Solid State Pharmaceutics

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  1. 2020
  2. Published

    Microwave-Induced In Situ Amorphization: A New Strategy for Tackling the Stability Issue of Amorphous Solid Dispersions

    Qiang, W., Löbmann, Korbinian, McCoy, C. P., Andrews, G. P. & Zhao, M., 2020, In: Pharmaceutics. 12, 7, 19 p., 655.

    Research output: Contribution to journal › Review › Research › peer-review

  3. Published

    Preparation of Co-Amorphous Systems by Freeze-Drying

    Wostry, M., Plappert, H. & Grohganz, Holger, 2020, In: Pharmaceutics. 12, 10, 12 p., 941.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Simultaneous investigation of the liquid transport and swelling performance during tablet disintegration

    Al-Sharabi, M., Markl, D., Mudley, T., Bawuah, P., Karttunen, A., Ridgway, C., Gane, P., Ketolainen, J., Peiponen, K., Rades, Thomas & Zeitler, J. A., 2020, In: International Journal of Pharmaceutics. 584, 11 p., 119380.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Single particles as resonators for thermomechanical analysis

    Okeyo, P. O., Larsen, P. E., Kissi, E. O., Ajalloueian, F., Rades, Thomas, Rantanen, Jukka & Boisen, A., 2020, In: Nature Communications. 11, 1, 11 p., 1235.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Solving the Computational Puzzle: Toward a Pragmatic Pathway for Modeling Low-Energy Vibrational Modes of Pharmaceutical Crystals

    Bērziņš, Kārlis, Sutton, J. J., Fraser-Miller, S. J., Rades, Thomas, Korter, T. M. & Gordon, K. C., 2020, In: Crystal Growth & Design. 20, 10, p. 6947-6955

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Temperature-Modulated Micromechanical Thermal Analysis with Microstring Resonators Detects Multiple Coherent Features of Small Molecule Glass Transition

    Karl, M., Thamdrup, L. H. E., Rantanen, Jukka, Boisen, A. & Rades, Thomas, 2020, In: Sensors. 20, 4, 14 p., 1019.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Using in vitro lipolysis and SPECT/CT in vivo imaging to understand oral absorption of fenofibrate from lipid-based drug delivery systems

    Tran, T., Bonlokke, P., Rodriguez-Rodriguez, C., Nosrati, Z., Esquinas, P. L., Borkar, N., Plum, J., Strindberg, S., Karagiozov, S., Rades, Thomas, Mullertz, Anette , Saatchi, K. & Hafeli, U. O., 2020, In: Journal of Controlled Release. 317, p. 375-384

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. 2019
  10. Published

    Determining Thermal Conductivity of Small Molecule Amorphous Drugs with Modulated Differential Scanning Calorimetry and Vacuum Molding Sample Preparation

    Karl, M., Rantanen, Jukka & Rades, Thomas, 6 Dec 2019, In: Pharmaceutics. 11, 12, 7 p., 670.

    Research output: Contribution to journal › Journal article › Communication

  11. Published

    The role interplay between mesoporous silica pore volume and surface area and their effect on drug loading capacity

    Bavnhøj, C. G., Knopp, Matthias Manne, Madsen, C. & Löbmann, Korbinian, 1 Dec 2019, In: International Journal of Pharmaceutics: X. 1, 5 p., 100008.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Comparison of bulk and microfluidics methods for the formulation of poly-lactic-co-glycolic acid (PLGA) nanoparticles modified with cell-penetrating peptides of different architectures

    Streck, S., Neumann, H., Nielsen, Hanne Mørck, Rades, Thomas & McDowell, A., Dec 2019, In: International Journal of Pharmaceutics: X. 1, 9 p., 100030.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Spray-drying of inhalable, multifunctional formulations for the treatment of biofilms formed in cystic fibrosis

    Lababidi, N., Kissi, E. O., Elgaher, W. A. M., Sigal, V., Haupenthal, J., Schwarz, B. C., Hirsch, A. K. H., Rades, Thomas & Schneider, M., 28 Nov 2019, In: Journal of Controlled Release. 314, p. 62-71

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    The distribution of cell-penetrating peptides on polymeric nanoparticles prepared using microfluidics and elucidated with small angle X-ray scattering

    Streck, S., Clulow, A. J., Nielsen, Hanne Mørck, Rades, Thomas, Boyd, B. J. & McDowell, A., 1 Nov 2019, In: Journal of Colloid and Interface Science. 555, p. 438-448 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Utilizing nanoparticles for improving anti-biofilm effects of azithromycin: A head-to-head comparison of modified hyaluronic acid nanogels and coated poly (lactic-co-glycolic acid) nanoparticles

