Solid State Pharmaceutics

  1. 2024
  2. Published

    Acheta domesticus: A Natural Source of Anti-Skin-Aging Ingredients for Cosmetic Applications

    Yeerong, K., Chantawannakul, P., Anuchapreeda, S., Rades, Thomas, Mullertz, Anette & Chaiyana, W., 2024, In: Pharmaceuticals. 17, 3, 20 p., 346.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Analysis of stabilization mechanisms in β-lactoglobulin-based amorphous solid dispersions by experimental and computational approaches

    Zhuo, Xuezhi, Foderà, Vito, Larsson, P., Schaal, Z., Bergström, C. A. S., Löbmann, Korbinian & Kabedev, A., 2024, In: European Journal of Pharmaceutical Sciences. 192, 13 p., 106639.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Coaxial electrospinning of polycaprolactone: A design of experiments approach

    Gürtler, Anna-Lena, Linseisen, I., Grohganz, Holger & Heinz, Andrea, 2024, In: European Polymer Journal. 208, 11 p., 112886.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Comparison of the liquisolid technique and co-milling for loading of a poorly soluble drug in inorganic porous excipients

    Ogadah, C. U., Mrštná, K., Matysová, L., Mullertz, Anette , Rades, Thomas, Niederquell, A., Šklubalová, Z. & Vraníková, B., 2024, In: International Journal of Pharmaceutics. 650, 10 p., 123702.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Destabilization of Indomethacin-Paracetamol Co-Amorphous Systems by Mechanical Stress

    Di, Rong, Grohganz, Holger & Rades, Thomas, 2024, In: Pharmaceutics. 16, 15 p., 67.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Effect of Drug Loading in Mesoporous Silica on Amorphous Stability and Performance

    Bavnhøj, C. G., Knopp, Matthias Manne & Löbmann, Korbinian, 2024, In: Pharmaceutics. 16, 2, 11 p., 163.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Exploring the effect of protein secondary structure on the solid state and physical stability of protein-based amorphous solid dispersions

    Zhuo, Xuezhi, Ochner, J., Leng, D., Foderà, Vito & Löbmann, Korbinian, 2024, In: European Journal of Pharmaceutics and Biopharmaceutics. 198, 8 p., 114274.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Indomethacin-omeprazole as therapeutic hybrids? Salt and co-amorphous systems enhancing physicochemical and pharmacological properties

    Carneiro Soares Do Nascimento, A L, Batista Martins, Inês Catarina, Spósito, L., Morais-Silva, G., Duarte, J. L., Rades, Thomas & Chorilli, M., 2024, In: International Journal of Pharmaceutics. 653, 11 p., 123857.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Influence of preparation method and choice of phospholipid on co-amorphization, physical stability, and dissolution behavior of equimolar indomethacin-phospholipid systems: A case study

    Khorami, Keyoomars, Mullertz, Anette & Rades, Thomas, 2024, In: Journal of Drug Delivery Science and Technology. 93, 8 p., 105433.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Influence of water and trehalose on α- and β-relaxation of freeze-dried lysozyme formulations

    Vallaster, B., Engelsing, F. & Grohganz, Holger, 2024, In: European Journal of Pharmaceutics and Biopharmaceutics. 194, p. 1-8

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Investigating the influence of protein secondary structure on the dissolution behavior of β-lactoglobulin-based amorphous solid dispersions

    Zhuo, Xuezhi, Tozzetti, M., Arnous, A., Leng, D., Foderà, Vito & Löbmann, Korbinian, 2024, In: International Journal of Pharmaceutics. 653, 8 p., 123887.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Lipid nanoparticles for local delivery of mRNA to the respiratory tract: Effect of PEG-lipid content and administration route

    Ongun, Melike, Lokras, Abhijeet, Baghel, Saahil Sandeep, Shi, Zhenning, Schmidt, S. T., Franzyk, Henrik, Rades, Thomas, Sebastiani, Federica, Thakur, A. & Foged, Camilla, 2024, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 198, 10 p., 114266.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Molecular interactions of hydrated co-amorphous systems of prilocaine and lidocaine

    Xu, X., Rades, Thomas & Grohganz, Holger, 2024, In: International Journal of Pharmaceutics. 651, 7 p., 123807.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    The interplay between trehalose and dextran as spray drying precursors for cationic liposomes

    Lutta, A., Knopp, Matthias Manne, Tollemeto, M., Pedersen, Gabriel Kristian, Schmidt, S. T., Grohganz, Holger & Hagner Nielsen, L., 2024, In: International Journal of Pharmaceutics. 652, 10 p., 123798.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Use of solid thermolytic salts to facilitate microwave-induced in situ amorphization

    Qiang, W., Zhang, M., Löbmann, Korbinian, McCoy, C. P., Andrews, G. P. & Zhao, M., 2024, In: International Journal of Pharmaceutics. 651, 11 p., 123791.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. 2023
  18. Published

    In vitro-in vivo relationship for amorphous solid dispersions using a double membrane dissolution-permeation setup

    Jørgensen, J. R., Mohr, W., Rischer, M., Sauer, A., Mistry, S., Rades, Thomas & Mullertz, Anette , 2023, In: European Journal of Pharmaceutics and Biopharmaceutics. 188, p. 26-32

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    A Comparative Study between A Protein Based Amorphous Formulation and Other Dissolution Rate Enhancing Approaches: A Case Study with Rifaximin

    Zhuo, Xuezhi, Margrethe Brekstad Kjellin, M., Schaal, Z., Zhang, T., Löbmann, Korbinian & Leng, D., 2023, In: Pharmaceutics. 15, 1, 10 p., 126.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Amorphization of different furosemide polymorphic forms during ball milling: Tracking solid-to-solid phase transformations

    Wang, M., Gong, J., Rades, Thomas & Batista Martins, Inês Catarina, 2023, In: International Journal of Pharmaceutics. 648, 9 p., 123573.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Assessing acute colitis induced by dextran sulfate sodium in rats and its impact on gastrointestinal fluids

    Klitgaard, Mette, Kristensen, M. N., Venkatasubramanian, R., Guerra, Priscila Regina, Jacobsen, Jette, Berthelsen, R., Rades, Thomas & Mullertz, Anette , 2023, In: Drug Delivery and Translational Research. 13, p. 1484–1499

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Co-amorphous systems consisting of indomethacin and the chiral co-former tryptophan: Solid-state properties and molecular mobilities

    Holzapfel, K., Rades, Thomas & Leopold, C. S., 2023, In: International Journal of Pharmaceutics. 636, 12 p., 122840.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Compaction Behavior of Co-Amorphous Systems

    Sørensen, C. M., Rantanen, Jukka & Grohganz, Holger, 2023, In: Pharmaceutics. 15, 3, 12 p., 858.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Considerations on the Kinetic Processes in the Preparation of Ternary Co-Amorphous Systems by Milling

    Wang, Y., Rades, Thomas & Grohganz, Holger, 2023, In: Pharmaceutics. 15, 1, 14 p., 172.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Design of experiments approach on the compaction properties of co-amorphous tablets

    Engelsing, F., Buchart, L. & Grohganz, Holger, 2023, In: Pharmaceutical Development and Technology. 28, 9, p. 907-914

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Editorial: In honor of Professor Ian Tucker

    Das, S., Rades, Thomas & McDowell, A., 2023, In: International Journal of Pharmaceutics. 638, 2 p., 122762.

    Research output: Contribution to journalEditorialResearchpeer-review

  27. Published

    Electrospun fibers for the treatment of skin diseases

    Gürtler, Anna-Lena, Rades, Thomas & Heinz, Andrea, 2023, In: Journal of controlled release : official journal of the Controlled Release Society. 363, p. 621-640

    Research output: Contribution to journalReviewResearchpeer-review

  28. Published

    Elucidating the nanostructure of small interfering RNA-loaded lipidoid-polymer hybrid nanoparticles

    Aljabbari, Anas Samir Mohammad, Lokras, Abhijeet, Kirkensgaard, Jacob Judas Kain, Rades, Thomas, Franzyk, Henrik, Thakur, A., Zhang, Y. & Foged, Camilla, 2023, In: Journal of Colloid and Interface Science. 633, p. 907-922

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Enhancing tabletability of high-dose tablets by tailoring properties of spray-dried insulin particles

    Pedersen, M. D., Megarry, A., Naelapää, K., Rades, Thomas & Pessi, J., 2023, In: International Journal of Pharmaceutics. 631, 8 p., 122526.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Exploring the Solid-State Landscape of Carbamazepine during Dehydration: A Low Frequency Raman Spectroscopy Perspective

    Remoto, P. I. I. I. J. G., Bērziņš, Kārlis, Fraser-Miller, S. J., Korter, T. M., Rades, Thomas, Rantanen, Jukka & Gordon, K. C., 2023, In: Pharmaceutics. 15, 5, 15 p., 1526.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Functionalized calcium carbonate (FCC) as a novel carrier to solidify supersaturated self-nanoemulsifying drug delivery systems (super-SNEDDS)

    Merchant, J., Mullertz, Anette , Rades, Thomas & Bannow, J., 2023, In: European Journal of Pharmaceutics and Biopharmaceutics. 193, p. 198-207

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Influence of Polyvinylpyrrolidone Molecular Weight and Concentration on the Precipitation Inhibition of Supersaturated Solutions of Poorly Soluble Drugs

    Odeh, A. B., El-Sayed, B., Knopp, Matthias Manne, Rades, Thomas & Blaabjerg, L. I., 2023, In: Pharmaceutics. 15, 6, 17 p., 1601.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Interaction of liposomes with bile salts investigated by asymmetric flow field-flow fractionation (AF4): A novel approach for stability assessment of oral drug carriers

    Bohsen, M. S., Tychsen, S. T., Kadhim, A. A. H., Grohganz, Holger, Treusch, A. H. & Brandl, M., 2023, In: European Journal of Pharmaceutical Sciences. 182, 10 p., 106384.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Mechanisms of Drug Solubility Enhancement Induced by β-Lactoglobulin-Based Amorphous Solid Dispersions

    Zhuo, Xuezhi, Sener, Z., Kabedev, A., Zhao, M., Arnous, A., Leng, D., Foderà, Vito & Löbmann, Korbinian, 2023, In: Molecular Pharmaceutics. 20, 10, p. 5206–5213

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Preparation of Co-Amorphous Levofloxacin Systems for Pulmonary Application

    Gabelmann, A., Lehr, C. M. & Grohganz, Holger, 2023, In: Pharmaceutics. 15, 6, 15 p., 1574.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Recent Advances in Co-Former Screening and Formation Prediction of Multicomponent Solid Forms of Low Molecular Weight Drugs

    Deng, Y., Liu, S., Jiang, Y., Batista Martins, Inês Catarina & Rades, Thomas, 2023, In: Pharmaceutics. 15, 9, 33 p., 2174.

    Research output: Contribution to journalReviewResearchpeer-review

  37. Published

    Solid-state analysis for pharmaceuticals: Pathways to feasible and meaningful analysis

    Rantanen, Jukka, Rades, Thomas & Strachan, C., 2023, In: Journal of Pharmaceutical and Biomedical Analysis. 236, 7 p., 115649.

    Research output: Contribution to journalReviewResearchpeer-review

  38. Published

    Stability and intrinsic dissolution of vacuum compression molded amorphous solid dispersions of efavirenz

    Jørgensen, J. R., Mohr, W., Rischer, M., Sauer, A., Mistry, S., Mullertz, Anette & Rades, Thomas, 2023, In: International Journal of Pharmaceutics. 632, 8 p., 122564.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    The Influence of Gastrointestinal Biomolecules on Solid-State Transformations in Pharmaceutical Particulates

    Aljabbari, Anas Samir Mohammad, Kihara, Shinji, Rades, Thomas, Boyd, Ben & Bērziņš, Kārlis, 2023, In: Molecular Pharmaceutics. 20, 8, p. 4297-4306

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    The biomolecular gastrointestinal corona in oral drug delivery

    Aljabbari, Anas Samir Mohammad, Kihara, Shinji, Rades, Thomas & Boyd, Ben, 2023, In: Journal of controlled release : official journal of the Controlled Release Society. 363, p. 536-549

    Research output: Contribution to journalReviewResearchpeer-review

  41. Published

    The effects of surfactants on the performance of polymer-based microwave-induced in situ amorphization

    Qiang, W., Löbmann, Korbinian, McCoy, C. P., Andrews, G. P. & Zhao, M., 2023, In: International Journal of Pharmaceutics. 630, 17 p., 122426.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Thermal investigation on hydrated co-amorphous systems of nicotinamide and prilocaine

    Xu, X., Rades, Thomas & Grohganz, Holger, 2023, In: European Journal of Pharmaceutics and Biopharmaceutics. 186, p. 1-6

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Unveiling polyamorphism and polyamorphic interconversions in pharmaceuticals: the peculiar case of hydrochlorothiazide

    Batista Martins, Inês Catarina, Larsen, A. S., Madsen, Anders Østergaard, Aalling-Frederiksen, Olivia, Correia, A., Jensen, Kirsten Marie Ørnsbjerg, Jeppesen, H. S. & Rades, Thomas, 2023, In: Chemical Science. 14, 41, p. 11447-11455 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Wet granulation of co-amorphous indomethacin systems

    Schütz, D., Timmerhaus, A. & Grohganz, Holger, 2023, In: International Journal of Pharmaceutics. 644, 9 p., 123318.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. 2022
  46. Published

    (Co-)amorphization of enantiomers – Investigation of the amorphization process, the physical stability and the dissolution behavior

    Holzapfel, K., Liu, J., Rades, Thomas & Leopold, C. S., 2022, In: International Journal of Pharmaceutics. 616, 9 p., 121552.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    A new method to determine drug-polymer solubility through enthalpy of melting and mixing

    Meiland, Peter, Larsen, B. S., Knopp, Matthias Manne, Tho, I. & Rades, Thomas, 2022, In: International Journal of Pharmaceutics. 629, 9 p., 122391.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Additive manufacturing in respiratory sciences – Current applications and future prospects

    Bock, S., Rades, Thomas, Rantanen, Jukka & Scherließ, R., 2022, In: Advanced Drug Delivery Reviews. 186, 14 p., 114341.

