vaccination with the Chlamydia trachomatis major outer membrane protein

    Rodrigues, L., Raftopoulos, K. N., Tandrup Schmidt, S., Schneider, F., Dietz, H., Rades, Thomas, Franzyk, Henrik, Pedersen, Anders Elm, Papadakis, C. M., Christensen, D., Winter, G., Foged, Camilla & Hubert, M., 10 Sep 2018, In: Journal of controlled release : official journal of the Controlled Release Society. 285, p. 12-22 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Immunogenicity Testing of Lipidoids In Vitro and In Silico: Modulating Lipidoid-Mediated TLR4 Activation by Nanoparticle Design

    de Groot, A. M., Thanki, K., Gangloff, M., Falkenberg, E., Zeng, X., van Bijnen, D. C. J., van Eden, W., Franzyk, Henrik, Nielsen, Hanne Mørck, Broere, F., Gay, N. J., Foged, Camilla & Sijts, A. J. A. M., 1 Jun 2018, In: Molecular Therapy - Nucleic Acids. 11, p. 159-169 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Immunological and physical evaluation of the multistage tuberculosis subunit vaccine candidate H56/CAF01 formulated as a spray-dried powder

    Thakur, A., Ingvarsson, P. T., Schmidt, S. T., Rose, F., Andersen, P., Christensen, D. & Foged, Camilla, 31 May 2018, In: Vaccine. 36, 23, p. 3331-3339 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Improved insulin loading in poly (lactic-co-glycolic) acid (PLGA) nanoparticles upon self-assembly with lipids

    Garcia Diaz, M., Foged, Camilla & Nielsen, Hanne Mørck, 2015, In: International Journal of Pharmaceutics. 482, p. 84-91 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Improved stability and antidiabetic potential of insulin containing folic acid functionalized polymer stabilized multilayered liposomes following oral administration

    Agrawal, A. K., Harde, H., Thanki, K. & Jain, S., 13 Jan 2014, In: Biomacromolecules. 15, 1, p. 350-60 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Induction of CD8+ T-cell responses against subunit antigens by the novel cationic liposomal CAF09 adjuvant

    Korsholm, K. S., Hansen, J., Karlsen, K., Filskov, J., Mikkelsen, M., Lindenstrøm, T., Schmidt, S. T., Andersen, P. & Christensen, D., 30 Jun 2014, In: Vaccine. 32, 31, p. 3927-35 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Induction of Cytotoxic T-Lymphocyte Responses Upon Subcutaneous Administration of a Subunit Vaccine Adjuvanted With an Emulsion Containing the Toll-Like Receptor 3 Ligand Poly(I:C)

    Schmidt, S. T., Pedersen, G. K., Neustrup, M. A., Korsholm, K. S., Rades, Thomas, Andersen, P., Foged, Camilla & Christensen, D., 30 Apr 2018, In: Frontiers in Immunology. 9, 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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