    Kłodzińska, S. N., Wan, F., Jumaa, H., Sternberg, C., Rades, Thomas & Nielsen, Hanne Mørck, 1 Nov 2019, In: Journal of Colloid and Interface Science. 555, p. 595-606 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Inhalable co-amorphous budesonide-arginine dry powders prepared by spray drying

    Lu, W., Rades, Thomas, Rantanen, Jukka & Yang, Mingshi, 30 Jun 2019, In: International Journal of Pharmaceutics. 565, p. 1-8 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    In vitro digestion models to evaluate lipid based drug delivery systems; present status and current trends

    Berthelsen, R., Klitgaard, Mette, Rades, Thomas & Mullertz, Anette , 29 Jun 2019, In: Advanced Drug Delivery Reviews. 142, p. 35-49 15 p.

    Research output: Contribution to journal › Review › Research › peer-review

  18. Published

    Direct Measurement of Amorphous Solubility

    Stukelj, J., Svanback, S., Agopov, M., Löbmann, Korbinian, Strachan, C. J., Rades, Thomas & Yliruusi, J., 4 Jun 2019, In: Analytical Chemistry. 91, 11, p. 7411-7417

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Biorelevant intrinsic dissolution profiling in early drug development: Fundamental, methodological, and industrial aspects

    Bergstrom, C. A. S., Box, K., Holm, R., Matthews, W., McAllister, M., Mullertz, Anette , Rades, Thomas, Schaefer, K. J. & Teleki, A., Jun 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 139, p. 101-114

    Research output: Contribution to journal › Review › Research › peer-review

  20. Published

    Imaging of dehydration in particulate matter using Raman line-focus microscopy

    Okeyo, P. O., Ilchenko, O., Slipets, R., Larsen, P. E., Boisen, A., Rades, Thomas & Rantanen, Jukka, 17 May 2019, In: Scientific Reports. 9, 11 p., 7525.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Direct Comparison of Standard Transmission Electron Microscopy and Cryogenic-TEM in Imaging Nanocrystals Inside Liposomes

    Li, T., Nowell, C. J., Cipolla, D., Rades, Thomas & Boyd, B. J., Apr 2019, In: Molecular Pharmaceutics. 16, 4, p. 1775-1781

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    In situ co-amorphisation in coated tablets – The combination of carvedilol with aspartic acid during immersion in an acidic medium

    Petry, I., Löbmann, Korbinian, Grohganz, Holger, Rades, Thomas & Leopold, C. S., 10 Mar 2019, In: International Journal of Pharmaceutics. 558, p. 357-366 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Design of Inhalable Solid Dosage Forms of Budesonide and Theophylline for Pulmonary Combination Therapy

    Leng, D., Kissi, E. O., Löbmann, Korbinian, Thanki, K., Fattal, E., Rades, Thomas, Foged, Camilla & Yang, Mingshi, 7 Mar 2019, In: AAPS PharmSciTech. 20, 3, 137.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Transformations between Co-Amorphous and Co-Crystal Systems and Their Influence on the Formation and Physical Stability of Co-Amorphous Systems

    Wu, W., Wang, Y., Löbmann, Korbinian, Grohganz, Holger & Rades, Thomas, 4 Mar 2019, In: Molecular Pharmaceutics. 16, 3, p. 1294-1304 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Whey proteins as stabilizers in amorphous solid dispersions

    Mishra, J., Bohr, A., Rades, Thomas, Grohganz, Holger & Löbmann, Korbinian, 1 Feb 2019, In: European Journal of Pharmaceutical Sciences. 128, p. 144-151 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Process Optimization and Upscaling of Spray-Dried Drug-Amino acid Co-Amorphous Formulations

    Kasten, G., Duarte, Í., Paisana, M., Löbmann, Korbinian, Rades, Thomas & Grohganz, Holger, 9 Jan 2019, In: Pharmaceutics. 11, 1, 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Characterising glass transition temperatures and glass dynamics in mesoporous silica-based amorphous drugs

    Kissi, E. O., Ruggiero, M. T., Hempel, N. J., Song, Z., Grohganz, Holger, Rades, Thomas & Löbmann, Korbinian, 1 Jan 2019, In: Physical Chemistry Chemical Physics. 21, 35, p. 19686-19694 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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