    Research output: Contribution to journalReviewResearchpeer-review

  49. Published

    Combining lipid based drug delivery and amorphous solid dispersions for improved oral drug absorption of a poorly water-soluble drug

    Nora, G., Venkatasubramanian, R., Strindberg, S., Siqueira-Jørgensen, S. D., Pagano, L., Romanski, F. S., Swarnakar, N. K., Rades, Thomas & Mullertz, Anette , 2022, In: Journal of Controlled Release. 349, p. 206-212

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Development of a Microgram Scale Video-Microscopic Method to Investigate Dissolution Behavior of Poorly Water-Soluble Drugs

    Senniksen, M. B., Christfort, J. F., Marabini, R., Spillum, E., Matthews, W., Da Vià, L., Plum, J., Rades, Thomas & Mullertz, Anette , 2022, In: AAPS PharmSciTech. 23, 6, 173.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Development of a multiparticulate drug delivery system for in situ amorphisation

    Holm, T. P., Kokott, M., Knopp, Matthias Manne, Boyd, Ben, Berthelsen, R., Quodbach, J. & Löbmann, Korbinian, 2022, In: European Journal of Pharmaceutics and Biopharmaceutics. 180, p. 170-180

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Effects of polymer addition on the non-strongly interacting binary co-amorphous system carvedilol-tryptophan

    Wang, Y., Grohganz, Holger & Rades, Thomas, 2022, In: International Journal of Pharmaceutics. 617, 9 p., 121625.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Elucidating Pathway and Anesthetic Mechanism of Action of Clove Oil Nanoformulations in Fish

    Kheawfu, K., Pikulkaew, S., Wellendorph, Petrine, Jørgensen, Louise von Gersdorff, Rades, Thomas, Mullertz, Anette & Okonogi, S., 2022, In: Pharmaceutics. 14, 5, 13 p., 919.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Elucidating the Dehydration Mechanism of Nitrofurantoin Monohydrate II Using Low-Frequency Raman Spectroscopy

    Remoto, P. J. G., Bērziņš, Kārlis, Fraser-Miller, S. J., Korter, T. M., Rades, Thomas, Rantanen, Jukka & Gordon, K. C., 2022, In: Crystal Growth and Design. 22, 4, p. 2733-2741

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    Hyperthermia-Induced In Situ Drug Amorphization by Superparamagnetic Nanoparticles in Oral Dosage Forms

    Ansari, S. R., Hempel, N. J., Asad, S., Svedlindh, P., Bergström, C. A. S., Löbmann, Korbinian & Teleki, A., 2022, In: ACS Applied Materials and Interfaces. 14, 19, p. 21978–21988

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    Impact of Molecular Surface Diffusion on the Physical Stability of Co-Amorphous Systems

    Liu, J., Hwu, E., Bannow, J., Grohganz, Holger & Rades, Thomas, 2022, In: Molecular Pharmaceutics. 19, 4, p. 1183-1190

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Impact of oral gavage technique of drug-containing microcontainers on the gastrointestinal transit and absorption in rats

    Kristensen, M. N., Rades, Thomas, Boisen, A. & Mullertz, Anette , 2022, In: International Journal of Pharmaceutics. 618, 121630.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    In Situ Transformation of Electrospun Nanofibers into Nanofiber-Reinforced Hydrogels

    Martin, A., Nyman, J. N., Reinholdt, R., Cai, J., Gürtler, Anna-Lena, van der Plas, Mariena J.A., Malmsten, Martin, Rades, Thomas & Heinz, Andrea, 2022, In: Nanomaterials. 12, 14, 2437.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    Influence of Water on Amorphous Lidocaine

    Xu, X., Grohganz, Holger & Rades, Thomas, 2022, In: Molecular Pharmaceutics. 19, 9, p. 3199–3205

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    Low-Frequency Raman Spectroscopy as an Avenue to Determine the Transition Temperature of β- and γ-Relaxation in Pharmaceutical Glasses

    Bērziņš, Kārlis, Fraser-Miller, S. J., Rades, Thomas & Gordon, K. C., 2022, In: Analytical Chemistry. 94, 23, p. 8241-8248

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Published

    Pharmaceutical Technology in Europe

    Siepmann, J., Basit, A. & Rades, Thomas, 2022, In: International Journal of Pharmaceutics. 613, 1 p., 121441.

    Research output: Contribution to journalEditorialResearch

  62. Published

    Physico-chemical characterization of aspirated and simulated human gastric fluids to study their influence on the intrinsic dissolution rate of cinnarizine

    Pedersen, P. B., Berthelsen, R., Rades, Thomas, Jørgensen, S. A., Vilmann, Peter, Bar-Shalom, Daniel, Baldursdottir, S. & Mullertz, Anette , 2022, In: International Journal of Pharmaceutics. 622, 7 p., 121856.

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    Simultaneous quantification of multiple RNA cargoes co-loaded into nanoparticle-based delivery systems

    Lokras, Abhijeet, Chakravarty, A., Rades, Thomas, Christensen, D., Franzyk, Henrik, Thakur, A. & Foged, Camilla, 2022, In: International Journal of Pharmaceutics. 626, 13 p., 122171.

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. Published

    Solventless amorphization and pelletization using a high shear granulator. Part I; feasibility study using indomethacin

    Kondo, K. & Rades, Thomas, 2022, In: European Journal of Pharmaceutics and Biopharmaceutics. 181, p. 147-158

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. Published

    Solventless amorphization and pelletization using a high shear granulator. Part II; Preparation of co-amorphous mixture-layered pellets using indomethacin and arginine

    Kondo, K. & Rades, Thomas, 2022, In: European Journal of Pharmaceutics and Biopharmaceutics. 181, p. 183-194

    Research output: Contribution to journalJournal articleResearchpeer-review

  66. Published

    Stabilizing Mechanisms of β-Lactoglobulin in Amorphous Solid Dispersions of Indomethacin

    Kabedev, A., Zhuo, Xuezhi, Leng, D., Foderà, Vito, Zhao, M., Larsson, P., Bergström, C. A. S. & Löbmann, Korbinian, 2022, In: Molecular Pharmaceutics. 19, 11, p. 3922–3933

    Research output: Contribution to journalJournal articleResearchpeer-review

  67. Published

    Supersaturated amorphous solid dispersions of celecoxib prepared in situ by microwave irradiation

    Holm, T. P., Knopp, Matthias Manne, Berthelsen, R. & Löbmann, Korbinian, 2022, In: International Journal of Pharmaceutics. 626, 8 p., 122115.

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. Published

    The Binding of Alpinia galanga Oil and Its Nanoemulsion to Mammal GABA(A) Receptors Using Rat Cortical Membranes and an In Silico Modeling Platform

    Khumpirapang, N., Suknuntha, K., Wongrattanakamon, P., Jiranusornkul, S., Anuchapreeda, S., Wellendorph, Petrine, Mullertz, Anette , Rades, Thomas & Okonogi, S., 2022, In: Pharmaceutics. 14, 3, 15 p., 650.

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. Published

    Topical niclosamide (ATx201) reduces Staphylococcus aureus colonization and increases Shannon diversity of the skin microbiome in atopic dermatitis patients in a randomized, double-blind, placebo-controlled Phase 2 trial

    Weiss, A., Delavenne, E., Matias, C., Lagler, H., Simon, D., Li, P., Hansen, J. U., Dos Santos, T. P., Jana, B., Priemel, P., Bangert, C., Bauer, M., Eberl, S., Nussbaumer-Pröll, A., Anne Österreicher, Z., Matzneller, P., Quint, T., Weber, M., Nielsen, H. M., Rades, T. & 17 others, Johansen, Helle Krogh, Westh, Henrik T., Kim, W., Mylonakis, E., Friis, C., Guardabassi, Luca, Pace, J., Lundberg, C. V., M'Zali, F., Butty, P., Sørensen, N., Nielsen, H. B., Toft-Kehler, R., Guttman-Yassky, E., Stingl, G., Zeitlinger, M. & Sommer, M., 2022, In: Clinical and Translational Medicine. 12, 5, e790.

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. Published

    Zein-polycaprolactone core-shell nanofibers for wound healing

    Martin, A., Cai, J., Gürtler, Anna-Lena, van der Plas, Mariena J.A., Malmsten, Martin, Rades, Thomas & Heinz, Andrea, 2022, In: International Journal of Pharmaceutics. 621, 10 p., 121809.

    Research output: Contribution to journalJournal articleResearchpeer-review

  71. 2021
  72. Published

    The effect of the molecular weight of polyvinylpyrrolidone and the model drug on laser-induced in situ amorphization

    Hempel, N. J., Merkl, P., Knopp, Matthias Manne, Berthelsen, R., Teleki, A., Hansen, A. K., Sotiriou, G. A. & Löbmann, Korbinian, Jul 2021, In: Molecules. 26, 13, 13 p., 4035.

    Research output: Contribution to journalJournal articleResearchpeer-review

  73. Published

    A Multivariate Approach for the Determination of the Optimal Mixing Ratio of the Non-Strong Interacting Co-Amorphous System Carvedilol-Tryptophan

    Di, Rong, Liu, J., Grohganz, Holger & Rades, Thomas, 2021, In: Molecules. 26, 4, 8 p., 801.

    Research output: Contribution to journalJournal articleResearchpeer-review

  74. Published
  75. Published

    Combined Effect of the Preparation Method and Compression on the Physical Stability and Dissolution Behavior of Melt-Quenched Amorphous Celecoxib

    Bērziņš, Kārlis, Fraser-Miller, S. J., Di, Rong, Liu, J., Peltonen, L., Strachan, C. J., Rades, Thomas & Gordon, K. C., 2021, In: Molecular Pharmaceutics. 18, 3, p. 1408-1418

    Research output: Contribution to journalJournal articleResearchpeer-review

  76. Published

    Comparison of co-former performance in co-amorphous formulations: Single amino acids, amino acid physical mixtures, amino acid salts and dipeptides as co-formers

    Wu, W., Grohganz, Holger, Rades, Thomas & Löbmann, Korbinian, 2021, In: European Journal of Pharmaceutical Sciences. 156, 8 p., 105582.

    Research output: Contribution to journalJournal articleResearchpeer-review

  77. Published

    Deliquescence Behavior of Deep Eutectic Solvents

    Palmelund, H., Rantanen, Jukka & Löbmann, Korbinian, 2021, In: Applied Sciences. 11, 9 p., 1601.

    Research output: Contribution to journalLetterResearchpeer-review

  78. Published

    Design and optimization of self-nanoemulsifying drug delivery systems of clove oil for efficacy enhancement in fish anesthesia

    Kheawfu, Pikulkaew, Rades, Thomas, Mullertz, Anette , Jørgensen, Louise von Gersdorff & Okonogi, 2021, In: Journal of Drug Delivery Science and Technology. 61, 9 p., 102241.

    Research output: Contribution to journalJournal articleResearchpeer-review

  79. Published

    Design of a self-unfolding delivery concept for oral administration of macromolecules

    Jørgensen, J. R., Thamdrup, L. H. E., Kamguyan, K., Nielsen, L. H., Nielsen, Hanne Mørck, Boisen, A., Rades, Thomas & Mullertz, Anette , 2021, In: Journal of Controlled Release. 329, p. 948-954

    Research output: Contribution to journalJournal articleResearchpeer-review

  80. Published

    Development of Self-Nanoemulsifying Drug Delivery Systems Containing 4-Allylpyrocatechol for Treatment of Oral Infections Caused by Candida albicans

    Okonogi, S., Phumat, P., Khongkhunthian, S., Chaijareenont, P., Rades, Thomas & Mullertz, Anette , 2021, In: Pharmaceutics. 13, 2, 16 p., 167.

    Research output: Contribution to journalJournal articleResearchpeer-review

  81. Published

    Enabling formulations of aprepitant: in vitro and in vivo comparison of nanocrystalline, amorphous and deep eutectic solvent based formulations

    Palmelund, H., Eriksen, J. B., Bauer-Brandl, A., Rantanen, Jukka & Löbmann, Korbinian, 2021, In: International Journal of Pharmaceutics: X. 3, 100083.

    Research output: Contribution to journalJournal articleResearchpeer-review

  82. Published

    Exploring the Impact of Intestinal Fluid Components on the Solubility and Supersaturation of Danazol

    Madsen, C. M., Plum, J., Hens, B., Augustijns, P., Mullertz, Anette & Rades, Thomas, 2021, In: Journal of Pharmaceutical Sciences. 110, 6, p. 2479-2488 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  83. Published

    Formulation optimization, anesthetic activity, skin permeation, and transportation pathway of Alpinia galanga oil SNEDDS in zebrafish (Danio rerio)

    Khumpirapang, N., Jørgensen, Louise von Gersdorff, Mullertz, Anette , Rades, Thomas & Okonogi, S., 2021, In: European Journal of Pharmaceutics and Biopharmaceutics. 165, p. 193-202 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  84. Published

    Interactions of Cell-Penetrating Peptide-Modified Nanoparticles with Cells Evaluated Using Single Particle Tracking

    Streck, S., Bohr, S. S., Birch, D., Rades, Thomas, Hatzakis, Nikos, McDowell, A. & Nielsen, Hanne Mørck, 2021, In: ACS Applied Bio Materials. 4, 4, p. 3155-3165 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  85. Published

    Investigating to Optimal Ratio between Drug and Co-Former in Co-Amorphous Systems

    Rades, Thomas, 2021, In: Proceedings. 78, 1, 1 p., 27.

