Solid State Pharmaceutics

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  1. 2024
  2. Published

    Acheta domesticus: A Natural Source of Anti-Skin-Aging Ingredients for Cosmetic Applications

    Yeerong, K., Chantawannakul, P., Anuchapreeda, S., Rades, Thomas, Mullertz, Anette & Chaiyana, W., 2024, In: Pharmaceuticals. 17, 3, 20 p., 346.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Analysis of stabilization mechanisms in β-lactoglobulin-based amorphous solid dispersions by experimental and computational approaches

    Zhuo, Xuezhi, Foderà, Vito, Larsson, P., Schaal, Z., Bergström, C. A. S., Löbmann, Korbinian & Kabedev, A., 2024, In: European Journal of Pharmaceutical Sciences. 192, 13 p., 106639.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Coaxial electrospinning of polycaprolactone: A design of experiments approach

    Gürtler, Anna-Lena, Linseisen, I., Grohganz, Holger & Heinz, Andrea, 2024, In: European Polymer Journal. 208, 11 p., 112886.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Comparison of the liquisolid technique and co-milling for loading of a poorly soluble drug in inorganic porous excipients

    Ogadah, C. U., Mrštná, K., Matysová, L., Mullertz, Anette , Rades, Thomas, Niederquell, A., Šklubalová, Z. & Vraníková, B., 2024, In: International Journal of Pharmaceutics. 650, 10 p., 123702.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Destabilization of Indomethacin-Paracetamol Co-Amorphous Systems by Mechanical Stress

    Di, Rong, Grohganz, Holger & Rades, Thomas, 2024, In: Pharmaceutics. 16, 15 p., 67.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Effect of Drug Loading in Mesoporous Silica on Amorphous Stability and Performance

    Bavnhøj, C. G., Knopp, Matthias Manne & Löbmann, Korbinian, 2024, In: Pharmaceutics. 16, 2, 11 p., 163.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Exploring the effect of protein secondary structure on the solid state and physical stability of protein-based amorphous solid dispersions

    Zhuo, Xuezhi, Ochner, J., Leng, D., Foderà, Vito & Löbmann, Korbinian, 2024, In: European Journal of Pharmaceutics and Biopharmaceutics. 198, 8 p., 114274.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Indomethacin-omeprazole as therapeutic hybrids? Salt and co-amorphous systems enhancing physicochemical and pharmacological properties

    Carneiro Soares Do Nascimento, A L, Batista Martins, Inês Catarina, Spósito, L., Morais-Silva, G., Duarte, J. L., Rades, Thomas & Chorilli, M., 2024, In: International Journal of Pharmaceutics. 653, 11 p., 123857.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Influence of preparation method and choice of phospholipid on co-amorphization, physical stability, and dissolution behavior of equimolar indomethacin-phospholipid systems: A case study

    Khorami, Keyoomars, Mullertz, Anette & Rades, Thomas, 2024, In: Journal of Drug Delivery Science and Technology. 93, 8 p., 105433.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Influence of water and trehalose on α- and β-relaxation of freeze-dried lysozyme formulations

    Vallaster, B., Engelsing, F. & Grohganz, Holger, 2024, In: European Journal of Pharmaceutics and Biopharmaceutics. 194, p. 1-8

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Investigating the influence of protein secondary structure on the dissolution behavior of β-lactoglobulin-based amorphous solid dispersions

    Zhuo, Xuezhi, Tozzetti, M., Arnous, A., Leng, D., Foderà, Vito & Löbmann, Korbinian, 2024, In: International Journal of Pharmaceutics. 653, 8 p., 123887.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Lipid nanoparticles for local delivery of mRNA to the respiratory tract: Effect of PEG-lipid content and administration route

    Ongun, Melike, Lokras, Abhijeet, Baghel, Saahil Sandeep, Shi, Zhenning, Schmidt, S. T., Franzyk, Henrik, Rades, Thomas, Sebastiani, Federica, Thakur, A. & Foged, Camilla, 2024, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 198, 10 p., 114266.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Molecular interactions of hydrated co-amorphous systems of prilocaine and lidocaine

    Xu, X., Rades, Thomas & Grohganz, Holger, 2024, In: International Journal of Pharmaceutics. 651, 7 p., 123807.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    The interplay between trehalose and dextran as spray drying precursors for cationic liposomes

    Lutta, A., Knopp, Matthias Manne, Tollemeto, M., Pedersen, Gabriel Kristian, Schmidt, S. T., Grohganz, Holger & Hagner Nielsen, L., 2024, In: International Journal of Pharmaceutics. 652, 10 p., 123798.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Use of solid thermolytic salts to facilitate microwave-induced in situ amorphization

