Vaccine Design and Delivery

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  1. Published

    Inhalable siRNA-loaded nano-embedded microparticles engineered using microfluidics and spray drying

    Agnoletti, M., Bohr, A., Thanki, K., Wan, F., Zeng, X., Bøtker, Johan Peter, Yang, Mingshi & Foged, Camilla, Nov 2017, In: European Journal of Pharmaceutics and Biopharmaceutics. 120, p. 9-21

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Improved stability and antidiabetic potential of insulin containing folic acid functionalized polymer stabilized multilayered liposomes following oral administration

    Agrawal, A. K., Harde, H., Thanki, K. & Jain, S., 13 Jan 2014, In: Biomacromolecules. 15, 1, p. 350-60 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Design and evaluation of microemulsion-based efinaconazole formulations for targeted treatment of onychomycosis through transungual route: Ex vivo and nail clipping studies

    Agrawal, V., Patel, R., Patel, M., Thanki, K. & Mishra, S., 2021, In: Colloids and Surfaces B: Biointerfaces. 201, 9 p., 111652.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Elucidating the nanostructure of small interfering RNA-loaded lipidoid-polymer hybrid nanoparticles

    Aljabbari, Anas Samir Mohammad, Lokras, Abhijeet, Kirkensgaard, Jacob Judas Kain, Rades, Thomas, Franzyk, Henrik, Thakur, A., Zhang, Y. & Foged, Camilla, 2023, In: Journal of Colloid and Interface Science. 633, p. 907-922

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Submitted

    Anchoring of hydrophilic coating polymers onto charged liposomes via attractive electrostatic interactions using charged tags to control the surface charge drainage properties and cellular targeting

    Andersen, P. L., Christensen, D., Franzyk, Henrik, Foged, Camilla & Schmidt, S. T., 2018, (Submitted)

    Research output: Patent

  6. Published

    Membrane thickness and the mechanism of action of the short peptaibol trichogin GA IV.

    Bobone, S., Gerelli, Y., De, Z. M., Bocchinfuso, G., Farrotti, A., Orioni, B., Sebastiani, Federica, Latter, E., Penfold, J., Senesi, R., Formaggio, F., Palleschi, A., Toniolo, C., Fragneto, G. & Stella, L., Mar 2013, In: B B A - Biomembranes.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Treatment of acute lung inflammation by pulmonary delivery of anti-TNF-α siRNA with PAMAM dendrimers in a murine model

    Bohr, A., Tsapis, N., Foged, Camilla, Andreana, I., Yang, Mingshi & Fattal, E., 2020, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 156, p. 114-120

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Microfluidics-based self-assembly of peptide-loaded microgels: Effect of three dimensional (3D) printed micromixer design

    Borro, B. C., Bohr, A., Bucciarelli, S., Bøtker, Johan Peter, Foged, Camilla, Rantanen, Jukka & Malmsten, Martin, 7 Mar 2019, In: Journal of Colloid and Interface Science. 538, p. 559-568 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Spread Films of Human Serum Albumin at the Air–Water Interface: Optimization, Morphology, and Durability

    Campbell, R. A., Ang, J. C., Sebastiani, Federica, Tummino, A. & White, J. W., 2015, In: Langmuir.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    CAF01 liposomes as a mucosal vaccine adjuvant: In vitro and in vivo investigations

    Christensen, D., Foged, Camilla, Rosenkrands, I., Lundberg, C. V., Andersen, P., Agger, E. M. & Nielsen, Hanne Mørck, 2010, In: Internation Journal of Pharmaceutics. 390, p. 19-24

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Mechanistic profiling of the siRNA delivery dynamics of lipid-polymer hybrid nanoparticles

    Colombo, S., Cun, D., Remaut, K., Bunker, M., Zhang, J., Martin-Bertelsen, Birte, Yaghmur, Anan, Braeckmans, K., Nielsen, Hanne Mørck & Foged, Camilla, 10 Mar 2015, In: Journal of Controlled Release. 201, p. 22-31 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Complexity in the therapeutic delivery of RNAi medicines: an analytical challenge

    Colombo, S., Zeng, X., Ragelle, H. & Foged, Camilla, Sep 2014, In: Expert Opinion on Drug Delivery. 11, 9, p. 1481-95 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Macromolecular bipill of gemcitabine and methotrexate facilitates tumor-specific dual drug therapy with higher benefit-to-risk ratio

    Das, M., Jain, R., Agrawal, A. K., Thanki, K. & Jain, S., 19 Mar 2014, In: Bioconjugate Chemistry. 25, 3, p. 501-9 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Polysaccharide and monosaccharide guided liver delivery of Sorafenib Tosylate: A nano-strategic approach and comparative assessment of hepatospecificity

