- 2022
- Published
Effects of polymer addition on the non-strongly interacting binary co-amorphous system carvedilol-tryptophan
Wang, Y., Grohganz, Holger & Rades, Thomas, 2022, In: International Journal of Pharmaceutics. 617, 9 p., 121625.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Elucidating Pathway and Anesthetic Mechanism of Action of Clove Oil Nanoformulations in Fish
Kheawfu, K., Pikulkaew, S., Wellendorph, Petrine, Jørgensen, Louise von Gersdorff, Rades, Thomas, Mullertz, Anette & Okonogi, S., 2022, In: Pharmaceutics. 14, 5, 13 p., 919.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Elucidating the Dehydration Mechanism of Nitrofurantoin Monohydrate II Using Low-Frequency Raman Spectroscopy
Remoto, P. J. G., Bērziņš, Kārlis, Fraser-Miller, S. J., Korter, T. M., Rades, Thomas, Rantanen, Jukka & Gordon, K. C., 2022, In: Crystal Growth and Design. 22, 4, p. 2733-2741Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hyperthermia-Induced In Situ Drug Amorphization by Superparamagnetic Nanoparticles in Oral Dosage Forms
Ansari, S. R., Hempel, N. J., Asad, S., Svedlindh, P., Bergström, C. A. S., Löbmann, Korbinian & Teleki, A., 2022, In: ACS Applied Materials and Interfaces. 14, 19, p. 21978–21988Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of Molecular Surface Diffusion on the Physical Stability of Co-Amorphous Systems
Liu, J., Hwu, E., Bannow, J., Grohganz, Holger & Rades, Thomas, 2022, In: Molecular Pharmaceutics. 19, 4, p. 1183-1190Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of oral gavage technique of drug-containing microcontainers on the gastrointestinal transit and absorption in rats
Kristensen, M. N., Rades, Thomas, Boisen, A. & Mullertz, Anette , 2022, In: International Journal of Pharmaceutics. 618, 121630.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In Situ Transformation of Electrospun Nanofibers into Nanofiber-Reinforced Hydrogels
Martin, A., Nyman, J. N., Reinholdt, R., Cai, Jun, Gürtler, Anna-Lena, van der Plas, Mariena J.A., Malmsten, Martin, Rades, Thomas & Heinz, Andrea, 2022, In: Nanomaterials. 12, 14, 2437.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of Water on Amorphous Lidocaine
Xu, X., Grohganz, Holger & Rades, Thomas, 2022, In: Molecular Pharmaceutics. 19, 9, p. 3199–3205Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Low-Frequency Raman Spectroscopy as an Avenue to Determine the Transition Temperature of β- and γ-Relaxation in Pharmaceutical Glasses
Bērziņš, Kārlis, Fraser-Miller, S. J., Rades, Thomas & Gordon, K. C., 2022, In: Analytical Chemistry. 94, 23, p. 8241-8248Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pharmaceutical Technology in Europe
Siepmann, J., Basit, A. & Rades, Thomas, 2022, In: International Journal of Pharmaceutics. 613, 1 p., 121441.Research output: Contribution to journal › Editorial › Research
- Published
Physico-chemical characterization of aspirated and simulated human gastric fluids to study their influence on the intrinsic dissolution rate of cinnarizine
Pedersen, P. B., Berthelsen, R., Rades, Thomas, Jørgensen, S. A., Vilmann, Peter, Bar-Shalom, Daniel, Baldursdottir, S. & Mullertz, Anette , 2022, In: International Journal of Pharmaceutics. 622, 7 p., 121856.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Simultaneous quantification of multiple RNA cargoes co-loaded into nanoparticle-based delivery systems
Lokras, Abhijeet, Chakravarty, A., Rades, Thomas, Christensen, D., Franzyk, Henrik, Thakur, A. & Foged, Camilla, 2022, In: International Journal of Pharmaceutics. 626, 13 p., 122171.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Solventless amorphization and pelletization using a high shear granulator. Part I; feasibility study using indomethacin
Kondo, K. & Rades, Thomas, 2022, In: European Journal of Pharmaceutics and Biopharmaceutics. 181, p. 147-158Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Solventless amorphization and pelletization using a high shear granulator. Part II; Preparation of co-amorphous mixture-layered pellets using indomethacin and arginine
Kondo, K. & Rades, Thomas, 2022, In: European Journal of Pharmaceutics and Biopharmaceutics. 181, p. 183-194Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Stabilizing Mechanisms of β-Lactoglobulin in Amorphous Solid Dispersions of Indomethacin
