Solid State Pharmaceutics

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  1. 2024
  2. Published

    Acheta domesticus: A Natural Source of Anti-Skin-Aging Ingredients for Cosmetic Applications

    Yeerong, K., Chantawannakul, P., Anuchapreeda, S., Rades, Thomas, Mullertz, Anette & Chaiyana, W., 2024, In: Pharmaceuticals. 17, 3, 20 p., 346.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Analysis of stabilization mechanisms in β-lactoglobulin-based amorphous solid dispersions by experimental and computational approaches

    Zhuo, Xuezhi, Foderà, Vito, Larsson, P., Schaal, Z., Bergström, C. A. S., Löbmann, Korbinian & Kabedev, A., 2024, In: European Journal of Pharmaceutical Sciences. 192, 13 p., 106639.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Coaxial electrospinning of polycaprolactone: A design of experiments approach

    Gürtler, Anna-Lena, Linseisen, I., Grohganz, Holger & Heinz, Andrea, 2024, In: European Polymer Journal. 208, 11 p., 112886.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Comparison of the liquisolid technique and co-milling for loading of a poorly soluble drug in inorganic porous excipients

    Ogadah, C. U., Mrštná, K., Matysová, L., Mullertz, Anette , Rades, Thomas, Niederquell, A., Šklubalová, Z. & Vraníková, B., 2024, In: International Journal of Pharmaceutics. 650, 10 p., 123702.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Destabilization of Indomethacin-Paracetamol Co-Amorphous Systems by Mechanical Stress

    Di, Rong, Grohganz, Holger & Rades, Thomas, 2024, In: Pharmaceutics. 16, 15 p., 67.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Effect of Drug Loading in Mesoporous Silica on Amorphous Stability and Performance

    Bavnhøj, C. G., Knopp, Matthias Manne & Löbmann, Korbinian, 2024, In: Pharmaceutics. 16, 2, 11 p., 163.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Exploring the effect of protein secondary structure on the solid state and physical stability of protein-based amorphous solid dispersions

    Zhuo, Xuezhi, Ochner, J., Leng, D., Foderà, Vito & Löbmann, Korbinian, 2024, In: European Journal of Pharmaceutics and Biopharmaceutics. 198, 8 p., 114274.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Indomethacin-omeprazole as therapeutic hybrids? Salt and co-amorphous systems enhancing physicochemical and pharmacological properties

    Carneiro Soares Do Nascimento, A L, Batista Martins, Inês Catarina, Spósito, L., Morais-Silva, G., Duarte, J. L., Rades, Thomas & Chorilli, M., 2024, In: International Journal of Pharmaceutics. 653, 11 p., 123857.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Influence of preparation method and choice of phospholipid on co-amorphization, physical stability, and dissolution behavior of equimolar indomethacin-phospholipid systems: A case study

    Khorami, Keyoomars, Mullertz, Anette & Rades, Thomas, 2024, In: Journal of Drug Delivery Science and Technology. 93, 8 p., 105433.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Influence of water and trehalose on α- and β-relaxation of freeze-dried lysozyme formulations

    Vallaster, B., Engelsing, F. & Grohganz, Holger, 2024, In: European Journal of Pharmaceutics and Biopharmaceutics. 194, p. 1-8

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Investigating the influence of protein secondary structure on the dissolution behavior of β-lactoglobulin-based amorphous solid dispersions

    Zhuo, Xuezhi, Tozzetti, M., Arnous, A., Leng, D., Foderà, Vito & Löbmann, Korbinian, 2024, In: International Journal of Pharmaceutics. 653, 8 p., 123887.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Lipid nanoparticles for local delivery of mRNA to the respiratory tract: Effect of PEG-lipid content and administration route

    Ongun, Melike, Lokras, Abhijeet, Baghel, Saahil Sandeep, Shi, Zhenning, Schmidt, S. T., Franzyk, Henrik, Rades, Thomas, Sebastiani, Federica, Thakur, A. & Foged, Camilla, 2024, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 198, 10 p., 114266.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Molecular interactions of hydrated co-amorphous systems of prilocaine and lidocaine