    Research output: Contribution to journalJournal articleResearchpeer-review

  86. Published

    Investigation into the role of the polymer in enhancing microwave-induced in situ amorphization

    Qiang, W., Löbmann, Korbinian, Knopp, Matthias Manne, McCoy, C. P., Andrews, G. P. & Zhao, M., 2021, In: International Journal of Pharmaceutics. 609, 8 p., 121157.

    Research output: Contribution to journalJournal articleResearchpeer-review

  87. Published

    Investigation on Formulation Strategies to Mitigate Compression-Induced Destabilization in Supersaturated Celecoxib Amorphous Solid Dispersions

    Bērziņš, Kārlis, Fraser-Miller, S. J., Walker, G. F., Rades, Thomas & Gordon, K. C., 2021, In: Molecular Pharmaceutics. 18, 10, p. 3882–3893

    Research output: Contribution to journalJournal articleResearchpeer-review

  88. Published

    Mechanochemical N-Chlorination Reaction of Hydantoin: In Situ Real-Time Kinetic Study by Powder X-ray Diffraction and Raman Spectroscopy

    Batista Martins, Inês Catarina, Carta, M., Haferkamp, S., Feiler, T., Delogu, F., Colacino, E. & Emmerling, F., 2021, In: ACS Sustainable Chemistry & Engineering. 9, 37, p. 12591-12601

    Research output: Contribution to journalJournal articleResearchpeer-review

  89. Published

    Microwave induced in situ amorphisation facilitated by crystalline hydrates

    Holm, T. P., Knopp, M. M., Löbmann, Korbinian & Berthelsen, R., 2021, In: European Journal of Pharmaceutical Sciences. 163, 9 p., 105858.

    Research output: Contribution to journalJournal articleResearchpeer-review

  90. Published

    Microwave-Induced in Situ Drug Amorphization Using a Mixture of Polyethylene Glycol and Polyvinylpyrrolidone

    Hempel, N. J., Knopp, Matthias Manne, Zeitler, J. A., Berthelsen, R. & Löbmann, Korbinian, 2021, In: Journal of Pharmaceutical Sciences. 110, 9, p. 3221-3229

    Research output: Contribution to journalJournal articleResearchpeer-review

  91. Published

    Monitoring the Isothermal Dehydration of Crystalline Hydrates Using Low-Frequency Raman Spectroscopy

    Robert, C., Fraser-Miller, S. J., Bērziņš, Kārlis, Okeyo, P. O., Rantanen, Jukka, Rades, Thomas & Gordon, K. C., 2021, In: Molecular Pharmaceutics. 18, 3, p. 1264-1276

    Research output: Contribution to journalJournal articleResearchpeer-review

  92. Published

    Predictive identification of co-formers in co-amorphous systems

    Chambers, L. I., Grohganz, Holger, Palmelund, H., Löbmann, Korbinian, Rades, Thomas, Musa, O. M. & Steed, J. W., 2021, In: European Journal of Pharmaceutical Sciences. 157, 9 p., 105636.

    Research output: Contribution to journalJournal articleResearchpeer-review

  93. Published

    Probabilistic modeling of an injectable aqueous crystalline suspension using influence networks

    Sekulovic, A., Petit, M., Verrijk, R., Rades, Thomas & Rantanen, Jukka, 2021, In: International Journal of Pharmaceutics. 596, 11 p., 120283.

    Research output: Contribution to journalJournal articleResearchpeer-review

  94. Published

    Screening of novel excipients for freeze-dried protein formulations

    Holm, T. P., Meng-Lund, H., Rantanen, Jukka, Jørgensen, Lene & Grohganz, Holger, 2021, In: European Journal of Pharmaceutics and Biopharmaceutics. 160, p. 55-64 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  95. Published

    Simultaneous automated image analysis and Raman spectroscopy of powders at an individual particle level

    Sekulovic, A., Verrijk, R., Rades, Thomas, Grabarek, A., Jiskoot, W., Hawe, A. & Rantanen, Jukka, 2021, In: Journal of Pharmaceutical and Biomedical Analysis. 193, 8 p., 113744.

    Research output: Contribution to journalJournal articleResearchpeer-review

  96. Published

    Studying the impact of the temperature and sorbed water during microwave-induced In Situ amorphization: A case study of celecoxib and polyvinylpyrrolidone

    Hempel, N. J., Knopp, Matthias Manne, Löbmann, Korbinian & Berthelsen, R., 2021, In: Pharmaceutics. 13, 6, 13 p., 886.

    Research output: Contribution to journalJournal articleResearchpeer-review

  97. Published

    The Influence of Drug-Polymer Solubility on Laser-Induced In Situ Drug Amorphization Using Photothermal Plasmonic Nanoparticles

    Hempel, N., Merkl, P., Knopp, Matthias Manne, Berthelsen, R., Teleki, A., Sotiriou, G. A. & Löbmann, Korbinian, 2021, In: Pharmaceutics. 13, 6, 12 p., 917.

    Research output: Contribution to journalJournal articleResearchpeer-review

  98. Published

    The Influence of Temperature and Viscosity of Polyethylene Glycol on the Rate of Microwave-Induced In Situ Amorphization of Celecoxib

    Hempel, N., Dao, T., Knopp, Matthias Manne, Berthelsen, R. & Löbmann, Korbinian, 2021, In: Molecules. 26, 1, 8 p., 110.

    Research output: Contribution to journalJournal articleResearchpeer-review

  99. Published

    The Use of Glycerol as an Enabling Excipient for Microwave-Induced In Situ Drug Amorphization

    Hempel, N., Morsch, F., Knopp, Matthias Manne, Berthelsen, R. & Löbmann, Korbinian, 2021, In: Journal of Pharmaceutical Sciences. 110, 1, p. 155-163 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  100. Published

    The influence of moisture on the storage stability of co-amorphous systems

    Liu, J., Rades, Thomas & Grohganz, Holger, 2021, In: International Journal of Pharmaceutics. 605, 120802.

    Research output: Contribution to journalJournal articleResearchpeer-review

  101. Published

    Utilizing Laser Activation of Photothermal Plasmonic Nanoparticles to Induce On-Demand Drug Amorphization inside a Tablet

    Hempel, N. J., Merkl, P., Asad, S., Knopp, M. M., Berthelsen, R., Bergström, C. A. S., Teleki, A., Sotiriou, G. A. & Löbmann, Korbinian, 2021, In: Molecular Pharmaceutics. 18, 6, p. 2254–2262

    Research output: Contribution to journalJournal articleResearchpeer-review

  102. Published

    Vancomycin-Loaded Microneedle Arrays against Methicillin-Resistant Staphylococcus Aureus Skin Infections

    Ziesmer, J., Tajpara, P., Hempel, N., Ehrstrom, M., Melican, K., Eidsmo, Liv & Sotiriou, G. A., 2021, In: Advanced Materials Technologies. 10 p., 2001307.

    Research output: Contribution to journalJournal articleResearchpeer-review

  103. Published

    X-ray Imaging for Gastrointestinal Tracking of Microscale Oral Drug Delivery Devices

    Kjeldsen, R. B., Kristensen, M. N., Gundlach, C., Thamdrup, L. H. E., Mullertz, Anette , Rades, Thomas, Nielsen, L. H., Zór, K. & Boisen, A., 2021, In: ACS Biomaterials Science and Engineering. 7, 6, p. 2538–2547

    Research output: Contribution to journalJournal articleResearchpeer-review

  104. 2020
  105. Published

    Effect of supersaturation on absorption of indomethacin and tadalafil in a single pass intestinal perfusion rat model, in the absence and presence of a precipitation inhibitor

    Strindberg, S., Plum, J., Stie, Mai Bay, Christiansen, M. L., Nielsen, L. H., Rades, Thomas & Mullertz, Anette , Jun 2020, In: European Journal of Pharmaceutics and Biopharmaceutics. 151, p. 108-115

    Research output: Contribution to journalJournal articleResearchpeer-review

  106. Published

    The influence of drug and polymer particle size on the in situ amorphization using microwave irradiation

    Hempel, N. J., Knopp, Matthias Manne, Berthelsen, R., Zeitler, J. A. & Löbmann, Korbinian, Apr 2020, In: European Journal of Pharmaceutics and Biopharmaceutics. 149, p. 77-84 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  107. Published

    Poorly soluble drugs

    Siepmann, J., Rades, Thomas, Mullertz, Anette & Loftsson, T., 15 Mar 2020, In: International Journal of Pharmaceutics. 577, 119055.

    Research output: Contribution to journalEditorialResearch

  108. Published

    In Vitro, Ex Vivo and In Vivo Evaluation of Microcontainers for Oral Delivery of Insulin

    Jørgensen, J. R., Yu, F., Ramakrishnan, V., Nielsen, L. H., Nielsen, Hanne Mørck, Boisen, A., Rades, Thomas & Mullertz, Anette , 7 Jan 2020, In: Pharmaceutics. 12, 1, 14 p., 48.

    Research output: Contribution to journalJournal articleResearchpeer-review

  109. Published

    Comparison of induction methods for supersaturation: pH shift versus solvent shift

    Plum, J., Bavnhoj, C., Palmelund, H., Perez-Alos, L., Mullertz, Anette & Rades, Thomas, 5 Jan 2020, In: International Journal of Pharmaceutics. 573, 8 p., 118862.

    Research output: Contribution to journalJournal articleResearchpeer-review

  110. Published

    Amino acids as stabilizers for spray-dried simvastatin powder for inhalation

    Lu, W., Rades, Thomas, Rantanen, Jukka, Chan, H. & Yang, Mingshi, 2020, In: International Journal of Pharmaceutics. 572, 12 p., 118724.

    Research output: Contribution to journalJournal articleResearchpeer-review

  111. Published

    Amorphous drug stabilization using mesoporous materials

    Veloso, D. F. M. C., Knopp, Matthias Manne & Löbmann, Korbinian, 2020, Drug delivery trends. Elsevier, Vol. 3. p. 151-166

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  112. Published

    Comparison of induction methods for supersaturation: Amorphous dissolution versus solvent shift

    Plum, J., Bavnhoj, C. G., Eliasen, Jannik Nicklas, Rades, Thomas & Mullertz, Anette , 2020, In: European Journal of Pharmaceutics and Biopharmaceutics. 152, p. 35-43 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  113. Published

    Constraints on CaCO3 precipitation in superabsorbent polymer by aerobic bacteria

    Nielsen, S. D., Koren, K., Löbmann, Korbinian, Hinge, M., Scoma, A., Kjeldsen, K. U. & Roy, H., 2020, In: Applied Microbiology and Biotechnology. 104, 1, p. 365-375

    Research output: Contribution to journalJournal articleResearchpeer-review

  114. Published

    Convection-Induced vs. Microwave Radiation-Induced in situ Drug Amorphization

    Hempel, N., Knopp, Matthias Manne, Berthelsen, R. & Löbmann, Korbinian, 2020, In: Molecules. 25, 5, 7 p., 1068.

    Research output: Contribution to journalJournal articleResearchpeer-review

  115. Published

    Data-enriched edible pharmaceuticals (DEEP) of medical cannabis by inkjet printing

    Öblom, H., Cornett, Claus, Bøtker, Johan Peter, Frøkjær, Sven, Hansen, Harald S., Rades, Thomas, Rantanen, Jukka & Genina, Natalja, 2020, In: International Journal of Pharmaceutics. 589, p. 1-11 119866.

    Research output: Contribution to journalJournal articleResearchpeer-review

  116. Published

    Determination of the Optimal Molar Ratio in Amino Acid-Based Coamorphous Systems

    Liu, J., Rades, Thomas & Grohganz, Holger, 2020, In: Molecular Pharmaceutics. 17, 4, p. 1335-1342 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  117. Published

    Direct Measurement of Lateral Molecular Diffusivity on the Surface of Supersaturated Amorphous Solid Dispersions by Atomic Force Microscopy

    Bannow, J., Karl, M., Larsen, P. E., Hwu, E. T. & Rades, Thomas, 2020, In: Molecular Pharmaceutics. 17, 5, p. 1715-1722 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  118. Published

    Enhancing Stability and Tooth Bleaching Activity of Carbamide Peroxide by Electrospun Nanofibrous Film

    Okonogi, S., Kaewpinta, A., Rades, Thomas, Mullertz, Anette , Yang, Mingshi, Khongkhunthian, S. & Chaijareenont, P., 2020, In: Pharmaceuticals. 13, 11, 20 p., 381.

    Research output: Contribution to journalJournal articleResearchpeer-review

  119. Published

    Exposure of liposomes containing nanocrystallised ciprofloxacin to digestive media induces solid-state transformation and altered in vitro drug release

    Li, T., Hawley, A., Rades, Thomas & Boyd, B. J., 2020, In: Journal of Controlled Release. 323, p. 350-360 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  120. Published

    Formulation of co-amorphous systems from naproxen and naproxen sodium and in situ monitoring of physicochemical state changes during dissolution testing by Raman spectroscopy

    Ueda, H., Bøtker, Johan Peter, Edinger, M., Löbmann, Korbinian, Grohganz, Holger, Mullertz, Anette , Rades, Thomas & Østergaard, Jesper, 2020, In: International Journal of Pharmaceutics. 587, 119662.

