Vaccine Design and Delivery

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  1. 2007
  2. Published

    Liposomes for phospholipase A2 triggered siRNA release: preparation and in vitro test

    Foged, Camilla, Nielsen, Hanne Mørck & Frøkjær, Sven, 2007, In: Internation Journal of Pharmaceutics. 331, 2, p. 160-166

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. 2010
  4. Published

    CAF01 liposomes as a mucosal vaccine adjuvant: In vitro and in vivo investigations

    Christensen, D., Foged, Camilla, Rosenkrands, I., Lundberg, C. V., Andersen, P., Agger, E. M. & Nielsen, Hanne Mørck, 2010, In: Internation Journal of Pharmaceutics. 390, p. 19-24

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    A study on the prevalence of bovine tuberculosis in farmed dairy cattle in Himachal Pradesh

    Thakur, A., Sharma, M., Katoch, V. C., Dhar, P. & Katoch, R. C., 1 Dec 2010, In: Veterinary World. 3, 9, p. 408-414 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. 2012
  7. Published

    Diffraction studies on natural and model lipid bilayers

    Sebastiani, Federica, Harvey, R., Khanniche, S., Artero, J. B., Haertlein, M. & Fragneto, G., 2012, In: European physical journal-Special topics.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. 2013
  9. Published

    Membrane thickness and the mechanism of action of the short peptaibol trichogin GA IV.

    Bobone, S., Gerelli, Y., De, Z. M., Bocchinfuso, G., Farrotti, A., Orioni, B., Sebastiani, Federica, Latter, E., Penfold, J., Senesi, R., Formaggio, F., Palleschi, A., Toniolo, C., Fragneto, G. & Stella, L., Mar 2013, In: B B A - Biomembranes.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. 2014
  11. Published

    The supramolecular structure is decisive for the immunoactivity of a mycobacterial lipid in vitro.

    Martin-Bertelsen, Birte, Korsholm, K. S., Christensen, D., Franzyk, Henrik, Yaghmur, Anan & Foged, Camilla, 2014. 1 p.

    Research output: Contribution to conference › Poster › Research

  12. Published

    Improved stability and antidiabetic potential of insulin containing folic acid functionalized polymer stabilized multilayered liposomes following oral administration

    Agrawal, A. K., Harde, H., Thanki, K. & Jain, S., 13 Jan 2014, In: Biomacromolecules. 15, 1, p. 350-60 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    One-Step Production of Protein-Loaded PLGA Microparticles via Spray Drying Using 3-Fluid Nozzle

    Wan, F., Maltesen, M. J., Andersen, S. K., Bjerregaard, S., Foged, Camilla, Rantanen, Jukka & Yang, Mingshi, 19 Feb 2014, In: Pharmaceutical Research. 31, 8, p. 1969-1977 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Macromolecular bipill of gemcitabine and methotrexate facilitates tumor-specific dual drug therapy with higher benefit-to-risk ratio

    Das, M., Jain, R., Agrawal, A. K., Thanki, K. & Jain, S., 19 Mar 2014, In: Bioconjugate Chemistry. 25, 3, p. 501-9 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Identification of p38α MAP kinase inhibitors by pharmacophore based virtual screening

    Gangwal, R. P., Das, N. R., Thanki, K., Damre, M. V., Dhoke, G. V., Sharma, S. S., Jain, S. & Sangamwar, A. T., Apr 2014, In: Journal of Molecular Graphics and Modelling. 49, p. 18-24 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Solidified self-nanoemulsifying formulation for oral delivery of combinatorial therapeutic regimen: part II in vivo pharmacokinetics, antitumor efficacy and hepatotoxicity

    Jain, A. K., Thanki, K. & Jain, S., Apr 2014, In: Pharmaceutical Research. 31, 4, p. 946-58 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Solidified self-nanoemulsifying formulation for oral delivery of combinatorial therapeutic regimen: part I. Formulation development, statistical optimization, and in vitro characterization

    Jain, A. K., Thanki, K. & Jain, S., Apr 2014, In: Pharmaceutical Research. 31, 4, p. 923-45 23 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Bicontinuous cubic liquid crystalline nanoparticles for oral delivery of Doxorubicin: implications on bioavailability, therapeutic efficacy, and cardiotoxicity

    Swarnakar, N. K., Thanki, K. & Jain, S., May 2014, In: Pharmaceutical Research. 31, 5, p. 1219-38 20 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Induction of CD8+ T-cell responses against subunit antigens by the novel cationic liposomal CAF09 adjuvant

    Korsholm, K. S., Hansen, J., Karlsen, K., Filskov, J., Mikkelsen, M., Lindenstrøm, T., Schmidt, S. T., Andersen, P. & Christensen, D., 30 Jun 2014, In: Vaccine. 32, 31, p. 3927-35 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Novel self-nanoemulsifying formulation of quercetin: Implications of pro-oxidant activity on the anticancer efficacy

    Jain, A. K., Thanki, K. & Jain, S., Jul 2014, In: Nanomedicine: Nanotechnology, Biology and Medicine. 10, 5, p. 959-69 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Ozonolysis of methyl oleate monolayers at the air-water interface: oxidation kinetics, reaction products and atmospheric implications.

