Toxicology and Drug Metabolism

  1. 2023
  2. Published

    Leaves of Cannabis sativa and their trichomes studied by DESI and MALDI mass spectrometry imaging for their contents of cannabinoids and flavonoids

    Lorensen, Marcus Daniel B B, Hayat, S. Y., Wellner, N., Bjarnholt, Nanna & Janfelt, Christian, 2023, In: Phytochemical Analysis. 34, 3, p. 269-279

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Spatial localization of monoterpenoid indole alkaloids in Rauvolfia tetraphylla by high resolution mass spectrometry imaging

    Lorensen, Marcus Daniel B B, Bjarnholt, Nanna, St-Pierre, B., Heinicke, S., Courdavault, V., O'Connor, S. & Janfelt, Christian, 2023, In: Phytochemistry. 209, 15 p., 113620.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Tissue-specific stilbene accumulation is an early response to wounding/grafting as revealed by using spatial and temporal metabolomics

    Loupit, G., Fonayet, J. V., Lorensen, Marcus Daniel B B, Franc, C., De Revel, G., Janfelt, Christian & Cookson, S. J., 2023, In: Plant Cell and Environment. 46, 12, p. 3871-3886

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Comparison of global DNA methylation analysis by whole genome bisulfite sequencing and the Infinium Mouse Methylation BeadChip using fresh and fresh-frozen mouse epidermis

    Meyer, Olivia Luxford, Andersen, M. M., Børsting, Claus, Morling, Niels, Wulf, H. C., Philipsen, P. A., Lerche, Catharina Margrethe & Andersen, Jeppe Dyrberg, 2023, In: Epigenetics. 18, 1, 10 p., 2144574 .

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Optimization of HPLC–MS/MS method for determination of antimalarial adulterants in herbal products

    Mwankuna, C. J., Kiros, F., Mariki, E. E., Mabiki, F. P., Malebo, H. M., Mdegela, R. H. & Styrishave, Bjarne, 2023, In: Analytical Sciences. 39, p. 407-416

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Thin Layer Chromatographic Method for Detection of Conventional Drug Adulterants in Herbal Products

    Mwankuna, C. J., Mariki, E. E., Mabiki, F. P., Malebo, H. M., Styrishave, Bjarne & Mdegela, R. H., 2023, In: Separations. 10, 1, 10 p., 23.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Repeated exposure to fractional CO2 laser delays squamous cell carcinoma formation and prevents clinical and subclinical photodamage visualized by line-field confocal optical coherence tomography and histology

    Olesen, U. H., Jacobsen, K., Lerche, Catharina Margrethe & Hædersdal, Merete, 2023, In: Lasers in Surgery and Medicine. 55, 1, 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Oral phytochemicals as photoprotectants in UVR exposed hairless mice: A study of hesperidin methyl chalcone, phloroglucinol, and syringic acid

    Pihl, Celina, Bendtsen, K. M. S., Jensen, Henrik Elvang, Andersen, F., Bjerring, P., Hædersdal, Merete & Lerche, Catharina Margrethe, 2023, In: Journal of Photochemistry and Photobiology B: Biology. 246, 112760.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    In Vitro and In Vivo Evaluation of Pellotine: A Hypnotic Lophophora Alkaloid

    Poulie, C. B. M., Chan, C. B., Parka, A., Lettorp, M., Vos, J., Raaschou, A., Pottie, E., Bundgaard, M. S., Sørensen, L. M. E., Cecchi, C. R., Märcher-Rørsted, E., Bach, A., Herth, M. M., Decker, A., Jensen, A. A., Elfving, B., Kretschmann, A. C., Stove, C. P., Kohlmeier, K. A., Cornett, C. & 3 others, Janfelt, Christian, Kornum, Birgitte Rahbek & Kristensen, Jesper Langgaard, 2023, In: ACS Pharmacology & Translational Science. 6, 10, p. 1492-1507

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Elucidating the spatial distribution of organic contaminants and their biotransformation products in amphipod tissue by MALDI- and DESI-MS-imaging

    Raths, J., Pinto, F. E., Janfelt, Christian & Hollender, J., 2023, In: Ecotoxicology and Environmental Safety. 264, 10 p., 115468.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Importance of Dietary Uptake for in Situ Bioaccumulation of Systemic Fungicides Using Gammarus pulex as a Model Organism

    Raths, J., Schnurr, J., Bundschuh, M., Pinto, F. E., Janfelt, Christian & Hollender, J., 2023, In: Environmental Toxicology and Chemistry. 42, 9, p. 1993-2006

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    A New Ellagic Acid Rhamnoside from Synadenium glaucescens and Its Cytotoxicity Evaluation

    Rwegoshora, F., Mabiki, F., Machumi, F., Chacha, M., Styrishave, Bjarne & Cornett, Claus, 2023, In: Chemistry of Natural Compounds. 59, 4, p. 670-674

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Isolation and elucidation of antibacterial compounds from roots and stems of Synadenium glaucescens Pax

    Rwegoshora, F., Msengwa, Z., Mabiki, F., Machumi, F., Chacha, M., Styrishave, Bjarne & Cornett, Claus, 2023, In: East African Journal of Science, Technology and Innovation. 4, 2, 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    The Rauvolfia tetraphylla genome suggests multiple distinct biosynthetic routes for yohimbane monoterpene indole alkaloids