    Dhawan, V., Lokras, Abhijeet, Joshi, G., Marwah, M., Venkatraman, M., Mohanty, B., Darshan, K., Chaudhari, P., Warawdekar, U., Saraf, M. & Nagarsenker, M., 2022, In: International Journal of Pharmaceutics. 625, 122039.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Polysaccharide conjugates surpass monosaccharide ligands in hepatospecific targeting – Synthesis and comparative in silico and in vitro assessment

    Dhawan, V., Joshi, G., Sutariya, B., Shah, J., Ashtikar, M., Nagarsekar, K., Steiniger, F., Lokras, Abhijeet, Fahr, A., Krishnapriya, M., Warawdekar, U., Saraf, M. & Nagarsenker, M., 2021, In: Carbohydrate Research. 509, 13 p., 108417.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Identification of Factors of Importance for Spray Drying of Small Interfering RNA-Loaded Lipidoid-Polymer Hybrid Nanoparticles for Inhalation

    Dormenval, C., Lokras, Abhijeet, Cano-Garcia, G., Wadhwa, A., Thanki, K., Rose, F., Thakur, A., Franzyk, Henrik & Foged, Camilla, 2019, In: Pharmaceutical Research. 36, 10, 142.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Engineering aspects of lipid-based delivery systems: In vivo gene delivery, safety criteria, and translation strategies

    Eş, I., Thakur, A., Mousavi Khaneghah, A., Foged, Camilla & de la Torre, L. G., 2024, In: Biotechnology Advances. 72, 45 p., 108342.

    Research output: Contribution to journal › Review › Research › peer-review

  18. Published

    Synthesis and Characterisation of an Array of Lipidoid Analogues for RNA Interference Therapy

    Falkenberg, E., de Groot, A. M., Sijts, A. J. A. M., Thanki, K., Zeng, X., Nielsen, Hanne Mørck, Franzyk, Henrik & Foged, Camilla, 2017.

    Research output: Contribution to conference › Poster › Research

  19. Published

    Liposomes for phospholipase A2 triggered siRNA release: preparation and in vitro test

    Foged, Camilla, Nielsen, Hanne Mørck & Frøkjær, Sven, 2007, In: Internation Journal of Pharmaceutics. 331, 2, p. 160-166

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Grand Challenges in Vaccine Delivery: Lessons Learned From the COVID-19 Vaccine Rollout

    Foged, Camilla, 2022, In: Frontiers in Drug Delivery. 2, 4 p., 964298.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Omikron: Sådan justerer forskerne en mRNA-vaccine

    Foged, Camilla, 3 Dec 2021, In: ForskerZonen. 2021, december

    Research output: Contribution to journal › Journal article › Communication

  22. Published

    Selected contributions from the 10th European Workshop on Particulate Systems, Copenhagen 19th–20th January 2017

    Foged, Camilla, 2018, In: International Journal of Pharmaceutics. 548, 2, p. 729

    Research output: Contribution to journal › Editorial › Research

  23. Published

    COVID-19: Hvem skal nu vaccineres og hvorfor? Professor giver overblikket: Hvor godt virker vaccinerne? Hvem har især gavn af dem? Og hvad ved vi om bivirkningerne? Professor i vaccinedesign guider dig.

    Foged, Camilla, 16 Sep 2022, In: ForskerZonen. 16.09.2022

    Research output: Contribution to journal › Journal article › Research

  24. Published

    COVID-19: Hvordan sikrer vi, at vores vacciner virker mod de nyeste varianter? Når virus muterer, må vi tilpasse vores vacciner. Hvordan sker det i praksis? Og behøver en vaccine overhovedet være tilpasset den seneste variant for at virke?

    Foged, Camilla, 19 Sep 2022, In: ForskerZonen. 19.09.2022

    Research output: Contribution to journal › Journal article › Communication

  25. Published

    Subunit Vaccine Delivery: Advances in Delivery Science and Technology

    Foged, Camilla, Rades, Thomas, Perrie, Y. & Hook, S., 2015, New York.

    Research output: Book/Report › Book › Research › peer-review

  26. Published

    Thermostable Subunit Vaccines for Pulmonary Delivery: How Close Are We?