    Research output: Contribution to journalJournal articleResearchpeer-review

  121. Published

    Functionalised calcium carbonate as a coformer to stabilize amorphous drugs by mechanochemical activation

    Liu, J., Rades, Thomas, Tho, I. & Kissi, E. O., 2020, In: European Journal of Pharmaceutics and Biopharmaceutics. 155, p. 22-28 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  122. Published

    Highly Elastic and Water Stable Zein Microfibers as a Potential Drug Delivery System for Wound Healing

    Akhmetova, A., Lanno, G., Kogermann, K., Malmsten, Martin, Rades, Thomas & Heinz, Andrea, 2020, In: Pharmaceutics. 12, 5, 19 p., 458.

    Research output: Contribution to journalJournal articleResearchpeer-review

  123. Published

    Hot Melt Coating of Amorphous Carvedilol

    Bannow, J., Koren, L., Salar-Behzadi, S., Löbmann, Korbinian, Zimmer, A. & Rades, Thomas, 2020, In: Pharmaceutics. 12, 6, 13 p., 519.

    Research output: Contribution to journalJournal articleResearchpeer-review

  124. Published

    Improving the drug load and in vitro performance of supersaturated self-nanoemulsifying drug delivery systems (super-SNEDDS) using polymeric precipitation inhibitors

    Bannow, J., Yorulmaz, Y., Löbmann, Korbinian, Mullertz, Anette & Rades, Thomas, 2020, In: International Journal of Pharmaceutics. 575, 1188960.

    Research output: Contribution to journalJournal articleResearchpeer-review

  125. Published

    Influence of polymer addition on the amorphization, dissolution and physical stability of co-amorphous systems

    Liu, J., Grohganz, Holger & Rades, Thomas, 2020, In: International Journal of Pharmaceutics. 588, p. 1-9 9 p., 119768.

    Research output: Contribution to journalJournal articleResearchpeer-review

  126. Published

    Influence of the Polymer Glass Transition Temperature and Molecular Weight on Drug Amorphization Kinetics Using Ball Milling

    Asgreen, Camilla Jantzen, Knopp, Matthias Manne, Skytte, J. & Löbmann, Korbinian, 2020, In: Pharmaceutics. 12, 6, 6 p., 483.

    Research output: Contribution to journalJournal articleResearchpeer-review

  127. Published

    Influence of water of crystallization on the ternary phase behavior of a drug and deep eutectic solvent

    Palmelund, H., Boyd, B. J., Rantanen, Jukka & Löbmann, Korbinian, 2020, In: Journal of Molecular Liquids. 315, p. 1-7 113727.

    Research output: Contribution to journalJournal articleResearchpeer-review

  128. Published

    Microwave-Induced In Situ Amorphization: A New Strategy for Tackling the Stability Issue of Amorphous Solid Dispersions

    Qiang, W., Löbmann, Korbinian, McCoy, C. P., Andrews, G. P. & Zhao, M., 2020, In: Pharmaceutics. 12, 7, 19 p., 655.

    Research output: Contribution to journalReviewResearchpeer-review

  129. Published

    Preparation of Co-Amorphous Systems by Freeze-Drying

    Wostry, M., Plappert, H. & Grohganz, Holger, 2020, In: Pharmaceutics. 12, 10, 12 p., 941.

    Research output: Contribution to journalJournal articleResearchpeer-review

  130. Published

    Simultaneous investigation of the liquid transport and swelling performance during tablet disintegration

    Al-Sharabi, M., Markl, D., Mudley, T., Bawuah, P., Karttunen, A., Ridgway, C., Gane, P., Ketolainen, J., Peiponen, K., Rades, Thomas & Zeitler, J. A., 2020, In: International Journal of Pharmaceutics. 584, 11 p., 119380.

    Research output: Contribution to journalJournal articleResearchpeer-review

  131. Published

    Single particles as resonators for thermomechanical analysis

    Okeyo, P. O., Larsen, P. E., Kissi, E. O., Ajalloueian, F., Rades, Thomas, Rantanen, Jukka & Boisen, A., 2020, In: Nature Communications. 11, 1, 11 p., 1235.

    Research output: Contribution to journalJournal articleResearchpeer-review

  132. Published

    Solving the Computational Puzzle: Toward a Pragmatic Pathway for Modeling Low-Energy Vibrational Modes of Pharmaceutical Crystals

    Bērziņš, Kārlis, Sutton, J. J., Fraser-Miller, S. J., Rades, Thomas, Korter, T. M. & Gordon, K. C., 2020, In: Crystal Growth & Design. 20, 10, p. 6947-6955

    Research output: Contribution to journalJournal articleResearchpeer-review

  133. Published

    Temperature-Modulated Micromechanical Thermal Analysis with Microstring Resonators Detects Multiple Coherent Features of Small Molecule Glass Transition

    Karl, M., Thamdrup, L. H. E., Rantanen, Jukka, Boisen, A. & Rades, Thomas, 2020, In: Sensors. 20, 4, 14 p., 1019.

    Research output: Contribution to journalJournal articleResearchpeer-review

  134. Published

    Using in vitro lipolysis and SPECT/CT in vivo imaging to understand oral absorption of fenofibrate from lipid-based drug delivery systems

    Tran, T., Bonlokke, P., Rodriguez-Rodriguez, C., Nosrati, Z., Esquinas, P. L., Borkar, N., Plum, J., Strindberg, S., Karagiozov, S., Rades, Thomas, Mullertz, Anette , Saatchi, K. & Hafeli, U. O., 2020, In: Journal of Controlled Release. 317, p. 375-384

    Research output: Contribution to journalJournal articleResearchpeer-review

  135. 2019
  136. Published

    Determining Thermal Conductivity of Small Molecule Amorphous Drugs with Modulated Differential Scanning Calorimetry and Vacuum Molding Sample Preparation

    Karl, M., Rantanen, Jukka & Rades, Thomas, 6 Dec 2019, In: Pharmaceutics. 11, 12, 7 p., 670.

    Research output: Contribution to journalJournal articleCommunication

  137. Published

    The role interplay between mesoporous silica pore volume and surface area and their effect on drug loading capacity

    Bavnhøj, C. G., Knopp, Matthias Manne, Madsen, C. & Löbmann, Korbinian, 1 Dec 2019, In: International Journal of Pharmaceutics: X. 1, 5 p., 100008.

    Research output: Contribution to journalJournal articleResearchpeer-review

  138. Published

    Comparison of bulk and microfluidics methods for the formulation of poly-lactic-co-glycolic acid (PLGA) nanoparticles modified with cell-penetrating peptides of different architectures

    Streck, S., Neumann, H., Nielsen, Hanne Mørck, Rades, Thomas & McDowell, A., Dec 2019, In: International Journal of Pharmaceutics: X. 1, 9 p., 100030.

    Research output: Contribution to journalJournal articleResearchpeer-review

  139. Published

    Spray-drying of inhalable, multifunctional formulations for the treatment of biofilms formed in cystic fibrosis

    Lababidi, N., Kissi, E. O., Elgaher, W. A. M., Sigal, V., Haupenthal, J., Schwarz, B. C., Hirsch, A. K. H., Rades, Thomas & Schneider, M., 28 Nov 2019, In: Journal of Controlled Release. 314, p. 62-71

    Research output: Contribution to journalJournal articleResearchpeer-review

  140. Published

    The distribution of cell-penetrating peptides on polymeric nanoparticles prepared using microfluidics and elucidated with small angle X-ray scattering

    Streck, S., Clulow, A. J., Nielsen, Hanne Mørck, Rades, Thomas, Boyd, B. J. & McDowell, A., 1 Nov 2019, In: Journal of Colloid and Interface Science. 555, p. 438-448 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  141. Published

    Utilizing nanoparticles for improving anti-biofilm effects of azithromycin: A head-to-head comparison of modified hyaluronic acid nanogels and coated poly (lactic-co-glycolic acid) nanoparticles

    Kłodzińska, S. N., Wan, F., Jumaa, H., Sternberg, C., Rades, Thomas & Nielsen, Hanne Mørck, 1 Nov 2019, In: Journal of Colloid and Interface Science. 555, p. 595-606 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  142. Published

    Inhalable co-amorphous budesonide-arginine dry powders prepared by spray drying

    Lu, W., Rades, Thomas, Rantanen, Jukka & Yang, Mingshi, 30 Jun 2019, In: International Journal of Pharmaceutics. 565, p. 1-8 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  143. Published

    In vitro digestion models to evaluate lipid based drug delivery systems; present status and current trends

    Berthelsen, R., Klitgaard, Mette, Rades, Thomas & Mullertz, Anette , 29 Jun 2019, In: Advanced Drug Delivery Reviews. 142, p. 35-49 15 p.

    Research output: Contribution to journalReviewResearchpeer-review

  144. Published

    Direct Measurement of Amorphous Solubility

    Stukelj, J., Svanback, S., Agopov, M., Löbmann, Korbinian, Strachan, C. J., Rades, Thomas & Yliruusi, J., 4 Jun 2019, In: Analytical Chemistry. 91, 11, p. 7411-7417

    Research output: Contribution to journalJournal articleResearchpeer-review

  145. Published

    Biorelevant intrinsic dissolution profiling in early drug development: Fundamental, methodological, and industrial aspects

    Bergstrom, C. A. S., Box, K., Holm, R., Matthews, W., McAllister, M., Mullertz, Anette , Rades, Thomas, Schaefer, K. J. & Teleki, A., Jun 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 139, p. 101-114

    Research output: Contribution to journalReviewResearchpeer-review

  146. Published

    Imaging of dehydration in particulate matter using Raman line-focus microscopy

    Okeyo, P. O., Ilchenko, O., Slipets, R., Larsen, P. E., Boisen, A., Rades, Thomas & Rantanen, Jukka, 17 May 2019, In: Scientific Reports. 9, 11 p., 7525.

    Research output: Contribution to journalJournal articleResearchpeer-review

  147. Published

    Direct Comparison of Standard Transmission Electron Microscopy and Cryogenic-TEM in Imaging Nanocrystals Inside Liposomes

    Li, T., Nowell, C. J., Cipolla, D., Rades, Thomas & Boyd, B. J., Apr 2019, In: Molecular Pharmaceutics. 16, 4, p. 1775-1781

    Research output: Contribution to journalJournal articleResearchpeer-review

  148. Published

    In situ co-amorphisation in coated tablets – The combination of carvedilol with aspartic acid during immersion in an acidic medium

    Petry, I., Löbmann, Korbinian, Grohganz, Holger, Rades, Thomas & Leopold, C. S., 10 Mar 2019, In: International Journal of Pharmaceutics. 558, p. 357-366 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  149. Published

    Design of Inhalable Solid Dosage Forms of Budesonide and Theophylline for Pulmonary Combination Therapy

    Leng, D., Kissi, E. O., Löbmann, Korbinian, Thanki, K., Fattal, E., Rades, Thomas, Foged, Camilla & Yang, Mingshi, 7 Mar 2019, In: AAPS PharmSciTech. 20, 3, 137.

    Research output: Contribution to journalJournal articleResearchpeer-review

  150. Published

    Transformations between Co-Amorphous and Co-Crystal Systems and Their Influence on the Formation and Physical Stability of Co-Amorphous Systems

    Wu, W., Wang, Y., Löbmann, Korbinian, Grohganz, Holger & Rades, Thomas, 4 Mar 2019, In: Molecular Pharmaceutics. 16, 3, p. 1294-1304 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  151. Published

    Whey proteins as stabilizers in amorphous solid dispersions

    Mishra, J., Bohr, A., Rades, Thomas, Grohganz, Holger & Löbmann, Korbinian, 1 Feb 2019, In: European Journal of Pharmaceutical Sciences. 128, p. 144-151 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  152. Published

    Process Optimization and Upscaling of Spray-Dried Drug-Amino acid Co-Amorphous Formulations

    Kasten, G., Duarte, Í., Paisana, M., Löbmann, Korbinian, Rades, Thomas & Grohganz, Holger, 9 Jan 2019, In: Pharmaceutics. 11, 1, 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  153. Published

    Characterising glass transition temperatures and glass dynamics in mesoporous silica-based amorphous drugs

    Kissi, E. O., Ruggiero, M. T., Hempel, N. J., Song, Z., Grohganz, Holger, Rades, Thomas & Löbmann, Korbinian, 1 Jan 2019, In: Physical Chemistry Chemical Physics. 21, 35, p. 19686-19694 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  154. Published

    Dipeptides as co-formers in co-amorphous systems

    Wu, W., Löbmann, Korbinian, Schnitzkewitz, J., Knuhtsen, A., Pedersen, D. S., Rades, Thomas & Grohganz, Holger, 1 Jan 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 134, p. 68-76 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  155. Published

    Influence of Glass Forming Ability on the Physical Stability of Supersaturated Amorphous Solid Dispersions

    Blaabjerg, L. I., Bulduk, B., Lindenberg, E., Löbmann, Korbinian, Rades, Thomas & Grohganz, Holger, 1 Jan 2019, In: Journal of Pharmaceutical Sciences. 108, 8, p. 2561-2569

    Research output: Contribution to journalJournal articleResearchpeer-review

  156. Published

    Exploring the utility of the Chasing-rinciple: influence of drug-free SNEDDS composition on solubilization of carvedilol, cinnarizine and R3040 in aqueous suspension

    Jorgensen, S. D. S., Rades, Thomas, Mu, Huiling, Graeser, K. & Mullertz, Anette , Jan 2019, In: Acta Pharmaceutica Sinica B. 9, 1, p. 194-201

    Research output: Contribution to journalLetterResearchpeer-review

  157. Published

    A co-amorphous form of a substance and a protein

    Mishra, J., Bohr, A., Berg, T. H. A., Löbmann, Korbinian, Rades, Thomas, Grohganz, Holger & Water, J. J., 2019, Patent No. US201903078886A1

    Research output: Patent

  158. Published

    Co-former selection for co-amorphous drug-amino acid formulations

    Kasten, G., Löbmann, Korbinian, Grohganz, Holger & Rades, Thomas, 2019, In: International Journal of Pharmaceutics. 557, p. 366-373

    Research output: Contribution to journalJournal articleResearchpeer-review

  159. Published

    Controlling the size and shape of liposomal ciprofloxacin nanocrystals by varying the lipid bilayer composition and drug to lipid ratio

    Li, T., Clulow, A. J., Nowell, C. J., Hawley, A., Cipolla, D., Rades, Thomas & Boyd, B. J., 2019, In: Journal of Colloid and Interface Science. 555, p. 361-372 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  160. Published

    Crystalline adduct of moxifloxacin with trans-cinnamic acid to reduce the aqueous solubility and dissolution rate for improved residence time in the lungs

    Eedara, B. B., Tucker, I. G., Zujovic, Z. D., Rades, Thomas, Price, J. R. & Das, S. C., 2019, In: European Journal of Pharmaceutical Sciences. 136, 104961.