    Stander, E. A., Lehka, B., Carqueijeiro, I., Cuello, C., Hansson, F. G., Jansen, H. J., Dugé De Bernonville, T., Birer Williams, C., Vergès, V., Lezin, E., Lorensen, M. D. B. B., Dang, T. T., Oudin, A., Lanoue, A., Durand, M., Giglioli-Guivarc’h, N., Janfelt, C., Papon, N., Dirks, R. P., O’connor, S. E. & 3 others, Jensen, M. K., Besseau, S. & Courdavault, V., 2023, In: Communications Biology . 6, 1, 19 p., 1197.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Mucoadhesive chitosan- and cellulose derivative-based nanofiber-on-foam-on-film system for non-invasive peptide delivery

    Stie, Mai Bay, Öblom, H., Hansen, Anders Christian Nørgaard, Jacobsen, Jette, Chronakis, I. S., Rantanen, Jukka, Nielsen, Hanne Mørck & Genina, Natalja, 2023, In: Carbohydrate Polymers. 303, 120429.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Modelling idiopathic intracranial hypertension in rats: contributions of high fat diet and testosterone to intracranial pressure and cerebrospinal fluid production

    Wardman, Jonathan Henry, Jensen, Mette Nyholm, Andreassen, Søren Norge, Styrishave, Bjarne, Wilhjelm, J. E., Sinclair, A. J. & MacAulay, Nanna, 2023, In: Fluids and Barriers of the CNS. 20, 1, 17 p., 44.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. 2022
  19. Published

    Reservoir of Antibiotic Residues and Resistant Coagulase Negative Staphylococci in a Healthy Population in the Greater Accra Region, Ghana

    Bekoe, S. O., Hane-Weijman, S., Trads, S. L., Orman, E., Opintan, J., Hansen, M., Frimodt-Møller, N. & Styrishave, Bjarne, 2022, In: Antibiotics. 11, 1, 12 p., 119.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    In vivo dermal delivery of bleomycin with electronic pneumatic injection: drug visualization and quantification with mass spectrometry

    Bik, L., van Doorn, M., Hansen, Anders Christian Nørgaard, Janfelt, Christian, Olesen, U. H., Hædersdal, Merete, Lerche, Catharina Margrethe & Hendel, K., 2022, In: Expert Opinion on Drug Delivery. 19, 2, p. 213-219

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Smooth muscle ATP-sensitive potassium channels mediate migraine-relevant hypersensitivity in mouse models

    Christensen, S. L., Rasmussen, Rikke Holm, Cour, S. L., Ernstsen, C., Hansen, Thomas Folkmann, Kogelman, L. J. A., Lauritzen, S. P., Guzaite, G., Styrishave, Bjarne, Janfelt, Christian, Christensen, Søren Tvorup, Aziz, Q., Tinker, A., Jansen-Olesen, I., Olesen, Jes & Kristensen, D. M., 2022, In: Cephalalgia. 42, 2, p. 93-107

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Anti-Newcastle Disease Virus activity of 3β and 3α Friedelanol Triterpenoids from the leaves of Synadenium glaucescens Pax

    Credo, D., Mabiki, F. P., Machumi, F., Chacha, M., Cornett, Claus & Styrishave, Bjarne, 2022, In: Tropical Biomedicine. 39, 2, p. 257-264 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    A one-time pneumatic jet-injection of 5-fluorouracil and triamcinolone acetonide for treatment of hypertrophic scars: A blinded randomized controlled trial

    Erlendsson, A. M., Rosenberg, L. K., Lerche, Catharina Margrethe, Togsverd-Bo, K., Wiegell, Stine Regin, Karmisholt, Katrine Elisabeth, Philipsen, P. A., Hansen, Anders Christian Nørgaard, Janfelt, Christian, Holmes, J., Rossi, A. & Hædersdal, Merete, 2022, In: Lasers in Surgery and Medicine. 54, 5, p. 663-671

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Mass spectrometry imaging of oligosaccharides following in situ enzymatic treatment of maize kernels

    Granborg, J. R., Kaasgaard, S. G. & Janfelt, Christian, 2022, In: Carbohydrate Polymers. 275, 10 p., 118693.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Mass spectrometry imaging in drug distribution and drug metabolism studies: Principles, applications and perspectives

    Granborg, J. R., Handler, A. M. & Janfelt, Christian, 2022, In: Trends in Analytical Chemistry. 146, 13 p., 116482.

    Research output: Contribution to journalReviewResearchpeer-review

  26. Published

    Cimetidine for erythropoietic protoporphyria

    Heerfordt, I. M., Lerche, Catharina Margrethe & Wulf, H. C., 2022, In: Photodiagnosis and Photodynamic Therapy. 38, 5 p., 102793.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Detection of cutaneous malignant melanoma using RNA sampled by tape strips: A study protocol

    Heerfordt, I. M., Andersen, Jeppe Dyrberg, Philipsen, P. A., Langhans, L., Tvedebrink, Torben, Schmidt, G., Poulsen, T., Lerche, Catharina Margrethe, Morling, Niels & Wulf, H. C., 2022, In: PLoS ONE. 17, 9 , 11 p., e0274413.

    Research output: Contribution to journalJournal articleResearchpeer-review