Kabedev, A., Zhuo, Xuezhi, Leng, D., Foderà, Vito, Zhao, M., Larsson, P., Bergström, C. A. S. & Löbmann, Korbinian, 2022, In: Molecular Pharmaceutics. 19, 11, p. 3922–3933Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Supersaturated amorphous solid dispersions of celecoxib prepared in situ by microwave irradiation
Holm, T. P., Knopp, Matthias Manne, Berthelsen, R. & Löbmann, Korbinian, 2022, In: International Journal of Pharmaceutics. 626, 8 p., 122115.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Binding of Alpinia galanga Oil and Its Nanoemulsion to Mammal GABA(A) Receptors Using Rat Cortical Membranes and an In Silico Modeling Platform
Khumpirapang, N., Suknuntha, K., Wongrattanakamon, P., Jiranusornkul, S., Anuchapreeda, S., Wellendorph, Petrine, Mullertz, Anette , Rades, Thomas & Okonogi, S., 2022, In: Pharmaceutics. 14, 3, 15 p., 650.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Topical niclosamide (ATx201) reduces Staphylococcus aureus colonization and increases Shannon diversity of the skin microbiome in atopic dermatitis patients in a randomized, double-blind, placebo-controlled Phase 2 trial
Weiss, A., Delavenne, E., Matias, C., Lagler, H., Simon, D., Li, P., Hansen, J. U., Dos Santos, T. P., Jana, B., Priemel, P., Bangert, C., Bauer, M., Eberl, S., Nussbaumer-Pröll, A., Anne Österreicher, Z., Matzneller, P., Quint, T., Weber, M., Nielsen, H. M., Rades, T. & 17 others, , 2022, In: Clinical and Translational Medicine. 12, 5, e790.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Zein-polycaprolactone core-shell nanofibers for wound healing
Martin, A., Cai, Jun, Gürtler, Anna-Lena, van der Plas, Mariena J.A., Malmsten, Martin, Rades, Thomas & Heinz, Andrea, 2022, In: International Journal of Pharmaceutics. 621, 10 p., 121809.Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
The effect of the molecular weight of polyvinylpyrrolidone and the model drug on laser-induced in situ amorphization
Hempel, N. J., Merkl, P., Knopp, Matthias Manne, Berthelsen, R., Teleki, A., Hansen, A. K., Sotiriou, G. A. & Löbmann, Korbinian, Jul 2021, In: Molecules. 26, 13, 13 p., 4035.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Multivariate Approach for the Determination of the Optimal Mixing Ratio of the Non-Strong Interacting Co-Amorphous System Carvedilol-Tryptophan
Di, Rong, Liu, J., Grohganz, Holger & Rades, Thomas, 2021, In: Molecules. 26, 4, 8 p., 801.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Co-Amorphous Drug Formulations in Numbers: Recent Advances in Co-Amorphous Drug Formulations with Focus on Co-Formability, Molar Ratio, Preparation Methods, Physical Stability, In Vitro and In Vivo Performance, and New Formulation Strategies
Liu, J., Grohganz, Holger, Löbmann, Korbinian, Rades, Thomas & Hempel, N., 2021, In: Pharmaceutics. 13, 3, 43 p., 389.Research output: Contribution to journal › Review › Research
- Published
Combined Effect of the Preparation Method and Compression on the Physical Stability and Dissolution Behavior of Melt-Quenched Amorphous Celecoxib
Bērziņš, Kārlis, Fraser-Miller, S. J., Di, Rong, Liu, J., Peltonen, L., Strachan, C. J., Rades, Thomas & Gordon, K. C., 2021, In: Molecular Pharmaceutics. 18, 3, p. 1408-1418Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparison of co-former performance in co-amorphous formulations: Single amino acids, amino acid physical mixtures, amino acid salts and dipeptides as co-formers
Wu, W., Grohganz, Holger, Rades, Thomas & Löbmann, Korbinian, 2021, In: European Journal of Pharmaceutical Sciences. 156, 8 p., 105582.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Deliquescence Behavior of Deep Eutectic Solvents
Palmelund, H., Rantanen, Jukka & Löbmann, Korbinian, 2021, In: Applied Sciences. 11, 9 p., 1601.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Design and optimization of self-nanoemulsifying drug delivery systems of clove oil for efficacy enhancement in fish anesthesia
Kheawfu, Pikulkaew, Rades, Thomas, Mullertz, Anette , Jørgensen, Louise von Gersdorff & Okonogi, 2021, In: Journal of Drug Delivery Science and Technology. 61, 9 p., 102241.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Design of a self-unfolding delivery concept for oral administration of macromolecules