    Xu, X., Rades, Thomas & Grohganz, Holger, 2024, In: International Journal of Pharmaceutics. 651, 7 p., 123807.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    The interplay between trehalose and dextran as spray drying precursors for cationic liposomes

    Lutta, A., Knopp, Matthias Manne, Tollemeto, M., Pedersen, Gabriel Kristian, Schmidt, S. T., Grohganz, Holger & Hagner Nielsen, L., 2024, In: International Journal of Pharmaceutics. 652, 10 p., 123798.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Use of solid thermolytic salts to facilitate microwave-induced in situ amorphization

    Qiang, W., Zhang, M., Löbmann, Korbinian, McCoy, C. P., Andrews, G. P. & Zhao, M., 2024, In: International Journal of Pharmaceutics. 651, 11 p., 123791.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. 2023
  18. Published

    In vitro-in vivo relationship for amorphous solid dispersions using a double membrane dissolution-permeation setup

    Jørgensen, J. R., Mohr, W., Rischer, M., Sauer, A., Mistry, S., Rades, Thomas & Mullertz, Anette , 2023, In: European Journal of Pharmaceutics and Biopharmaceutics. 188, p. 26-32

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    A Comparative Study between A Protein Based Amorphous Formulation and Other Dissolution Rate Enhancing Approaches: A Case Study with Rifaximin

    Zhuo, Xuezhi, Margrethe Brekstad Kjellin, M., Schaal, Z., Zhang, T., Löbmann, Korbinian & Leng, D., 2023, In: Pharmaceutics. 15, 1, 10 p., 126.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Amorphization of different furosemide polymorphic forms during ball milling: Tracking solid-to-solid phase transformations

    Wang, M., Gong, J., Rades, Thomas & Batista Martins, Inês Catarina, 2023, In: International Journal of Pharmaceutics. 648, 9 p., 123573.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Assessing acute colitis induced by dextran sulfate sodium in rats and its impact on gastrointestinal fluids

    Klitgaard, Mette, Kristensen, M. N., Venkatasubramanian, R., Guerra, Priscila Regina, Jacobsen, Jette, Berthelsen, R., Rades, Thomas & Mullertz, Anette , 2023, In: Drug Delivery and Translational Research. 13, p. 1484–1499

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Co-amorphous systems consisting of indomethacin and the chiral co-former tryptophan: Solid-state properties and molecular mobilities

    Holzapfel, K., Rades, Thomas & Leopold, C. S., 2023, In: International Journal of Pharmaceutics. 636, 12 p., 122840.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Compaction Behavior of Co-Amorphous Systems

    Sørensen, C. M., Rantanen, Jukka & Grohganz, Holger, 2023, In: Pharmaceutics. 15, 3, 12 p., 858.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Considerations on the Kinetic Processes in the Preparation of Ternary Co-Amorphous Systems by Milling

    Wang, Y., Rades, Thomas & Grohganz, Holger, 2023, In: Pharmaceutics. 15, 1, 14 p., 172.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Design of experiments approach on the compaction properties of co-amorphous tablets

    Engelsing, F., Buchart, L. & Grohganz, Holger, 2023, In: Pharmaceutical Development and Technology. 28, 9, p. 907-914

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Editorial: In honor of Professor Ian Tucker

    Das, S., Rades, Thomas & McDowell, A., 2023, In: International Journal of Pharmaceutics. 638, 2 p., 122762.

    Research output: Contribution to journal › Editorial › Research › peer-review

  27. Published

    Electrospun fibers for the treatment of skin diseases

    Gürtler, Anna-Lena, Rades, Thomas & Heinz, Andrea, 2023, In: Journal of controlled release : official journal of the Controlled Release Society. 363, p. 621-640

    Research output: Contribution to journal › Review › Research › peer-review

  28. Published

    Elucidating the nanostructure of small interfering RNA-loaded lipidoid-polymer hybrid nanoparticles

    Aljabbari, Anas Samir Mohammad, Lokras, Abhijeet, Kirkensgaard, Jacob Judas Kain, Rades, Thomas, Franzyk, Henrik, Thakur, A., Zhang, Y. & Foged, Camilla, 2023, In: Journal of Colloid and Interface Science. 633, p. 907-922

