- 2019
- Published
Nebulised lipid-polymer hybrid nanoparticles for the delivery of a therapeutic anti-inflammatory microRNA to bronchial epithelial cells
Vencken, S., Foged, Camilla, Ramsey, J. M., Sweeney, L., Cryan, S., MacLoughlin, R. J. & Greene, C. M., Apr 2019, In: ERJ Open Research. 5, 2, 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Design of Inhalable Solid Dosage Forms of Budesonide and Theophylline for Pulmonary Combination Therapy
Leng, D., Kissi, E. O., Löbmann, Korbinian, Thanki, K., Fattal, E., Rades, Thomas, Foged, Camilla & Yang, Mingshi, 7 Mar 2019, In: AAPS PharmSciTech. 20, 3, 137.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Microfluidics-based self-assembly of peptide-loaded microgels: Effect of three dimensional (3D) printed micromixer design
Borro, B. C., Bohr, A., Bucciarelli, S., Bøtker, Johan Peter, Foged, Camilla, Rantanen, Jukka & Malmsten, Martin, 7 Mar 2019, In: Journal of Colloid and Interface Science. 538, p. 559-568 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Qualitative and quantitative analysis of the biophysical interaction of inhaled nanoparticles with pulmonary surfactant by using quartz crystal microbalance with dissipation monitoring
Wan, F., Nylander, T., Foged, Camilla, Yang, Mingshi, Baldursdottir, S. G. & Nielsen, Hanne Mørck, 1 Mar 2019, In: Journal of Colloid and Interface Science. 545, p. 162-171 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Application of a Quality-By-Design Approach to Optimise Lipid-Polymer Hybrid Nanoparticles Loaded with a Splice-Correction Antisense Oligonucleotide: Maximising Loading and Intracellular Delivery
Thanki, K., Papai, S., Lokras, Abhijeet, Rose, F., Falkenberg, E., Franzyk, Henrik & Foged, Camilla, 2019, In: Pharmaceutical Research. 36, 3, 37.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Design of gadoteridol-loaded cationic liposomal adjuvant CAF01 for MRI of lung deposition of intrapulmonary administered particles
Thakur, A., Rose, F., Ansari, S. R., Koch, P., Martini, V., Ovesen, S. L., Quistorff, B., Maritim, S., Hyder, F., Andersen, Peter, Christensen, D., Mori, Yuki & Foged, Camilla, 2019, In: Molecular Pharmaceutics. 16, 11, p. 4725-4737 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of Factors of Importance for Spray Drying of Small Interfering RNA-Loaded Lipidoid-Polymer Hybrid Nanoparticles for Inhalation
Dormenval, C., Lokras, Abhijeet, Cano-Garcia, G., Wadhwa, A., Thanki, K., Rose, F., Thakur, A., Franzyk, Henrik & Foged, Camilla, 2019, In: Pharmaceutical Research. 36, 10, 142.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Intracellular Pathogens: Host Immunity and Microbial Persistence Strategies
Thakur, A., Mikkelsen, H. & Jungersen, G., 2019, In: Journal of Immunology Research. 2019, 24 p., 1356540.Research output: Contribution to journal › Review › Research › peer-review
- Published
Lipidoid-Polymer Hybrid Nanoparticles Loaded with TNF siRNA Suppress Inflammation after Intra-articular Administration in a Murine Experimental Arthritis Model
Jansen, M. A. A., Klausen, L. H., Thanki, K., Lyngsø, J., Skov Pedersen, J., Franzyk, Henrik, Nielsen, Hanne Mørck, van Eden, W., Dong, M., Broere, F., Foged, Camilla & Zeng, X., 2019, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 142, p. 38-48Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mechanistic profiling of the release kinetics of siRNA from lipidoid-polymer hybrid nanoparticles in vitro and in vivo after pulmonary administration
Thanki, K., van Eetvelde, D., Geyer, A., Fraire, J., Hendrix, R., Van Eygen, H., Putteman, E., Sami, H., de Souza Carvalho-Wodarz, C., Franzyk, Henrik, Nielsen, Hanne Mørck, Braeckmans, K., Lehr, C., Ogris, M. & Foged, Camilla, 2019, In: Journal of controlled release : official journal of the Controlled Release Society. 310, p. 82-93Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Preparation, Characterization, and In Vitro Evaluation of Lipidoid-Polymer Hybrid Nanoparticles for siRNA Delivery to the Cytosol
