- 2024
- Published
Effect of lipid-polymer hybrid nanoparticles on the biophysical function and lateral structure of pulmonary surfactant: Mechanistic in vitro studies
Xu, Y., Cañadas, O., Alonso, A., Franzyk, Henrik, Thakur, A., Pérez-gil, J. & Foged, Camilla, 2024, In: Journal of Colloid and Interface Science. 654, Part B, p. 1111-1123Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Engineering aspects of lipid-based delivery systems: In vivo gene delivery, safety criteria, and translation strategies
Eş, I., Thakur, A., Mousavi Khaneghah, A., Foged, Camilla & de la Torre, L. G., 2024, In: Biotechnology Advances. 72, 45 p., 108342.Research output: Contribution to journal › Review › Research › peer-review
- Published
Evolution of the structure of lipid nanoparticles for nucleic acid delivery: From in situ studies of formulation to colloidal stability
Gilbert, J., Sebastiani, Federica, Arteta, M. Y., Terry, A., Fornell, A., Russell, R., Mahmoudi, N. & Nylander, T., 2024, In: Journal of Colloid and Interface Science. 660, p. 66-76Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lipid nanoparticles for local delivery of mRNA to the respiratory tract: Effect of PEG-lipid content and administration route
Ongun, Melike, Lokras, Abhijeet, Baghel, Saahil Sandeep, Shi, Zhenning, Schmidt, S. T., Franzyk, Henrik, Rades, Thomas, Sebastiani, Federica, Thakur, A. & Foged, Camilla, 2024, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 198, 10 p., 114266.Research output: Contribution to journal › Journal article › Research › peer-review
- 2023
- Published
Comparative study of lipid nanoparticle-based mRNA vaccine bioprocess with machine learning and combinatorial artificial neural network-design of experiment approach
Maharjan, R., Hada, S., Eun Lee, J., Han, H., Hyun Kim, K., Jin Seo, H., Foged, Camilla & Hoon Jeong, S., 2023, In: International Journal of Pharmaceutics. 640, 13 p., 123012.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Elucidating the nanostructure of small interfering RNA-loaded lipidoid-polymer hybrid nanoparticles
Aljabbari, Anas Samir Mohammad, Lokras, Abhijeet, Kirkensgaard, Jacob Judas Kain, Rades, Thomas, Franzyk, Henrik, Thakur, A., Zhang, Y. & Foged, Camilla, 2023, In: Journal of Colloid and Interface Science. 633, p. 907-922Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Insights into the mechanisms of interaction between inhalable lipid-polymer hybrid nanoparticles and pulmonary surfactant
Xu, Y., Parra-Ortiz, E., Wan, F., Cañadas, O., Garcia-Alvarez, B., Thakur, A., Franzyk, Henrik, Pérez-Gil, J., Malmsten, Martin & Foged, Camilla, 2023, In: Journal of Colloid and Interface Science. 633, p. 511-525Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lipid Nanoparticle-Enabled Intracellular Delivery of Prime Editors
Herrera-Barrera, M., Gautam, M., Lokras, Abhijeet, Vlasova, K., Foged, Camilla & Sahay, G., 2023, In: The AAPS Journal. 25, 4, 10 p., 65.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Malaria biomimetic for tumor targeted drug delivery
Pihl, J., Clausen, T. M., Zhou, J., Krishnan, N., Ørum-Madsen, M. S., Gustavsson, Tobias, Dagil, Robert, Daugaard, M., Choudhary, Swati, Foged, Camilla, Esko, J. D., Zhang, L., Fang, R. H. & Salanti, Ali, 2023, In: ACS Nano. 17, 14, p. 13500–13509Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Manipulating cell motility by Legionella: Speeding up or slowing down?
