Vaccine Design and Delivery

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  1. 2021
  2. Published

    Delivery of oligonucleotide-based therapeutics: challenges and opportunities

    Hammond, S. M., Aartsma-Rus, A., Alves, S., Borgos, S. E., Buijsen, R. A. M., Collin, R. W. J., Covello, G., Denti, M. A., Desviat, L. R., Echevarría, L., Foged, C., Gaina, G., Garanto, A., Goyenvalle, A. T., Guzowska, M., Holodnuka, I., Jones, D. R., Krause, S., Lehto, T., Montolio, M. & 2 others, Van Roon-Mom, W. & Arechavala-Gomeza, V., 2021, In: EMBO Molecular Medicine. 13, 4, 23 p., e13243.

    Research output: Contribution to journal › Review › Research › peer-review

  3. Published

    Engineering of Solid Dosage Forms of siRNA-Loaded Lipidoid-Polymer Hybrid Nanoparticles Using a Quality-by-Design Approach

    Lokras, Abhijeet, Foged, Camilla & Thakur, A., 2021, Design and Delivery of SiRNA Therapeutics. Ditzel, H. J., Tuttolomondo, M. & Kauppinen, S. (eds.). Humana Press, p. 137-157 (Methods in Molecular Biology, Vol. 2282).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  4. Published

    Rational Vaccine Design in Times of Emerging Diseases: The Critical Choices of Immunological Correlates of Protection, Vaccine Antigen and Immunomodulation

    Schijns, V., Majhen, D., Van Der Ley, P., Thakur, A., Summerfield, A., Berisio, R., Nativi, C., Fernández-tejada, A., Álverez-dominguez, C., Gizurarson, S., Zamyatina, A., Molinaro, A., Rosano, C., Jakopin, Ž., Gursel, I. & Mcclean, S., 2021, In: Pharmaceutics. 13, 4, 29 p., 501.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Adsorption of protein antigen to the cationic liposome adjuvant CAF®01 is required for induction of Th1 and Th17 responses but not for antibody induction

    Wørzner, K., Hvannastein, J., Tandrup Schmidt, S., Foged, Camilla, Rosenkrands, I., Kristian Pedersen, G. & Christensen, D., 2021, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 165, p. 293-305

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Inhaled RNA Therapeutics for Obstructive Airway Diseases: Recent Advances and Future Prospects

    Xu, You, Thakur, A., Zhang, Y. & Foged, Camilla, 2021, In: Pharmaceutics. 13, 2, 35 p., 77.

    Research output: Contribution to journal › Review › Research › peer-review

  7. 2022
  8. Published

    Polysaccharide and monosaccharide guided liver delivery of Sorafenib Tosylate: A nano-strategic approach and comparative assessment of hepatospecificity

    Dhawan, V., Lokras, Abhijeet, Joshi, G., Marwah, M., Venkatraman, M., Mohanty, B., Darshan, K., Chaudhari, P., Warawdekar, U., Saraf, M. & Nagarsenker, M., 2022, In: International Journal of Pharmaceutics. 625, 122039.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    COVID-19: Hvem skal nu vaccineres og hvorfor? Professor giver overblikket: Hvor godt virker vaccinerne? Hvem har især gavn af dem? Og hvad ved vi om bivirkningerne? Professor i vaccinedesign guider dig.

    Foged, Camilla, 16 Sep 2022, In: ForskerZonen. 16.09.2022

    Research output: Contribution to journal › Journal article › Research

  10. Published

    COVID-19: Hvordan sikrer vi, at vores vacciner virker mod de nyeste varianter? Når virus muterer, må vi tilpasse vores vacciner. Hvordan sker det i praksis? Og behøver en vaccine overhovedet være tilpasset den seneste variant for at virke?

    Foged, Camilla, 19 Sep 2022, In: ForskerZonen. 19.09.2022

    Research output: Contribution to journal › Journal article › Communication

  11. Published

    Grand Challenges in Vaccine Delivery: Lessons Learned From the COVID-19 Vaccine Rollout

    Foged, Camilla, 2022, In: Frontiers in Drug Delivery. 2, 4 p., 964298.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    A bifunctional enzyme of Legionella that distinctly regulates phosphoribosyl ubiquitination of the SidE family effectors

    Jiao, J., Ouyang, X., Xu, Y. & Xiong, X., 2022, In: Journal of Translational Internal Medicine. 10, 2, p. 86-88

    Research output: Contribution to journal › Editorial › Research › peer-review

  13. Published

    Simultaneous quantification of multiple RNA cargoes co-loaded into nanoparticle-based delivery systems

    Lokras, Abhijeet, Chakravarty, A., Rades, Thomas, Christensen, D., Franzyk, Henrik, Thakur, A. & Foged, Camilla, 2022, In: International Journal of Pharmaceutics. 626, 13 p., 122171.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Adjuvants, immunomodulators, and adaptogens

    Milicic, A., Reinke, S., Fergusson, J., Lindblad, E. B., Hu, K., Thakur, A., Corby, G., Longet, S., Górska, S., Razim, A., Morein, B., Luchner, M., Christensen, D., Mrenoshki, S., Ceylan, S. E., Gizurarson, S. & Ugwu, M. C., 2022, Vaccinology and Methods in Vaccine Research. Elsevier, p. 223-280