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Enhancing tabletability of high-dose tablets by tailoring properties of spray-dried insulin particles

    Pedersen, M. D., Megarry, A., Naelapää, K., Rades, Thomas & Pessi, J., 2023, In: International Journal of Pharmaceutics. 631, 8 p., 122526.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Exploring the Solid-State Landscape of Carbamazepine during Dehydration: A Low Frequency Raman Spectroscopy Perspective

    Remoto, P. I. I. I. J. G., Bērziņš, Kārlis, Fraser-Miller, S. J., Korter, T. M., Rades, Thomas, Rantanen, Jukka & Gordon, K. C., 2023, In: Pharmaceutics. 15, 5, 15 p., 1526.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Functionalized calcium carbonate (FCC) as a novel carrier to solidify supersaturated self-nanoemulsifying drug delivery systems (super-SNEDDS)

    Merchant, J., Mullertz, Anette , Rades, Thomas & Bannow, J., 2023, In: European Journal of Pharmaceutics and Biopharmaceutics. 193, p. 198-207

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Influence of Polyvinylpyrrolidone Molecular Weight and Concentration on the Precipitation Inhibition of Supersaturated Solutions of Poorly Soluble Drugs

    Odeh, A. B., El-Sayed, B., Knopp, Matthias Manne, Rades, Thomas & Blaabjerg, L. I., 2023, In: Pharmaceutics. 15, 6, 17 p., 1601.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Interaction of liposomes with bile salts investigated by asymmetric flow field-flow fractionation (AF4): A novel approach for stability assessment of oral drug carriers

    Bohsen, M. S., Tychsen, S. T., Kadhim, A. A. H., Grohganz, Holger, Treusch, A. H. & Brandl, M., 2023, In: European Journal of Pharmaceutical Sciences. 182, 10 p., 106384.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Mechanisms of Drug Solubility Enhancement Induced by β-Lactoglobulin-Based Amorphous Solid Dispersions

    Zhuo, Xuezhi, Sener, Z., Kabedev, A., Zhao, M., Arnous, A., Leng, D., Foderà, Vito & Löbmann, Korbinian, 2023, In: Molecular Pharmaceutics. 20, 10, p. 5206–5213

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Preparation of Co-Amorphous Levofloxacin Systems for Pulmonary Application

    Gabelmann, A., Lehr, C. M. & Grohganz, Holger, 2023, In: Pharmaceutics. 15, 6, 15 p., 1574.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Recent Advances in Co-Former Screening and Formation Prediction of Multicomponent Solid Forms of Low Molecular Weight Drugs

    Deng, Y., Liu, S., Jiang, Y., Batista Martins, Inês Catarina & Rades, Thomas, 2023, In: Pharmaceutics. 15, 9, 33 p., 2174.

    Research output: Contribution to journal › Review › Research › peer-review

  37. Published

    Solid-state analysis for pharmaceuticals: Pathways to feasible and meaningful analysis

    Rantanen, Jukka, Rades, Thomas & Strachan, C., 2023, In: Journal of Pharmaceutical and Biomedical Analysis. 236, 7 p., 115649.

    Research output: Contribution to journal › Review › Research › peer-review

  38. Published

    Stability and intrinsic dissolution of vacuum compression molded amorphous solid dispersions of efavirenz

    Jørgensen, J. R., Mohr, W., Rischer, M., Sauer, A., Mistry, S., Mullertz, Anette & Rades, Thomas, 2023, In: International Journal of Pharmaceutics. 632, 8 p., 122564.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    The Influence of Gastrointestinal Biomolecules on Solid-State Transformations in Pharmaceutical Particulates

    Aljabbari, Anas Samir Mohammad, Kihara, Shinji, Rades, Thomas, Boyd, Ben & Bērziņš, Kārlis, 2023, In: Molecular Pharmaceutics. 20, 8, p. 4297-4306

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    The biomolecular gastrointestinal corona in oral drug delivery

    Aljabbari, Anas Samir Mohammad, Kihara, Shinji, Rades, Thomas & Boyd, Ben, 2023, In: Journal of controlled release : official journal of the Controlled Release Society. 363, p. 536-549

