Toxicology and Drug Metabolism

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  1. 2019
  2. Published

    Developing a predictive in vitro dissolution model based on gastrointestinal fluid characterisation in rats

    Christfort, J. F., Strindberg, S., Plum, J., Hall-Andersen, J., Janfelt, Christian, Nielsen, L. H. & Mullertz, Anette , 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 142, p. 307-314 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Efflux Inhibitor Bicalutamide Increases Oral Bioavailability of the Poorly Soluble Efflux Substrate Docetaxel in Co-Amorphous Anti-Cancer Combination Therapy

    Bohr, A., Nascimento, T. L., Harmankaya, N., Weisser, J. J., Wang, Y., Grohganz, Holger, Rades, Thomas & Löbmann, Korbinian, 2019, In: Molecules. 24, 2, 13 p., 266.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    The classic azole antifungal drugs are highly potent endocrine disruptors in vitro inhibiting steroidogenic CYP enzymes at concentrations lower than therapeutic Cmax

    Munkboel, C. H., Rasmussen, T. B., Elgaard, C., Olesen, M. L. K., Kretschmann, A. C. & Styrishave, Bjarne, 2019, In: Toxicology. 425, 152247.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Three versus five days of pivmecillinam for community-acquired uncomplicated lower urinary tract infection: A randomised, double-blind, placebo-controlled superiority trial

    Jansåker, F., Thønnings, S., Hertz, F. B., Kallemose, T., Værnet, J., Bjerrum, Lars, Benfield, Thomas, Frimodt-Møller, N. & Knudsen, J. D., 2019, In: EClinicalMedicine. 12, p. 62-69 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Visualization of the penetration modifying mechanism of laurocapram by Mass Spectrometry Imaging in buccal drug delivery

    Handler, A. M., Marxen, E., Jacobsen, Jette & Janfelt, Christian, 15 Jan 2019, In: European Journal of Pharmaceutical Sciences. 127, p. 276-281 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    State of knowledge on current exposure, fate and potential health effects of contaminants in polar bears from the circumpolar Arctic

    Routti, H., Atwood, T. C., Bechshoft, T., Boltunov, A., Ciesielski, T. M., Desforges, J., Dietz, R., Gabrielsen, G., Jenssen, B. M., Letcher, R. J., McKinney, M. A., Morris, A. D., Riget, F. F., Sonne, C., Styrishave, Bjarne & Tartu, S., 10 May 2019, In: Science of the Total Environment. 664, p. 1063-1083

    Research output: Contribution to journal › Review › Research › peer-review

  8. Published

    Enantioselective mixture toxicity of the azole fungicide imazalil with the insecticide Α-cypermethrin in Chironomus riparius: Investigating the importance of toxicokinetics and enzyme interactions

    Kuhlmann, J., Kretschmann, A. C., Bester, K., Bollmann, U. E., Dalhoff, K. & Cedergreen, Nina, 1 Jun 2019, In: Chemosphere. 225, p. 166-173

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Mucoadhesive Electrospun Patch Delivery of Lidocaine to the Oral Mucosa and Investigation of Spatial Distribution in a Tissue Using MALDI-Mass Spectrometry Imaging

    Clitherow, K. H., Murdoch, C., Spain, S. G., Handler, A. M., Colley, H. E., Stie, Mai Bay, Nielsen, Hanne Mørck, Janfelt, Christian, Hatton, P. V. & Jacobsen, Jette, Sep 2019, In: Molecular Pharmaceutics. 16, 9, p. 3948-3956

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Quinolizidine alkaloids are transported to seeds of bitter narrow-leafed lupin

    Otterbach, S. L., Yang, T., Kato, L., Janfelt, Christian & Geu-Flores, Fernando, 15 Oct 2019, In: Journal of Experimental Botany. 70, 20, p. 5799-5808

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Fractional laser-assisted topical delivery of bleomycin quantified by LC-MS and visualized by MALDI mass spectrometry imaging

    Hendel, K. K., Bagger, C., Olesen, U. H., Janfelt, Christian, Hansen, S. H., Hædersdal, Merete & Lerche, C. M., Dec 2019, In: Drug Delivery. 26, 1, p. 244-251 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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