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  15. Published

    Lipid Nanoparticle-Mediated Delivery of Therapeutic and Prophylactic mRNA: Immune Activation by Ionizable Cationic Lipids

    Ongun, Melike, Lokras, Abhijeet, Foged, Camilla & Thakur, A., 2022, Messenger RNA Therapeutics. Springer, p. 237-255 (RNA Technologies, Vol. 13).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  16. Published

    Optimizing the design and dosing of dry powder inhaler formulations of the cationic liposome adjuvant CAF®01 for pulmonary immunization

    Thakur, A., Xu, Y., Cano-Garcia, G., Feng, S., Rose, F., Gerde, P., Andersen, Peter, Christensen, D. & Foged, Camilla, 2022, In: Frontiers in Drug Delivery. 2, 973599.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Inhalable Composite Microparticles Containing siRNA-Loaded Lipid-Polymer Hybrid Nanoparticles: Saccharides and Leucine Preserve Aerosol Performance and Long-Term Physical Stability

    Xu, You, Turan, E. T., Shi, Z., Franzyk, Henrik, Thakur, A. & Foged, Camilla, 2022, In: Frontiers in Drug Delivery. 2, 15 p., 945459.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Leucine improves the aerosol performance of dry powder inhaler formulations of siRNA-loaded nanoparticles

    Xu, Y., Harinck, L., Lokras, Abhijeet, Gerde, P., Selg, E., Sjöberg, C., Franzyk, Henrik, Thakur, A. & Foged, Camilla, 2022, In: International Journal of Pharmaceutics. 621, 14 p., 121758.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. 2023
  20. Published

    Elucidating the nanostructure of small interfering RNA-loaded lipidoid-polymer hybrid nanoparticles

    Aljabbari, Anas Samir Mohammad, Lokras, Abhijeet, Kirkensgaard, Jacob Judas Kain, Rades, Thomas, Franzyk, Henrik, Thakur, A., Zhang, Y. & Foged, Camilla, 2023, In: Journal of Colloid and Interface Science. 633, p. 907-922

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Reconstituted Dry Powder Formulations of ZnO-Adjuvanted Ovalbumin Induce Equivalent Serum Antibody Responses to Ovalbumin Adjuvanted with Alhydrogel® or Cationic Adjuvant Formulation 01 (Caf®01)

    Hellfritzsch, M., Christensen, D., Foged, Camilla, Scherließ, R. & Thakur, A., 2023, 41 p. (SSRN Electronic Journal).

    Research output: Working paper › Preprint › Research

  22. Published

    Reconstituted dry powder formulations of ZnO-adjuvanted ovalbumin induce equivalent antigen specific antibodies but lower T cell responses than ovalbumin adjuvanted with Alhydrogel® or cationic adjuvant formulation 01 (CAF®01)

    Hellfritzsch, M., Christensen, D., Foged, Camilla, Scherließ, R. & Thakur, A., 2023, In: International Journal of Pharmaceutics. 648, 15 p., 123581.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Lipid Nanoparticle-Enabled Intracellular Delivery of Prime Editors

    Herrera-Barrera, M., Gautam, M., Lokras, Abhijeet, Vlasova, K., Foged, Camilla & Sahay, G., 2023, In: The AAPS Journal. 25, 4, 10 p., 65.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Comparative study of lipid nanoparticle-based mRNA vaccine bioprocess with machine learning and combinatorial artificial neural network-design of experiment approach

    Maharjan, R., Hada, S., Eun Lee, J., Han, H., Hyun Kim, K., Jin Seo, H., Foged, Camilla & Hoon Jeong, S., 2023, In: International Journal of Pharmaceutics. 640, 13 p., 123012.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Pulmonary Administration of the Liposome-Based Adjuvant CAF01: Effect of Surface Charge on Mucosal Adjuvant Function

    Müllertz, O. A. O., Andersen, P., Christensen, D., Foged, Camilla & Thakur, A., 2023, In: Molecular Pharmaceutics. 20, 2, p. 953–970

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Malaria biomimetic for tumor targeted drug delivery

    Pihl, J., Clausen, T. M., Zhou, J., Krishnan, N., Ørum-Madsen, M. S., Gustavsson, Tobias, Dagil, Robert, Daugaard, M., Choudhary, Swati, Foged, Camilla, Esko, J. D., Zhang, L., Fang, R. H. & Salanti, Ali, 2023, In: ACS Nano. 17, 14, p. 13500–13509

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Method of manufacturing CAF®09 liposomes affects immune responses induced by adjuvanted subunit proteins

    Thakur, A., Wadhwa, A., Lokras, Abhijeet, Amanda Oest Müllertz, O., Christensen, D., Franzyk, Henrik & Foged, Camilla, 2023, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 189, p. 84-97

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Pulmonary delivery of siRNA-loaded lipid-polymer hybrid nanoparticles: Effect of nanoparticle size

    Wadhwa, A., Bobak, T. R., Bohrmann, L., Geczy, R., Sekar, S., Sathyanarayanan, G., Kutter, Jörg P., Franzyk, Henrik, Foged, Camilla, Saatchi, K. & Häfeli, U. O., 2023, In: OpenNano. 13, 12 p., 100180.

    Research output: Contribution to journal › Journal article › Research › peer-review

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