Jørgensen, J. R., Thamdrup, L. H. E., Kamguyan, K., Nielsen, L. H., Nielsen, Hanne Mørck, Boisen, A., Rades, Thomas & Mullertz, Anette , 2021, In: Journal of Controlled Release. 329, p. 948-954Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Development of Self-Nanoemulsifying Drug Delivery Systems Containing 4-Allylpyrocatechol for Treatment of Oral Infections Caused by Candida albicans
Okonogi, S., Phumat, P., Khongkhunthian, S., Chaijareenont, P., Rades, Thomas & Mullertz, Anette , 2021, In: Pharmaceutics. 13, 2, 16 p., 167.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Enabling formulations of aprepitant: in vitro and in vivo comparison of nanocrystalline, amorphous and deep eutectic solvent based formulations
Palmelund, H., Eriksen, J. B., Bauer-Brandl, A., Rantanen, Jukka & Löbmann, Korbinian, 2021, In: International Journal of Pharmaceutics: X. 3, 100083.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exploring the Impact of Intestinal Fluid Components on the Solubility and Supersaturation of Danazol
Madsen, C. M., Plum, J., Hens, B., Augustijns, P., Mullertz, Anette & Rades, Thomas, 2021, In: Journal of Pharmaceutical Sciences. 110, 6, p. 2479-2488 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Formulation optimization, anesthetic activity, skin permeation, and transportation pathway of Alpinia galanga oil SNEDDS in zebrafish (Danio rerio)
Khumpirapang, N., Jørgensen, Louise von Gersdorff, Mullertz, Anette , Rades, Thomas & Okonogi, S., 2021, In: European Journal of Pharmaceutics and Biopharmaceutics. 165, p. 193-202 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Interactions of Cell-Penetrating Peptide-Modified Nanoparticles with Cells Evaluated Using Single Particle Tracking
Streck, S., Bohr, S. S., Birch, D., Rades, Thomas, Hatzakis, Nikos, McDowell, A. & Nielsen, Hanne Mørck, 2021, In: ACS Applied Bio Materials. 4, 4, p. 3155-3165 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Investigating to Optimal Ratio between Drug and Co-Former in Co-Amorphous Systems
Rades, Thomas, 2021, In: Proceedings. 78, 1, 1 p., 27.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Investigation into the role of the polymer in enhancing microwave-induced in situ amorphization
Qiang, W., Löbmann, Korbinian, Knopp, Matthias Manne, McCoy, C. P., Andrews, G. P. & Zhao, M., 2021, In: International Journal of Pharmaceutics. 609, 8 p., 121157.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Investigation on Formulation Strategies to Mitigate Compression-Induced Destabilization in Supersaturated Celecoxib Amorphous Solid Dispersions
Bērziņš, Kārlis, Fraser-Miller, S. J., Walker, G. F., Rades, Thomas & Gordon, K. C., 2021, In: Molecular Pharmaceutics. 18, 10, p. 3882–3893Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mechanochemical N-Chlorination Reaction of Hydantoin: In Situ Real-Time Kinetic Study by Powder X-ray Diffraction and Raman Spectroscopy
Batista Martins, Inês Catarina, Carta, M., Haferkamp, S., Feiler, T., Delogu, F., Colacino, E. & Emmerling, F., 2021, In: ACS Sustainable Chemistry & Engineering. 9, 37, p. 12591-12601Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Microwave induced in situ amorphisation facilitated by crystalline hydrates
Holm, T. P., Knopp, M. M., Löbmann, Korbinian & Berthelsen, R., 2021, In: European Journal of Pharmaceutical Sciences. 163, 9 p., 105858.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Microwave-Induced in Situ Drug Amorphization Using a Mixture of Polyethylene Glycol and Polyvinylpyrrolidone
Hempel, N. J., Knopp, Matthias Manne, Zeitler, J. A., Berthelsen, R. & Löbmann, Korbinian, 2021, In: Journal of Pharmaceutical Sciences. 110, 9, p. 3221-3229Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Monitoring the Isothermal Dehydration of Crystalline Hydrates Using Low-Frequency Raman Spectroscopy
Robert, C., Fraser-Miller, S. J., Bērziņš, Kārlis, Okeyo, P. O., Rantanen, Jukka, Rades, Thomas & Gordon, K. C., 2021, In: Molecular Pharmaceutics. 18, 3, p. 1264-1276Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Predictive identification of co-formers in co-amorphous systems