    Pfrang, C., Sebastiani, Federica, Lucas, C., King, M., Hoare, I., Chang, D. & Campbell, R., Jul 2014, In: Phys. Chem. Chem. Phys..

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Enhanced antitumor efficacy and counterfeited cardiotoxicity of combinatorial oral therapy using Doxorubicin- and Coenzyme Q10-liquid crystalline nanoparticles in comparison with intravenous Adriamycin

    Swarnakar, N. K., Thanki, K. & Jain, S., Aug 2014, In: Nanomedicine: Nanotechnology, Biology and Medicine. 10, 6, p. 1231-41 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    The surface charge of liposomal adjuvants is decisive for their interactions with the Calu-3 and A549 airway epithelial cell culture models

    Ingvarsson, P. T., Rasmussen, I. S., Viaene, M., Irlik, P. J., Nielsen, Hanne Mørck & Foged, Camilla, Aug 2014, In: European Journal of Pharmaceutics and Biopharmaceutics. 87, 3, p. 480-8 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    The Effect of Protein PEGylation on Physical Stability in Liquid Formulation

    Holm, L. S., Mcumber, A., Rasmussen, J. E., Obiols-Rabasa, M., Thulstrup, Peter Waaben, Kasimova, M. R., Randolph, T. W. & van de Weert, Marco, 21 Aug 2014, In: Journal of Pharmaceutical Sciences. 103, 10, p. 3043-3054 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Complexity in the therapeutic delivery of RNAi medicines: an analytical challenge

    Colombo, S., Zeng, X., Ragelle, H. & Foged, Camilla, Sep 2014, In: Expert Opinion on Drug Delivery. 11, 9, p. 1481-95 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    A stable nanoparticulate DDA/MMG formulation acts synergistically with CpG ODN 1826 to enhance the CD4(+) T-cell response

    Karlsen, K., Korsholm, K. S., Mortensen, R., Ghiasi, S. M., Andersen, P., Foged, Camilla & Christensen, D., Dec 2014, In: Nanomedicine. 9, 17, p. 2625-38 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. 2015
  28. Published

    Classification of vaccines

    Kallerup, R. S. & Foged, Camilla, 2015, Subunit vaccine delivery. Foged, C., Rades, T., Perrie, Y. & Hooks, S. (eds.). Springer, p. 15-29 15 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  29. Published

    Complementarity of neutron reflectometry and ellipsometry for the study of atmospheric reactions at the air–water interface

    Sebastiani, Federica, Campbell, R. A. & Pfrang, C., 2015, In: RSC Adv..

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Engineering of a novel adjuvant based on lipid-polymer hybrid nanoparticles: A quality-by-design approach

    Rose, F., Wern, J. E., Ingvarsson, P. T., van de Weert, Marco, Andersen, P., Follmann, F. & Foged, Camilla, 2015, In: Journal of controlled release : official journal of the Controlled Release Society. 210, p. 48-57 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Improved insulin loading in poly (lactic-co-glycolic) acid (PLGA) nanoparticles upon self-assembly with lipids

    Garcia Diaz, M., Foged, Camilla & Nielsen, Hanne Mørck, 2015, In: International Journal of Pharmaceutics. 482, p. 84-91 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Influence of trehalose 6,6'-diester (TDX) chain length on the physicochemical and immunopotentiating properties of DDA/TDX liposomes

    Kallerup, R. S., Madsen, C. M., Schiøth, M. L., Franzyk, Henrik, Rose, F., Christensen, D., Korsholm, K. S. & Foged, Camilla, 2015, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 90, p. 80-89 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Spread Films of Human Serum Albumin at the Air–Water Interface: Optimization, Morphology, and Durability

    Campbell, R. A., Ang, J. C., Sebastiani, Federica, Tummino, A. & White, J. W., 2015, In: Langmuir.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Subunit Vaccine Delivery: Advances in Delivery Science and Technology

    Foged, Camilla, Rades, Thomas, Perrie, Y. & Hook, S., 2015, New York.

