Toxicology and Drug Metabolism

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  1. 2021
  2. Published

    Keratinocyte Carcinoma and Photoprevention: The Protective Actions of Repurposed Pharmaceuticals, Phytochemicals and Vitamins

    Pihl, Celina, Togsverd-Bo, K., Andersen, F., Hædersdal, Merete, Bjerring, P. & Lerche, Catharina Margrethe, 2021, In: Cancers. 13, 15, 29 p., 3684.

    Research output: Contribution to journal › Review › Research › peer-review

  3. Published

    Non-aqueous electrophoresis integrated with electrospray ionization mass spectrometry on a thiol-ene polymer-based microchip device

    Lu, N., Petersen, Nickolaj J., Kretschmann, A. C. & Kutter, Jörg P., 2021, In: Analytical and Bioanalytical Chemistry. 413, p. 4195–4205

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Oral anti-diabetic drugs as endocrine disruptors in vitro - No evidence for additive effects in binary mixtures

    Munkboel, C. H., Hansen, H. S., Jessen, J. B., Johannsen, Malene Louise & Styrishave, Bjarne, 2021, In: Toxicology in Vitro. 70, 12 p., 105007.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Quantitative MALDI mass spectrometry imaging for exploring cutaneous drug delivery of tofacitinib in human skin

    Handler, A. M., Pedersen, G. P., Nielsen, K. T., Janfelt, Christian, Pedersen, A. J. & Clench, M. R., 2021, In: European Journal of Pharmaceutics and Biopharmaceutics. 159, p. 1-10 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Screening novel CNS drug candidates for P-glycoprotein interactions using the cell line iP-gp: In vitro efflux ratios from iP-gp and MDCK-MDR1 monolayers compared to brain distribution data from mice

    Ozgür, Burak, Saaby, Lasse, Janfelt, Christian, Langthaler, K., Eneberg, E., Jacobsen, A., Badolo, L., Montanari, D. & Larsen, Birger Brodin, 2021, In: European Journal of Pharmaceutics and Biopharmaceutics. 169, p. 211-219

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Tumor Clearance and Immune Cell Recruitment in UV-Induced Murine Squamous Cell Carcinoma Exposed to Ablative Fractional Laser and Imiquimod Treatment

    Fontenete, S., Lerche, Catharina Margrethe, Paasch, U., Perez-Moreno, Mirna, Olesen, U. H. & Hædersdal, Merete, 2021, In: Lasers in Surgery and Medicine. 53, 9, p. 1227-1237 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Visualization of penetration of topical antifungal drug substances through mycosis-infected nails by matrix assisted laser desorption ionization mass spectrometry imaging (MALDI-MSI)

    Joly-Tonetti, N., Pinto, F. E., Bagger, C., Osman-Ponchet, H. & Janfelt, Christian, 2021, In: Journal of the American Academy of Dermatology. 85, 3, p. AB191-AB191 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  9. Published

    Visualizing the Journey of Fenofibrate through the Rat Gastrointestinal Tract by Matrix-Assisted Laser Desorption/Ionization-Mass Spectrometry Imaging

    Strindberg, S., Plum, J., Bagger, C., Janfelt, Christian & Mullertz, Anette , 2021, In: Molecular Pharmaceutics. 18, 6, p. 2189–2197

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. 2020
  11. Published

    A thiol-ene microfluidic device enabling continuous enzymatic digestion and electrophoretic separation as front-end to mass spectrometric peptide analysis

    Lu, N., Sticker, Drago, Kretschmann, A., Petersen, Nickolaj J. & Kutter, Jörg P., Jun 2020, In: Analytical and Bioanalytical Chemistry. 412, 15, p. 3559-3571 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Antibiotic Uptake by Plant Model

    Azanu, D., Jorgensen, S. E., Darko, G., Styrishave, Bjarne & Abaidoo, R. C., 2020, In: Environmental Modeling & Assessment. 25, 4, p. 545-553 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Detection and quantification of antibiotic residues in urine samples of healthy individuals from rural and urban communities in Ghana using a validated SPE-LC-MS/MS method

    Bekoe, S. O., Orman, E., Asare-Nkansah, S., Sorensen, A. M. L., Bjorklund, E., Adosraku, R. K., Hansen, M. & Styrishave, Bjarne, 2020, In: SN Applied Sciences. 2, 11, 11 p., 1903.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Electrospun α-lactalbumin nanofibers for site-specific and fast-onset delivery of nicotine in the oral cavity: an in vitro, ex vivo and tissue spatial distribution study

    Kalouta, Kleopatra, Stie, Mai Bay, Janfelt, Christian, Chronakis, I. S., Jacobsen, Jette, Nielsen, Hanne Mørck & Foderà, Vito, 2020, In: Molecular Pharmaceutics. 17, 11, p. 4189-4200

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Exposure of consumers to substandard antibiotics from selected authorised and unauthorised medicine sales outlets in Ghana

    Bekoe, S. O., Ahiabu, M. A., Orman, E., Tersbøl, Britt Pinkowski, Adosraku, R. K., Hansen, M., Frimodt-Møller, N. & Styrishave, Bjarne, 2020, In: Tropical Medicine and International Health. 25, 8, p. 962-975 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Intrapulmonary (i.pulmon.) Pull Immunization With the Tuberculosis Subunit Vaccine Candidate H56/CAF01 After Intramuscular (i.m.) Priming Elicits a Distinct Innate Myeloid Response and Activation of Antigen-Presenting Cells Than i.m. or i.pulmon. Prime Immunization Alone

    Thakur, A., Pinto, F. E., Hansen, Harald S., Andersen, Peter, Christensen, D., Janfelt, Christian & Foged, Camilla, 2020, In: Frontiers in Immunology. 11, p. 803