Thanki, K., Zeng, X. & Foged, Camilla, 2019, In: Methods in molecular biology (Clifton, N.J.). 1943, p. 141-152 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2018
- Published
Formulating Inhalable Dry Powders Using Two-Fluid and Three-Fluid Nozzle Spray Drying
Leng, D., Thanki, K., Foged, Camilla & Yang, Mingshi, 1 Nov 2018, In: Pharmaceutical Research. 35, 12, 12 p., 247.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mixed micellar system stabilized with saponins for oral delivery of vitamin K
Sun, F., Ye, C., Thanki, K., Leng, D., van Hasselt, P. M., Hennink, W. E. & van Nostrum, C. F., 1 Oct 2018, In: Colloids and Surfaces B: Biointerfaces. 170, p. 521-528 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Formulation of RNA interference-based drugs for pulmonary delivery: challenges and opportunities
Thanki, K., Blum, K. G., Thakur, A., Rose, F. & Foged, Camilla, Oct 2018, In: Therapeutic Delivery. 9, 10, p. 731-749 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Engineering of budesonide-loaded lipid-polymer hybrid nanoparticles using a quality-by-design approach
Leng, D., Thanki, K., Fattal, E., Foged, Camilla & Yang, Mingshi, 15 Sep 2018, In: International Journal of Pharmaceutics. 548, 2, p. 740-746Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Immune responses induced by nano-self-assembled lipid adjuvants based on a monomycoloyl glycerol analogue after vaccination with the Chlamydia trachomatis major outer membrane protein
Rodrigues, L., Raftopoulos, K. N., Tandrup Schmidt, S., Schneider, F., Dietz, H., Rades, Thomas, Franzyk, Henrik, Pedersen, Anders Elm, Papadakis, C. M., Christensen, D., Winter, G., Foged, Camilla & Hubert, M., 10 Sep 2018, In: Journal of controlled release : official journal of the Controlled Release Society. 285, p. 12-22 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Immune Reactions in the Delivery of RNA Interference-Based Therapeutics: Mechanisms and Opportunities
Thanki, K., Falkenberg, E., Gangloff, M. & Foged, Camilla, 31 Aug 2018, Immune Effects of Biopharmaceuticals and Nanomedicine. Bawa, R., Szebeni, J. & Audette, G. (eds.). Pan Stanford, 32 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Poly(ethylene carbonate)-containing polylactic acid microparticles with rifampicin improve drug delivery to macrophages
Priemel, P. A., Wang, Y., Bohr, A., Water, J. J., Yang, Mingshi & Nielsen, Hanne Mørck, Aug 2018, In: Journal of Pharmacy and Pharmacology. 70, 8, p. 1009-1021Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Immunogenicity Testing of Lipidoids In Vitro and In Silico: Modulating Lipidoid-Mediated TLR4 Activation by Nanoparticle Design
de Groot, A. M., Thanki, K., Gangloff, M., Falkenberg, E., Zeng, X., van Bijnen, D. C. J., van Eden, W., Franzyk, Henrik, Nielsen, Hanne Mørck, Broere, F., Gay, N. J., Foged, Camilla & Sijts, A. J. A. M., 1 Jun 2018, In: Molecular Therapy - Nucleic Acids. 11, p. 159-169 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Unusual Self-Assembly of the Recombinant Chlamydia trachomatis Major Outer Membrane Protein-Based Fusion Antigen CTH522 Into Protein Nanoparticles
Rose, F., Karlsen, K., Jensen, P. R., Jakobsen, R. U., Wood, G. K., Rand, Kasper Dyrberg, Godiksen, H., Andersen, P., Follmann, F. & Foged, Camilla, Jun 2018, In: Journal of Pharmaceutical Sciences. 107, 6, p. 1690-1700 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Immunological and physical evaluation of the multistage tuberculosis subunit vaccine candidate H56/CAF01 formulated as a spray-dried powder
Thakur, A., Ingvarsson, P. T., Schmidt, S. T., Rose, F., Andersen, P., Christensen, D. & Foged, Camilla, 31 May 2018, In: Vaccine. 36, 23, p. 3331-3339 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Folate receptor-targeted mixed polysialic acid micelles for combating rheumatoid arthritis: in vitro and in vivo evaluation