    Qiang, W., Zhang, M., Löbmann, Korbinian, McCoy, C. P., Andrews, G. P. & Zhao, M., 2024, In: International Journal of Pharmaceutics. 651, 11 p., 123791.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. 2023
  18. Published

    In vitro-in vivo relationship for amorphous solid dispersions using a double membrane dissolution-permeation setup

    Jørgensen, J. R., Mohr, W., Rischer, M., Sauer, A., Mistry, S., Rades, Thomas & Mullertz, Anette , 2023, In: European Journal of Pharmaceutics and Biopharmaceutics. 188, p. 26-32

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    A Comparative Study between A Protein Based Amorphous Formulation and Other Dissolution Rate Enhancing Approaches: A Case Study with Rifaximin

    Zhuo, Xuezhi, Margrethe Brekstad Kjellin, M., Schaal, Z., Zhang, T., Löbmann, Korbinian & Leng, D., 2023, In: Pharmaceutics. 15, 1, 10 p., 126.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Amorphization of different furosemide polymorphic forms during ball milling: Tracking solid-to-solid phase transformations

    Wang, M., Gong, J., Rades, Thomas & Batista Martins, Inês Catarina, 2023, In: International Journal of Pharmaceutics. 648, 9 p., 123573.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Assessing acute colitis induced by dextran sulfate sodium in rats and its impact on gastrointestinal fluids

    Klitgaard, Mette, Kristensen, M. N., Venkatasubramanian, R., Guerra, Priscila Regina, Jacobsen, Jette, Berthelsen, R., Rades, Thomas & Mullertz, Anette , 2023, In: Drug Delivery and Translational Research. 13, p. 1484–1499

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Co-amorphous systems consisting of indomethacin and the chiral co-former tryptophan: Solid-state properties and molecular mobilities

    Holzapfel, K., Rades, Thomas & Leopold, C. S., 2023, In: International Journal of Pharmaceutics. 636, 12 p., 122840.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Compaction Behavior of Co-Amorphous Systems

    Sørensen, C. M., Rantanen, Jukka & Grohganz, Holger, 2023, In: Pharmaceutics. 15, 3, 12 p., 858.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Considerations on the Kinetic Processes in the Preparation of Ternary Co-Amorphous Systems by Milling

    Wang, Y., Rades, Thomas & Grohganz, Holger, 2023, In: Pharmaceutics. 15, 1, 14 p., 172.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Design of experiments approach on the compaction properties of co-amorphous tablets

    Engelsing, F., Buchart, L. & Grohganz, Holger, 2023, In: Pharmaceutical Development and Technology. 28, 9, p. 907-914

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Editorial: In honor of Professor Ian Tucker

    Das, S., Rades, Thomas & McDowell, A., 2023, In: International Journal of Pharmaceutics. 638, 2 p., 122762.

    Research output: Contribution to journal › Editorial › Research › peer-review

  27. Published

    Electrospun fibers for the treatment of skin diseases

    Gürtler, Anna-Lena, Rades, Thomas & Heinz, Andrea, 2023, In: Journal of controlled release : official journal of the Controlled Release Society. 363, p. 621-640

    Research output: Contribution to journal › Review › Research › peer-review

  28. Published

    Elucidating the nanostructure of small interfering RNA-loaded lipidoid-polymer hybrid nanoparticles

    Aljabbari, Anas Samir Mohammad, Lokras, Abhijeet, Kirkensgaard, Jacob Judas Kain, Rades, Thomas, Franzyk, Henrik, Thakur, A., Zhang, Y. & Foged, Camilla, 2023, In: Journal of Colloid and Interface Science. 633, p. 907-922

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Enhancing tabletability of high-dose tablets by tailoring properties of spray-dried insulin particles

    Pedersen, M. D., Megarry, A., Naelapää, K., Rades, Thomas & Pessi, J., 2023, In: International Journal of Pharmaceutics. 631, 8 p., 122526.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Exploring the Solid-State Landscape of Carbamazepine during Dehydration: A Low Frequency Raman Spectroscopy Perspective

    Remoto, P. I. I. I. J. G., Bērziņš, Kārlis, Fraser-Miller, S. J., Korter, T. M., Rades, Thomas, Rantanen, Jukka & Gordon, K. C., 2023, In: Pharmaceutics. 15, 5, 15 p., 1526.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Functionalized calcium carbonate (FCC) as a novel carrier to solidify supersaturated self-nanoemulsifying drug delivery systems (super-SNEDDS)

    Merchant, J., Mullertz, Anette , Rades, Thomas & Bannow, J., 2023, In: European Journal of Pharmaceutics and Biopharmaceutics. 193, p. 198-207

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Influence of Polyvinylpyrrolidone Molecular Weight and Concentration on the Precipitation Inhibition of Supersaturated Solutions of Poorly Soluble Drugs

