- Published
Formulation optimization, anesthetic activity, skin permeation, and transportation pathway of Alpinia galanga oil SNEDDS in zebrafish (Danio rerio)
Khumpirapang, N., Jørgensen, Louise von Gersdorff, Mullertz, Anette , Rades, Thomas & Okonogi, S., 2021, In: European Journal of Pharmaceutics and Biopharmaceutics. 165, p. 193-202 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Formulation of self-nanoemulsifying drug delivery systems containing monoacyl phosphatidylcholine and Kolliphor® RH40 using experimental design
Tran, T., Rades, Thomas & Mullertz, Anette , 2018, In: Asian Journal of Pharmaceutical Sciences. 13, p. 536-545Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Formulation of co-amorphous systems from naproxen and naproxen sodium and in situ monitoring of physicochemical state changes during dissolution testing by Raman spectroscopy
Ueda, H., Bøtker, Johan Peter, Edinger, M., Löbmann, Korbinian, Grohganz, Holger, Mullertz, Anette , Rades, Thomas & Østergaard, Jesper, 2020, In: International Journal of Pharmaceutics. 587, 119662.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fenofibrate oral absorption from SNEDDS and super-SNEDDS is not significantly affected by lipase inhibition in rats
Michaelsen, M. H., Siqueira Jørgensen, S. D., Abdi, I. M., Wasan, K. M., Rades, Thomas & Mullertz, Anette , 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 142, p. 258-264 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fasted and fed state human duodenal fluids: Characterization, drug solubility, and comparison to simulated fluids and with human bioavailability
Dahlgren, D., Venczel, M., Ridoux, J. P., Skjöld, C., Mullertz, Anette , Holm, R., Augustijns, P., Hellström, P. M. & Lennernäs, H., 2021, In: European Journal of Pharmaceutics and Biopharmaceutics. 163, p. 240-251Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fast and quantitative 2D and 3D orientation mapping using Raman microscopy
Ilchenko, O., Pilgun, Y., Kutsyk, A., Slipets, R., Bachmann, F., Todeschini, M., Okeyo, P. O., Friis Poulsen, H. & Boisen, A., 5 Dec 2019, In: Nature Communications. 10, 9 p., 5555.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fabrication of Mucoadhesive Buccal Films for Local Administration of Ketoprofen and Lidocaine Hydrochloride by Combining Fused Deposition Modeling and Inkjet Printing
Eleftheriadis, G. K., Monou, P. K., Bouropoulos, N., Bøtker, Johan Peter, Rantanen, Jukka, Jacobsen, Jette, Vizirianakis, I. S. & Fatouros, D. G., 2020, In: Journal of Pharmaceutical Sciences. 109, 9, p. 2757-2766Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exploring the utility of the Chasing-rinciple: influence of drug-free SNEDDS composition on solubilization of carvedilol, cinnarizine and R3040 in aqueous suspension
Jorgensen, S. D. S., Rades, Thomas, Mu, Huiling, Graeser, K. & Mullertz, Anette , Jan 2019, In: Acta Pharmaceutica Sinica B. 9, 1, p. 194-201Research output: Contribution to journal › Letter › Research › peer-review
- Published
Exploring the Impact of Intestinal Fluid Components on the Solubility and Supersaturation of Danazol
Madsen, C. M., Plum, J., Hens, B., Augustijns, P., Mullertz, Anette & Rades, Thomas, 2021, In: Journal of Pharmaceutical Sciences. 110, 6, p. 2479-2488 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exploring Porcine Gastric and Intestinal Fluids using Microscopic and Solubility Estimates: Impact of Placebo Self-Emulsifying Drug Delivery System Administration to Inform Bio-Predictive in vitro Tools
Bennett-Lenane, H., Jørgensen, J. R., Koehl, N. J., Henze, L. J., O'Shea, J. P., Mullertz, Anette & Griffin, B. T., 2021, In: European Journal of Pharmaceutical Sciences. 161, 11 p., 105778.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exploration of in vitro drug release testing methods for saquinavir microenvironmental pH modifying buccal films
He, S., Jacobsen, Jette, Nielsen, C. U., Genina, Natalja, Østergaard, Jesper & Mu, Huiling, 2021, In: European Journal of Pharmaceutical Sciences. 163, 10 p., 105867.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ex vivo intestinal perfusion model for investigating mucoadhesion of microcontainers
Dalskov Mosgaard, M., Strindberg, S., Abid, Z., Singh Petersen, R., Højlund Eklund Thamdrup, L., Joukainen Andersen, A., Sylvest Keller, S., Mullertz, Anette , Hagner Nielsen, L. & Boisen, A., 2019, In: International Journal of Pharmaceutics. 570, 118658.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evaluation of self -emulsifying drug delivery systems for oral insulin delivery using an in vitro model simulating the intestinal proteolysis
Liu, J., Hirschberg, C., Fano, M., Mu, Huiling & Mullertz, Anette , 2020, In: European Journal of Pharmaceutical Sciences. 147, 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evaluating side-by-side diffusion models for studying drug supersaturation in an absorptive environment: a case example of fenofibrate and felodipine
Eliasen, Jannik Nicklas, Berthelsen, R., Slot, A. L. & Mullertz, Anette , 2020, In: Journal of Pharmacy and Pharmacology. 72, 3, p. 371-384Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evaluating Oral Drug Delivery Systems: Dissolution Models.