Zhang, N., Xu, C., Li, N., Zhang, S., Fu, L., Chu, X., Hua, H., Zeng, X. & Zhao, Y., 23 May 2018, In: Drug Delivery. 25, 1, p. 1182-1191Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Induction of Cytotoxic T-Lymphocyte Responses Upon Subcutaneous Administration of a Subunit Vaccine Adjuvanted With an Emulsion Containing the Toll-Like Receptor 3 Ligand Poly(I:C)
Schmidt, S. T., Pedersen, G. K., Neustrup, M. A., Korsholm, K. S., Rades, Thomas, Andersen, P., Foged, Camilla & Christensen, D., 30 Apr 2018, In: Frontiers in Immunology. 9, 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nighttime oxidation of surfactants at the air–water interface: effects of chain length, head group and saturation
Sebastiani, Federica, Campbell, R. A., Rastogi, K. & Pfrang, C., 7 Mar 2018, In: Atmospheric Chemistry and Physics.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lipid shell-enveloped polymeric nanoparticles with high integrity of lipid shells improve mucus penetration and interaction with cystic fibrosis-related bacterial biofilms
Wan, F., Nylander, T., Klodzinska, S. N., Foged, Camilla, Yang, Mingshi, Baldursdottir, S. G. & Nielsen, Hanne Mørck, 23 Feb 2018, In: A C S Applied Materials and Interfaces. 10, 13, p. 10678–10687Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of Aggregate Charge and Subphase Ionic Strength on the Properties of Spread Polyelectrolyte/Surfactant Films at the Air/Water Interface under Static and Dynamic Conditions
Tummino, A., Toscano, J., Sebastiani, Federica, Noskov, B. A., Varga, I. & Campbell, R. A., 13 Feb 2018, In: Langmuir. 34, 6, p. 2312-2323 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A strong adjuvant based on glycol-chitosan-coated lipid-polymer hybrid nanoparticles potentiates mucosal immune responses against the recombinant Chlamydia trachomatis fusion antigen CTH522
Rose, F., Erbo Wern, J., Gavins, F., Andersen, P., Follmann, F. & Foged, Camilla, Feb 2018, In: Journal of Controlled Release. 271, p. 88-97 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Submitted
Anchoring of hydrophilic coating polymers onto charged liposomes via attractive electrostatic interactions using charged tags to control the surface charge drainage properties and cellular targeting
Andersen, P. L., Christensen, D., Franzyk, Henrik, Foged, Camilla & Schmidt, S. T., 2018, (Submitted)Research output: Patent
- Published
Dual-Isotope SPECT/CT Imaging of the Tuberculosis Subunit Vaccine H56/CAF01: Induction of Strong Systemic and Mucosal IgA and T-Cell Responses in Mice Upon Subcutaneous Prime and Intrapulmonary Boost Immunization
Thakur, A., Rodríguez-Rodríguez, C., Saatchi, K., Rose, F., Esposito, T., Nosrati, Z., Andersen, P., Christensen, D., Häfeli, U. O. & Foged, Camilla, 2018, In: Frontiers in Immunology. 9, 21 p., 2825.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Insight into Nanoscale Network of Spray-dried Polymeric Particles: Role of Polymer Molecular Conformation
Wan, F., Larsen, F. H., Nunes Bordallo, Heloisa, Foged, Camilla, Rantanen, Jukka & Yang, Mingshi, 2018, In: A C S Applied Materials and Interfaces. 10, 43, p. 36686-36692Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lipid-polymer hybrid nanoparticles (LPNs) for efficient pulmonary delivery of nucleic acids: Lessons learnt from quality-by-design based optimization, immunogenicity studies, in vitro release experiments, in vivo biodistribution and efficacy studies
Thanki, K., Thakur, A., de Groot, A. M., Geyer, A., Fraire, J., Falkenberg, E., Van Eygen, H., Putteman, E., Van Bijnen, D. C. J., Zeng, X., Sami, H., Gehrig, S., Justesen, S., Franzyk, H., Broere, F., van Eden, W., Sijts, A. J. A. M., Ogris, M., Nielsen, H. M., Braeckmans, K. & 1 others, , 2018.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
- Published
Mechanisms of deformable nanovesicles based on insulin-phospholipid complex for enhancing buccal delivery of insulin