Xu, Y. & Jin, T., 2023, In: Journal of Translational Internal Medicine. 11, 1, p. 24-25Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Method of manufacturing CAF®09 liposomes affects immune responses induced by adjuvanted subunit proteins
Thakur, A., Wadhwa, A., Lokras, Abhijeet, Amanda Oest Müllertz, O., Christensen, D., Franzyk, Henrik & Foged, Camilla, 2023, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 189, p. 84-97Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pulmonary Administration of the Liposome-Based Adjuvant CAF01: Effect of Surface Charge on Mucosal Adjuvant Function
Müllertz, O. A. O., Andersen, P., Christensen, D., Foged, Camilla & Thakur, A., 2023, In: Molecular Pharmaceutics. 20, 2, p. 953–970Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pulmonary delivery of siRNA-loaded lipid-polymer hybrid nanoparticles: Effect of nanoparticle size
Wadhwa, A., Bobak, T. R., Bohrmann, L., Geczy, R., Sekar, S., Sathyanarayanan, G., Kutter, Jörg P., Franzyk, Henrik, Foged, Camilla, Saatchi, K. & Häfeli, U. O., 2023, In: OpenNano. 13, 12 p., 100180.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reconstituted Dry Powder Formulations of ZnO-Adjuvanted Ovalbumin Induce Equivalent Serum Antibody Responses to Ovalbumin Adjuvanted with Alhydrogel® or Cationic Adjuvant Formulation 01 (Caf®01)
Hellfritzsch, M., Christensen, D., Foged, Camilla, Scherließ, R. & Thakur, A., 2023, 41 p. (SSRN Electronic Journal).Research output: Working paper › Preprint › Research
- Published
Reconstituted dry powder formulations of ZnO-adjuvanted ovalbumin induce equivalent antigen specific antibodies but lower T cell responses than ovalbumin adjuvanted with Alhydrogel® or cationic adjuvant formulation 01 (CAF®01)
Hellfritzsch, M., Christensen, D., Foged, Camilla, Scherließ, R. & Thakur, A., 2023, In: International Journal of Pharmaceutics. 648, 15 p., 123581.Research output: Contribution to journal › Journal article › Research › peer-review
- 2022
- Published
COVID-19: Hvordan sikrer vi, at vores vacciner virker mod de nyeste varianter? Når virus muterer, må vi tilpasse vores vacciner. Hvordan sker det i praksis? Og behøver en vaccine overhovedet være tilpasset den seneste variant for at virke?
Foged, Camilla, 19 Sep 2022, In: ForskerZonen. 19.09.2022Research output: Contribution to journal › Journal article › Communication
- Published
COVID-19: Hvem skal nu vaccineres og hvorfor? Professor giver overblikket: Hvor godt virker vaccinerne? Hvem har især gavn af dem? Og hvad ved vi om bivirkningerne? Professor i vaccinedesign guider dig.
Foged, Camilla, 16 Sep 2022, In: ForskerZonen. 16.09.2022Research output: Contribution to journal › Journal article › Research
- Published
A bifunctional enzyme of Legionella that distinctly regulates phosphoribosyl ubiquitination of the SidE family effectors
Jiao, J., Ouyang, X., Xu, Y. & Xiong, X., 2022, In: Journal of Translational Internal Medicine. 10, 2, p. 86-88Research output: Contribution to journal › Editorial › Research › peer-review
- Published
Adjuvants, immunomodulators, and adaptogens
Milicic, A., Reinke, S., Fergusson, J., Lindblad, E. B., Hu, K., Thakur, A., Corby, G., Longet, S., Górska, S., Razim, A., Morein, B., Luchner, M., Christensen, D., Mrenoshki, S., Ceylan, S. E., Gizurarson, S. & Ugwu, M. C., 2022, Vaccinology and Methods in Vaccine Research. Elsevier, p. 223-280Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Grand Challenges in Vaccine Delivery: Lessons Learned From the COVID-19 Vaccine Rollout
Foged, Camilla, 2022, In: Frontiers in Drug Delivery. 2, 4 p., 964298.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhalable Composite Microparticles Containing siRNA-Loaded Lipid-Polymer Hybrid Nanoparticles: Saccharides and Leucine Preserve Aerosol Performance and Long-Term Physical Stability