Berthelsen, R., Mullertz, Anette & Rades, Thomas, 2016, Analytical Techniques in the Pharmaceutical Sciences. Springer, p. 753-771Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Evaluating Oral Drug Delivery Systems: Digestion Models.
Berthelsen, R., Sassene, P., Rades, Thomas & Mullertz, Anette , 2016, Analytical Techniques in the Pharmaceutical Sciences. Springer, p. 753-771Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Estimating the Oral Absorption from Self-Nanoemulsifying Drug Delivery Systems Using an In Vitro Lipolysis-Permeation Method
Klitgaard, Mette, Mullertz, Anette & Berthelsen, R., 2021, In: Pharmaceutics. 13, 4, 14 p., 489.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Enhancing Stability and Tooth Bleaching Activity of Carbamide Peroxide by Electrospun Nanofibrous Film
Okonogi, S., Kaewpinta, A., Rades, Thomas, Mullertz, Anette , Yang, Mingshi, Khongkhunthian, S. & Chaijareenont, P., 2020, In: Pharmaceuticals. 13, 11, 20 p., 381.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Elucidating Pathway and Anesthetic Mechanism of Action of Clove Oil Nanoformulations in Fish
Kheawfu, K., Pikulkaew, S., Wellendorph, Petrine, Jørgensen, Louise von Gersdorff, Rades, Thomas, Mullertz, Anette & Okonogi, S., 2022, In: Pharmaceutics. 14, 5, 13 p., 919.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Electrospun α-lactalbumin nanofibers for site-specific and fast-onset delivery of nicotine in the oral cavity: an in vitro, ex vivo and tissue spatial distribution study
Kalouta, Kleopatra, Stie, Mai Bay, Janfelt, Christian, Chronakis, I. S., Jacobsen, Jette, Nielsen, Hanne Mørck & Foderà, Vito, 2020, In: Molecular Pharmaceutics. 17, 11, p. 4189-4200Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of recombinant human gastric lipase and pancreatin during in vitro pediatric gastro-intestinal digestion
Heerup, C., Ebbesen, M. F., Geng, X., Madsen, S. F., Berthelsen, R. & Mullertz, Anette , 2021, In: Food & Function. 12, 7, p. 2938-2949 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of supersaturation on absorption of indomethacin and tadalafil in a single pass intestinal perfusion rat model, in the absence and presence of a precipitation inhibitor
Strindberg, S., Plum, J., Stie, Mai Bay, Christiansen, M. L., Nielsen, L. H., Rades, Thomas & Mullertz, Anette , Jun 2020, In: European Journal of Pharmaceutics and Biopharmaceutics. 151, p. 108-115Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of excipients on encapsulation and release of insulin from spray-dried solid lipid microparticles
Wu, C., van de Weert, Marco, Baldursdottir, S. G., Yang, Mingshi & Mu, Huiling, 25 Oct 2018, In: International Journal of Pharmaceutics. 550, 1-2, p. 439-446Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of composition of simulated intestinal media on the solubility of poorly soluble compounds investigated by design of experiments
Madsen, C. M., Feng, K., Leithead, A., Canfield, N., Jørgensen, S. A., Mullertz, Anette & Rades, Thomas, Jan 2018, In: European Journal of Pharmaceutical Sciences. 111, p. 311-319 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of centrifugation speed on the measured equilibrium solubility of poorly water-soluble compounds in viscous solvents
Liu, X., Mullertz, Anette , Bar-Shalom, Daniel & Berthelsen, R., 2020, In: Journal of Drug Delivery Science and Technology. 59, 8 p., 101853.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of Permeation Enhancers on the Buccal Permeability of Nicotine: Ex vivo Transport Studies Complemented by MALDI MS Imaging
Marxen, E., Jin, L., Jacobsen, Jette, Janfelt, Christian, Hyrup, B. & Nicolazzo, J. A., 21 Feb 2018, In: Pharmaceutical Research. 35, 3, 12 p., 70.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of Drug Loading in Mesoporous Silica on Amorphous Stability and Performance
Bavnhøj, C. G., Knopp, Matthias Manne & Löbmann, Korbinian, 2024, In: Pharmaceutics. 16, 2, 11 p., 163.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Edible solid foams as porous substrates for inkjet-printable pharmaceuticals