    Research output: Contribution to journalJournal articleResearchpeer-review

  161. Published

    Determination of Stable Co-Amorphous Drug-Drug Ratios from the Eutectic Behavior of Crystalline Physical Mixtures

    Kissi, E. O., Khorami, Keyoomars & Rades, Thomas, 2019, In: Pharmaceutics. 11, 11 p., 628.

    Research output: Contribution to journalJournal articleResearchpeer-review

  162. Published

    Difficulties of Subsurface Liquid Front Tracking in Porous Media with Terahertz Pulsed Imaging

    Al-Sharabi, M., Mudley, T., Markl, D., Bawuah, P., Karttunen, A. P., Ridgway, C. J., Gane, P. A. C., Ketolainen, J., Peiponen, K. E., Rades, Thomas & Zeitler, J. A., 2019, 2019 - 44th International Conference on Infrared, Millimeter, and Terahertz Waves. IEEE, 8874143. (International Conference on Infrared, Millimeter, and Terahertz Waves, IRMMW-THz, Vol. 2019-September).

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

  163. Published

    Efflux Inhibitor Bicalutamide Increases Oral Bioavailability of the Poorly Soluble Efflux Substrate Docetaxel in Co-Amorphous Anti-Cancer Combination Therapy

    Bohr, A., Nascimento, T. L., Harmankaya, N., Weisser, J. J., Wang, Y., Grohganz, Holger, Rades, Thomas & Löbmann, Korbinian, 2019, In: Molecules. 24, 2, 13 p., 266.

    Research output: Contribution to journalJournal articleResearchpeer-review

  164. Published

    Evaluation of the effects of spray drying parameters for producing cubosome powder precursors

    von Halling Laier, C., Sonne Alstrøm, T., Travers Bargholz, M., Bjerg Sjøltov, P., Rades, Thomas, Boisen, A. & Nielsen, L. H., 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 135, p. 44-48

    Research output: Contribution to journalJournal articleResearchpeer-review

  165. Published

    Exploring the chemical space for freeze-drying excipients

    Meng-Lund, H., Holm, T. P., Poso, A., Jørgensen, Lene, Rantanen, Jukka & Grohganz, Holger, 2019, In: International Journal of Pharmaceutics. 566, p. 254-263 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  166. Published

    Fenofibrate oral absorption from SNEDDS and super-SNEDDS is not significantly affected by lipase inhibition in rats

    Michaelsen, M. H., Siqueira Jørgensen, S. D., Abdi, I. M., Wasan, K. M., Rades, Thomas & Mullertz, Anette , 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 142, p. 258-264 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  167. Published

    Hyaluronic acid-based nanogels improve in vivo compatibility of the anti-biofilm peptide DJK-5

    Kłodzińska, S. N., Pletzer, D., Rahanjam, N., Rades, Thomas, Hancock, R. E. W. & Nielsen, Hanne Mørck, 2019, In: Nanomedicine: Nanotechnology, Biology, and Medicine. 20, 102022.

    Research output: Contribution to journalJournal articleResearchpeer-review

  168. Published

    Impact of drug loading in mesoporous silica-amorphous formulations on the physical stability of drugs with high recrystallization tendency

    Antonino, R. S. C. M. Q., Ruggiero, M., Song, Z., Nascimento, T. L., Lima, E. M., Bohr, A., Knopp, Matthias Manne & Löbmann, Korbinian, 2019, In: International Journal of Pharmaceutics: X. 1, 7 p., 100026.

    Research output: Contribution to journalJournal articleResearchpeer-review

  169. Published

    Low-Frequency Raman Spectroscopic Study on Compression-Induced Destabilization in Melt-Quenched Amorphous Celecoxib

    Bērziņš, Kārlis, Fraser-Miller, S. J., Rades, Thomas & Gordon, K. C., 2019, In: Molecular Pharmaceutics. 16, 8, p. 3678-3686 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  170. Published

    Mechanochemical activated dry amorphisation by milling equilibrium between ap mesoporous silica

    Hoefer, H. H., Monsuur, F. H., Pauly, T., Choudhari, Y., Löbmann, Korbinian & Rades, Thomas, 2019, Patent No. US20190350855A1

    Research output: Patent

  171. Published

    Microcontainers for oral insulin delivery - in vitro studies of permeation enhancement

    Rune Jørgensen, J., Leth Jepsen, M., Hagner Nielsen, L., Dufva, M., Nielsen, Hanne Mørck, Rades, Thomas, Boisen, A. & Mullertz, Anette , 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 143, p. 98-105

    Research output: Contribution to journalJournal articleResearchpeer-review

  172. Published

    Microcontainers for protection of oral vaccines, in vitro and in vivo evaluation

    von Halling Laier, C., Gibson, B., Moreno, J. A. S., Rades, Thomas, Hook, S., Nielsen, L. H. & Boisen, A., 2019, In: Journal of Controlled Release. 294, p. 91-101 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  173. Published

    Non-aqueous topical compositions comprising a halogenated salicylanilide

    Sommer, M., Li, P., Frandsen, C. H., Nielsen, Hanne Mørck, Priemel, P. A. & Rades, Thomas, 2019, Patent No. US20190151231A1

    Research output: Patent

  174. Published

    Optimization of Infrared Microscopy to Assess Secondary Structure of Insulin Molecules Within Individual Subvisible Particles in Aqueous Formulations

    Schack, M. M., Moller, E. H., Friderichsen, A. V., Carpenter, J. F., Rades, Thomas & Groenning, M., 2019, In: Journal of Pharmaceutical Sciences. 108, 3, p. 1117-1129

    Research output: Contribution to journalJournal articleResearchpeer-review

  175. Published

    Self-emulsifying drug delivery systems (SEDDS) – The splendid comeback of an old technology

    Bernkop-Schnürch, A., Mullertz, Anette & Rades, Thomas, 2019, In: Advanced Drug Delivery Reviews. 142, p. 1-2 2 p.

    Research output: Contribution to journalEditorialResearchpeer-review

  176. Published

    Solid State Characterization of Ciprofloxacin Liposome Nanocrystals

    Li, T., Mudie, S., Cipolla, D., Rades, Thomas & Boyd, B. J., 2019, In: Molecular Pharmaceutics. 16, 1, p. 184-194 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  177. Published

    Spectroscopic Evidence of Tertiary Structural Differences Between Insulin Molecules in Fibrils

    Schack, M. M., Dahl, K., Rades, Thomas, Groenning, M. & Carpenter, J. F., 2019, In: Journal of Pharmaceutical Sciences. 108, 9, p. 2871-2879

    Research output: Contribution to journalJournal articleResearchpeer-review

  178. Published

    Tailor-made solvents for pharmaceutical use? Experimental and computational approach for determining solubility in deep eutectic solvents (DES)

    Palmelund, H., Andersson, M. P., Asgreen, Camilla Jantzen, Boyd, B. J., Rantanen, Jukka & Löbmann, Korbinian, 2019, In: International Journal of Pharmaceutics: X. 1, 9 p., 100034.

    Research output: Contribution to journalJournal articleResearchpeer-review

  179. Published

    Using dextran of different molecular weights to achieve faster freeze-drying and improved storage stability of lactate dehydrogenase

    Larsen, B. S., Skytte, J., Svagan, A. J., Meng-Lund, H., Grohganz, Holger & Löbmann, Korbinian, 2019, In: Pharmaceutical Development and Technology. 24, 3, p. 323-328

    Research output: Contribution to journalJournal articleResearchpeer-review

  180. 2018
  181. Published

    Ultra Sensitive Micro String Resonators for Solid State Thermomechanical Analysis of Small and Large Molecules

    Karl, M., Larsen, P. E., Rangacharya, V., Hwu, E. T., Rantanen, Jukka, Boisen, A. & Rades, Thomas, 19 Dec 2018, In: Journal of the American Chemical Society. 140, 50, p. 17522-17531

    Research output: Contribution to journalJournal articleResearchpeer-review

  182. Published

    In situ co-amorphisation of arginine with indomethacin or furosemide during immersion in an acidic medium – A proof of concept study

    Petry, I., Löbmann, Korbinian, Grohganz, Holger, Rades, Thomas & Leopold, C. S., 1 Dec 2018, In: European Journal of Pharmaceutics and Biopharmaceutics. 133, p. 151-160 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  183. Published

    Influence of preparation technique on co-amorphization of carvedilol with acidic amino acids

    Mishra, J., Löbmann, Korbinian, Grohganz, Holger & Rades, Thomas, 1 Dec 2018, In: International Journal of Pharmaceutics. 552, 1-2, p. 407-413

    Research output: Contribution to journalJournal articleResearchpeer-review

  184. Published

    In vitro and in vivo comparison between crystalline and co-amorphous salts of naproxen-arginine

    Kasten, G., Lobo, L., Dengale, S., Grohganz, Holger, Rades, Thomas & Löbmann, Korbinian, 1 Nov 2018, In: European Journal of Pharmaceutics and Biopharmaceutics. 132, p. 192-199 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  185. Published

    Special issue on “Formulation strategies and manufacturing technologies to enhance non-invasive drug delivery”

    Löbmann, Korbinian, Bohr, A. & Yang, Mingshi, 1 Nov 2018, In: Asian Journal of Pharmaceutical Sciences. 13, 6, p. 505-506 2 p.

    Research output: Contribution to journalEditorialResearchpeer-review

  186. Published

    Spray dried cubosomes with ovalbumin and Quil-A as a nanoparticulate dry powder vaccine formulation

    von Halling Laier, C., Gibson, B., van de Weert, Marco, Boyd, B. J., Rades, Thomas, Boisen, A., Hook, S. & Nielsen, L. H., 25 Oct 2018, In: International Journal of Pharmaceutics. 550, 1-2, p. 35-44 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  187. Published

    Aspartame as a co-former in co-amorphous systems

    Wu, W., Löbmann, Korbinian, Schnitzkewitz, J., Knuhtsen, A., Pedersen, D. S., Grohganz, Holger & Rades, Thomas, 5 Oct 2018, In: International Journal of Pharmaceutics. 549, 1-2, p. 380-387

    Research output: Contribution to journalJournal articleResearchpeer-review

  188. Published

    Organic acids as co-formers for co-amorphous systems - Influence of variation in molar ratio on the physicochemical properties of the co-amorphous systems

    Wu, W., Ueda, H., Lobmann, K., Rades, Thomas & Grohganz, Holger, Oct 2018, In: European Journal of Pharmaceutics and Biopharmaceutics. 131, p. 25-32

    Research output: Contribution to journalJournal articleResearchpeer-review

  189. Published

    The Influence of Polymers on the Supersaturation Potential of Poor and Good Glass Formers

    Blaabjerg, L. I., Grohganz, Holger, Lindenberg, E., Löbmann, Korbinian, Mullertz, Anette & Rades, Thomas, 21 Sep 2018, In: Pharmaceutics. 10, 4, 14 p., 164.

