- 2021
- Published
Vancomycin-Loaded Microneedle Arrays against Methicillin-Resistant Staphylococcus Aureus Skin Infections
Ziesmer, J., Tajpara, P., Hempel, N., Ehrstrom, M., Melican, K., Eidsmo, Liv & Sotiriou, G. A., 2021, In: Advanced Materials Technologies. 10 p., 2001307.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
X-ray Imaging for Gastrointestinal Tracking of Microscale Oral Drug Delivery Devices
Kjeldsen, R. B., Kristensen, M. N., Gundlach, C., Thamdrup, L. H. E., Mullertz, Anette , Rades, Thomas, Nielsen, L. H., Zór, K. & Boisen, A., 2021, In: ACS Biomaterials Science and Engineering. 7, 6, p. 2538–2547Research output: Contribution to journal › Journal article › Research › peer-review
- 2020
- Published
Effect of supersaturation on absorption of indomethacin and tadalafil in a single pass intestinal perfusion rat model, in the absence and presence of a precipitation inhibitor
Strindberg, S., Plum, J., Stie, Mai Bay, Christiansen, M. L., Nielsen, L. H., Rades, Thomas & Mullertz, Anette , Jun 2020, In: European Journal of Pharmaceutics and Biopharmaceutics. 151, p. 108-115Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The influence of drug and polymer particle size on the in situ amorphization using microwave irradiation
Hempel, N. J., Knopp, Matthias Manne, Berthelsen, R., Zeitler, J. A. & Löbmann, Korbinian, Apr 2020, In: European Journal of Pharmaceutics and Biopharmaceutics. 149, p. 77-84 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Poorly soluble drugs
Siepmann, J., Rades, Thomas, Mullertz, Anette & Loftsson, T., 15 Mar 2020, In: International Journal of Pharmaceutics. 577, 119055.Research output: Contribution to journal › Editorial › Research
- Published
In Vitro, Ex Vivo and In Vivo Evaluation of Microcontainers for Oral Delivery of Insulin
Jørgensen, J. R., Yu, F., Ramakrishnan, V., Nielsen, L. H., Nielsen, Hanne Mørck, Boisen, A., Rades, Thomas & Mullertz, Anette , 7 Jan 2020, In: Pharmaceutics. 12, 1, 14 p., 48.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparison of induction methods for supersaturation: pH shift versus solvent shift
Plum, J., Bavnhoj, C., Palmelund, H., Perez-Alos, L., Mullertz, Anette & Rades, Thomas, 5 Jan 2020, In: International Journal of Pharmaceutics. 573, 8 p., 118862.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Amino acids as stabilizers for spray-dried simvastatin powder for inhalation
Lu, W., Rades, Thomas, Rantanen, Jukka, Chan, H. & Yang, Mingshi, 2020, In: International Journal of Pharmaceutics. 572, 12 p., 118724.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Amorphous drug stabilization using mesoporous materials
Veloso, D. F. M. C., Knopp, Matthias Manne & Löbmann, Korbinian, 2020, Drug delivery trends. Elsevier, Vol. 3. p. 151-166Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Comparison of induction methods for supersaturation: Amorphous dissolution versus solvent shift
Plum, J., Bavnhoj, C. G., Eliasen, Jannik Nicklas, Rades, Thomas & Mullertz, Anette , 2020, In: European Journal of Pharmaceutics and Biopharmaceutics. 152, p. 35-43 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Constraints on CaCO3 precipitation in superabsorbent polymer by aerobic bacteria
Nielsen, S. D., Koren, K., Löbmann, Korbinian, Hinge, M., Scoma, A., Kjeldsen, K. U. & Roy, H., 2020, In: Applied Microbiology and Biotechnology. 104, 1, p. 365-375Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Convection-Induced vs. Microwave Radiation-Induced in situ Drug Amorphization
Hempel, N., Knopp, Matthias Manne, Berthelsen, R. & Löbmann, Korbinian, 2020, In: Molecules. 25, 5, 7 p., 1068.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Data-enriched edible pharmaceuticals (DEEP) of medical cannabis by inkjet printing
Öblom, H., Cornett, Claus, Bøtker, Johan Peter, Frøkjær, Sven, Hansen, Harald S., Rades, Thomas, Rantanen, Jukka & Genina, Natalja, 2020, In: International Journal of Pharmaceutics. 589, p. 1-11 119866.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Determination of the Optimal Molar Ratio in Amino Acid-Based Coamorphous Systems