    Odeh, A. B., El-Sayed, B., Knopp, Matthias Manne, Rades, Thomas & Blaabjerg, L. I., 2023, In: Pharmaceutics. 15, 6, 17 p., 1601.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Interaction of liposomes with bile salts investigated by asymmetric flow field-flow fractionation (AF4): A novel approach for stability assessment of oral drug carriers

    Bohsen, M. S., Tychsen, S. T., Kadhim, A. A. H., Grohganz, Holger, Treusch, A. H. & Brandl, M., 2023, In: European Journal of Pharmaceutical Sciences. 182, 10 p., 106384.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Mechanisms of Drug Solubility Enhancement Induced by β-Lactoglobulin-Based Amorphous Solid Dispersions

    Zhuo, Xuezhi, Sener, Z., Kabedev, A., Zhao, M., Arnous, A., Leng, D., Foderà, Vito & Löbmann, Korbinian, 2023, In: Molecular Pharmaceutics. 20, 10, p. 5206–5213

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Preparation of Co-Amorphous Levofloxacin Systems for Pulmonary Application

    Gabelmann, A., Lehr, C. M. & Grohganz, Holger, 2023, In: Pharmaceutics. 15, 6, 15 p., 1574.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Recent Advances in Co-Former Screening and Formation Prediction of Multicomponent Solid Forms of Low Molecular Weight Drugs

    Deng, Y., Liu, S., Jiang, Y., Batista Martins, Inês Catarina & Rades, Thomas, 2023, In: Pharmaceutics. 15, 9, 33 p., 2174.

    Research output: Contribution to journal › Review › Research › peer-review

  37. Published

    Solid-state analysis for pharmaceuticals: Pathways to feasible and meaningful analysis

    Rantanen, Jukka, Rades, Thomas & Strachan, C., 2023, In: Journal of Pharmaceutical and Biomedical Analysis. 236, 7 p., 115649.

    Research output: Contribution to journal › Review › Research › peer-review

  38. Published

    Stability and intrinsic dissolution of vacuum compression molded amorphous solid dispersions of efavirenz

    Jørgensen, J. R., Mohr, W., Rischer, M., Sauer, A., Mistry, S., Mullertz, Anette & Rades, Thomas, 2023, In: International Journal of Pharmaceutics. 632, 8 p., 122564.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    The Influence of Gastrointestinal Biomolecules on Solid-State Transformations in Pharmaceutical Particulates

    Aljabbari, Anas Samir Mohammad, Kihara, Shinji, Rades, Thomas, Boyd, Ben & Bērziņš, Kārlis, 2023, In: Molecular Pharmaceutics. 20, 8, p. 4297-4306

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    The biomolecular gastrointestinal corona in oral drug delivery

    Aljabbari, Anas Samir Mohammad, Kihara, Shinji, Rades, Thomas & Boyd, Ben, 2023, In: Journal of controlled release : official journal of the Controlled Release Society. 363, p. 536-549

    Research output: Contribution to journal › Review › Research › peer-review

  41. Published

    The effects of surfactants on the performance of polymer-based microwave-induced in situ amorphization

    Qiang, W., Löbmann, Korbinian, McCoy, C. P., Andrews, G. P. & Zhao, M., 2023, In: International Journal of Pharmaceutics. 630, 17 p., 122426.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Thermal investigation on hydrated co-amorphous systems of nicotinamide and prilocaine

    Xu, X., Rades, Thomas & Grohganz, Holger, 2023, In: European Journal of Pharmaceutics and Biopharmaceutics. 186, p. 1-6

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Unveiling polyamorphism and polyamorphic interconversions in pharmaceuticals: the peculiar case of hydrochlorothiazide

    Batista Martins, Inês Catarina, Larsen, A. S., Madsen, Anders Østergaard, Aalling-Frederiksen, Olivia, Correia, A., Jensen, Kirsten Marie Ørnsbjerg, Jeppesen, H. S. & Rades, Thomas, 2023, In: Chemical Science. 14, 41, p. 11447-11455 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Wet granulation of co-amorphous indomethacin systems

    Schütz, D., Timmerhaus, A. & Grohganz, Holger, 2023, In: International Journal of Pharmaceutics. 644, 9 p., 123318.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. 2022
  46. Published

    (Co-)amorphization of enantiomers – Investigation of the amorphization process, the physical stability and the dissolution behavior

    Holzapfel, K., Liu, J., Rades, Thomas & Leopold, C. S., 2022, In: International Journal of Pharmaceutics. 616, 9 p., 121552.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    A new method to determine drug-polymer solubility through enthalpy of melting and mixing

    Meiland, Peter, Larsen, B. S., Knopp, Matthias Manne, Tho, I. & Rades, Thomas, 2022, In: International Journal of Pharmaceutics. 629, 9 p., 122391.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Additive manufacturing in respiratory sciences – Current applications and future prospects

    Bock, S., Rades, Thomas, Rantanen, Jukka & Scherließ, R., 2022, In: Advanced Drug Delivery Reviews. 186, 14 p., 114341.