Xu, You, Turan, E. T., Shi, Z., Franzyk, Henrik, Thakur, A. & Foged, Camilla, 2022, In: Frontiers in Drug Delivery. 2, 15 p., 945459.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Leucine improves the aerosol performance of dry powder inhaler formulations of siRNA-loaded nanoparticles
Xu, Y., Harinck, L., Lokras, Abhijeet, Gerde, P., Selg, E., Sjöberg, C., Franzyk, Henrik, Thakur, A. & Foged, Camilla, 2022, In: International Journal of Pharmaceutics. 621, 14 p., 121758.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lipid Nanoparticle-Mediated Delivery of Therapeutic and Prophylactic mRNA: Immune Activation by Ionizable Cationic Lipids
Ongun, Melike, Lokras, Abhijeet, Foged, Camilla & Thakur, A., 2022, Messenger RNA Therapeutics. Springer, p. 237-255 (RNA Technologies, Vol. 13).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Optimizing the design and dosing of dry powder inhaler formulations of the cationic liposome adjuvant CAF®01 for pulmonary immunization
Thakur, A., Xu, Y., Cano-Garcia, G., Feng, S., Rose, F., Gerde, P., Andersen, Peter, Christensen, D. & Foged, Camilla, 2022, In: Frontiers in Drug Delivery. 2, 973599.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Polysaccharide and monosaccharide guided liver delivery of Sorafenib Tosylate: A nano-strategic approach and comparative assessment of hepatospecificity
Dhawan, V., Lokras, Abhijeet, Joshi, G., Marwah, M., Venkatraman, M., Mohanty, B., Darshan, K., Chaudhari, P., Warawdekar, U., Saraf, M. & Nagarsenker, M., 2022, In: International Journal of Pharmaceutics. 625, 122039.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Simultaneous quantification of multiple RNA cargoes co-loaded into nanoparticle-based delivery systems
Lokras, Abhijeet, Chakravarty, A., Rades, Thomas, Christensen, D., Franzyk, Henrik, Thakur, A. & Foged, Camilla, 2022, In: International Journal of Pharmaceutics. 626, 13 p., 122171.Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
Omikron: Sådan justerer forskerne en mRNA-vaccine
Foged, Camilla, 3 Dec 2021, In: ForskerZonen. 2021, decemberResearch output: Contribution to journal › Journal article › Communication
- Published
Vaccination af børn og unge mod COVID-19: Her er, hvad forskningen viser
Foged, Camilla, 31 Aug 2021, In: ForskerZonen. 2021, AugustResearch output: Contribution to journal › Journal article › Communication
- Published
Adsorption of protein antigen to the cationic liposome adjuvant CAF®01 is required for induction of Th1 and Th17 responses but not for antibody induction
Wørzner, K., Hvannastein, J., Tandrup Schmidt, S., Foged, Camilla, Rosenkrands, I., Kristian Pedersen, G. & Christensen, D., 2021, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 165, p. 293-305Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Delivery of oligonucleotide-based therapeutics: challenges and opportunities
Hammond, S. M., Aartsma-Rus, A., Alves, S., Borgos, S. E., Buijsen, R. A. M., Collin, R. W. J., Covello, G., Denti, M. A., Desviat, L. R., Echevarría, L., Foged, C., Gaina, G., Garanto, A., Goyenvalle, A. T., Guzowska, M., Holodnuka, I., Jones, D. R., Krause, S., Lehto, T., Montolio, M. & 2 others, , 2021, In: EMBO Molecular Medicine. 13, 4, 23 p., e13243.Research output: Contribution to journal › Review › Research › peer-review
- Published
Design and evaluation of microemulsion-based efinaconazole formulations for targeted treatment of onychomycosis through transungual route: Ex vivo and nail clipping studies
Agrawal, V., Patel, R., Patel, M., Thanki, K. & Mishra, S., 2021, In: Colloids and Surfaces B: Biointerfaces. 201, 9 p., 111652.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Engineering of Solid Dosage Forms of siRNA-Loaded Lipidoid-Polymer Hybrid Nanoparticles Using a Quality-by-Design Approach
Lokras, Abhijeet, Foged, Camilla & Thakur, A., 2021, Design and Delivery of SiRNA Therapeutics. Ditzel, H. J., Tuttolomondo, M. & Kauppinen, S. (eds.). Humana Press, p. 137-157 (Methods in Molecular Biology, Vol. 2282).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Inhaled RNA Therapeutics for Obstructive Airway Diseases: Recent Advances and Future Prospects