    Foged, Camilla, 2016, In: Current Pharmaceutical Design. 22, 17, p. 2561-2576 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Vaccination af børn og unge mod COVID-19: Her er, hvad forskningen viser

    Foged, Camilla, 31 Aug 2021, In: ForskerZonen. 2021, August

    Research output: Contribution to journal › Journal article › Communication

  28. Published

    The Long Road Toward COVID-19 Herd Immunity: Vaccine Platform Technologies and Mass Immunization Strategies

    Frederiksen, L. S. F., Zhang, Y., Foged, Camilla & Thakur, A., 2020, In: Frontiers in Immunology. 11, p. 1817

    Research output: Contribution to journal › Review › Research › peer-review

  29. Published

    Identification of p38α MAP kinase inhibitors by pharmacophore based virtual screening

    Gangwal, R. P., Das, N. R., Thanki, K., Damre, M. V., Dhoke, G. V., Sharma, S. S., Jain, S. & Sangamwar, A. T., Apr 2014, In: Journal of Molecular Graphics and Modelling. 49, p. 18-24 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Improved insulin loading in poly (lactic-co-glycolic) acid (PLGA) nanoparticles upon self-assembly with lipids

    Garcia Diaz, M., Foged, Camilla & Nielsen, Hanne Mørck, 2015, In: International Journal of Pharmaceutics. 482, p. 84-91 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Evolution of the structure of lipid nanoparticles for nucleic acid delivery: From in situ studies of formulation to colloidal stability

    Gilbert, J., Sebastiani, Federica, Arteta, M. Y., Terry, A., Fornell, A., Russell, R., Mahmoudi, N. & Nylander, T., 2024, In: Journal of Colloid and Interface Science. 660, p. 66-76

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Delivery of oligonucleotide-based therapeutics: challenges and opportunities

    Hammond, S. M., Aartsma-Rus, A., Alves, S., Borgos, S. E., Buijsen, R. A. M., Collin, R. W. J., Covello, G., Denti, M. A., Desviat, L. R., Echevarría, L., Foged, C., Gaina, G., Garanto, A., Goyenvalle, A. T., Guzowska, M., Holodnuka, I., Jones, D. R., Krause, S., Lehto, T., Montolio, M. & 2 others, Van Roon-Mom, W. & Arechavala-Gomeza, V., 2021, In: EMBO Molecular Medicine. 13, 4, 23 p., e13243.

    Research output: Contribution to journal › Review › Research › peer-review

  33. Published

    Macrophage phosphoproteome analysis reveals MINCLE-dependent and -independent mycobacterial cord factor signaling

    Hansen, M., Peltier, J., Killy, B., Amin, B., Bodendorfer, B., Härtlova, A., Uebel, S., Bosmann, M., Hofmann, J., Büttner, C., Ekici, A. B., Kuttke, M., Franzyk, Henrik, Foged, Camilla, Beer-Hammer, S., Schabbauer, G., Trost, M. & Lang, R., Apr 2019, In: Molecular and Cellular Proteomics. 18, 4, p. 669-685

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Reconstituted Dry Powder Formulations of ZnO-Adjuvanted Ovalbumin Induce Equivalent Serum Antibody Responses to Ovalbumin Adjuvanted with Alhydrogel® or Cationic Adjuvant Formulation 01 (Caf®01)

    Hellfritzsch, M., Christensen, D., Foged, Camilla, Scherließ, R. & Thakur, A., 2023, 41 p. (SSRN Electronic Journal).

    Research output: Working paper › Preprint › Research

  35. Published

    Reconstituted dry powder formulations of ZnO-adjuvanted ovalbumin induce equivalent antigen specific antibodies but lower T cell responses than ovalbumin adjuvanted with Alhydrogel® or cationic adjuvant formulation 01 (CAF®01)

    Hellfritzsch, M., Christensen, D., Foged, Camilla, Scherließ, R. & Thakur, A., 2023, In: International Journal of Pharmaceutics. 648, 15 p., 123581.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Lipid Nanoparticle-Enabled Intracellular Delivery of Prime Editors

    Herrera-Barrera, M., Gautam, M., Lokras, Abhijeet, Vlasova, K., Foged, Camilla & Sahay, G., 2023, In: The AAPS Journal. 25, 4, 10 p., 65.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    The Effect of Protein PEGylation on Physical Stability in Liquid Formulation

    Holm, L. S., Mcumber, A., Rasmussen, J. E., Obiols-Rabasa, M., Thulstrup, Peter Waaben, Kasimova, M. R., Randolph, T. W. & van de Weert, Marco, 21 Aug 2014, In: Journal of Pharmaceutical Sciences. 103, 10, p. 3043-3054 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Trehalose diester glycolipids are superior to the monoesters in binding to Mincle, activation of macrophages invitro and adjuvant activity invivo

    Huber, A., Kallerup, R. S., Korsholm, K. S., Franzyk, Henrik, Lepenies, B., Christensen, D., Foged, Camilla & Lang, R., Aug 2016, In: Innate Immunity. 22, 6, p. 405-418 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    The surface charge of liposomal adjuvants is decisive for their interactions with the Calu-3 and A549 airway epithelial cell culture models