Iftimi, L., Edinger, M., Bar-Shalom, Daniel, Rantanen, Jukka & Genina, Natalja, Mar 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 136, p. 38-47Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Drug solubilization during simulated pediatric gastro-intestinal digestion
Kofoed-Djursner, C., Jamil, A., Selen, A., Mullertz, Anette & Berthelsen, R., 2021, In: European Journal of Pharmaceutical Sciences. 162, 8 p., 105828.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Drug Dissolution in Oral Drug Absorption: Workshop Report
Raines, K., Agarwal, P., Augustijns, P., Alayoubi, A., Attia, L., Bauer-Brandl, A., Brandl, M., Chatterjee, P., Chen, H., Yu, Y. C., Coutant, C., Coutinho, A. L., Curran, D., Dressman, J., Ericksen, B., Falade, L., Gao, Y., Gao, Z., Ghosh, D., Ghosh, T. & 26 others, , 2023, In: AAPS Journal. 25, 6, 20 p., 103.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Direct visualizing of paracetamol immediate release tablet disintegration in vivo and in vitro
Fredholt, Freja, Di Meo, C., Sloth, S., Mullertz, Anette & Berthelsen, R., 2022, In: European Journal of Pharmaceutics and Biopharmaceutics. 180, p. 63-70Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Direct Measurement of Lateral Molecular Diffusivity on the Surface of Supersaturated Amorphous Solid Dispersions by Atomic Force Microscopy
Bannow, J., Karl, M., Larsen, P. E., Hwu, E. T. & Rades, Thomas, 2020, In: Molecular Pharmaceutics. 17, 5, p. 1715-1722 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Digestive Enzyme Corona Formed in the Gastrointestinal Tract and Its Impact on Epithelial Cell Uptake of Nanoparticles
Peng, Q., Liu, J., Zhang, T., Zhang, T., Zhang, C. & Mu, Huiling, 8 Apr 2019, In: Biomacromolecules. 20, 4, p. 1789-1797 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Development of gastro-resistant coated probiotic granulates and evaluation of viability and release during simulated upper gastrointestinal transit
Jacobsen, N. M. Y., Nedergaard, H. B., Kock, A., Caglayan, I., Laursen, M. M., Lange, E., Marcial-Coba, M. S., Bar-Shalom, Daniel, Nielsen, Dennis Sandris & Mullertz, Anette , 2021, In: LWT. 144, 9 p., 111174.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Development of a Microgram Scale Video-Microscopic Method to Investigate Dissolution Behavior of Poorly Water-Soluble Drugs
Senniksen, M. B., Christfort, J. F., Marabini, R., Spillum, E., Matthews, W., Da Vià, L., Plum, J., Rades, Thomas & Mullertz, Anette , 2022, In: AAPS PharmSciTech. 23, 6, 173.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Development of Self-Nanoemulsifying Drug Delivery Systems Containing 4-Allylpyrocatechol for Treatment of Oral Infections Caused by Candida albicans
Okonogi, S., Phumat, P., Khongkhunthian, S., Chaijareenont, P., Rades, Thomas & Mullertz, Anette , 2021, In: Pharmaceutics. 13, 2, 16 p., 167.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Development and characterization of clove oil nanoemulsions and self-microemulsifying drug delivery systems
Kheawfu, K., Pikulkaew, S., Rades, Thomas, Mullertz, Anette & Okonogi, S., 2018, In: Journal of Drug Delivery Science and Technology. 46, p. 330-338 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Developing a predictive in vitro dissolution model based on gastrointestinal fluid characterisation in rats
Christfort, J. F., Strindberg, S., Plum, J., Hall-Andersen, J., Janfelt, Christian, Nielsen, L. H. & Mullertz, Anette , 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 142, p. 307-314 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Determining Thermal Conductivity of Small Molecule Amorphous Drugs with Modulated Differential Scanning Calorimetry and Vacuum Molding Sample Preparation
Karl, M., Rantanen, Jukka & Rades, Thomas, 6 Dec 2019, In: Pharmaceutics. 11, 12, 7 p., 670.Research output: Contribution to journal › Journal article › Communication
- Published
Design of a self-unfolding delivery concept for oral administration of macromolecules
Jørgensen, J. R., Thamdrup, L. H. E., Kamguyan, K., Nielsen, L. H., Nielsen, Hanne Mørck, Boisen, A., Rades, Thomas & Mullertz, Anette , 2021, In: Journal of Controlled Release. 329, p. 948-954Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Design and optimization of self-nanoemulsifying drug delivery systems of clove oil for efficacy enhancement in fish anesthesia