Xu, You, Thakur, A., Zhang, Y. & Foged, Camilla, 2021, In: Pharmaceutics. 13, 2, 35 p., 77.Research output: Contribution to journal › Review › Research › peer-review
- Published
Polysaccharide conjugates surpass monosaccharide ligands in hepatospecific targeting – Synthesis and comparative in silico and in vitro assessment
Dhawan, V., Joshi, G., Sutariya, B., Shah, J., Ashtikar, M., Nagarsekar, K., Steiniger, F., Lokras, Abhijeet, Fahr, A., Krishnapriya, M., Warawdekar, U., Saraf, M. & Nagarsenker, M., 2021, In: Carbohydrate Research. 509, 13 p., 108417.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rational Vaccine Design in Times of Emerging Diseases: The Critical Choices of Immunological Correlates of Protection, Vaccine Antigen and Immunomodulation
Schijns, V., Majhen, D., Van Der Ley, P., Thakur, A., Summerfield, A., Berisio, R., Nativi, C., Fernández-tejada, A., Álverez-dominguez, C., Gizurarson, S., Zamyatina, A., Molinaro, A., Rosano, C., Jakopin, Ž., Gursel, I. & Mcclean, S., 2021, In: Pharmaceutics. 13, 4, 29 p., 501.Research output: Contribution to journal › Journal article › Research › peer-review
- 2020
- Published
Opportunities and Challenges in the Delivery of mRNA-based Vaccines
Wadhwa, A., Aljabbari, A., Lokras, Abhijeet, Foged, Camilla & Thakur, A., 28 Jan 2020, In: Pharmaceutics. 12, 2, 27 p., 102.Research output: Contribution to journal › Review › Research › peer-review
- Published
Epidemiological and clinical characteristics of 2019 novel coronavirus disease (COVID-19) in Jilin, China A descriptive study
Liu, H., Gao, J., Wang, Y., Jie, J., Luo, J., Xu, Y., Sun, H., Song, L., Li, D., Peng, L. & Hua, S., 2020, In: Medicine. 99, 47, 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inflammasome-Mediated Immunogenicity of Clinical and Experimental Vaccine Adjuvants
Reinke, S., Thakur, A., Gartlan, C., Bezbradica, J. S. & Milicic, A., 2020, In: Vaccines. 8, 3, p. 1-25Research output: Contribution to journal › Review › Research › peer-review
- Published
Intrapulmonary (i.pulmon.) Pull Immunization With the Tuberculosis Subunit Vaccine Candidate H56/CAF01 After Intramuscular (i.m.) Priming Elicits a Distinct Innate Myeloid Response and Activation of Antigen-Presenting Cells Than i.m. or i.pulmon. Prime Immunization Alone
Thakur, A., Pinto, F. E., Hansen, Harald S., Andersen, Peter, Christensen, D., Janfelt, Christian & Foged, Camilla, 2020, In: Frontiers in Immunology. 11, p. 803Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Modulation of immune responses using adjuvants to facilitate therapeutic vaccination
Schijns, V., Fernández‐tejada, A., Barjaktarović, Ž., Bouzalas, I., Brimnes, J., Chernysh, S., Gizurarson, S., Gursel, I., Jakopin, Ž., Lawrenz, M., Nativi, C., Paul, S., Pedersen, G. K., Rosano, C., Ruiz‐de‐angulo, A., Slütter, B., Thakur, A., Christensen, D. & Lavelle, E. C., 2020, In: Immunological Reviews. 296, 1, p. 169-190Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nanoparticles for mucosal vaccine delivery
Thakur, A. & Foged, Camilla, 2020, Nanoengineered Biomaterials for Advanced Drug Delivery. Woodhead Publishing, p. 603-646 44 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Nanoparticles for mucosal vaccine delivery
Thakur, A. & Foged, Camilla, 2020, Nanoengineered Biomaterials for Advanced Drug Delivery. Mozafari, M. (ed.). 1 ed. ElsevierResearch output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Novel drug delivery systems targeting oxidative stress in chronic obstructive pulmonary disease: a review
Xu, Y., Liu, H. & Song, L., 2020, In: Journal of Nanobiotechnology. 18, 1, 25 p., 145.Research output: Contribution to journal › Review › Research › peer-review
- Published