Liu, J., Rades, Thomas & Grohganz, Holger, 2020, In: Molecular Pharmaceutics. 17, 4, p. 1335-1342 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Direct Measurement of Lateral Molecular Diffusivity on the Surface of Supersaturated Amorphous Solid Dispersions by Atomic Force Microscopy
Bannow, J., Karl, M., Larsen, P. E., Hwu, E. T. & Rades, Thomas, 2020, In: Molecular Pharmaceutics. 17, 5, p. 1715-1722 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Enhancing Stability and Tooth Bleaching Activity of Carbamide Peroxide by Electrospun Nanofibrous Film
Okonogi, S., Kaewpinta, A., Rades, Thomas, Mullertz, Anette , Yang, Mingshi, Khongkhunthian, S. & Chaijareenont, P., 2020, In: Pharmaceuticals. 13, 11, 20 p., 381.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exposure of liposomes containing nanocrystallised ciprofloxacin to digestive media induces solid-state transformation and altered in vitro drug release
Li, T., Hawley, A., Rades, Thomas & Boyd, B. J., 2020, In: Journal of Controlled Release. 323, p. 350-360 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Formulation of co-amorphous systems from naproxen and naproxen sodium and in situ monitoring of physicochemical state changes during dissolution testing by Raman spectroscopy
Ueda, H., Bøtker, Johan Peter, Edinger, M., Löbmann, Korbinian, Grohganz, Holger, Mullertz, Anette , Rades, Thomas & Østergaard, Jesper, 2020, In: International Journal of Pharmaceutics. 587, 119662.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Functionalised calcium carbonate as a coformer to stabilize amorphous drugs by mechanochemical activation
Liu, J., Rades, Thomas, Tho, I. & Kissi, E. O., 2020, In: European Journal of Pharmaceutics and Biopharmaceutics. 155, p. 22-28 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Highly Elastic and Water Stable Zein Microfibers as a Potential Drug Delivery System for Wound Healing
Akhmetova, A., Lanno, G., Kogermann, K., Malmsten, Martin, Rades, Thomas & Heinz, Andrea, 2020, In: Pharmaceutics. 12, 5, 19 p., 458.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hot Melt Coating of Amorphous Carvedilol
Bannow, J., Koren, L., Salar-Behzadi, S., Löbmann, Korbinian, Zimmer, A. & Rades, Thomas, 2020, In: Pharmaceutics. 12, 6, 13 p., 519.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Improving the drug load and in vitro performance of supersaturated self-nanoemulsifying drug delivery systems (super-SNEDDS) using polymeric precipitation inhibitors
Bannow, J., Yorulmaz, Y., Löbmann, Korbinian, Mullertz, Anette & Rades, Thomas, 2020, In: International Journal of Pharmaceutics. 575, 1188960.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of polymer addition on the amorphization, dissolution and physical stability of co-amorphous systems
Liu, J., Grohganz, Holger & Rades, Thomas, 2020, In: International Journal of Pharmaceutics. 588, p. 1-9 9 p., 119768.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of the Polymer Glass Transition Temperature and Molecular Weight on Drug Amorphization Kinetics Using Ball Milling
Asgreen, Camilla Jantzen, Knopp, Matthias Manne, Skytte, J. & Löbmann, Korbinian, 2020, In: Pharmaceutics. 12, 6, 6 p., 483.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of water of crystallization on the ternary phase behavior of a drug and deep eutectic solvent
Palmelund, H., Boyd, B. J., Rantanen, Jukka & Löbmann, Korbinian, 2020, In: Journal of Molecular Liquids. 315, p. 1-7 113727.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Microwave-Induced In Situ Amorphization: A New Strategy for Tackling the Stability Issue of Amorphous Solid Dispersions
Qiang, W., Löbmann, Korbinian, McCoy, C. P., Andrews, G. P. & Zhao, M., 2020, In: Pharmaceutics. 12, 7, 19 p., 655.Research output: Contribution to journal › Review › Research › peer-review
- Published
Preparation of Co-Amorphous Systems by Freeze-Drying
Wostry, M., Plappert, H. & Grohganz, Holger, 2020, In: Pharmaceutics. 12, 10, 12 p., 941.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Simultaneous investigation of the liquid transport and swelling performance during tablet disintegration