    Ingvarsson, P. T., Rasmussen, I. S., Viaene, M., Irlik, P. J., Nielsen, Hanne Mørck & Foged, Camilla, Aug 2014, In: European Journal of Pharmaceutics and Biopharmaceutics. 87, 3, p. 480-8 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Solidified self-nanoemulsifying formulation for oral delivery of combinatorial therapeutic regimen: part II in vivo pharmacokinetics, antitumor efficacy and hepatotoxicity

    Jain, A. K., Thanki, K. & Jain, S., Apr 2014, In: Pharmaceutical Research. 31, 4, p. 946-58 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Novel self-nanoemulsifying formulation of quercetin: Implications of pro-oxidant activity on the anticancer efficacy

    Jain, A. K., Thanki, K. & Jain, S., Jul 2014, In: Nanomedicine: Nanotechnology, Biology and Medicine. 10, 5, p. 959-69 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Solidified self-nanoemulsifying formulation for oral delivery of combinatorial therapeutic regimen: part I. Formulation development, statistical optimization, and in vitro characterization

    Jain, A. K., Thanki, K. & Jain, S., Apr 2014, In: Pharmaceutical Research. 31, 4, p. 923-45 23 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Lipidoid-Polymer Hybrid Nanoparticles Loaded with TNF siRNA Suppress Inflammation after Intra-articular Administration in a Murine Experimental Arthritis Model

    Jansen, M. A. A., Klausen, L. H., Thanki, K., Lyngsø, J., Skov Pedersen, J., Franzyk, Henrik, Nielsen, Hanne Mørck, van Eden, W., Dong, M., Broere, F., Foged, Camilla & Zeng, X., 2019, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 142, p. 38-48

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    A bifunctional enzyme of Legionella that distinctly regulates phosphoribosyl ubiquitination of the SidE family effectors

    Jiao, J., Ouyang, X., Xu, Y. & Xiong, X., 2022, In: Journal of Translational Internal Medicine. 10, 2, p. 86-88

    Research output: Contribution to journal › Editorial › Research › peer-review

  45. Published

    Delivery of siRNA Complexed with Palmitoylated α-Peptide/β-Peptoid Cell-Penetrating Peptidomimetics: Membrane Interaction and Structural Characterization of a Lipid-Based Nanocarrier System.

    Jing, X., Foged, Camilla, Martin-Bertelsen, Birte, Yaghmur, Anan, Knapp, K. M., Malmsten, M., Franzyk, Henrik & Nielsen, Hanne Mørck, 6 Jun 2016, In: Molecular Pharmaceutics. 13, 6, p. 1739-1749 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Classification of vaccines

    Kallerup, R. S. & Foged, Camilla, 2015, Subunit vaccine delivery. Foged, C., Rades, T., Perrie, Y. & Hooks, S. (eds.). Springer, p. 15-29 15 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  47. Published

    Influence of trehalose 6,6'-diester (TDX) chain length on the physicochemical and immunopotentiating properties of DDA/TDX liposomes

    Kallerup, R. S., Madsen, C. M., Schiøth, M. L., Franzyk, Henrik, Rose, F., Christensen, D., Korsholm, K. S. & Foged, Camilla, 2015, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 90, p. 80-89 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Adjuvants based on synthetic mycobacterial cord factor analogues: Biophysical properties of neat glycolipids and nano-self-assemblies with DDA

    Kallerup, R. S., Franzyk, Henrik, Schiøth, M. L., Justesen, S., Martin-Bertelsen, Birte, Rose, F., Madsen, C. M., Christensen, D., Korsholm, K. S., Yaghmur, Anan & Foged, Camilla, 12 May 2017, In: Molecular Pharmaceutics. 14, 7, p. 2294-2306 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    A stable nanoparticulate DDA/MMG formulation acts synergistically with CpG ODN 1826 to enhance the CD4(+) T-cell response

    Karlsen, K., Korsholm, K. S., Mortensen, R., Ghiasi, S. M., Andersen, P., Foged, Camilla & Christensen, D., Dec 2014, In: Nanomedicine. 9, 17, p. 2625-38 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Potential mucus rheological consequences of off target siRNA loaded nanoparticle deposition in the lungs

    Katuwal, N., Loretz, B., Thanki, K., Hallbrink, M., Lehr, C., Foged, Camilla, Draget, K. & Nordgård, C. T., 2018, ANNUAL TRANSACTIONS OF THE NORDIC RHEOLOGY SOCIETY. Vol. 26.

    Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research

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