Solid State Pharmaceutics

  1. Published

    (Co-)amorphization of enantiomers – Investigation of the amorphization process, the physical stability and the dissolution behavior

    Holzapfel, K., Liu, J., Rades, Thomas & Leopold, C. S., 2022, In: International Journal of Pharmaceutics. 616, 9 p., 121552.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    In vitro-in vivo relationship for amorphous solid dispersions using a double membrane dissolution-permeation setup

    Jørgensen, J. R., Mohr, W., Rischer, M., Sauer, A., Mistry, S., Rades, Thomas & Mullertz, Anette , 2023, In: European Journal of Pharmaceutics and Biopharmaceutics. 188, p. 26-32

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    A Comparative Study between A Protein Based Amorphous Formulation and Other Dissolution Rate Enhancing Approaches: A Case Study with Rifaximin

    Zhuo, Xuezhi, Margrethe Brekstad Kjellin, M., Schaal, Z., Zhang, T., Löbmann, Korbinian & Leng, D., 2023, In: Pharmaceutics. 15, 1, 10 p., 126.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    A Multivariate Approach for the Determination of the Optimal Mixing Ratio of the Non-Strong Interacting Co-Amorphous System Carvedilol-Tryptophan

    Di, Rong, Liu, J., Grohganz, Holger & Rades, Thomas, 2021, In: Molecules. 26, 4, 8 p., 801.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    A Platform for Preparing Homogeneous Proteinaceous Subvisible Particles With Distinct Morphologies

    Schack, M. M., Moller, E. H., Carpenter, J. F., Rades, Thomas & Groenning, M., Jul 2018, In: Journal of Pharmaceutical Sciences. 107, 7, p. 1842-1851

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    A co-amorphous form of a substance and a protein

    Mishra, J., Bohr, A., Berg, T. H. A., Löbmann, Korbinian, Rades, Thomas, Grohganz, Holger & Water, J. J., 2019, Patent No. US201903078886A1

    Research output: Patent

  7. Published

    A comparison of pseudo-ternary diagrams of aqueous mixtures of Quil A, cholesterol and phospholipid prepared by lipid-film hydration and dialysis

    Demana, P. H., Davies, N. M., Berger, B., Vosgerau, U. & Rades, Thomas, May 2004, In: Journal of Pharmacy and Pharmacology. 56, 5, p. 573-580 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    A fast and reliable DSC-based method to determine the monomolecular loading capacity of drugs with good glass-forming ability in mesoporous silica

    Hempel, N., Brede, K., Olesen, N. E., Genina, Natalja, Knopp, Matthias Manne & Löbmann, Korbinian, 18 Apr 2018, In: International Journal of Pharmaceutics. 544, 1, p. 153-57

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    A new method for the determination of the unfrozen matrix concentration and the maximal freeze-concentration

    Liesebach, J., Rades, Thomas & Lim, M., 19 May 2003, In: Thermochimica Acta. 401, 2, p. 159-168 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    A new method to determine drug-polymer solubility through enthalpy of melting and mixing

    Meiland, Peter, Larsen, B. S., Knopp, Matthias Manne, Tho, I. & Rades, Thomas, 2022, In: International Journal of Pharmaceutics. 629, 9 p., 122391.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    A non-destructive method for quality control of the pellet distribution within a MUPS tablet by terahertz pulsed imaging

    Novikova, A., Markl, D., Axel Zeitler, J., Rades, Thomas & Leopold, C. S., Jan 2018, In: European Journal of Pharmaceutical Sciences. 111, p. 549-555

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    A theoretical and spectroscopic study of carbamazepine polymorphs

    Strachan, C. J., Howell, S. L., Rades, Thomas & Gordon, K. C., May 2004, In: Journal of Raman Spectroscopy. 35, 5, p. 401-408 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Acheta domesticus: A Natural Source of Anti-Skin-Aging Ingredients for Cosmetic Applications

    Yeerong, K., Chantawannakul, P., Anuchapreeda, S., Rades, Thomas, Mullertz, Anette & Chaiyana, W., 2024, In: Pharmaceuticals. 17, 3, 20 p., 346.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Addition of Cationic Surfactants to Lipid-Based Formulations of Poorly Water-Soluble Acidic Drugs Alters the Phase Distribution and the Solid-State Form of the Precipitate Upon In Vitro Lipolysis

    Khan, J., Rades, Thomas & Boyd, Ben, Sep 2018, In: Journal of Pharmaceutical Sciences. 107, 9, p. 2420-2427 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Additive manufacturing in respiratory sciences – Current applications and future prospects

    Bock, S., Rades, Thomas, Rantanen, Jukka & Scherließ, R., 2022, In: Advanced Drug Delivery Reviews. 186, 14 p., 114341.