Al-Sharabi, M., Markl, D., Mudley, T., Bawuah, P., Karttunen, A., Ridgway, C., Gane, P., Ketolainen, J., Peiponen, K., Rades, Thomas & Zeitler, J. A., 2020, In: International Journal of Pharmaceutics. 584, 11 p., 119380.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Single particles as resonators for thermomechanical analysis
Okeyo, P. O., Larsen, P. E., Kissi, E. O., Ajalloueian, F., Rades, Thomas, Rantanen, Jukka & Boisen, A., 2020, In: Nature Communications. 11, 1, 11 p., 1235.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Solving the Computational Puzzle: Toward a Pragmatic Pathway for Modeling Low-Energy Vibrational Modes of Pharmaceutical Crystals
Bērziņš, Kārlis, Sutton, J. J., Fraser-Miller, S. J., Rades, Thomas, Korter, T. M. & Gordon, K. C., 2020, In: Crystal Growth & Design. 20, 10, p. 6947-6955Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Temperature-Modulated Micromechanical Thermal Analysis with Microstring Resonators Detects Multiple Coherent Features of Small Molecule Glass Transition
Karl, M., Thamdrup, L. H. E., Rantanen, Jukka, Boisen, A. & Rades, Thomas, 2020, In: Sensors. 20, 4, 14 p., 1019.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Using in vitro lipolysis and SPECT/CT in vivo imaging to understand oral absorption of fenofibrate from lipid-based drug delivery systems
Tran, T., Bonlokke, P., Rodriguez-Rodriguez, C., Nosrati, Z., Esquinas, P. L., Borkar, N., Plum, J., Strindberg, S., Karagiozov, S., Rades, Thomas, Mullertz, Anette , Saatchi, K. & Hafeli, U. O., 2020, In: Journal of Controlled Release. 317, p. 375-384Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
Determining Thermal Conductivity of Small Molecule Amorphous Drugs with Modulated Differential Scanning Calorimetry and Vacuum Molding Sample Preparation
Karl, M., Rantanen, Jukka & Rades, Thomas, 6 Dec 2019, In: Pharmaceutics. 11, 12, 7 p., 670.Research output: Contribution to journal › Journal article › Communication
- Published
The role interplay between mesoporous silica pore volume and surface area and their effect on drug loading capacity
Bavnhøj, C. G., Knopp, Matthias Manne, Madsen, C. & Löbmann, Korbinian, 1 Dec 2019, In: International Journal of Pharmaceutics: X. 1, 5 p., 100008.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparison of bulk and microfluidics methods for the formulation of poly-lactic-co-glycolic acid (PLGA) nanoparticles modified with cell-penetrating peptides of different architectures
Streck, S., Neumann, H., Nielsen, Hanne Mørck, Rades, Thomas & McDowell, A., Dec 2019, In: International Journal of Pharmaceutics: X. 1, 9 p., 100030.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Spray-drying of inhalable, multifunctional formulations for the treatment of biofilms formed in cystic fibrosis
Lababidi, N., Kissi, E. O., Elgaher, W. A. M., Sigal, V., Haupenthal, J., Schwarz, B. C., Hirsch, A. K. H., Rades, Thomas & Schneider, M., 28 Nov 2019, In: Journal of Controlled Release. 314, p. 62-71Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The distribution of cell-penetrating peptides on polymeric nanoparticles prepared using microfluidics and elucidated with small angle X-ray scattering
Streck, S., Clulow, A. J., Nielsen, Hanne Mørck, Rades, Thomas, Boyd, B. J. & McDowell, A., 1 Nov 2019, In: Journal of Colloid and Interface Science. 555, p. 438-448 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Utilizing nanoparticles for improving anti-biofilm effects of azithromycin: A head-to-head comparison of modified hyaluronic acid nanogels and coated poly (lactic-co-glycolic acid) nanoparticles
Kłodzińska, S. N., Wan, F., Jumaa, H., Sternberg, C., Rades, Thomas & Nielsen, Hanne Mørck, 1 Nov 2019, In: Journal of Colloid and Interface Science. 555, p. 595-606 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhalable co-amorphous budesonide-arginine dry powders prepared by spray drying
Lu, W., Rades, Thomas, Rantanen, Jukka & Yang, Mingshi, 30 Jun 2019, In: International Journal of Pharmaceutics. 565, p. 1-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In vitro digestion models to evaluate lipid based drug delivery systems; present status and current trends
Berthelsen, R., Klitgaard, Mette, Rades, Thomas & Mullertz, Anette , 29 Jun 2019, In: Advanced Drug Delivery Reviews. 142, p. 35-49 15 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Direct Measurement of Amorphous Solubility