Xu, You, Zhang, X., Zhang, Y., Ye, J., Wang, H., Xia, X. & Liu, Y., 2018, In: International Journal of Nanomedicine. 13, p. 7319-7331 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Potential mucus rheological consequences of off target siRNA loaded nanoparticle deposition in the lungs
Katuwal, N., Loretz, B., Thanki, K., Hallbrink, M., Lehr, C., Foged, Camilla, Draget, K. & Nordgård, C. T., 2018, ANNUAL TRANSACTIONS OF THE NORDIC RHEOLOGY SOCIETY. Vol. 26.Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research
- Published
Selected contributions from the 10th European Workshop on Particulate Systems, Copenhagen 19th–20th January 2017
Foged, Camilla, 2018, In: International Journal of Pharmaceutics. 548, 2, p. 729Research output: Contribution to journal › Editorial › Research
- Published
Temperature-Induced Self-Assembly of the Group B Streptococcus (GBS) Fusion Antigen GBS-NN
Rose, F., Roovers, S., Fano, M., Rønholt, Stine, Kirkensgaard, Jacob Judas Kain, Hejnaes, K., Fischer, P. & Foged, Camilla, 2018, In: Molecular Pharmaceutics. 15, p. 2584-2593 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
Inhalable siRNA-loaded nano-embedded microparticles engineered using microfluidics and spray drying
Agnoletti, M., Bohr, A., Thanki, K., Wan, F., Zeng, X., Bøtker, Johan Peter, Yang, Mingshi & Foged, Camilla, Nov 2017, In: European Journal of Pharmaceutics and Biopharmaceutics. 120, p. 9-21Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Adjuvants based on synthetic mycobacterial cord factor analogues: Biophysical properties of neat glycolipids and nano-self-assemblies with DDA
Kallerup, R. S., Franzyk, Henrik, Schiøth, M. L., Justesen, S., Martin-Bertelsen, Birte, Rose, F., Madsen, C. M., Christensen, D., Korsholm, K. S., Yaghmur, Anan & Foged, Camilla, 12 May 2017, In: Molecular Pharmaceutics. 14, 7, p. 2294-2306 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structural Analysis of Multi-component Amyloid Systems by Chemometric SAXS Data Decomposition
Trillo, I. F. H., Jensen, M. G., van Maarschalkerweerd, A., Tauler, R., Vestergaard, Bente & Bernadó, P., 3 Jan 2017, In: Structure. 25, 1, p. 5–15 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Efficient Pulmonary Delivery of siRNA Using Lipid-polymer Hybrid Nanoparticles (LPNs): A quality-by-design approach for highly systematic optimization of LPNs
Thanki, K., Zeng, X., Justesen, S., Tejlmann, S., Falkenberg, E., Nielsen, Hanne Mørck, Franzyk, Henrik & Foged, Camilla, 2017.Research output: Contribution to conference › Poster › Research
- Published
Quality-by-design in nanomedicine: Highly systematic optimization of lipid-polymer hybrid nanoparticles for efficacious and safe intracellular delivery of cargo siRNA
Zeng, X., Nielsen, Hanne Mørck, Franzyk, Henrik & Foged, Camilla, 2017.Research output: Contribution to conference › Conference abstract for conference › Research
- Published
Simultaneous neutron reflectometry and infrared reflection absorption spectroscopy (IRRAS) study of mixed monolayer reactions at the air-water interface
Skoda, M. W. A., Thomas, B., Hagreen, M., Sebastiani, Federica & Pfrang, C., 2017, In: RSC Advances.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Synthesis and Characterisation of an Array of Lipidoid Analogues for RNA Interference Therapy
Falkenberg, E., de Groot, A. M., Sijts, A. J. A. M., Thanki, K., Zeng, X., Nielsen, Hanne Mørck, Franzyk, Henrik & Foged, Camilla, 2017.Research output: Contribution to conference › Poster › Research
- 2016
- Published
Conserved molecular superlattices in a series of homologous synthetic mycobacterial cell-wall lipids forming interdigitated bilayers
Martin-Bertelsen, Birte, Yaghmur, Anan, Franzyk, Henrik, Justesen, S., Kirkensgaard, Jacob Judas Kain & Foged, Camilla, 7 Nov 2016, In: Langmuir. 32, 48, p. 12693–12701 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The administration route is decisive for the ability of the vaccine adjuvant CAF09 to induce antigen-specific CD8(+) T-cell responses: The immunological consequences of the biodistribution profile