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    MALDI mass spectrometry imaging as a complementary analytical method for improved skin distribution analysis of drug molecule and excipients

    Handler, A. M., Fallah, M., Just Pedersen, A., Pommergaard Pedersen, G., Troensegaard Nielsen, K. & Janfelt, Christian, 2020, In: International Journal of Pharmaceutics. 590, 119949.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Matrix-Assisted Laser Desorption/Ionization-Mass Spectrometry Imaging of Metabolites during Sorghum Germination

    Montini, L., Crocoll, C., Gleadow, R. M., Motawia, M. S., Janfelt, Christian & Bjarnholt, Nanna, 2020, In: Plant Physiology. 183, 3, p. 925-942 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Measuring and validating concentrations of steroid hormones in the skin of bottlenose dolphins (Tursiops truncatus)

    Bechshoft, T., Wright, A. J., Styrishave, Bjarne & Houser, D., 2020, In: Conservation Physiology. 8, 1, 13 p., 032.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Microcystins and Microcystis aeruginosa PCC7806 extracts modulate steroidogenesis differentially in the human H295R adrenal model

    Mallia, V., Verhaegen, S., Styrishave, Bjarne, Eriksen, G. S., Johannsen, Malene Louise, Ropstad, E. & Uhlig, S., 2020, In: PLoS ONE. 15, 12, 18 p., 0244000.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Sled Dogs as Sentinel Species for Monitoring Arctic Ecosystem Health

    Sonne, C., Letcher, R. J., Jenssen, B. M., Desforges, J., Eulaers, I., Andersen-Ranberg, E., Gustavson, K., Bossi, R., Styrishave, Bjarne, Sinding, Mikkel Holger Strander & Dietz, R., 2020, Pets as Sentinels, Forecasters and Promoters of Human Health. Pastorinho, M. R. & Sousa, A. C. A. (eds.). Springer, p. 21-45 25 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  22. Published

    The plasma pharmacokinetics of fosfomycin and metronidazole after intraperitoneal administration in patients undergoing appendectomy for uncomplicated appendicitis

    Fonnes, S., Weisser, J. J., Holzknecht, Barbara Juliane, Arpi, M. & Rosenberg, Jacob, 2020, In: Fundamental and Clinical Pharmacology. 34, 4, p. 504-512 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Visualisation of penetration of topical antifungal drug substances through mycosis-infected nails by matrix-assisted laser desorption ionisation mass spectrometry imaging

    Endringer Pinto, F., Bagger, C., Kunze, G., Joly-Tonetti, N., Thenot, J., Osman-Ponchet, H. & Janfelt, Christian, 2020, In: Mycoses. 63, 8, p. 869-875 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. 2019
  25. Published

    Current state of knowledge on biological effects from contaminants on arctic wildlife and fish

    Dietz, R., Letcher, R. J., Desforges, J-P., Eulaers, I., Sonne, C., Wilson, S., Andersen-Ranberg, E., Basu, N., Barst, B. D., Bustnes, J. O., Bytingsvik, J., Ciesielski, T. M., Drevnick, P. E., Gabrielsen, G., Haarr, A., Hylland, K., Jenssen, B. M., Levin, M., McKinney, M. A., Norregaard, R. D. & 50 others, Pedersen, K. E., Provencher, J., Styrishave, Bjarne, Tartu, S., Aars, J., Ackerman, J. T., Rosing-Asvid, A., Barrett, R., Bignert, A., Borns, E. W., Branigan, M., Braune, B., Bryan, C. E., Dam, M., Eagles-Smith, C. A., Evans, M., Evans, T. J., Fisk, A. T., Gamberg, M., Gustavson, K., Hartman, C. A., Helander, B., Herzog, M. P., Hoekstra, P. F., Houde, M., Hoydal, K., Jackson, A. K., Kucklick, J., Lie, E., Loseto, L., Mallory, M. L., Miljeteig, C., Mosbech, A., Muir, D. C. G., Nielsen, S. T., Peacock, E., Pedro, S., Peterson, S. H., Polder, A., Riget, F. F., Roach, P., Saunes, H., Sinding, M. S., Skaare, J. U., Sondergaard, J., Stenson, G., Stern, G., Treu, G., Schuur, S. S. & Vikingsson, G., 15 Dec 2019, In: Science of the Total Environment. 696, 40 p., 133792.

    Research output: Contribution to journal › Review › Research › peer-review

  26. Published

    Fractional laser-assisted topical delivery of bleomycin quantified by LC-MS and visualized by MALDI mass spectrometry imaging

    Hendel, K. K., Bagger, C., Olesen, U. H., Janfelt, Christian, Hansen, S. H., Hædersdal, Merete & Lerche, C. M., Dec 2019, In: Drug Delivery. 26, 1, p. 244-251 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Quinolizidine alkaloids are transported to seeds of bitter narrow-leafed lupin

    Otterbach, S. L., Yang, T., Kato, L., Janfelt, Christian & Geu-Flores, Fernando, 15 Oct 2019, In: Journal of Experimental Botany. 70, 20, p. 5799-5808

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Mucoadhesive Electrospun Patch Delivery of Lidocaine to the Oral Mucosa and Investigation of Spatial Distribution in a Tissue Using MALDI-Mass Spectrometry Imaging

    Clitherow, K. H., Murdoch, C., Spain, S. G., Handler, A. M., Colley, H. E., Stie, Mai Bay, Nielsen, Hanne Mørck, Janfelt, Christian, Hatton, P. V. & Jacobsen, Jette, Sep 2019, In: Molecular Pharmaceutics. 16, 9, p. 3948-3956

    Research output: Contribution to journal › Journal article › Research › peer-review

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