    Research output: Contribution to journal › Review › Research › peer-review

  49. Published

    Combining lipid based drug delivery and amorphous solid dispersions for improved oral drug absorption of a poorly water-soluble drug

    Nora, G., Venkatasubramanian, R., Strindberg, S., Siqueira-Jørgensen, S. D., Pagano, L., Romanski, F. S., Swarnakar, N. K., Rades, Thomas & Mullertz, Anette , 2022, In: Journal of Controlled Release. 349, p. 206-212

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Development of a Microgram Scale Video-Microscopic Method to Investigate Dissolution Behavior of Poorly Water-Soluble Drugs

    Senniksen, M. B., Christfort, J. F., Marabini, R., Spillum, E., Matthews, W., Da Vià, L., Plum, J., Rades, Thomas & Mullertz, Anette , 2022, In: AAPS PharmSciTech. 23, 6, 173.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    Development of a multiparticulate drug delivery system for in situ amorphisation

    Holm, T. P., Kokott, M., Knopp, Matthias Manne, Boyd, Ben, Berthelsen, R., Quodbach, J. & Löbmann, Korbinian, 2022, In: European Journal of Pharmaceutics and Biopharmaceutics. 180, p. 170-180

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Effects of polymer addition on the non-strongly interacting binary co-amorphous system carvedilol-tryptophan

    Wang, Y., Grohganz, Holger & Rades, Thomas, 2022, In: International Journal of Pharmaceutics. 617, 9 p., 121625.

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    Elucidating Pathway and Anesthetic Mechanism of Action of Clove Oil Nanoformulations in Fish

    Kheawfu, K., Pikulkaew, S., Wellendorph, Petrine, Jørgensen, Louise von Gersdorff, Rades, Thomas, Mullertz, Anette & Okonogi, S., 2022, In: Pharmaceutics. 14, 5, 13 p., 919.

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. Published

    Elucidating the Dehydration Mechanism of Nitrofurantoin Monohydrate II Using Low-Frequency Raman Spectroscopy

    Remoto, P. J. G., Bērziņš, Kārlis, Fraser-Miller, S. J., Korter, T. M., Rades, Thomas, Rantanen, Jukka & Gordon, K. C., 2022, In: Crystal Growth and Design. 22, 4, p. 2733-2741

    Research output: Contribution to journal › Journal article › Research › peer-review

  55. Published

    Hyperthermia-Induced In Situ Drug Amorphization by Superparamagnetic Nanoparticles in Oral Dosage Forms

    Ansari, S. R., Hempel, N. J., Asad, S., Svedlindh, P., Bergström, C. A. S., Löbmann, Korbinian & Teleki, A., 2022, In: ACS Applied Materials and Interfaces. 14, 19, p. 21978–21988

    Research output: Contribution to journal › Journal article › Research › peer-review

  56. Published

    Impact of Molecular Surface Diffusion on the Physical Stability of Co-Amorphous Systems

    Liu, J., Hwu, E., Bannow, J., Grohganz, Holger & Rades, Thomas, 2022, In: Molecular Pharmaceutics. 19, 4, p. 1183-1190

    Research output: Contribution to journal › Journal article › Research › peer-review

  57. Published

    Impact of oral gavage technique of drug-containing microcontainers on the gastrointestinal transit and absorption in rats

    Kristensen, M. N., Rades, Thomas, Boisen, A. & Mullertz, Anette , 2022, In: International Journal of Pharmaceutics. 618, 121630.

    Research output: Contribution to journal › Journal article › Research › peer-review

  58. Published

    In Situ Transformation of Electrospun Nanofibers into Nanofiber-Reinforced Hydrogels

    Martin, A., Nyman, J. N., Reinholdt, R., Cai, J., Gürtler, Anna-Lena, van der Plas, Mariena J.A., Malmsten, Martin, Rades, Thomas & Heinz, Andrea, 2022, In: Nanomaterials. 12, 14, 2437.