Stukelj, J., Svanback, S., Agopov, M., Löbmann, Korbinian, Strachan, C. J., Rades, Thomas & Yliruusi, J., 4 Jun 2019, In: Analytical Chemistry. 91, 11, p. 7411-7417Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Biorelevant intrinsic dissolution profiling in early drug development: Fundamental, methodological, and industrial aspects
Bergstrom, C. A. S., Box, K., Holm, R., Matthews, W., McAllister, M., Mullertz, Anette , Rades, Thomas, Schaefer, K. J. & Teleki, A., Jun 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 139, p. 101-114Research output: Contribution to journal › Review › Research › peer-review
- Published
Imaging of dehydration in particulate matter using Raman line-focus microscopy
Okeyo, P. O., Ilchenko, O., Slipets, R., Larsen, P. E., Boisen, A., Rades, Thomas & Rantanen, Jukka, 17 May 2019, In: Scientific Reports. 9, 11 p., 7525.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Direct Comparison of Standard Transmission Electron Microscopy and Cryogenic-TEM in Imaging Nanocrystals Inside Liposomes
Li, T., Nowell, C. J., Cipolla, D., Rades, Thomas & Boyd, B. J., Apr 2019, In: Molecular Pharmaceutics. 16, 4, p. 1775-1781Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In situ co-amorphisation in coated tablets – The combination of carvedilol with aspartic acid during immersion in an acidic medium
Petry, I., Löbmann, Korbinian, Grohganz, Holger, Rades, Thomas & Leopold, C. S., 10 Mar 2019, In: International Journal of Pharmaceutics. 558, p. 357-366 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Design of Inhalable Solid Dosage Forms of Budesonide and Theophylline for Pulmonary Combination Therapy
Leng, D., Kissi, E. O., Löbmann, Korbinian, Thanki, K., Fattal, E., Rades, Thomas, Foged, Camilla & Yang, Mingshi, 7 Mar 2019, In: AAPS PharmSciTech. 20, 3, 137.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transformations between Co-Amorphous and Co-Crystal Systems and Their Influence on the Formation and Physical Stability of Co-Amorphous Systems
Wu, W., Wang, Y., Löbmann, Korbinian, Grohganz, Holger & Rades, Thomas, 4 Mar 2019, In: Molecular Pharmaceutics. 16, 3, p. 1294-1304 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Whey proteins as stabilizers in amorphous solid dispersions
Mishra, J., Bohr, A., Rades, Thomas, Grohganz, Holger & Löbmann, Korbinian, 1 Feb 2019, In: European Journal of Pharmaceutical Sciences. 128, p. 144-151 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Process Optimization and Upscaling of Spray-Dried Drug-Amino acid Co-Amorphous Formulations
Kasten, G., Duarte, Í., Paisana, M., Löbmann, Korbinian, Rades, Thomas & Grohganz, Holger, 9 Jan 2019, In: Pharmaceutics. 11, 1, 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterising glass transition temperatures and glass dynamics in mesoporous silica-based amorphous drugs
Kissi, E. O., Ruggiero, M. T., Hempel, N. J., Song, Z., Grohganz, Holger, Rades, Thomas & Löbmann, Korbinian, 1 Jan 2019, In: Physical Chemistry Chemical Physics. 21, 35, p. 19686-19694 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Self-microemulsifying drug delivery system and nanoemulsion for enhancing aqueous miscibility of Alpinia galanga oil
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Influence of Solvent Composition on the Performance of Spray-Dried Co-Amorphous Formulations
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Induction of Cytotoxic T-Lymphocyte Responses Upon Subcutaneous Administration of a Subunit Vaccine Adjuvanted With an Emulsion Containing the Toll-Like Receptor 3 Ligand Poly(I:C)
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Latest publications
Indomethacin-omeprazole as therapeutic hybrids? Salt and co-amorphous systems enhancing physicochemical and pharmacological properties
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The interplay between trehalose and dextran as spray drying precursors for cationic liposomes
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Use of solid thermolytic salts to facilitate microwave-induced in situ amorphization
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