- Published
Efficient Pulmonary Delivery of siRNA Using Lipid-polymer Hybrid Nanoparticles (LPNs): A quality-by-design approach for highly systematic optimization of LPNs
Thanki, K., Zeng, X., Justesen, S., Tejlmann, S., Falkenberg, E., Nielsen, Hanne Mørck, Franzyk, Henrik & Foged, Camilla, 2017.Research output: Contribution to conference › Poster › Research
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Mechanistic profiling of the release kinetics of siRNA from lipidoid-polymer hybrid nanoparticles in vitro and in vivo after pulmonary administration
Thanki, K., van Eetvelde, D., Geyer, A., Fraire, J., Hendrix, R., Van Eygen, H., Putteman, E., Sami, H., de Souza Carvalho-Wodarz, C., Franzyk, Henrik, Nielsen, Hanne Mørck, Braeckmans, K., Lehr, C., Ogris, M. & Foged, Camilla, 2019, In: Journal of controlled release : official journal of the Controlled Release Society. 310, p. 82-93Research output: Contribution to journal › Journal article › Research › peer-review
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Preparation, Characterization, and In Vitro Evaluation of Lipidoid-Polymer Hybrid Nanoparticles for siRNA Delivery to the Cytosol
Thanki, K., Zeng, X. & Foged, Camilla, 2019, In: Methods in molecular biology (Clifton, N.J.). 1943, p. 141-152 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Immune Reactions in the Delivery of RNA Interference-Based Therapeutics: Mechanisms and Opportunities
Thanki, K., Falkenberg, E., Gangloff, M. & Foged, Camilla, 31 Aug 2018, Immune Effects of Biopharmaceuticals and Nanomedicine. Bawa, R., Szebeni, J. & Audette, G. (eds.). Pan Stanford, 32 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Formulation of RNA interference-based drugs for pulmonary delivery: challenges and opportunities
Thanki, K., Blum, K. G., Thakur, A., Rose, F. & Foged, Camilla, Oct 2018, In: Therapeutic Delivery. 9, 10, p. 731-749 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Lipid-polymer hybrid nanoparticles (LPNs) for efficient pulmonary delivery of nucleic acids: Lessons learnt from quality-by-design based optimization, immunogenicity studies, in vitro release experiments, in vivo biodistribution and efficacy studies
Thanki, K., Thakur, A., de Groot, A. M., Geyer, A., Fraire, J., Falkenberg, E., Van Eygen, H., Putteman, E., Van Bijnen, D. C. J., Zeng, X., Sami, H., Gehrig, S., Justesen, S., Franzyk, H., Broere, F., van Eden, W., Sijts, A. J. A. M., Ogris, M., Nielsen, H. M., Braeckmans, K. & 1 others, , 2018.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
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Immunological and physical evaluation of the multistage tuberculosis subunit vaccine candidate H56/CAF01 formulated as a spray-dried powder
Thakur, A., Ingvarsson, P. T., Schmidt, S. T., Rose, F., Andersen, P., Christensen, D. & Foged, Camilla, 31 May 2018, In: Vaccine. 36, 23, p. 3331-3339 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Nanoparticles for mucosal vaccine delivery
Thakur, A. & Foged, Camilla, 2020, Nanoengineered Biomaterials for Advanced Drug Delivery. Woodhead Publishing, p. 603-646 44 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Nanoparticles for mucosal vaccine delivery
Thakur, A. & Foged, Camilla, 2020, Nanoengineered Biomaterials for Advanced Drug Delivery. Mozafari, M. (ed.). 1 ed. ElsevierResearch output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Method of manufacturing CAF®09 liposomes affects immune responses induced by adjuvanted subunit proteins
Thakur, A., Wadhwa, A., Lokras, Abhijeet, Amanda Oest Müllertz, O., Christensen, D., Franzyk, Henrik & Foged, Camilla, 2023, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 189, p. 84-97Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Design of gadoteridol-loaded cationic liposomal adjuvant CAF01 for MRI of lung deposition of intrapulmonary administered particles
Thakur, A., Rose, F., Ansari, S. R., Koch, P., Martini, V., Ovesen, S. L., Quistorff, B., Maritim, S., Hyder, F., Andersen, Peter, Christensen, D., Mori, Yuki & Foged, Camilla, 2019, In: Molecular Pharmaceutics. 16, 11, p. 4725-4737 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Optimizing the design and dosing of dry powder inhaler formulations of the cationic liposome adjuvant CAF®01 for pulmonary immunization
Thakur, A., Xu, Y., Cano-Garcia, G., Feng, S., Rose, F., Gerde, P., Andersen, Peter, Christensen, D. & Foged, Camilla, 2022, In: Frontiers in Drug Delivery. 2, 973599.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Intracellular Pathogens: Host Immunity and Microbial Persistence Strategies
Thakur, A., Mikkelsen, H. & Jungersen, G., 2019, In: Journal of Immunology Research. 2019, 24 p., 1356540.Research output: Contribution to journal › Review › Research › peer-review
- Published
A study on the prevalence of bovine tuberculosis in farmed dairy cattle in Himachal Pradesh
Thakur, A., Sharma, M., Katoch, V. C., Dhar, P. & Katoch, R. C., 1 Dec 2010, In: Veterinary World. 3, 9, p. 408-414 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dual-Isotope SPECT/CT Imaging of the Tuberculosis Subunit Vaccine H56/CAF01: Induction of Strong Systemic and Mucosal IgA and T-Cell Responses in Mice Upon Subcutaneous Prime and Intrapulmonary Boost Immunization