    Research output: Contribution to journal › Journal article › Research › peer-review

  59. Published

    Influence of Water on Amorphous Lidocaine

    Xu, X., Grohganz, Holger & Rades, Thomas, 2022, In: Molecular Pharmaceutics. 19, 9, p. 3199–3205

    Research output: Contribution to journal › Journal article › Research › peer-review

  60. Published

    Low-Frequency Raman Spectroscopy as an Avenue to Determine the Transition Temperature of β- and γ-Relaxation in Pharmaceutical Glasses

    Bērziņš, Kārlis, Fraser-Miller, S. J., Rades, Thomas & Gordon, K. C., 2022, In: Analytical Chemistry. 94, 23, p. 8241-8248

    Research output: Contribution to journal › Journal article › Research › peer-review

  61. Published

    Pharmaceutical Technology in Europe

    Siepmann, J., Basit, A. & Rades, Thomas, 2022, In: International Journal of Pharmaceutics. 613, 1 p., 121441.

    Research output: Contribution to journal › Editorial › Research

  62. Published

    Physico-chemical characterization of aspirated and simulated human gastric fluids to study their influence on the intrinsic dissolution rate of cinnarizine

    Pedersen, P. B., Berthelsen, R., Rades, Thomas, Jørgensen, S. A., Vilmann, Peter, Bar-Shalom, Daniel, Baldursdottir, S. & Mullertz, Anette , 2022, In: International Journal of Pharmaceutics. 622, 7 p., 121856.

    Research output: Contribution to journal › Journal article › Research › peer-review

  63. Published

    Simultaneous quantification of multiple RNA cargoes co-loaded into nanoparticle-based delivery systems

    Lokras, Abhijeet, Chakravarty, A., Rades, Thomas, Christensen, D., Franzyk, Henrik, Thakur, A. & Foged, Camilla, 2022, In: International Journal of Pharmaceutics. 626, 13 p., 122171.

    Research output: Contribution to journal › Journal article › Research › peer-review

  64. Published

    Solventless amorphization and pelletization using a high shear granulator. Part I; feasibility study using indomethacin

    Kondo, K. & Rades, Thomas, 2022, In: European Journal of Pharmaceutics and Biopharmaceutics. 181, p. 147-158

    Research output: Contribution to journal › Journal article › Research › peer-review

  65. Published

    Solventless amorphization and pelletization using a high shear granulator. Part II; Preparation of co-amorphous mixture-layered pellets using indomethacin and arginine

    Kondo, K. & Rades, Thomas, 2022, In: European Journal of Pharmaceutics and Biopharmaceutics. 181, p. 183-194

    Research output: Contribution to journal › Journal article › Research › peer-review

  66. Published

    Stabilizing Mechanisms of β-Lactoglobulin in Amorphous Solid Dispersions of Indomethacin

    Kabedev, A., Zhuo, Xuezhi, Leng, D., Foderà, Vito, Zhao, M., Larsson, P., Bergström, C. A. S. & Löbmann, Korbinian, 2022, In: Molecular Pharmaceutics. 19, 11, p. 3922–3933

    Research output: Contribution to journal › Journal article › Research › peer-review

  67. Published

    Supersaturated amorphous solid dispersions of celecoxib prepared in situ by microwave irradiation

    Holm, T. P., Knopp, Matthias Manne, Berthelsen, R. & Löbmann, Korbinian, 2022, In: International Journal of Pharmaceutics. 626, 8 p., 122115.

    Research output: Contribution to journal › Journal article › Research › peer-review

  68. Published

    The Binding of Alpinia galanga Oil and Its Nanoemulsion to Mammal GABA(A) Receptors Using Rat Cortical Membranes and an In Silico Modeling Platform

    Khumpirapang, N., Suknuntha, K., Wongrattanakamon, P., Jiranusornkul, S., Anuchapreeda, S., Wellendorph, Petrine, Mullertz, Anette , Rades, Thomas & Okonogi, S., 2022, In: Pharmaceutics. 14, 3, 15 p., 650.

    Research output: Contribution to journal › Journal article › Research › peer-review

  69. Published

    Topical niclosamide (ATx201) reduces Staphylococcus aureus colonization and increases Shannon diversity of the skin microbiome in atopic dermatitis patients in a randomized, double-blind, placebo-controlled Phase 2 trial

    Weiss, A., Delavenne, E., Matias, C., Lagler, H., Simon, D., Li, P., Hansen, J. U., Dos Santos, T. P., Jana, B., Priemel, P., Bangert, C., Bauer, M., Eberl, S., Nussbaumer-Pröll, A., Anne Österreicher, Z., Matzneller, P., Quint, T., Weber, M., Nielsen, H. M., Rades, T. & 17 others, Johansen, Helle Krogh, Westh, Henrik T., Kim, W., Mylonakis, E., Friis, C., Guardabassi, Luca, Pace, J., Lundberg, C. V., M'Zali, F., Butty, P., Sørensen, N., Nielsen, H. B., Toft-Kehler, R., Guttman-Yassky, E., Stingl, G., Zeitlinger, M. & Sommer, M., 2022, In: Clinical and Translational Medicine. 12, 5, e790.