Optimizing the Intracellular Delivery of Therapeutic Anti-inflammatory TNF-α siRNA to Activated Macrophages Using Lipidoid-Polymer Hybrid Nanoparticles
Lokras, Abhijeet, Thakur, A., Wadhwa, A., Thanki, K., Franzyk, Henrik & Foged, Camilla, 2020, In: Frontiers in Bioengineering and Biotechnology. 8, 14 p., 601155.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
RP-HPLC method for quantitative estimation of Efinaconazole in topical microemulsion and microemulsion-based-gel formulations and in presence of its degradation products
Vikas, A., Rashmin, P., Mrunali, P., Sandip, M. & Kaushik, T., 2020, In: Microchemical Journal. 155, 7 p., 104753.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Technological Approaches for Improving Vaccination Compliance and Coverage
Lemoine, C., Thakur, A., Krajišnik, D., Guyon, R., Longet, S., Razim, A., Górska, S., Pantelić, I., Ilić, T., Nikolić, I., Lavelle, E. C., Gamian, A., Savić, S. & Milicic, A., 2020, In: Vaccines. 8, 2, 28 p., 304.Research output: Contribution to journal › Review › Research › peer-review
- Published
The Long Road Toward COVID-19 Herd Immunity: Vaccine Platform Technologies and Mass Immunization Strategies
Frederiksen, L. S. F., Zhang, Y., Foged, Camilla & Thakur, A., 2020, In: Frontiers in Immunology. 11, p. 1817Research output: Contribution to journal › Review › Research › peer-review
- Published
Treatment of acute lung inflammation by pulmonary delivery of anti-TNF-α siRNA with PAMAM dendrimers in a murine model
Bohr, A., Tsapis, N., Foged, Camilla, Andreana, I., Yang, Mingshi & Fattal, E., 2020, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 156, p. 114-120Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
One-pot synthesis and characterization of ovalbumin-conjugated gold nanoparticles: A comparative study of adjuvanticity against the physical mixture of ovalbumin and gold nanoparticles
Yang, Y., Zhang, Y., Thakur, A., Li, R., Xu, H., Wang, Z., Ghavami, M., Tu, Z. & Liu, H., 25 Nov 2019, In: International Journal of Pharmaceutics. 571, 10 p., 118704.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Macrophage phosphoproteome analysis reveals MINCLE-dependent and -independent mycobacterial cord factor signaling
Hansen, M., Peltier, J., Killy, B., Amin, B., Bodendorfer, B., Härtlova, A., Uebel, S., Bosmann, M., Hofmann, J., Büttner, C., Ekici, A. B., Kuttke, M., Franzyk, Henrik, Foged, Camilla, Beer-Hammer, S., Schabbauer, G., Trost, M. & Lang, R., Apr 2019, In: Molecular and Cellular Proteomics. 18, 4, p. 669-685Research output: Contribution to journal › Journal article › Research › peer-review
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Opportunities and Challenges in the Delivery of mRNA-based Vaccines
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221
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Immunogenicity Testing of Lipidoids In Vitro and In Silico: Modulating Lipidoid-Mediated TLR4 Activation by Nanoparticle Design
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Induction of Cytotoxic T-Lymphocyte Responses Upon Subcutaneous Administration of a Subunit Vaccine Adjuvanted With an Emulsion Containing the Toll-Like Receptor 3 Ligand Poly(I:C)
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Latest publications
Evolution of the structure of lipid nanoparticles for nucleic acid delivery: From in situ studies of formulation to colloidal stability
Research output: Contribution to journal › Journal article › Research › peer-review
Effect of lipid-polymer hybrid nanoparticles on the biophysical function and lateral structure of pulmonary surfactant: Mechanistic in vitro studies
Research output: Contribution to journal › Journal article › Research › peer-review
Engineering aspects of lipid-based delivery systems: In vivo gene delivery, safety criteria, and translation strategies
Research output: Contribution to journal › Review › Research › peer-review