Toxicology and Drug Metabolism

  1. Published

    Modelling idiopathic intracranial hypertension in rats: contributions of high fat diet and testosterone to intracranial pressure and cerebrospinal fluid production

    Wardman, Jonathan Henry, Jensen, Mette Nyholm, Andreassen, Søren Norge, Styrishave, Bjarne, Wilhjelm, J. E., Sinclair, A. J. & MacAulay, Nanna, 2023, In: Fluids and Barriers of the CNS. 20, 1, 17 p., 44.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Mucoadhesive Electrospun Patch Delivery of Lidocaine to the Oral Mucosa and Investigation of Spatial Distribution in a Tissue Using MALDI-Mass Spectrometry Imaging

    Clitherow, K. H., Murdoch, C., Spain, S. G., Handler, A. M., Colley, H. E., Stie, Mai Bay, Nielsen, Hanne Mørck, Janfelt, Christian, Hatton, P. V. & Jacobsen, Jette, Sep 2019, In: Molecular Pharmaceutics. 16, 9, p. 3948-3956

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Mucoadhesive chitosan- and cellulose derivative-based nanofiber-on-foam-on-film system for non-invasive peptide delivery

    Stie, Mai Bay, Öblom, H., Hansen, Anders Christian Nørgaard, Jacobsen, Jette, Chronakis, I. S., Rantanen, Jukka, Nielsen, Hanne Mørck & Genina, Natalja, 2023, In: Carbohydrate Polymers. 303, 120429.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Nicotinamide and phytochemicals phloroglucinol and syringic acid delay uvr-induced squamous cell carcinoma onset in hairless mice

    Pihl, Celina, Andersen, F., Bjerring, P., Hædersdal, Merete & Lerche, Catharina Margrethe, 2022, In: Anticancer Research. 42, 4, p. 2207-2207

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  5. Published

    Non-aqueous electrophoresis integrated with electrospray ionization mass spectrometry on a thiol-ene polymer-based microchip device

    Lu, N., Petersen, Nickolaj J., Kretschmann, A. C. & Kutter, Jörg P., 2021, In: Analytical and Bioanalytical Chemistry. 413, p. 4195–4205

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Occurrence and risk assessment of antibiotics in water and lettuce in Ghana

    Azanu, D., Styrishave, Bjarne, Darko, G., Weisser, J. J. & Abaidoo, R. C., 1 May 2018, In: Science of the Total Environment. 622-23, p. 293-305

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Occurrence, removal and risk assessment of steroid hormones in two wastewater stabilization pond systems in Morogoro, Tanzania

    Damkjaer, K., Weisser, J. J., Msigala, S. C., Mdegela, R. & Styrishave, Bjarne, Dec 2018, In: Chemosphere. 212, p. 1142-1154

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Optimization of HPLC–MS/MS method for determination of antimalarial adulterants in herbal products

    Mwankuna, C. J., Kiros, F., Mariki, E. E., Mabiki, F. P., Malebo, H. M., Mdegela, R. H. & Styrishave, Bjarne, 2023, In: Analytical Sciences. 39, p. 407-416

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Accepted/In press

    Oral Squamous Cell Carcinoma Lipid Evaluation in Gingiva Tissue Stored in TRIzol via Shotgun Lipidomics and MALDI Mass Spectrometry Imaging

    Bernardo, R. A., de Oliveira Júnior, C. I., Roque, J. V., Costa, N. D. L., Roriz, V. M., Sorgi, C. A., Janfelt, Christian, Vaz, B. G. & Chaves, A. R., 2023, (Accepted/In press) In: Journal of Proteome Research.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Oral administration of quercetin and fisetin potentiates photocarcinogenesis in UVR-exposed hairless mice

    Pihl, Celina, Granborg, J. R., Pinto, F. E., Bjerring, P., Andersen, F., Janfelt, Christian, Hædersdal, Merete & Lerche, Catharina Margrethe, 2024, In: Phytomedicine Plus. 4, 2, 8 p., 100547.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Oral anti-diabetic drugs as endocrine disruptors in vitro - No evidence for additive effects in binary mixtures

    Munkboel, C. H., Hansen, H. S., Jessen, J. B., Johannsen, Malene Louise & Styrishave, Bjarne, 2021, In: Toxicology in Vitro. 70, 12 p., 105007.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Oral intake of bucillamine, carvedilol, metformin, or phenformin does not protect against UVR-induced squamous cell carcinomas in hairless mice

    Pihl, Celina, Bjerring, P., Andersen, F., Hædersdal, Merete & Lerche, Catharina Margrethe, 2024, In: Photochemical and Photobiological Sciences. 23, p. 517-526

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Oral phytochemicals as photoprotectants in UVR exposed hairless mice: A study of hesperidin methyl chalcone, phloroglucinol, and syringic acid