    Research output: Contribution to journal › Journal article › Research › peer-review

  70. Published

    Zein-polycaprolactone core-shell nanofibers for wound healing

    Martin, A., Cai, J., Gürtler, Anna-Lena, van der Plas, Mariena J.A., Malmsten, Martin, Rades, Thomas & Heinz, Andrea, 2022, In: International Journal of Pharmaceutics. 621, 10 p., 121809.

    Research output: Contribution to journal › Journal article › Research › peer-review

  71. 2021
  72. Published

    The effect of the molecular weight of polyvinylpyrrolidone and the model drug on laser-induced in situ amorphization

    Hempel, N. J., Merkl, P., Knopp, Matthias Manne, Berthelsen, R., Teleki, A., Hansen, A. K., Sotiriou, G. A. & Löbmann, Korbinian, Jul 2021, In: Molecules. 26, 13, 13 p., 4035.

    Research output: Contribution to journal › Journal article › Research › peer-review

  73. Published

    A Multivariate Approach for the Determination of the Optimal Mixing Ratio of the Non-Strong Interacting Co-Amorphous System Carvedilol-Tryptophan

    Di, Rong, Liu, J., Grohganz, Holger & Rades, Thomas, 2021, In: Molecules. 26, 4, 8 p., 801.

    Research output: Contribution to journal › Journal article › Research › peer-review

  74. Published

    Co-Amorphous Drug Formulations in Numbers: Recent Advances in Co-Amorphous Drug Formulations with Focus on Co-Formability, Molar Ratio, Preparation Methods, Physical Stability, In Vitro and In Vivo Performance, and New Formulation Strategies

    Liu, J., Grohganz, Holger, Löbmann, Korbinian, Rades, Thomas & Hempel, N., 2021, In: Pharmaceutics. 13, 3, 43 p., 389.

    Research output: Contribution to journal › Review › Research

  75. Published

    Combined Effect of the Preparation Method and Compression on the Physical Stability and Dissolution Behavior of Melt-Quenched Amorphous Celecoxib

    Bērziņš, Kārlis, Fraser-Miller, S. J., Di, Rong, Liu, J., Peltonen, L., Strachan, C. J., Rades, Thomas & Gordon, K. C., 2021, In: Molecular Pharmaceutics. 18, 3, p. 1408-1418

    Research output: Contribution to journal › Journal article › Research › peer-review

  76. Published

    Comparison of co-former performance in co-amorphous formulations: Single amino acids, amino acid physical mixtures, amino acid salts and dipeptides as co-formers

    Wu, W., Grohganz, Holger, Rades, Thomas & Löbmann, Korbinian, 2021, In: European Journal of Pharmaceutical Sciences. 156, 8 p., 105582.

    Research output: Contribution to journal › Journal article › Research › peer-review

  77. Published

    Deliquescence Behavior of Deep Eutectic Solvents

    Palmelund, H., Rantanen, Jukka & Löbmann, Korbinian, 2021, In: Applied Sciences. 11, 9 p., 1601.

    Research output: Contribution to journal › Letter › Research › peer-review

  78. Published

    Design and optimization of self-nanoemulsifying drug delivery systems of clove oil for efficacy enhancement in fish anesthesia

    Kheawfu, Pikulkaew, Rades, Thomas, Mullertz, Anette , Jørgensen, Louise von Gersdorff & Okonogi, 2021, In: Journal of Drug Delivery Science and Technology. 61, 9 p., 102241.

    Research output: Contribution to journal › Journal article › Research › peer-review

  79. Published

    Design of a self-unfolding delivery concept for oral administration of macromolecules

    Jørgensen, J. R., Thamdrup, L. H. E., Kamguyan, K., Nielsen, L. H., Nielsen, Hanne Mørck, Boisen, A., Rades, Thomas & Mullertz, Anette , 2021, In: Journal of Controlled Release. 329, p. 948-954

    Research output: Contribution to journal › Journal article › Research › peer-review

  80. Published

    Development of Self-Nanoemulsifying Drug Delivery Systems Containing 4-Allylpyrocatechol for Treatment of Oral Infections Caused by Candida albicans

    Okonogi, S., Phumat, P., Khongkhunthian, S., Chaijareenont, P., Rades, Thomas & Mullertz, Anette , 2021, In: Pharmaceutics. 13, 2, 16 p., 167.

    Research output: Contribution to journal › Journal article › Research › peer-review

  81. Published

    Enabling formulations of aprepitant: in vitro and in vivo comparison of nanocrystalline, amorphous and deep eutectic solvent based formulations

    Palmelund, H., Eriksen, J. B., Bauer-Brandl, A., Rantanen, Jukka & Löbmann, Korbinian, 2021, In: International Journal of Pharmaceutics: X. 3, 100083.

