Selection of suitable drug and excipient candidates to prepare glass solutions by melt extrusion for immediate release oral formulations

Research output: Contribution to journal › Review › Research › peer-review

Standard

Selection of suitable drug and excipient candidates to prepare glass solutions by melt extrusion for immediate release oral formulations. / Forster, Angus; Rades, Thomas; Hempenstall, John.

In: Pharmaceutical Technology Europe, Vol. 14, No. 10, 01.10.2002, p. 27-28+31.

Research output: Contribution to journal › Review › Research › peer-review

Harvard

Forster, A, Rades, T & Hempenstall, J 2002, 'Selection of suitable drug and excipient candidates to prepare glass solutions by melt extrusion for immediate release oral formulations', Pharmaceutical Technology Europe, vol. 14, no. 10, pp. 27-28+31.

APA

Forster, A., Rades, T., & Hempenstall, J. (2002). Selection of suitable drug and excipient candidates to prepare glass solutions by melt extrusion for immediate release oral formulations. Pharmaceutical Technology Europe, 14(10), 27-28+31.

Vancouver

Forster A, Rades T, Hempenstall J. Selection of suitable drug and excipient candidates to prepare glass solutions by melt extrusion for immediate release oral formulations. Pharmaceutical Technology Europe. 2002 Oct 1;14(10):27-28+31.

Author

Forster, Angus ; Rades, Thomas ; Hempenstall, John. / Selection of suitable drug and excipient candidates to prepare glass solutions by melt extrusion for immediate release oral formulations. In: Pharmaceutical Technology Europe. 2002 ; Vol. 14, No. 10. pp. 27-28+31.

Bibtex

@article{d70c111d8be743b8bf15f978b7cadbd5,
title = "Selection of suitable drug and excipient candidates to prepare glass solutions by melt extrusion for immediate release oral formulations",
abstract = "Using melt extrusion to prepare glass solutions of poorly water-soluble drugs with hydrophilic excipients offers an exciting and advantageous alternative to existing formulation methods such as spray-drying and co-melting. Investigating potential methods to increase water solubility begins early in drug development. Techniques described in this paper show how only a small quantity of drug can be used to determine its suitability for melt extrusion, allowing the method to be considered at the same time as salt screening and particle size reduction work, and could speed up the formulation process.",
author = "Angus Forster and Thomas Rades and John Hempenstall",
year = "2002",
month = oct,
day = "1",
language = "English",
volume = "14",
pages = "27--28+31",
journal = "Pharmaceutical Technology Europe",
issn = "0164-6826",
publisher = "Advanstar Communications",
number = "10",

}

RIS

TY - JOUR

T1 - Selection of suitable drug and excipient candidates to prepare glass solutions by melt extrusion for immediate release oral formulations

AU - Forster, Angus

AU - Rades, Thomas

AU - Hempenstall, John

PY - 2002/10/1

Y1 - 2002/10/1

N2 - Using melt extrusion to prepare glass solutions of poorly water-soluble drugs with hydrophilic excipients offers an exciting and advantageous alternative to existing formulation methods such as spray-drying and co-melting. Investigating potential methods to increase water solubility begins early in drug development. Techniques described in this paper show how only a small quantity of drug can be used to determine its suitability for melt extrusion, allowing the method to be considered at the same time as salt screening and particle size reduction work, and could speed up the formulation process.

AB - Using melt extrusion to prepare glass solutions of poorly water-soluble drugs with hydrophilic excipients offers an exciting and advantageous alternative to existing formulation methods such as spray-drying and co-melting. Investigating potential methods to increase water solubility begins early in drug development. Techniques described in this paper show how only a small quantity of drug can be used to determine its suitability for melt extrusion, allowing the method to be considered at the same time as salt screening and particle size reduction work, and could speed up the formulation process.

UR - http://www.scopus.com/inward/record.url?scp=0036794236&partnerID=8YFLogxK

M3 - Review

AN - SCOPUS:0036794236

VL - 14

SP - 27-28+31

JO - Pharmaceutical Technology Europe

JF - Pharmaceutical Technology Europe

SN - 0164-6826

IS - 10

ER -

ID: 299430190