Schmidt, S. T., Khadke, S., Korsholm, K. S., Perrie, Y., Rades, Thomas, Andersen, P., Foged, Camilla & Christensen, D., 26 Aug 2016, In: Journal of controlled release : official journal of the Controlled Release Society. 239, p. 107-117 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Trehalose diester glycolipids are superior to the monoesters in binding to Mincle, activation of macrophages invitro and adjuvant activity invivo
Huber, A., Kallerup, R. S., Korsholm, K. S., Franzyk, Henrik, Lepenies, B., Christensen, D., Foged, Camilla & Lang, R., Aug 2016, In: Innate Immunity. 22, 6, p. 405-418 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Delivery of siRNA Complexed with Palmitoylated α-Peptide/β-Peptoid Cell-Penetrating Peptidomimetics: Membrane Interaction and Structural Characterization of a Lipid-Based Nanocarrier System.
Jing, X., Foged, Camilla, Martin-Bertelsen, Birte, Yaghmur, Anan, Knapp, K. M., Malmsten, M., Franzyk, Henrik & Nielsen, Hanne Mørck, 6 Jun 2016, In: Molecular Pharmaceutics. 13, 6, p. 1739-1749 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Liposome-Based Adjuvants for Subunit Vaccines: Formulation Strategies for Subunit Antigens and Immunostimulators
Schmidt, S. T., Foged, Camilla, Korsholm, K. S., Rades, Thomas & Christensen, D., 10 Mar 2016, In: Pharmaceutics. 8, 1, 22 p., 7.Research output: Contribution to journal › Review › Research › peer-review
- Published
Nano-self-assemblies based on synthetic analogues of mycobacterial monomycoloyl glycerol and DDA: Supramolecular structure and adjuvant efficacy
Martin-Bertelsen, Birte, Korsholm, K. S., Christensen, D., Franzyk, Henrik, Yaghmur, Anan & Foged, Camilla, 2016, In: Molecular Pharmaceutics. 13, 8, p. 2771-2781 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Thermostable Subunit Vaccines for Pulmonary Delivery: How Close Are We?
Foged, Camilla, 2016, In: Current Pharmaceutical Design. 22, 17, p. 2561-2576 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
- Published
Intracellular siRNA delivery dynamics of integrin-targeted, PEGylated chitosan-poly(ethylene imine) hybrid nanoparticles: A mechanistic insight
Ragelle, H., Colombo, S., Pourcelle, V., Vanvarenberg, K., Vandermeulen, G., Bouzin, C., Marchand-Brynaert, J., Feron, O., Foged, Camilla & Préat, V., 10 Aug 2015, In: Journal of Controlled Release. 211, p. 1-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Most downloads
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258
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Opportunities and Challenges in the Delivery of mRNA-based Vaccines
Research output: Contribution to journal › Review › Research › peer-review
Published -
222
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Immunogenicity Testing of Lipidoids In Vitro and In Silico: Modulating Lipidoid-Mediated TLR4 Activation by Nanoparticle Design
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
185
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Induction of Cytotoxic T-Lymphocyte Responses Upon Subcutaneous Administration of a Subunit Vaccine Adjuvanted With an Emulsion Containing the Toll-Like Receptor 3 Ligand Poly(I:C)
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Latest publications
Evolution of the structure of lipid nanoparticles for nucleic acid delivery: From in situ studies of formulation to colloidal stability
Research output: Contribution to journal › Journal article › Research › peer-review
Effect of lipid-polymer hybrid nanoparticles on the biophysical function and lateral structure of pulmonary surfactant: Mechanistic in vitro studies
Research output: Contribution to journal › Journal article › Research › peer-review
Engineering aspects of lipid-based delivery systems: In vivo gene delivery, safety criteria, and translation strategies
Research output: Contribution to journal › Review › Research › peer-review