    Research output: Contribution to journal › Journal article › Research › peer-review

  82. Published

    Exploring the Impact of Intestinal Fluid Components on the Solubility and Supersaturation of Danazol

    Madsen, C. M., Plum, J., Hens, B., Augustijns, P., Mullertz, Anette & Rades, Thomas, 2021, In: Journal of Pharmaceutical Sciences. 110, 6, p. 2479-2488 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  83. Published

    Formulation optimization, anesthetic activity, skin permeation, and transportation pathway of Alpinia galanga oil SNEDDS in zebrafish (Danio rerio)

    Khumpirapang, N., Jørgensen, Louise von Gersdorff, Mullertz, Anette , Rades, Thomas & Okonogi, S., 2021, In: European Journal of Pharmaceutics and Biopharmaceutics. 165, p. 193-202 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  84. Published

    Interactions of Cell-Penetrating Peptide-Modified Nanoparticles with Cells Evaluated Using Single Particle Tracking

    Streck, S., Bohr, S. S., Birch, D., Rades, Thomas, Hatzakis, Nikos, McDowell, A. & Nielsen, Hanne Mørck, 2021, In: ACS Applied Bio Materials. 4, 4, p. 3155-3165 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  85. Published

    Investigating to Optimal Ratio between Drug and Co-Former in Co-Amorphous Systems

    Rades, Thomas, 2021, In: Proceedings. 78, 1, 1 p., 27.

    Research output: Contribution to journal › Journal article › Research › peer-review

  86. Published

    Investigation into the role of the polymer in enhancing microwave-induced in situ amorphization

    Qiang, W., Löbmann, Korbinian, Knopp, Matthias Manne, McCoy, C. P., Andrews, G. P. & Zhao, M., 2021, In: International Journal of Pharmaceutics. 609, 8 p., 121157.

    Research output: Contribution to journal › Journal article › Research › peer-review

  87. Published

    Investigation on Formulation Strategies to Mitigate Compression-Induced Destabilization in Supersaturated Celecoxib Amorphous Solid Dispersions

    Bērziņš, Kārlis, Fraser-Miller, S. J., Walker, G. F., Rades, Thomas & Gordon, K. C., 2021, In: Molecular Pharmaceutics. 18, 10, p. 3882–3893

    Research output: Contribution to journal › Journal article › Research › peer-review

  88. Published

    Mechanochemical N-Chlorination Reaction of Hydantoin: In Situ Real-Time Kinetic Study by Powder X-ray Diffraction and Raman Spectroscopy

    Batista Martins, Inês Catarina, Carta, M., Haferkamp, S., Feiler, T., Delogu, F., Colacino, E. & Emmerling, F., 2021, In: ACS Sustainable Chemistry & Engineering. 9, 37, p. 12591-12601

    Research output: Contribution to journal › Journal article › Research › peer-review

  89. Published

    Microwave induced in situ amorphisation facilitated by crystalline hydrates

    Holm, T. P., Knopp, M. M., Löbmann, Korbinian & Berthelsen, R., 2021, In: European Journal of Pharmaceutical Sciences. 163, 9 p., 105858.

    Research output: Contribution to journal › Journal article › Research › peer-review

  90. Published

    Microwave-Induced in Situ Drug Amorphization Using a Mixture of Polyethylene Glycol and Polyvinylpyrrolidone

    Hempel, N. J., Knopp, Matthias Manne, Zeitler, J. A., Berthelsen, R. & Löbmann, Korbinian, 2021, In: Journal of Pharmaceutical Sciences. 110, 9, p. 3221-3229

    Research output: Contribution to journal › Journal article › Research › peer-review

  91. Published

    Monitoring the Isothermal Dehydration of Crystalline Hydrates Using Low-Frequency Raman Spectroscopy

    Robert, C., Fraser-Miller, S. J., Bērziņš, Kārlis, Okeyo, P. O., Rantanen, Jukka, Rades, Thomas & Gordon, K. C., 2021, In: Molecular Pharmaceutics. 18, 3, p. 1264-1276

    Research output: Contribution to journal › Journal article › Research › peer-review

  92. Published

    Predictive identification of co-formers in co-amorphous systems

    Chambers, L. I., Grohganz, Holger, Palmelund, H., Löbmann, Korbinian, Rades, Thomas, Musa, O. M. & Steed, J. W., 2021, In: European Journal of Pharmaceutical Sciences. 157, 9 p., 105636.

    Research output: Contribution to journal › Journal article › Research › peer-review

  93. Published

    Probabilistic modeling of an injectable aqueous crystalline suspension using influence networks

    Sekulovic, A., Petit, M., Verrijk, R., Rades, Thomas & Rantanen, Jukka, 2021, In: International Journal of Pharmaceutics. 596, 11 p., 120283.