    Research output: Contribution to journalJournal articleResearchpeer-review

  190. Published

    Immune responses induced by nano-self-assembled lipid adjuvants based on a monomycoloyl glycerol analogue after vaccination with the Chlamydia trachomatis major outer membrane protein

    Rodrigues, L., Raftopoulos, K. N., Tandrup Schmidt, S., Schneider, F., Dietz, H., Rades, Thomas, Franzyk, Henrik, Pedersen, Anders Elm, Papadakis, C. M., Christensen, D., Winter, G., Foged, Camilla & Hubert, M., 10 Sep 2018, In: Journal of controlled release : official journal of the Controlled Release Society. 285, p. 12-22 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  191. Published

    The Role of Glass Transition Temperatures in Coamorphous Drug-Amino Acid Formulations

    Kissi, E. O., Kasten, G., Löbmann, Korbinian, Rades, Thomas & Grohganz, Holger, 4 Sep 2018, In: Molecular Pharmaceutics. 15, 9, p. 4247–4256

    Research output: Contribution to journalJournal articleResearchpeer-review

  192. Published

    Addition of Cationic Surfactants to Lipid-Based Formulations of Poorly Water-Soluble Acidic Drugs Alters the Phase Distribution and the Solid-State Form of the Precipitate Upon In Vitro Lipolysis

    Khan, J., Rades, Thomas & Boyd, Ben, Sep 2018, In: Journal of Pharmaceutical Sciences. 107, 9, p. 2420-2427 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  193. Published

    Effect of amorphous phase separation and crystallization on the in vitro and in vivo performance of an amorphous solid dispersion

    Knopp, Matthias Manne, Wendelboe, J., Holm, R. & Rades, Thomas, Sep 2018, In: European Journal of Pharmaceutics and Biopharmaceutics. 130, p. 290-295

    Research output: Contribution to journalJournal articleResearchpeer-review

  194. Published

    Poly(ethylene carbonate)-containing polylactic acid microparticles with rifampicin improve drug delivery to macrophages

    Priemel, P. A., Wang, Y., Bohr, A., Water, J. J., Yang, Mingshi & Nielsen, Hanne Mørck, Aug 2018, In: Journal of Pharmacy and Pharmacology. 70, 8, p. 1009-1021

    Research output: Contribution to journalJournal articleResearchpeer-review

  195. Published

    The use of molecular descriptors in the development of co-amorphous formulations

    Meng-Lund, H. M. L., Korgaard, G. K., Jensen, K. B. T., Poso, A., Pantsar, T., Rades, Thomas, Rantanen, Jukka & Grohganz, Holger, 1 Jul 2018, In: European Journal of Pharmaceutical Sciences. 119, p. 31 38 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  196. Published

    A Platform for Preparing Homogeneous Proteinaceous Subvisible Particles With Distinct Morphologies

    Schack, M. M., Moller, E. H., Carpenter, J. F., Rades, Thomas & Groenning, M., Jul 2018, In: Journal of Pharmaceutical Sciences. 107, 7, p. 1842-1851

    Research output: Contribution to journalJournal articleResearchpeer-review

  197. Published

    Quantification of microwave-induced amorphization of celecoxib in PVP tablets using transmission Raman spectroscopy

    Edinger, M., Knopp, Matthias Manne, Kerdoncuff, H., Rantanen, Jukka, Rades, Thomas & Löbmann, Korbinian, 30 May 2018, In: European Journal of Pharmaceutical Sciences. 117, p. 62-67

    Research output: Contribution to journalJournal articleResearchpeer-review

  198. Published

    Application of a Salt Coformer in a Co-Amorphous Drug System Dramatically Enhances the Glass Transition Temperature: A Case Study of the Ternary System Carbamazepine, Citric Acid, and L-Arginine

    Ueda, H., Wu, W., Löbmann, Korbinian, Grohganz, Holger, Mullertz, Anette & Rades, Thomas, May 2018, In: Molecular Pharmaceutics. 15, 5, p. 2036-2044

    Research output: Contribution to journalJournal articleResearchpeer-review

  199. Published

    Induction of Cytotoxic T-Lymphocyte Responses Upon Subcutaneous Administration of a Subunit Vaccine Adjuvanted With an Emulsion Containing the Toll-Like Receptor 3 Ligand Poly(I:C)

    Schmidt, S. T., Pedersen, G. K., Neustrup, M. A., Korsholm, K. S., Rades, Thomas, Andersen, P., Foged, Camilla & Christensen, D., 30 Apr 2018, In: Frontiers in Immunology. 9, 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  200. Published

    A fast and reliable DSC-based method to determine the monomolecular loading capacity of drugs with good glass-forming ability in mesoporous silica

    Hempel, N., Brede, K., Olesen, N. E., Genina, Natalja, Knopp, Matthias Manne & Löbmann, Korbinian, 18 Apr 2018, In: International Journal of Pharmaceutics. 544, 1, p. 153-57

    Research output: Contribution to journalJournal articleResearchpeer-review

  201. Published

    Influence of Solvent Composition on the Performance of Spray-Dried Co-Amorphous Formulations

    Mishra, J., Rades, Thomas, Löbmann, Korbinian & Grohganz, Holger, 12 Apr 2018, In: Pharmaceutics. 10, 2, p. 1-13

    Research output: Contribution to journalJournal articleResearchpeer-review

  202. Published

    Comparison of two DSC-based methods to predict drug-polymer solubility

    Rask, M. B., Knopp, Matthias Manne, Olesen, N. E., Holm, R. & Rades, Thomas, 5 Apr 2018, In: International Journal of Pharmaceutics. 540, 1-2, p. 98-105

    Research output: Contribution to journalJournal articleResearchpeer-review

  203. Published

    Glass-Transition Temperature of the β-Relaxation as the Major Predictive Parameter for Recrystallization of Neat Amorphous Drugs

    Kissi, E. O., Grohganz, Holger, Löbmann, Korbinian, Ruggiero, M. T., Zeitler, J. A. & Rades, Thomas, 15 Mar 2018, In: Journal of Physical Chemistry Part B: Condensed Matter, Materials, Surfaces, Interfaces & Biophysical. 122, 10, p. 2803-2808 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  204. Published

    Is there a correlation between the glass forming ability of a drug and its supersaturation propensity?

    Blaabjerg, L. I., Lindenberg, E., Löbmann, Korbinian, Grohganz, Holger & Rades, Thomas, 1 Mar 2018, In: International Journal of Pharmaceutics. 538, 1-2, p. 243-249

    Research output: Contribution to journalJournal articleResearchpeer-review

  205. Published

    The ability of two in vitro lipolysis models reflecting the human and rat gastro-intestinal conditions to predict the in vivo performance of SNEDDS dosing regimens

    Jorgensen, S. D. S., Al Sawaf, M., Graeser, K., Mu, Huiling, Mullertz, Anette & Rades, Thomas, Mar 2018, In: European Journal of Pharmaceutics and Biopharmaceutics. 124, p. 116-124

    Research output: Contribution to journalJournal articleResearchpeer-review

  206. Published

    On the role of salt formation and structural similarity of co-formers in co-amorphous drug delivery systems

    Wu, W., Löbmann, Korbinian, Rades, Thomas & Grohganz, Holger, 15 Jan 2018, In: International Journal of Pharmaceutics. 535, 1-2, p. 86-94

    Research output: Contribution to journalJournal articleResearchpeer-review

  207. Published

    Characterisation of pore structures of pharmaceutical tablets: A review

    Markl, D., Strobel, A., Schlossnikl, R., Bøtker, Johan Peter, Bawuah, P., Ridgway, C., Rantanen, Jukka, Rades, Thomas, Gane, P., Peiponen, K. & Zeitler, J. A., 5 Jan 2018, In: International Journal of Pharmaceutics. 538, 1, p. 188-214 27 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  208. Published

    A non-destructive method for quality control of the pellet distribution within a MUPS tablet by terahertz pulsed imaging

    Novikova, A., Markl, D., Axel Zeitler, J., Rades, Thomas & Leopold, C. S., Jan 2018, In: European Journal of Pharmaceutical Sciences. 111, p. 549-555

    Research output: Contribution to journalJournal articleResearchpeer-review

  209. Published

    Combining diagnostic methods for antimicrobial susceptibility testing – A comparative approach

    Klodzinska, S. N., Priemel, P. A., Rades, Thomas & Nielsen, Hanne Mørck, Jan 2018, In: Journal of Microbiological Methods. 144, p. 177-185

    Research output: Contribution to journalJournal articleResearchpeer-review

  210. Published

    Effect of composition of simulated intestinal media on the solubility of poorly soluble compounds investigated by design of experiments

    Madsen, C. M., Feng, K., Leithead, A., Canfield, N., Jørgensen, S. A., Mullertz, Anette & Rades, Thomas, Jan 2018, In: European Journal of Pharmaceutical Sciences. 111, p. 311-319 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  211. Published

    Hot Melt Extrusion as Solvent-Free Technique for a Continuous Manufacturing of Drug-Loaded Mesoporous Silica

    Genina, Natalja, Hadi, B. & Löbmann, Korbinian, Jan 2018, In: Journal of Pharmaceutical Sciences. 107, 1, p. 149-155

    Research output: Contribution to journalJournal articleResearchpeer-review

  212. Published

    Influence of PVP molecular weight on the microwave assisted in situ amorphization of indomethacin

    Doreth, M., Löbmann, Korbinian, Priemel, P., Grohganz, Holger, Taylor, R., Holm, R., Lopez de Diego, H. & Rades, Thomas, Jan 2018, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 122, p. 62-69

    Research output: Contribution to journalJournal articleResearchpeer-review

  213. Published

    Using Potentiometric Free Drug Sensors to Determine the Free Concentration of Ionizable Drugs in Colloidal Systems

    Tran, T., Chakraborty, A., Xi, X., Bohets, H., Cornett, Claus, Tsinman, K., Rades, Thomas & Mullertz, Anette , Jan 2018, In: Journal of Pharmaceutical Sciences. 107, 1, p. 103-112

    Research output: Contribution to journalJournal articleResearchpeer-review

  214. Published

    Are phytosomes a superior nanodelivery system for the antioxidant rutin?

    Vu, H. T. H., Hook, S. M., Siqueira, S. D., Mullertz, Anette , Rades, Thomas & McDowell, A., 2018, In: International Journal of Pharmaceutics. 548, 1, p. 82-91 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  215. Published

    Characterization of the hydrodynamics in a miniaturized dissolution apparatus

    Johansson, Kristoffer Enøe, Plum, J., Mosleh, M., Madsen, C. M., Rades, Thomas & Mullertz, Anette , 2018, In: Journal of Pharmaceutical Sciences. 107, 4, p. 1095-1103 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  216. Published

    Development and characterization of clove oil nanoemulsions and self-microemulsifying drug delivery systems

    Kheawfu, K., Pikulkaew, S., Rades, Thomas, Mullertz, Anette & Okonogi, S., 2018, In: Journal of Drug Delivery Science and Technology. 46, p. 330-338 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  217. Published

    Drug nanocrystallisation within liposomes

    Li, T., Cipolla, D., Rades, Thomas & Boyd, B. J., 2018, In: Journal of Controlled Release. 288, p. 96-110 15 p.

    Research output: Contribution to journalReviewResearchpeer-review

  218. Published

    Formulation of self-nanoemulsifying drug delivery systems containing monoacyl phosphatidylcholine and Kolliphor® RH40 using experimental design

    Tran, T., Rades, Thomas & Mullertz, Anette , 2018, In: Asian Journal of Pharmaceutical Sciences. 13, p. 536-545

    Research output: Contribution to journalJournal articleResearchpeer-review

  219. Published

    Undesired co-amorphisation of indomethacin and arginine during combined storage at high humidity conditions

    Petry, I., Löbmann, Korbinian, Grohganz, Holger, Rades, Thomas & Leopold, C. S., 2018, In: International Journal of Pharmaceutics. 544, 1, p. 172-180 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  220. 2017
  221. Published

    Pharmaceutical and security applications of terahertz spectroscopy

    Zeitler, J. A., Rades, Thomas & Taday, P. F., 1 Jan 2017, Terahertz Spectroscopy: Principles and Applications. CRC Press, p. 299-324 26 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  222. Published

    Self-microemulsifying drug delivery system and nanoemulsion for enhancing aqueous miscibility of Alpinia galanga oil

    Khumpirapang, N., Pikulkaew, S., Mullertz, Anette , Rades, Thomas & Okonogi, S., 2017, In: PLOS ONE. 12, 11, 18 p., e0188848.

    Research output: Contribution to journalJournal articleResearchpeer-review

  223. 2016
  224. Published

    In Vivo Precipitation of Poorly Soluble Drugs from Lipid-Based Drug Delivery Systems

    Sassene, P. J., Michaelsen, M. H., Mosgaard, M. D., Klitgaard, Mette, Van Den Broek, E., Wasan, K. M., Mu, Huiling, Rades, Thomas & Mullertz, Anette , 3 Oct 2016, In: Molecular Pharmaceutics. 13, 10, p. 3417-3426 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  225. Published

    Principles of controlled release

    Perrie, Y., Rades, Thomas & Graeser, K., 15 Sep 2016, Drug Delivery: Fundamentals and Applications: Second Edition. CRC Press, p. 25-46 22 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  226. Published

    The administration route is decisive for the ability of the vaccine adjuvant CAF09 to induce antigen-specific CD8(+) T-cell responses: The immunological consequences of the biodistribution profile

    Schmidt, S. T., Khadke, S., Korsholm, K. S., Perrie, Y., Rades, Thomas, Andersen, P., Foged, Camilla & Christensen, D., 26 Aug 2016, In: Journal of controlled release : official journal of the Controlled Release Society. 239, p. 107-117 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  227. Published

    Poly(Alkyl Cyanoacrylate) nanoparticles for drug delivery and vaccine development

    Graf, A., Krauel-Göllner, K. & Rades, Thomas, 19 Apr 2016, Colloids in Drug Delivery. CRC Press, p. 99-136 38 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  228. Published

    Liposome-Based Adjuvants for Subunit Vaccines: Formulation Strategies for Subunit Antigens and Immunostimulators

    Schmidt, S. T., Foged, Camilla, Korsholm, K. S., Rades, Thomas & Christensen, D., 10 Mar 2016, In: Pharmaceutics. 8, 1, 22 p., 7.

    Research output: Contribution to journalReviewResearchpeer-review

  229. Published

    Evaluating Oral Drug Delivery Systems: Digestion Models.