    Research output: Contribution to journalReviewResearchpeer-review

  16. Published

    Advances in lipid-based subunit vaccine formulations

    Myschik, J., Rades, Thomas & Hook, S., 2009, In: Current Immunology Reviews.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Amino acids as stabilizers for spray-dried simvastatin powder for inhalation

    Lu, W., Rades, Thomas, Rantanen, Jukka, Chan, H. & Yang, Mingshi, 2020, In: International Journal of Pharmaceutics. 572, 12 p., 118724.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Amorphization of different furosemide polymorphic forms during ball milling: Tracking solid-to-solid phase transformations

    Wang, M., Gong, J., Rades, Thomas & Batista Martins, Inês Catarina, 2023, In: International Journal of Pharmaceutics. 648, 9 p., 123573.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Amorphous drug stabilization using mesoporous materials

    Veloso, D. F. M. C., Knopp, Matthias Manne & Löbmann, Korbinian, 2020, Drug delivery trends. Elsevier, Vol. 3. p. 151-166

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  20. Published

    Amorphous drugs and dosage forms

    Grohganz, Holger, Löbmann, Korbinian, Priemel, P., Tarp Jensen, K., Graeser, K., Strachan, C. & Rades, Thomas, 2013, In: Journal of Drug Delivery Science and Technology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Analysis of lecithin-cholesterol mixtures using Raman spectroscopy

    Tantipolphan, R., Rades, Thomas, Strachan, C. J., Gordon, K. C. & Medlicott, N. J., 2006, In: Journal of Pharmaceutical and Biomedical Analysis.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Analysis of stabilization mechanisms in β-lactoglobulin-based amorphous solid dispersions by experimental and computational approaches

    Zhuo, Xuezhi, Foderà, Vito, Larsson, P., Schaal, Z., Bergström, C. A. S., Löbmann, Korbinian & Kabedev, A., 2024, In: European Journal of Pharmaceutical Sciences. 192, 13 p., 106639.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Anti-plasticizing effect of water on prilocaine and lidocaine: the role of the hydrogen bonding pattern

    Xu, X., Grohganz, Holger & Rades, Thomas, 2024, In: Physical Chemistry Chemical Physics. 26, p. 14149-14159

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Application of a Salt Coformer in a Co-Amorphous Drug System Dramatically Enhances the Glass Transition Temperature: A Case Study of the Ternary System Carbamazepine, Citric Acid, and L-Arginine

    Ueda, H., Wu, W., Löbmann, Korbinian, Grohganz, Holger, Mullertz, Anette & Rades, Thomas, May 2018, In: Molecular Pharmaceutics. 15, 5, p. 2036-2044

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Application of pharmaceutical drug delivery for biological control of the common brushtail possum in New Zealand: A review

    McDowell, A., McLeod, B. J., Rades, Thomas & Tucker, I. G., 2006, In: Wildlife Research.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Applications of Raman spectroscopy in aqueous environments

    Sandler, N., Savolainen, M., Saupe, A., Strachan, C. & Rades, Thomas, 2007, In: Pharmaceutical Technology Europe.

    Research output: Contribution to journalJournal articleResearch

  27. Published

    Are phytosomes a superior nanodelivery system for the antioxidant rutin?

    Vu, H. T. H., Hook, S. M., Siqueira, S. D., Mullertz, Anette , Rades, Thomas & McDowell, A., 2018, In: International Journal of Pharmaceutics. 548, 1, p. 82-91 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Aspartame as a co-former in co-amorphous systems

    Wu, W., Löbmann, Korbinian, Schnitzkewitz, J., Knuhtsen, A., Pedersen, D. S., Grohganz, Holger & Rades, Thomas, 5 Oct 2018, In: International Journal of Pharmaceutics. 549, 1-2, p. 380-387

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Assessing acute colitis induced by dextran sulfate sodium in rats and its impact on gastrointestinal fluids

    Klitgaard, Mette, Kristensen, M. N., Venkatasubramanian, R., Guerra, Priscila Regina, Jacobsen, Jette, Berthelsen, R., Rades, Thomas & Mullertz, Anette , 2023, In: Drug Delivery and Translational Research. 13, p. 1484–1499

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Biorelevant intrinsic dissolution profiling in early drug development: Fundamental, methodological, and industrial aspects

    Bergstrom, C. A. S., Box, K., Holm, R., Matthews, W., McAllister, M., Mullertz, Anette , Rades, Thomas, Schaefer, K. J. & Teleki, A., Jun 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 139, p. 101-114

    Research output: Contribution to journalReviewResearchpeer-review

  31. Published

    Cage-like complexes formed by DOTAP, Quil-A and cholesterol

    Lendemans, D. G., Egert, A. M., Hook, S. & Rades, Thomas, 2007, In: International Journal of Pharmaceutics.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Characterisation of bicontinuous cubic liquid crystalline systems of phytantriol and water using cryo field emission scanning electron microscopy (cryo FESEM)

    Rizwan, S. B., Dong, Y., Boyd, Ben, Rades, Thomas & Hook, S., 2007, In: Micron.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Characterisation of microemulsions containing orange oil with water and propylene glycol as hydrophilic components