    Research output: Book/Report › Book › Research › peer-review

  35. Published

    Surface coating of siRNA-peptidomimetic nano-self-assemblies with anionic lipid bilayers: Enhanced gene silencing and reduced adversed effects in vitro

    Zeng, X., de Groot, A. M., Sijts, A., Blenke, E. O., Colombo, S., van Eden, W., Franzyk, Henrik, Nielsen, Hanne Mørck & Foged, Camilla, 2015, In: Nanoscale. 7, 46, p. 19687-19698 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Transcutaneous immunization

    Rattanapak, T., Foged, Camilla & Hook, S., 2015, Subunit vaccine delivery. London: Springer, p. 347-369 23 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  37. Published

    Mechanistic profiling of the siRNA delivery dynamics of lipid-polymer hybrid nanoparticles

    Colombo, S., Cun, D., Remaut, K., Bunker, M., Zhang, J., Martin-Bertelsen, Birte, Yaghmur, Anan, Braeckmans, K., Nielsen, Hanne Mørck & Foged, Camilla, 10 Mar 2015, In: Journal of Controlled Release. 201, p. 22-31 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Intracellular siRNA delivery dynamics of integrin-targeted, PEGylated chitosan-poly(ethylene imine) hybrid nanoparticles: A mechanistic insight

    Ragelle, H., Colombo, S., Pourcelle, V., Vanvarenberg, K., Vandermeulen, G., Bouzin, C., Marchand-Brynaert, J., Feron, O., Foged, Camilla & Préat, V., 10 Aug 2015, In: Journal of Controlled Release. 211, p. 1-9 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. 2016
  40. Published

    Nano-self-assemblies based on synthetic analogues of mycobacterial monomycoloyl glycerol and DDA: Supramolecular structure and adjuvant efficacy

    Martin-Bertelsen, Birte, Korsholm, K. S., Christensen, D., Franzyk, Henrik, Yaghmur, Anan & Foged, Camilla, 2016, In: Molecular Pharmaceutics. 13, 8, p. 2771-2781 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Thermostable Subunit Vaccines for Pulmonary Delivery: How Close Are We?

    Foged, Camilla, 2016, In: Current Pharmaceutical Design. 22, 17, p. 2561-2576 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Liposome-Based Adjuvants for Subunit Vaccines: Formulation Strategies for Subunit Antigens and Immunostimulators

    Schmidt, S. T., Foged, Camilla, Korsholm, K. S., Rades, Thomas & Christensen, D., 10 Mar 2016, In: Pharmaceutics. 8, 1, 22 p., 7.

    Research output: Contribution to journal › Review › Research › peer-review

  43. Published

    Delivery of siRNA Complexed with Palmitoylated α-Peptide/β-Peptoid Cell-Penetrating Peptidomimetics: Membrane Interaction and Structural Characterization of a Lipid-Based Nanocarrier System.

    Jing, X., Foged, Camilla, Martin-Bertelsen, Birte, Yaghmur, Anan, Knapp, K. M., Malmsten, M., Franzyk, Henrik & Nielsen, Hanne Mørck, 6 Jun 2016, In: Molecular Pharmaceutics. 13, 6, p. 1739-1749 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Trehalose diester glycolipids are superior to the monoesters in binding to Mincle, activation of macrophages invitro and adjuvant activity invivo

    Huber, A., Kallerup, R. S., Korsholm, K. S., Franzyk, Henrik, Lepenies, B., Christensen, D., Foged, Camilla & Lang, R., Aug 2016, In: Innate Immunity. 22, 6, p. 405-418 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    The administration route is decisive for the ability of the vaccine adjuvant CAF09 to induce antigen-specific CD8(+) T-cell responses: The immunological consequences of the biodistribution profile

    Schmidt, S. T., Khadke, S., Korsholm, K. S., Perrie, Y., Rades, Thomas, Andersen, P., Foged, Camilla & Christensen, D., 26 Aug 2016, In: Journal of controlled release : official journal of the Controlled Release Society. 239, p. 107-117 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Conserved molecular superlattices in a series of homologous synthetic mycobacterial cell-wall lipids forming interdigitated bilayers

    Martin-Bertelsen, Birte, Yaghmur, Anan, Franzyk, Henrik, Justesen, S., Kirkensgaard, Jacob Judas Kain & Foged, Camilla, 7 Nov 2016, In: Langmuir. 32, 48, p. 12693–12701 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. 2017
  48. Published

    Efficient Pulmonary Delivery of siRNA Using Lipid-polymer Hybrid Nanoparticles (LPNs): A quality-by-design approach for highly systematic optimization of LPNs

    Thanki, K., Zeng, X., Justesen, S., Tejlmann, S., Falkenberg, E., Nielsen, Hanne Mørck, Franzyk, Henrik & Foged, Camilla, 2017.