    Pihl, Celina, Bendtsen, K. M. S., Jensen, Henrik Elvang, Andersen, F., Bjerring, P., Hædersdal, Merete & Lerche, Catharina Margrethe, 2023, In: Journal of Photochemistry and Photobiology B: Biology. 246, 112760.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Permeability Barriers for Nicotine and Mannitol in Porcine Buccal. Mucosa Studied by High-Resolution MALDI Mass Spectrometry Imaging

    Marxen, E., Jacobsen, Jette, Hyrup, B. & Janfelt, Christian, 5 Feb 2018, In: Molecular Pharmaceutics. 15, 2, p. 519-526

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Phototesting in erythropoietic protoporphyria trials: A systematic review

    Heerfordt, I. M., Philipsen, P. A., Lerche, Catharina Margrethe & Wulf, H. C., 2023, In: Experimental Dermatology. 32, 7, p. 1042-1047

    Research output: Contribution to journalReviewResearchpeer-review

  16. Published

    Protection against visible light by dihydroxyacetone in erythropoietic protoporphyria

    Heerfordt, I. M., Philipsen, P. A., Lerche, Catharina Margrethe & Wulf, H. C., 2023, In: Photodiagnosis and Photodynamic Therapy. 41, 5 p., 103302.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Quantification of Urinary Thymidine Dimers in Volunteers After Ultraviolet Radiation Using a New UPLC-MS/MS-based Method

    Lerche, Catharina Margrethe, Philipsen, P. A., Hermansson, S., Heydenreich, J. & Wulf, H. C., 2022, In: Anticancer Research. 42, 10, p. 5069-5076

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Quantifying urinary thymine dimers based on LC-MS/MS

    Lerche, Catharina Margrethe, Philipsen, P. A., Hermansson, S., Heydenreich, J. & Wulf, H. C., 2022, In: Anticancer Research. 42, 4, p. 2204-2204 22.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  19. Published

    Quantitative MALDI mass spectrometry imaging for exploring cutaneous drug delivery of tofacitinib in human skin

    Handler, A. M., Pedersen, G. P., Nielsen, K. T., Janfelt, Christian, Pedersen, A. J. & Clench, M. R., 2021, In: European Journal of Pharmaceutics and Biopharmaceutics. 159, p. 1-10 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Quantitative Mass Spectrometry Imaging of Bleomycin in Skin Using a Mimetic Tissue Model for Calibration

    Traberg, A., Pinto, F. E., Hansen, Anders Christian Nørgaard, Hædersdal, Merete, Lerche, Catharina Margrethe & Janfelt, Christian, 2022, In: Pharmaceuticals. 15, 12, 15 p., 1583.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Quinolizidine alkaloids are transported to seeds of bitter narrow-leafed lupin

    Otterbach, S. L., Yang, T., Kato, L., Janfelt, Christian & Geu-Flores, Fernando, 15 Oct 2019, In: Journal of Experimental Botany. 70, 20, p. 5799-5808

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Repeated exposure to fractional CO2 laser delays squamous cell carcinoma formation and prevents clinical and subclinical photodamage visualized by line-field confocal optical coherence tomography and histology

    Olesen, U. H., Jacobsen, K., Lerche, Catharina Margrethe & Hædersdal, Merete, 2023, In: Lasers in Surgery and Medicine. 55, 1, 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Reservoir of Antibiotic Residues and Resistant Coagulase Negative Staphylococci in a Healthy Population in the Greater Accra Region, Ghana

    Bekoe, S. O., Hane-Weijman, S., Trads, S. L., Orman, E., Opintan, J., Hansen, M., Frimodt-Møller, N. & Styrishave, Bjarne, 2022, In: Antibiotics. 11, 1, 12 p., 119.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Screening novel CNS drug candidates for P-glycoprotein interactions using the cell line iP-gp: In vitro efflux ratios from iP-gp and MDCK-MDR1 monolayers compared to brain distribution data from mice

    Ozgür, Burak, Saaby, Lasse, Janfelt, Christian, Langthaler, K., Eneberg, E., Jacobsen, A., Badolo, L., Montanari, D. & Larsen, Birger Brodin, 2021, In: European Journal of Pharmaceutics and Biopharmaceutics. 169, p. 211-219

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Sertraline Suppresses Testis and Adrenal Steroid Production and Steroidogenic Gene Expression While Increasing LH in Plasma of Male Rats Resulting in Compensatory Hypogonadism

    Munkboel, C. H., Larsen, L. W., Weisser, J. J., Kristensen, D. M. & Styrishave, Bjarne, Jun 2018, In: Toxicological Sciences. 163, 2, p. 609-619

    Research output: Contribution to journalJournal articleResearchpeer-review