    Research output: Contribution to journal › Review › Research › peer-review

  41. Published

    The effects of surfactants on the performance of polymer-based microwave-induced in situ amorphization

    Qiang, W., Löbmann, Korbinian, McCoy, C. P., Andrews, G. P. & Zhao, M., 2023, In: International Journal of Pharmaceutics. 630, 17 p., 122426.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Thermal investigation on hydrated co-amorphous systems of nicotinamide and prilocaine

    Xu, X., Rades, Thomas & Grohganz, Holger, 2023, In: European Journal of Pharmaceutics and Biopharmaceutics. 186, p. 1-6

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Unveiling polyamorphism and polyamorphic interconversions in pharmaceuticals: the peculiar case of hydrochlorothiazide

    Batista Martins, Inês Catarina, Larsen, A. S., Madsen, Anders Østergaard, Aalling-Frederiksen, Olivia, Correia, A., Jensen, Kirsten Marie Ørnsbjerg, Jeppesen, H. S. & Rades, Thomas, 2023, In: Chemical Science. 14, 41, p. 11447-11455 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Wet granulation of co-amorphous indomethacin systems

    Schütz, D., Timmerhaus, A. & Grohganz, Holger, 2023, In: International Journal of Pharmaceutics. 644, 9 p., 123318.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. 2022
  46. Published

    (Co-)amorphization of enantiomers – Investigation of the amorphization process, the physical stability and the dissolution behavior

    Holzapfel, K., Liu, J., Rades, Thomas & Leopold, C. S., 2022, In: International Journal of Pharmaceutics. 616, 9 p., 121552.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    A new method to determine drug-polymer solubility through enthalpy of melting and mixing

    Meiland, Peter, Larsen, B. S., Knopp, Matthias Manne, Tho, I. & Rades, Thomas, 2022, In: International Journal of Pharmaceutics. 629, 9 p., 122391.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Additive manufacturing in respiratory sciences – Current applications and future prospects

    Bock, S., Rades, Thomas, Rantanen, Jukka & Scherließ, R., 2022, In: Advanced Drug Delivery Reviews. 186, 14 p., 114341.

    Research output: Contribution to journal › Review › Research › peer-review

  49. Published

    Combining lipid based drug delivery and amorphous solid dispersions for improved oral drug absorption of a poorly water-soluble drug

    Nora, G., Venkatasubramanian, R., Strindberg, S., Siqueira-Jørgensen, S. D., Pagano, L., Romanski, F. S., Swarnakar, N. K., Rades, Thomas & Mullertz, Anette , 2022, In: Journal of Controlled Release. 349, p. 206-212

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Development of a Microgram Scale Video-Microscopic Method to Investigate Dissolution Behavior of Poorly Water-Soluble Drugs

    Senniksen, M. B., Christfort, J. F., Marabini, R., Spillum, E., Matthews, W., Da Vià, L., Plum, J., Rades, Thomas & Mullertz, Anette , 2022, In: AAPS PharmSciTech. 23, 6, 173.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    Development of a multiparticulate drug delivery system for in situ amorphisation

    Holm, T. P., Kokott, M., Knopp, Matthias Manne, Boyd, Ben, Berthelsen, R., Quodbach, J. & Löbmann, Korbinian, 2022, In: European Journal of Pharmaceutics and Biopharmaceutics. 180, p. 170-180

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Effects of polymer addition on the non-strongly interacting binary co-amorphous system carvedilol-tryptophan

    Wang, Y., Grohganz, Holger & Rades, Thomas, 2022, In: International Journal of Pharmaceutics. 617, 9 p., 121625.

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    Elucidating Pathway and Anesthetic Mechanism of Action of Clove Oil Nanoformulations in Fish

    Kheawfu, K., Pikulkaew, S., Wellendorph, Petrine, Jørgensen, Louise von Gersdorff, Rades, Thomas, Mullertz, Anette & Okonogi, S., 2022, In: Pharmaceutics. 14, 5, 13 p., 919.

    Research output: Contribution to journal › Journal article › Research › peer-review

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