    Research output: Contribution to journal › Journal article › Research › peer-review

  94. Published

    Screening of novel excipients for freeze-dried protein formulations

    Holm, T. P., Meng-Lund, H., Rantanen, Jukka, Jørgensen, Lene & Grohganz, Holger, 2021, In: European Journal of Pharmaceutics and Biopharmaceutics. 160, p. 55-64 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  95. Published

    Simultaneous automated image analysis and Raman spectroscopy of powders at an individual particle level

    Sekulovic, A., Verrijk, R., Rades, Thomas, Grabarek, A., Jiskoot, W., Hawe, A. & Rantanen, Jukka, 2021, In: Journal of Pharmaceutical and Biomedical Analysis. 193, 8 p., 113744.

    Research output: Contribution to journal › Journal article › Research › peer-review

  96. Published

    Studying the impact of the temperature and sorbed water during microwave-induced In Situ amorphization: A case study of celecoxib and polyvinylpyrrolidone

    Hempel, N. J., Knopp, Matthias Manne, Löbmann, Korbinian & Berthelsen, R., 2021, In: Pharmaceutics. 13, 6, 13 p., 886.

    Research output: Contribution to journal › Journal article › Research › peer-review

  97. Published

    The Influence of Drug-Polymer Solubility on Laser-Induced In Situ Drug Amorphization Using Photothermal Plasmonic Nanoparticles

    Hempel, N., Merkl, P., Knopp, Matthias Manne, Berthelsen, R., Teleki, A., Sotiriou, G. A. & Löbmann, Korbinian, 2021, In: Pharmaceutics. 13, 6, 12 p., 917.

    Research output: Contribution to journal › Journal article › Research › peer-review

  98. Published

    The Influence of Temperature and Viscosity of Polyethylene Glycol on the Rate of Microwave-Induced In Situ Amorphization of Celecoxib

    Hempel, N., Dao, T., Knopp, Matthias Manne, Berthelsen, R. & Löbmann, Korbinian, 2021, In: Molecules. 26, 1, 8 p., 110.

    Research output: Contribution to journal › Journal article › Research › peer-review

  99. Published

    The Use of Glycerol as an Enabling Excipient for Microwave-Induced In Situ Drug Amorphization

    Hempel, N., Morsch, F., Knopp, Matthias Manne, Berthelsen, R. & Löbmann, Korbinian, 2021, In: Journal of Pharmaceutical Sciences. 110, 1, p. 155-163 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  100. Published

    The influence of moisture on the storage stability of co-amorphous systems

    Liu, J., Rades, Thomas & Grohganz, Holger, 2021, In: International Journal of Pharmaceutics. 605, 120802.

    Research output: Contribution to journal › Journal article › Research › peer-review

  101. Published

    Utilizing Laser Activation of Photothermal Plasmonic Nanoparticles to Induce On-Demand Drug Amorphization inside a Tablet

    Hempel, N. J., Merkl, P., Asad, S., Knopp, M. M., Berthelsen, R., Bergström, C. A. S., Teleki, A., Sotiriou, G. A. & Löbmann, Korbinian, 2021, In: Molecular Pharmaceutics. 18, 6, p. 2254–2262

    Research output: Contribution to journal › Journal article › Research › peer-review

  102. Published

    Vancomycin-Loaded Microneedle Arrays against Methicillin-Resistant Staphylococcus Aureus Skin Infections

    Ziesmer, J., Tajpara, P., Hempel, N., Ehrstrom, M., Melican, K., Eidsmo, Liv & Sotiriou, G. A., 2021, In: Advanced Materials Technologies. 10 p., 2001307.

    Research output: Contribution to journal › Journal article › Research › peer-review

  103. Published

    X-ray Imaging for Gastrointestinal Tracking of Microscale Oral Drug Delivery Devices

    Kjeldsen, R. B., Kristensen, M. N., Gundlach, C., Thamdrup, L. H. E., Mullertz, Anette , Rades, Thomas, Nielsen, L. H., Zór, K. & Boisen, A., 2021, In: ACS Biomaterials Science and Engineering. 7, 6, p. 2538–2547

    Research output: Contribution to journal › Journal article › Research › peer-review

  104. 2020
  105. Published

    Effect of supersaturation on absorption of indomethacin and tadalafil in a single pass intestinal perfusion rat model, in the absence and presence of a precipitation inhibitor

    Strindberg, S., Plum, J., Stie, Mai Bay, Christiansen, M. L., Nielsen, L. H., Rades, Thomas & Mullertz, Anette , Jun 2020, In: European Journal of Pharmaceutics and Biopharmaceutics. 151, p. 108-115

    Research output: Contribution to journal › Journal article › Research › peer-review

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