    Berthelsen, R., Sassene, P., Rades, Thomas & Mullertz, Anette , 2016, Analytical Techniques in the Pharmaceutical Sciences. Springer, p. 753-771

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  230. Published

    Evaluating Oral Drug Delivery Systems: Dissolution Models.

    Berthelsen, R., Mullertz, Anette & Rades, Thomas, 2016, Analytical Techniques in the Pharmaceutical Sciences. Springer, p. 753-771

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  231. 2015
  232. Published

    Influence of Tableting on the Conformation and Thermal Stability of Trypsin as a Model Protein

    Klukkert, M., van de Weert, Marco, Fanø, M., Rades, Thomas & Leopold, C. S., 2015, In: Journal of Pharmaceutical Sciences. 104, 12, p. 4314–4321 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  233. Published

    Role of polymeric excipients in the stabilization of olanzapine when exposed to aqueous environments

    Paisana, M., Wahl, M., Pinto, J., Rades, Thomas (ed.), Grohganz, Holger (ed.) & Löbmann, Korbinian (ed.), 2015, In: Molecules. 20, 12, p. 22634-223282 200649.

    Research output: Contribution to journalJournal articleResearchpeer-review

  234. Published

    Subunit Vaccine Delivery: Advances in Delivery Science and Technology

    Foged, Camilla, Rades, Thomas, Perrie, Y. & Hook, S., 2015, New York.

    Research output: Book/ReportBookResearchpeer-review

  235. 2013
  236. Published

    Amorphous drugs and dosage forms

    Grohganz, Holger, Löbmann, Korbinian, Priemel, P., Tarp Jensen, K., Graeser, K., Strachan, C. & Rades, Thomas, 2013, In: Journal of Drug Delivery Science and Technology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  237. 2012
  238. Published

    Effect of different preparation methods on the dissolution behaviour of amorphous indomethacin

    Karmwar, P., Graeser, K., Gordon, K. C., Strachan, C. J. & Rades, Thomas, Feb 2012, In: European Journal of Pharmaceutics and Biopharmaceutics. 80, 2, p. 459-464 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  239. Published

    Determination of moisture content in relation to thermal behaviour and plasticization of Eudragit RLPO

    Pirayavaraporn, C., Rades, Thomas & Tucker, I. G., 17 Jan 2012, In: International Journal of Pharmaceutics. 422, 1-2, p. 68-74 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  240. Published

    Measurement of amorphous indomethacin stability with NIR and Raman spectroscopy

    Kao, J. Y., McGoverin, C. M., Graeser, K. A., Rades, Thomas & Gordon, K. C., Jan 2012, In: Vibrational Spectroscopy. 58, p. 19-26 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  241. Published

    Thermal degradation of amorphous glibenclamide

    Rehder, S., Sakmann, A., Rades, Thomas & Leopold, C. S., Jan 2012, In: European Journal of Pharmaceutics and Biopharmaceutics. 80, 1, p. 203-208 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  242. 2011
  243. Published

    Investigation of properties and recrystallisation behaviour of amorphous indomethacin samples prepared by different methods

    Karmwar, P., Graeser, K., Gordon, K. C., Strachan, C. J. & Rades, Thomas, 30 Sep 2011, In: International Journal of Pharmaceutics. 417, 1-2, p. 94-100 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  244. Published

    Preparation of phytantriol cubosomes by solvent precursor dilution for the delivery of protein vaccines

    Rizwan, S. B., Assmus, D., Boehnke, A., Hanley, T., Boyd, Ben, Rades, Thomas & Hook, S., Sep 2011, In: European Journal of Pharmaceutics and Biopharmaceutics. 79, 1, p. 15-22 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  245. Published

    Non-destructive quantification of pharmaceutical tablet coatings using terahertz pulsed imaging and optical coherence tomography

    Zhong, S., Shen, Y. C., Ho, L., May, R. K., Zeitler, J. A., Evans, M., Taday, P. F., Pepper, M., Rades, Thomas, Gordon, K. C., Mller, R. & Kleinebudde, P., Mar 2011, In: Optics and Lasers in Engineering. 49, 3, p. 361-365 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  246. 2010
  247. Published

    The role of configurational entropy in amorphous systems

    Graeser, K. A., Patterson, J. E., Zeitler, J. A. & Rades, Thomas, Jun 2010, In: Pharmaceutics. 2, 2, p. 224-244 21 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  248. Published

    From Water to Ice: Investigation of the Effect of Ice Crystal Reduction on the Stability of Frozen Large Unilamellar Vesicles

    Siow, L. F., Rades, Thomas & Lim, M. H., 14 May 2010, Water Properties in Food, Health, Pharmaceutical and Biological Systems: ISOPOW 10. Wiley-Blackwell, p. 551-562 12 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  249. Published

    Physical Changes in Confectionery Products Caused by the Availability of Water, with a Special Focus on Lactitol Crystallization

    Lim, M. H., Lampen, B., Siow, L. F. & Rades, Thomas, 14 May 2010, Water Properties in Food, Health, Pharmaceutical and Biological Systems: ISOPOW 10. Wiley-Blackwell, p. 271-282 12 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  250. Published

    Deeper insight into the drug release mechanisms in Eudragit RL-based delivery systems

    Glaessl, B., Siepmann, F., Tucker, I., Rades, Thomas & Siepmann, J., 15 Apr 2010, In: International Journal of Pharmaceutics. 389, 1-2, p. 139-146 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  251. Published

    Rapid and specific high-performance liquid chromatography for the in vitro quantification of D-Lys6-GnRH in a microemulsion-type formulation in the presence of peptide oxidation products

    Kafka, A. P., Rades, Thomas & McDowell, A., Feb 2010, In: Biomedical Chromatography. 24, 2, p. 132-139 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  252. Published

    Mathematical modeling of drug release from Eudragit RS-based delivery systems

    Glaessl, B., Siepmann, F., Tucker, I., Rades, Thomas & Siepmann, J., 2010, In: Journal of Drug Delivery Science and Technology. 20, 2, p. 127-133 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  253. 2009
  254. Published

    Polymeric nanoparticles as an oral delivery system for biocontrol agents for the brushtail possum (trichosurus vulpecula)

    McDowell, A., Rades, Thomas, Tucker, I. G. & McLeod, B. J., Dec 2009, In: New Zealand Veterinary Journal. 57, 6, p. 370-377 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  255. Published

    Advances in lipid-based subunit vaccine formulations

    Myschik, J., Rades, Thomas & Hook, S., 2009, In: Current Immunology Reviews.

    Research output: Contribution to journalJournal articleResearchpeer-review

  256. Published

    Characterisation of quaternary polymethacrylate films containing tartaric acid, metoprolol free base or metoprolol tartrate

    Glaessl, B., Siepmann, F., Tucker, I., Siepmann, J. & Rades, Thomas, 2009, In: European Journal of Pharmaceutics and Biopharmaceutics.

    Research output: Contribution to journalJournal articleResearchpeer-review

  257. Published

    Effects of some terpenes on the in vitro permeation of LHRH through newborn pig skin

    Songkro, S., Rades, Thomas & Becket, G., 2009, In: Pharmazie.

    Research output: Contribution to journalJournal articleResearchpeer-review

  258. 2007
  259. Published

    Applications of Raman spectroscopy in aqueous environments

    Sandler, N., Savolainen, M., Saupe, A., Strachan, C. & Rades, Thomas, 2007, In: Pharmaceutical Technology Europe.

    Research output: Contribution to journalJournal articleResearch

  260. Published

    Cage-like complexes formed by DOTAP, Quil-A and cholesterol

    Lendemans, D. G., Egert, A. M., Hook, S. & Rades, Thomas, 2007, In: International Journal of Pharmaceutics.

    Research output: Contribution to journalJournal articleResearchpeer-review

  261. Published

    Characterisation of bicontinuous cubic liquid crystalline systems of phytantriol and water using cryo field emission scanning electron microscopy (cryo FESEM)

    Rizwan, S. B., Dong, Y., Boyd, Ben, Rades, Thomas & Hook, S., 2007, In: Micron.

    Research output: Contribution to journalJournal articleResearchpeer-review

  262. Published

    Nonlinear optics as a method for materials characterisation

    Lee, C. J., Strachan, C. J., Rades, Thomas & Manson, P. J., 2007

    Research output: Book/ReportBookResearchpeer-review

  263. Published

    The influence of various excipients on the conversion kinetics of carbamazepine polymorphs in aqueous suspension

    Tian, F., Saville, D. J., Gordon, K. C., Strachan, C. J., Zeitler, J. A., Sandler, N. & Rades, Thomas, 2007, In: Journal of Pharmacy and Pharmacology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  264. Published

    Time-resolved terahertz spectroscopy: Polymorphic solid state phase transitions in carbamazepine

    Axel Zeitler, J., Taday, P. F., Gordon, K. C., Pepper, M. & Rades, Thomas, 2007, IRMMW-THz2007 - Conference Digest of the Joint 32nd International Conference on Infrared and Millimetre Waves, and 15th International Conference on Terahertz Electronics.

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

  265. 2006
  266. Published

    Solubilisation of soybean oil in microemulsions using various surfactants

    Flanagan, J., Kortegaard, K., Neil Pinder, D., Rades, Thomas & Singh, H., Mar 2006, In: Food Hydrocolloids. 20, 2-3 SPEC. ISS., p. 253-260 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  267. Published

    Understanding the influence of polymorphism on phonon spectra: Lattice dynamics calculations and terahertz spectroscopy of carbamazepine

    Day, G. M., Zeitler, J. A., Jones, W., Rades, Thomas & Taday, P. F., 12 Jan 2006, In: Journal of Physical Chemistry B. 110, 1, p. 447-456 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  268. Published

    Analysis of lecithin-cholesterol mixtures using Raman spectroscopy

    Tantipolphan, R., Rades, Thomas, Strachan, C. J., Gordon, K. C. & Medlicott, N. J., 2006, In: Journal of Pharmaceutical and Biomedical Analysis.

    Research output: Contribution to journalJournal articleResearchpeer-review

  269. Published

    Application of pharmaceutical drug delivery for biological control of the common brushtail possum in New Zealand: A review

    McDowell, A., McLeod, B. J., Rades, Thomas & Tucker, I. G., 2006, In: Wildlife Research.

    Research output: Contribution to journalJournal articleResearchpeer-review

  270. Published

    Characterisation of microemulsions containing orange oil with water and propylene glycol as hydrophilic components

    Yotsawimonwat, S., Okonoki, S., Krauel, K., Sirithunyalug, J., Sirithunyalug, B. & Rades, Thomas, 2006, In: Pharmazie.

    Research output: Contribution to journalJournal articleResearchpeer-review

  271. Published

    Characterisation of microstructures formed in isopropyl palmitate/water/Aerosol®OT: 1-butanol (2:1) system

    Boonme, P., Krauel, K., Graf, A., Rades, Thomas & Junyaprasert, V. B., 2006, In: Pharmazie.

    Research output: Contribution to journalJournal articleResearchpeer-review

  272. Published

    Characterizing the conversion kinetics of carbamazepine polymorphs to the dihydrate in aqueous suspension using Raman spectroscopy

    Tian, F., Zeitler, J. A., Strachan, C. J., Saville, D. J., Gordon, K. C. & Rades, Thomas, 2006, In: Journal of Pharmaceutical and Biomedical Analysis.

    Research output: Contribution to journalJournal articleResearchpeer-review

  273. Published

    Effect of milling conditions on the solid-state conversion of ranitidine hydrochloride form 1

    Chieng, N., Zujovic, Z., Bowmaker, G., Rades, Thomas & Saville, D., 2006, In: International Journal of Pharmaceutics.

    Research output: Contribution to journalJournal articleResearchpeer-review

  274. Published

    On the dilution behaviour of immuno-stimulating complexes (ISCOMs)

    Lendemans, D. G., Egert, A. M., Myschik, J., Hook, S. & Rades, Thomas, 2006, In: Pharmazie.

    Research output: Contribution to journalJournal articleResearchpeer-review

  275. Published

    Quantification of binary polymorphic mixtures of ranitidine hydrochloride using NIR spectroscopy

    McGoverin, C. M., Ho, L. C. H., Zeitler, J. A., Strachan, C. J., Gordon, K. C. & Rades, Thomas, 2006, In: Vibrational Spectroscopy.

    Research output: Contribution to journalJournal articleResearchpeer-review

  276. Published

    Solid lipid nanoparticles

    Saupe, A. & Rades, Thomas, 2006

    Research output: Book/ReportBookResearchpeer-review

  277. Published

    Terahertz applications for the analysis of solid dosage forms

    Strachan, C. J., Ho, L., Zeitler, J. A., Rantanen, Jukka, Rades, Thomas & Gordon, K. C., 2006, In: Pharmaceutical Technology Europe.

    Research output: Contribution to journalJournal articleResearch

  278. Published

    The influence of silica nanoparticles on the preparation and stability of O/W emulsions

    Eskandar, N. G., Simovic, S., Saupe, A., Rades, Thomas & Prestidge, C. A., 2006, Proceedings of the 2006 International Conference on Nanoscience and Nanotechnology, ICONN.

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

  279. Published

    Visualizing the conversion of carbamazepine in aqueous suspension with and without the presence of excipients: A single crystal study using SEM and Raman microscopy

    Tian, F., Sandler, N., Gordon, K. C., McGoverin, C. M., Reay, A., Strachan, C. J., Saville, D. J. & Rades, Thomas, 2006, In: European Journal of Pharmaceutics and Biopharmaceutics.