    Yotsawimonwat, S., Okonoki, S., Krauel, K., Sirithunyalug, J., Sirithunyalug, B. & Rades, Thomas, 2006, In: Pharmazie.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Characterisation of microstructures formed in isopropyl palmitate/water/Aerosol®OT: 1-butanol (2:1) system

    Boonme, P., Krauel, K., Graf, A., Rades, Thomas & Junyaprasert, V. B., 2006, In: Pharmazie.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Characterisation of pore structures of pharmaceutical tablets: A review

    Markl, D., Strobel, A., Schlossnikl, R., Bøtker, Johan Peter, Bawuah, P., Ridgway, C., Rantanen, Jukka, Rades, Thomas, Gane, P., Peiponen, K. & Zeitler, J. A., 5 Jan 2018, In: International Journal of Pharmaceutics. 538, 1, p. 188-214 27 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Characterisation of quaternary polymethacrylate films containing tartaric acid, metoprolol free base or metoprolol tartrate

    Glaessl, B., Siepmann, F., Tucker, I., Siepmann, J. & Rades, Thomas, 2009, In: European Journal of Pharmaceutics and Biopharmaceutics.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Characterising glass transition temperatures and glass dynamics in mesoporous silica-based amorphous drugs

    Kissi, E. O., Ruggiero, M. T., Hempel, N. J., Song, Z., Grohganz, Holger, Rades, Thomas & Löbmann, Korbinian, 1 Jan 2019, In: Physical Chemistry Chemical Physics. 21, 35, p. 19686-19694 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Characterization of a commercial liposome spray

    Rades, Thomas, Gerke, A., Schütze, W. & Müller-Goymann, C. C., 1997, In: Pharmazie.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Characterization of glass solutions of poorly water-soluble drugs produced by melt extrusion with hydrophilic amorphous polymers

    Forster, A., Hempenstall, J. & Rades, Thomas, 2001, In: Journal of Pharmacy and Pharmacology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Characterization of the hydrodynamics in a miniaturized dissolution apparatus

    Johansson, Kristoffer Enøe, Plum, J., Mosleh, M., Madsen, C. M., Rades, Thomas & Mullertz, Anette , 2018, In: Journal of Pharmaceutical Sciences. 107, 4, p. 1095-1103 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Characterizing colloidal structures of pseudoternary phase diagrams formed by oil/water/amphiphile systems

    Alany, R. G., Tucker, I. G., Davies, N. M. & Rades, Thomas, 2001, In: Drug Development and Industrial Pharmacy.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Characterizing the conversion kinetics of carbamazepine polymorphs to the dihydrate in aqueous suspension using Raman spectroscopy

    Tian, F., Zeitler, J. A., Strachan, C. J., Saville, D. J., Gordon, K. C. & Rades, Thomas, 2006, In: Journal of Pharmaceutical and Biomedical Analysis.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published
  44. Published

    Co-amorphous systems consisting of indomethacin and the chiral co-former tryptophan: Solid-state properties and molecular mobilities

    Holzapfel, K., Rades, Thomas & Leopold, C. S., 2023, In: International Journal of Pharmaceutics. 636, 12 p., 122840.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Co-former selection for co-amorphous drug-amino acid formulations

    Kasten, G., Löbmann, Korbinian, Grohganz, Holger & Rades, Thomas, 2019, In: International Journal of Pharmaceutics. 557, p. 366-373

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Coaxial electrospinning of polycaprolactone: A design of experiments approach

    Gürtler, Anna-Lena, Linseisen, I., Grohganz, Holger & Heinz, Andrea, 2024, In: European Polymer Journal. 208, 11 p., 112886.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Combined Effect of the Preparation Method and Compression on the Physical Stability and Dissolution Behavior of Melt-Quenched Amorphous Celecoxib

    Bērziņš, Kārlis, Fraser-Miller, S. J., Di, Rong, Liu, J., Peltonen, L., Strachan, C. J., Rades, Thomas & Gordon, K. C., 2021, In: Molecular Pharmaceutics. 18, 3, p. 1408-1418

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Combining diagnostic methods for antimicrobial susceptibility testing – A comparative approach

    Klodzinska, S. N., Priemel, P. A., Rades, Thomas & Nielsen, Hanne Mørck, Jan 2018, In: Journal of Microbiological Methods. 144, p. 177-185

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Combining lipid based drug delivery and amorphous solid dispersions for improved oral drug absorption of a poorly water-soluble drug

    Nora, G., Venkatasubramanian, R., Strindberg, S., Siqueira-Jørgensen, S. D., Pagano, L., Romanski, F. S., Swarnakar, N. K., Rades, Thomas & Mullertz, Anette , 2022, In: Journal of Controlled Release. 349, p. 206-212

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Compaction Behavior of Co-Amorphous Systems

    Sørensen, C. M., Rantanen, Jukka & Grohganz, Holger, 2023, In: Pharmaceutics. 15, 3, 12 p., 858.

    Research output: Contribution to journalJournal articleResearchpeer-review

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