Thakur, A., Rodríguez-Rodríguez, C., Saatchi, K., Rose, F., Esposito, T., Nosrati, Z., Andersen, P., Christensen, D., Häfeli, U. O. & Foged, Camilla, 2018, In: Frontiers in Immunology. 9, 21 p., 2825.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Intrapulmonary (i.pulmon.) Pull Immunization With the Tuberculosis Subunit Vaccine Candidate H56/CAF01 After Intramuscular (i.m.) Priming Elicits a Distinct Innate Myeloid Response and Activation of Antigen-Presenting Cells Than i.m. or i.pulmon. Prime Immunization Alone
Thakur, A., Pinto, F. E., Hansen, Harald S., Andersen, Peter, Christensen, D., Janfelt, Christian & Foged, Camilla, 2020, In: Frontiers in Immunology. 11, p. 803Research output: Contribution to journal › Journal article › Research › peer-review
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Bicontinuous cubic liquid crystalline nanoparticles for oral delivery of Doxorubicin: implications on bioavailability, therapeutic efficacy, and cardiotoxicity
Swarnakar, N. K., Thanki, K. & Jain, S., May 2014, In: Pharmaceutical Research. 31, 5, p. 1219-38 20 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Enhanced antitumor efficacy and counterfeited cardiotoxicity of combinatorial oral therapy using Doxorubicin- and Coenzyme Q10-liquid crystalline nanoparticles in comparison with intravenous Adriamycin
Swarnakar, N. K., Thanki, K. & Jain, S., Aug 2014, In: Nanomedicine: Nanotechnology, Biology and Medicine. 10, 6, p. 1231-41 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mixed micellar system stabilized with saponins for oral delivery of vitamin K
Sun, F., Ye, C., Thanki, K., Leng, D., van Hasselt, P. M., Hennink, W. E. & van Nostrum, C. F., 1 Oct 2018, In: Colloids and Surfaces B: Biointerfaces. 170, p. 521-528 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Simultaneous neutron reflectometry and infrared reflection absorption spectroscopy (IRRAS) study of mixed monolayer reactions at the air-water interface
Skoda, M. W. A., Thomas, B., Hagreen, M., Sebastiani, Federica & Pfrang, C., 2017, In: RSC Advances.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Complementarity of neutron reflectometry and ellipsometry for the study of atmospheric reactions at the air–water interface
Sebastiani, Federica, Campbell, R. A. & Pfrang, C., 2015, In: RSC Adv..Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nighttime oxidation of surfactants at the air–water interface: effects of chain length, head group and saturation
Sebastiani, Federica, Campbell, R. A., Rastogi, K. & Pfrang, C., 7 Mar 2018, In: Atmospheric Chemistry and Physics.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Diffraction studies on natural and model lipid bilayers
Sebastiani, Federica, Harvey, R., Khanniche, S., Artero, J. B., Haertlein, M. & Fragneto, G., 2012, In: European physical journal-Special topics.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Liposome-Based Adjuvants for Subunit Vaccines: Formulation Strategies for Subunit Antigens and Immunostimulators
Schmidt, S. T., Foged, Camilla, Korsholm, K. S., Rades, Thomas & Christensen, D., 10 Mar 2016, In: Pharmaceutics. 8, 1, 22 p., 7.Research output: Contribution to journal › Review › Research › peer-review
- Published
The administration route is decisive for the ability of the vaccine adjuvant CAF09 to induce antigen-specific CD8(+) T-cell responses: The immunological consequences of the biodistribution profile
Schmidt, S. T., Khadke, S., Korsholm, K. S., Perrie, Y., Rades, Thomas, Andersen, P., Foged, Camilla & Christensen, D., 26 Aug 2016, In: Journal of controlled release : official journal of the Controlled Release Society. 239, p. 107-117 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Opportunities and Challenges in the Delivery of mRNA-based Vaccines
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222
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Immunogenicity Testing of Lipidoids In Vitro and In Silico: Modulating Lipidoid-Mediated TLR4 Activation by Nanoparticle Design
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Induction of Cytotoxic T-Lymphocyte Responses Upon Subcutaneous Administration of a Subunit Vaccine Adjuvanted With an Emulsion Containing the Toll-Like Receptor 3 Ligand Poly(I:C)
Research output: Contribution to journal › Journal article › Research › peer-review
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Latest publications
Evolution of the structure of lipid nanoparticles for nucleic acid delivery: From in situ studies of formulation to colloidal stability
Research output: Contribution to journal › Journal article › Research › peer-review
Effect of lipid-polymer hybrid nanoparticles on the biophysical function and lateral structure of pulmonary surfactant: Mechanistic in vitro studies
Research output: Contribution to journal › Journal article › Research › peer-review
Engineering aspects of lipid-based delivery systems: In vivo gene delivery, safety criteria, and translation strategies
Research output: Contribution to journal › Review › Research › peer-review