    Research output: Contribution to conference › Poster › Research

  49. Published

    Quality-by-design in nanomedicine: Highly systematic optimization of lipid-polymer hybrid nanoparticles for efficacious and safe intracellular delivery of cargo siRNA

    Zeng, X., Nielsen, Hanne Mørck, Franzyk, Henrik & Foged, Camilla, 2017.

    Research output: Contribution to conference › Conference abstract for conference › Research

  50. Published

    Simultaneous neutron reflectometry and infrared reflection absorption spectroscopy (IRRAS) study of mixed monolayer reactions at the air-water interface

    Skoda, M. W. A., Thomas, B., Hagreen, M., Sebastiani, Federica & Pfrang, C., 2017, In: RSC Advances.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    Synthesis and Characterisation of an Array of Lipidoid Analogues for RNA Interference Therapy

    Falkenberg, E., de Groot, A. M., Sijts, A. J. A. M., Thanki, K., Zeng, X., Nielsen, Hanne Mørck, Franzyk, Henrik & Foged, Camilla, 2017.

    Research output: Contribution to conference › Poster › Research

  52. Published

    Structural Analysis of Multi-component Amyloid Systems by Chemometric SAXS Data Decomposition

    Trillo, I. F. H., Jensen, M. G., van Maarschalkerweerd, A., Tauler, R., Vestergaard, Bente & Bernadó, P., 3 Jan 2017, In: Structure. 25, 1, p. 5–15 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    Adjuvants based on synthetic mycobacterial cord factor analogues: Biophysical properties of neat glycolipids and nano-self-assemblies with DDA

    Kallerup, R. S., Franzyk, Henrik, Schiøth, M. L., Justesen, S., Martin-Bertelsen, Birte, Rose, F., Madsen, C. M., Christensen, D., Korsholm, K. S., Yaghmur, Anan & Foged, Camilla, 12 May 2017, In: Molecular Pharmaceutics. 14, 7, p. 2294-2306 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. Published

    Inhalable siRNA-loaded nano-embedded microparticles engineered using microfluidics and spray drying

    Agnoletti, M., Bohr, A., Thanki, K., Wan, F., Zeng, X., Bøtker, Johan Peter, Yang, Mingshi & Foged, Camilla, Nov 2017, In: European Journal of Pharmaceutics and Biopharmaceutics. 120, p. 9-21

    Research output: Contribution to journal › Journal article › Research › peer-review

  55. 2018
  56. Submitted

    Anchoring of hydrophilic coating polymers onto charged liposomes via attractive electrostatic interactions using charged tags to control the surface charge drainage properties and cellular targeting

    Andersen, P. L., Christensen, D., Franzyk, Henrik, Foged, Camilla & Schmidt, S. T., 2018, (Submitted)

    Research output: Patent

  57. Published

    Dual-Isotope SPECT/CT Imaging of the Tuberculosis Subunit Vaccine H56/CAF01: Induction of Strong Systemic and Mucosal IgA and T-Cell Responses in Mice Upon Subcutaneous Prime and Intrapulmonary Boost Immunization

    Thakur, A., Rodríguez-Rodríguez, C., Saatchi, K., Rose, F., Esposito, T., Nosrati, Z., Andersen, P., Christensen, D., Häfeli, U. O. & Foged, Camilla, 2018, In: Frontiers in Immunology. 9, 21 p., 2825.

    Research output: Contribution to journal › Journal article › Research › peer-review

  58. Published

    Insight into Nanoscale Network of Spray-dried Polymeric Particles: Role of Polymer Molecular Conformation

    Wan, F., Larsen, F. H., Nunes Bordallo, Heloisa, Foged, Camilla, Rantanen, Jukka & Yang, Mingshi, 2018, In: A C S Applied Materials and Interfaces. 10, 43, p. 36686-36692

    Research output: Contribution to journal › Journal article › Research › peer-review

  59. Published

    Lipid-polymer hybrid nanoparticles (LPNs) for efficient pulmonary delivery of nucleic acids: Lessons learnt from quality-by-design based optimization, immunogenicity studies, in vitro release experiments, in vivo biodistribution and efficacy studies

    Thanki, K., Thakur, A., de Groot, A. M., Geyer, A., Fraire, J., Falkenberg, E., Van Eygen, H., Putteman, E., Van Bijnen, D. C. J., Zeng, X., Sami, H., Gehrig, S., Justesen, S., Franzyk, H., Broere, F., van Eden, W., Sijts, A. J. A. M., Ogris, M., Nielsen, H. M., Braeckmans, K. & 1 others, Foged, Camilla, 2018.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

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