Chambers, L. I., Grohganz, Holger, Palmelund, H., Löbmann, Korbinian, Rades, Thomas, Musa, O. M. & Steed, J. W., 2021, In: European Journal of Pharmaceutical Sciences. 157, 9 p., 105636.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Probabilistic modeling of an injectable aqueous crystalline suspension using influence networks
Sekulovic, A., Petit, M., Verrijk, R., Rades, Thomas & Rantanen, Jukka, 2021, In: International Journal of Pharmaceutics. 596, 11 p., 120283.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Screening of novel excipients for freeze-dried protein formulations
Holm, T. P., Meng-Lund, H., Rantanen, Jukka, Jørgensen, Lene & Grohganz, Holger, 2021, In: European Journal of Pharmaceutics and Biopharmaceutics. 160, p. 55-64 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Simultaneous automated image analysis and Raman spectroscopy of powders at an individual particle level
Sekulovic, A., Verrijk, R., Rades, Thomas, Grabarek, A., Jiskoot, W., Hawe, A. & Rantanen, Jukka, 2021, In: Journal of Pharmaceutical and Biomedical Analysis. 193, 8 p., 113744.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Studying the impact of the temperature and sorbed water during microwave-induced In Situ amorphization: A case study of celecoxib and polyvinylpyrrolidone
Hempel, N. J., Knopp, Matthias Manne, Löbmann, Korbinian & Berthelsen, R., 2021, In: Pharmaceutics. 13, 6, 13 p., 886.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Influence of Drug-Polymer Solubility on Laser-Induced In Situ Drug Amorphization Using Photothermal Plasmonic Nanoparticles
Hempel, N., Merkl, P., Knopp, Matthias Manne, Berthelsen, R., Teleki, A., Sotiriou, G. A. & Löbmann, Korbinian, 2021, In: Pharmaceutics. 13, 6, 12 p., 917.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Influence of Temperature and Viscosity of Polyethylene Glycol on the Rate of Microwave-Induced In Situ Amorphization of Celecoxib
Hempel, N., Dao, T., Knopp, Matthias Manne, Berthelsen, R. & Löbmann, Korbinian, 2021, In: Molecules. 26, 1, 8 p., 110.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Use of Glycerol as an Enabling Excipient for Microwave-Induced In Situ Drug Amorphization
Hempel, N., Morsch, F., Knopp, Matthias Manne, Berthelsen, R. & Löbmann, Korbinian, 2021, In: Journal of Pharmaceutical Sciences. 110, 1, p. 155-163 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The influence of moisture on the storage stability of co-amorphous systems
Liu, J., Rades, Thomas & Grohganz, Holger, 2021, In: International Journal of Pharmaceutics. 605, 120802.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Utilizing Laser Activation of Photothermal Plasmonic Nanoparticles to Induce On-Demand Drug Amorphization inside a Tablet
Hempel, N. J., Merkl, P., Asad, S., Knopp, M. M., Berthelsen, R., Bergström, C. A. S., Teleki, A., Sotiriou, G. A. & Löbmann, Korbinian, 2021, In: Molecular Pharmaceutics. 18, 6, p. 2254–2262Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Vancomycin-Loaded Microneedle Arrays against Methicillin-Resistant Staphylococcus Aureus Skin Infections
Ziesmer, J., Tajpara, P., Hempel, N., Ehrstrom, M., Melican, K., Eidsmo, Liv & Sotiriou, G. A., 2021, In: Advanced Materials Technologies. 10 p., 2001307.Research output: Contribution to journal › Journal article › Research › peer-review
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Self-microemulsifying drug delivery system and nanoemulsion for enhancing aqueous miscibility of Alpinia galanga oil
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Influence of Solvent Composition on the Performance of Spray-Dried Co-Amorphous Formulations
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Induction of Cytotoxic T-Lymphocyte Responses Upon Subcutaneous Administration of a Subunit Vaccine Adjuvanted With an Emulsion Containing the Toll-Like Receptor 3 Ligand Poly(I:C)
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Indomethacin-omeprazole as therapeutic hybrids? Salt and co-amorphous systems enhancing physicochemical and pharmacological properties
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The interplay between trehalose and dextran as spray drying precursors for cationic liposomes
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Use of solid thermolytic salts to facilitate microwave-induced in situ amorphization
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