    Research output: Contribution to journalJournal articleResearchpeer-review

  280. Published

    W/O microemulsions for ocular delivery: Evaluation of ocular irritation and precorneal retention

    Alany, R. G., Rades, Thomas, Nicoll, J., Tucker, I. G. & Davies, N. M., 2006, In: Journal of Controlled Release.

    Research output: Contribution to journalJournal articleResearchpeer-review

  281. 2005
  282. Published

    Using different structure types of microemulsions for the preparation of poly(alkylcyanoacrylate) nanoparticles by interfacial polymerization

    Krauel, K., Davies, N. M., Hook, S. & Rades, Thomas, 18 Aug 2005, In: Journal of Controlled Release. 106, 1-2, p. 76-87 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  283. Published

    Lipid based particulate formulations for the delivery of antigen

    Copland, M. J., Rades, Thomas, Davies, N. M. & Baird, M. A., Apr 2005, In: Immunology and Cell Biology. 83, 2, p. 97-105 9 p.

    Research output: Contribution to journalReviewResearchpeer-review

  284. Published

    Using terahertz pulsed spectroscopy to quantify pharmaceutical polymorphism and crystallinity

    Strachan, C. J., Taday, P. F., Newnham, D. A., Gordon, K. C., Zeitler, J. A., Pepper, M. & Rades, Thomas, Apr 2005, In: Journal of Pharmaceutical Sciences. 94, 4, p. 837-846 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  285. Published

    Determination of the optical second harmonic response of pharmaceutical solid-solid mixtures

    Strachan, C. J., Rades, Thomas & Lee, C. J., 2005, In: Optics and Lasers in Engineering.

    Research output: Contribution to journalJournal articleResearchpeer-review

  286. Published

    Dose-related effects of lauric acid on antropyloroduodenal motility, gastrointestinal hormone release, appetite, and energy intake in healthy men

    Little, T. J., Feltrin, K. L., Horowitz, M., Smout, A. J. P. M., Rades, Thomas, Meyer, J. H., Pilichiewicz, A. N., Wishart, J. & Feinle-Bisset, C., 2005, In: American Journal of Physiology - Regulatory Integrative and Comparative Physiology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  287. Published

    Temperature dependent terahertz pulsed spectroscopy of carbamazepine

    Zeitler, J. A., Newnham, D. A., Taday, P. F., Strachan, C. J., Pepper, M., Gordon, K. C. & Rades, Thomas, 2005, In: Thermochimica Acta.

    Research output: Contribution to journalJournal articleResearchpeer-review

  288. 2004
  289. Published

    Influence of hydrogenated starch hydrolysates on the glass transition and crystallisation of sugar alcohols

    McFetridge, J., Rades, Thomas & Lim, M., Jun 2004, In: Food Research International. 37, 5, p. 409-415 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  290. Published

    Using terahertz pulsed spectroscopy to study crystallinity of pharmaceutical materials

    Strachan, C. J., Rades, Thomas, Newnham, D. A., Gordon, K. C., Pepper, M. & Taday, P. F., 21 May 2004, In: Chemical Physics Letters. 390, 1-3, p. 20-24 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  291. Published

    A comparison of pseudo-ternary diagrams of aqueous mixtures of Quil A, cholesterol and phospholipid prepared by lipid-film hydration and dialysis

    Demana, P. H., Davies, N. M., Berger, B., Vosgerau, U. & Rades, Thomas, May 2004, In: Journal of Pharmacy and Pharmacology. 56, 5, p. 573-580 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  292. Published

    A theoretical and spectroscopic study of carbamazepine polymorphs

    Strachan, C. J., Howell, S. L., Rades, Thomas & Gordon, K. C., May 2004, In: Journal of Raman Spectroscopy. 35, 5, p. 401-408 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  293. Published

    Quantitative analysis of polymorphic mixtures of carbamazepine by Raman spectroscopy and principal components analysis

    Strachan, C. J., Pratiwi, D., Gordon, K. C. & Rades, Thomas, May 2004, In: Journal of Raman Spectroscopy. 35, 5, p. 347-352 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  294. Published

    Determination of unfrozen matrix concentrations at low temperatures using stepwise DSC

    Liesebach, J., Lim, M. & Rades, Thomas, 19 Feb 2004, In: Thermochimica Acta. 411, 1, p. 43-51 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  295. Published

    Uptake of antigen encapsulated in polyethylcyanoacrylate nanoparticles by D1-dendritic cells

    Pitaksuteepong, T., Davies, N. M., Baird, M. & Rades, Thomas, Feb 2004, In: Pharmazie. 59, 2, p. 134-142 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  296. Published

    Entrapment of bioactive molecules in poly (alkylcyanoacrylate) nanoparticles

    Krauel, K., Pitaksuteepong, T., Davies, N. M. & Rades, Thomas, 2004, In: American Journal of Drug Delivery. 2, 4, p. 251-259 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  297. Published
  298. 2003
  299. Published

    Comparison of the Gordon-Taylor and Couchman-Karasz equations for prediction of the glass transition temperature of glass solutions of drug and polyvinylpyrrolidone prepared by melt extrusion

    Forster, A., Hempenstall, J. & Rades, Thomas, Nov 2003, In: Pharmazie. 58, 11, p. 838-839 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  300. Published

    The effects of p-menthane monoterpenes and related compounds on the percutaneous absorption of propranolol hydrochloride across newborn pig skin: II. Infrared spectroscopic and thermal analysis investigations

    Songkro, S., Becket, G. & Rades, Thomas, Nov 2003, In: S.T.P. Pharma Sciences. 13, 6, p. 397-404 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  301. Published

    Investigation of the physical stability of amorphous drug and drug/polymer melts using variable temperature solid state NMR

    Forster, A., Apperley, D., Hempenstall, J., Lancaster, R. & Rades, Thomas, Oct 2003, In: Pharmazie. 58, 10, p. 761-762 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  302. Published

    The effects of p-menthane monoterpenes and related compounds on the percutaneous absorption of propanolol hydrochloride across newborn pig skin I. In vitro skin permeation and retention studies

    Songkro, S., Rades, Thomas & Becket, G., Sep 2003, In: S.T.P. Pharma Sciences. 13, 5, p. 349-357 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  303. Published

    A new method for the determination of the unfrozen matrix concentration and the maximal freeze-concentration

    Liesebach, J., Rades, Thomas & Lim, M., 19 May 2003, In: Thermochimica Acta. 401, 2, p. 159-168 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  304. Published

    Investigation of newborn pig skin as an in vitro animal model for transdermal drug delivery

    Songkro, S., Purwo, Y., Becket, G. & Rades, Thomas, Mar 2003, In: S.T.P. Pharma Sciences. 13, 2, p. 133-139 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  305. Published

    Liposomal delivery of antigen to human dendritic cells

    Copland, M. J., Baird, M. A., Rades, Thomas, McKenzie, J. L., Becker, B., Reck, F., Tyler, P. C. & Davies, N. M., 14 Feb 2003, In: Vaccine. 21, 9-10, p. 883-890 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  306. Published

    Physical stability and enthalpy relaxation of drug-hydroxypropyl methylcellulose phthalate solvent change co-precipitates

    Sertsou, G., Butler, J., Hempenstall, J. & Rades, Thomas, 1 Jan 2003, In: Journal of Pharmacy and Pharmacology. 55, 1, p. 35-41 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  307. 2002
  308. Published

    Quantitative analysis of polymorphic mixtures of ranitidine hydrochloride by raman spectroscopy and principal components analysis

    Pratiwi, D., Paul Fawcett, J., Gordon, K. C. & Rades, Thomas, Nov 2002, In: European Journal of Pharmaceutics and Biopharmaceutics. 54, 3, p. 337-341 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  309. Published

    Selection of suitable drug and excipient candidates to prepare glass solutions by melt extrusion for immediate release oral formulations

    Forster, A., Rades, Thomas & Hempenstall, J., 1 Oct 2002, In: Pharmaceutical Technology Europe. 14, 10, p. 27-28+31

    Research output: Contribution to journalReviewResearchpeer-review

  310. Published

    Effects of formulation variables on characteristics of poly (ethylcyanoacrylate) nanocapsules prepared from w/o microemulsions

    Watnasirichaikul, S., Rades, Thomas, Tucker, I. G. & Davies, N. M., 20 Mar 2002, In: International Journal of Pharmaceutics. 235, 1-2, p. 237-246 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  311. Published

    Effects of meal consistency and ingested fluid volume on the intragastric distribution of a drug model in humans - A magnetic resonance imaging study

    Faas, H., Steingoetter, A., Feinle, C., Rades, Thomas, Lengsfeld, H., Boesiger, P., Fried, M. & Schwizer, W., 2002, In: Alimentary Pharmacology and Therapeutics. 16, 2, p. 217-224 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  312. 2001
  313. Published

    Selection of excipients for melt extrusion with two poorly water-soluble drugs by solubility parameter calculation and thermal analysis

    Forster, A., Hempenstall, J., Tucker, I. & Rades, Thomas, 11 Sep 2001, In: International Journal of Pharmaceutics. 226, 1-2, p. 147-161 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  314. Published

    Characterization of glass solutions of poorly water-soluble drugs produced by melt extrusion with hydrophilic amorphous polymers

    Forster, A., Hempenstall, J. & Rades, Thomas, 2001, In: Journal of Pharmacy and Pharmacology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  315. Published

    Characterizing colloidal structures of pseudoternary phase diagrams formed by oil/water/amphiphile systems

    Alany, R. G., Tucker, I. G., Davies, N. M. & Rades, Thomas, 2001, In: Drug Development and Industrial Pharmacy.

    Research output: Contribution to journalJournal articleResearchpeer-review

  316. Published

    Determination of polymorphic forms of ranitidine-HCl by DRIFTS and XRPD

    Agatonovic-Kustrin, S., Rades, Thomas, Wu, V., Saville, D. & Tucker, I. G., 2001, In: Journal of Pharmaceutical and Biomedical Analysis.

    Research output: Contribution to journalJournal articleResearchpeer-review

  317. Published

    Emulsions as oral moisturisers for the treatment of severe xerostomia

    Lewisham, K. M., Ferguson, M. M. & Rades, Thomas, 2001, In: Pharmazie.

    Research output: Contribution to journalJournal articleResearchpeer-review

  318. Published

    Fat digestion modulates gastrointestinal sensations induced by gastric distention and duodenal lipid in humans

    Feinle, C., Rades, Thomas, Otto, B. & Fried, M., 2001, In: Gastroenterology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  319. Published

    Monitoring the intragastric distribution of a colloidal drug carrier model by magnetic resonance imaging460

    Faas, H., Schwizer, W., Feinle, C., Lengsfeld, H., De Smidt, C., Boesiger, P., Fried, M. & Rades, Thomas, 2001, In: Pharmaceutical Research.

    Research output: Contribution to journalJournal articleResearchpeer-review

  320. Published

    The potential of small-scale fusion experiments and the Gordon-Taylor equation to predict the suitability of drug/polymer blends for melt extrusion

    Forster, A., Hempenstall, J., Tucker, I. & Rades, Thomas, 2001, In: Drug Development and Industrial Pharmacy.

    Research output: Contribution to journalJournal articleResearchpeer-review

  321. 2000
  322. Published

    Direct detection of dissolution of <sup>14</sup>C-labeled compounds into an oil phase by the fat scintillation proximity method

    De Smidt, P. C. & Rades, Thomas, 2000, In: International Journal of Pharmaceutics.

    Research output: Contribution to journalJournal articleResearchpeer-review

  323. Published

    Effects of alcohols and diols on the phase behaviour of quaternary systems

    Alany, R. G., Rades, Thomas, Agatonovic-Kustrin, S., Davies, N. M. & Tucker, I. G., 2000, In: International Journal of Pharmaceutics.

    Research output: Contribution to journalJournal articleResearchpeer-review

  324. 1997
  325. Published

    Characterization of a commercial liposome spray

    Rades, Thomas, Gerke, A., Schütze, W. & Müller-Goymann, C. C., 1997, In: Pharmazie.

    Research output: Contribution to journalJournal articleResearchpeer-review

  326. Published

    Electron and light microscopical investigation of defect structures in mesophases of pharmaceutical substances

    Rades, Thomas & Müller-Goymann, C. C., 1997, In: Colloid and Polymer Science.

    Research output: Contribution to journalJournal articleResearchpeer-review

  327. Published

    Investigations on the micellisation behaviour of fenoprofen sodium

    Rades, Thomas & Müller-Goymann, C. C., 1997, In: International Journal of Pharmaceutics.

    Research output: Contribution to journalJournal articleResearchpeer-review

  328. 1996
  329. Published

    Thermal behaviour and solubility of fenoprofen calcium

    Rades, Thomas, Padmadisastra, Y. & Müller-Goymann, C. C., 1996, In: Pharmazie.

    Research output: Contribution to journalJournal articleResearchpeer-review

  330. 1994
  331. Published

    Influence of amphiphilic substances on the coil-helix transformation of gelatin

    Rades, Thomas, Schutze, W., Hirsch, R. & Muller-Goymann, C. C., 1994, In: Pharmazie.

    Research output: Contribution to journalJournal articleResearchpeer-review

  332. Published

    Melting behaviour and thermotropic mesomorphism of fenoprofen salts

    Rades, Thomas & Muller-Goymann, C. C., 1994, In: European Journal of Pharmaceutics and Biopharmaceutics.

    Research output: Contribution to journalJournal articleResearchpeer-review

  333. 1993
  334. Published

    Interactions between gelatin and amphiphilic substances

    Rades, Thomas, Schutze, W. & Muller-Goymann, C. C., 1993, In: Pharmazie.

    Research output: Contribution to journalJournal articleResearchpeer-review