Kheawfu, Pikulkaew, Rades, Thomas, Mullertz, Anette , Jørgensen, Louise von Gersdorff & Okonogi, 2021, In: Journal of Drug Delivery Science and Technology. 61, 9 p., 102241.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Design and Optimization of a Nanoparticulate Pore Former as a Multifunctional Coating Excipient for pH Transition-Independent Controlled Release of Weakly Basic Drugs for Oral Drug Delivery
Chang, H. H. R., Chen, K., Lugtu-Pe, J. A., AL-Mousawi, N., Zhang, X., Bar-Shalom, Daniel, Kane, A. & Wu, X. Y., 2023, In: Pharmaceutics. 15, 2, 21 p., 547.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dairy-derived emulsifiers in infant formula show marginal effects on the plasma lipid profile and brain structure in preterm piglets relative to soy lecithin
Henriksen, Nicole Lind, Aasmul-Olsen, Karoline, Venkatasubramanian, R., Nygaard, M. K. E., Sprenger, R. R., Heckmann, A. B., Ostenfeld, M. S., Ejsing, C. S., Eskildsen, S. F., Mullertz, Anette , Sangild, Per Torp, Bering, S. B. & Thymann, Thomas, 2021, In: Nutrients. 13, 3, p. 1-18 18 p., 718.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Current challenges and future perspectives in oral absorption research: An opinion of the UNGAP network
Vinarov, Z., Abrahamsson, B., Artursson, P., Batchelor, H., Berben, P., Bernkop-Schnurch, A., Butler, J., Ceulemans, J., Davies, N., Dupont, D., Flaten, G. E., Fotaki, N., Griffin, B. T., Jannin, V., Keemink, J., Kesisoglou, F., Koziolek, M., Kuentz, M., Mackie, A., Melendez-Martinez, A. J. & 16 others, , 2021, In: Advanced Drug Delivery Reviews. 171, p. 289-331 43 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Convection-Induced vs. Microwave Radiation-Induced in situ Drug Amorphization
Hempel, N., Knopp, Matthias Manne, Berthelsen, R. & Löbmann, Korbinian, 2020, In: Molecules. 25, 5, 7 p., 1068.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Controlling the fractal dimension in self-assembly of terpyridine modified insulin by Fe2+ and Eu3+ to direct in vivo effects
Mishra, N. K., Østergaard, M., Midtgaard, S. R., Strindberg, S. S., Winkler, S., Wu, S., Sørensen, Thomas Just, Hassenkam, Tue, Poulsen, Jens-Christian Navarro, Lo Leggio, Leila, Nielsen, Hanne Mørck, Arleth, Lise, Christensen, Niels Johan, Thulstrup, Peter Waaben & Jensen, Knud Jørgen, 2021, In: Nanoscale. 13, 18, p. 8467–8473 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparison of the liquisolid technique and co-milling for loading of a poorly soluble drug in inorganic porous excipients
Ogadah, C. U., Mrštná, K., Matysová, L., Mullertz, Anette , Rades, Thomas, Niederquell, A., Šklubalová, Z. & Vraníková, B., 2024, In: International Journal of Pharmaceutics. 650, 10 p., 123702.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparison of induction methods for supersaturation: pH shift versus solvent shift
Plum, J., Bavnhoj, C., Palmelund, H., Perez-Alos, L., Mullertz, Anette & Rades, Thomas, 5 Jan 2020, In: International Journal of Pharmaceutics. 573, 8 p., 118862.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparison of induction methods for supersaturation: Amorphous dissolution versus solvent shift
Plum, J., Bavnhoj, C. G., Eliasen, Jannik Nicklas, Rades, Thomas & Mullertz, Anette , 2020, In: European Journal of Pharmaceutics and Biopharmaceutics. 152, p. 35-43 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Combining lipid based drug delivery and amorphous solid dispersions for improved oral drug absorption of a poorly water-soluble drug
Nora, G., Venkatasubramanian, R., Strindberg, S., Siqueira-Jørgensen, S. D., Pagano, L., Romanski, F. S., Swarnakar, N. K., Rades, Thomas & Mullertz, Anette , 2022, In: Journal of Controlled Release. 349, p. 206-212Research output: Contribution to journal › Journal article › Research › peer-review
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Rhamnogalacturonan-I based microcapsules for targeted drug release
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Challenges and trends in apomorphine drug delivery systems for the treatment of Parkinson's disease
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Self-microemulsifying drug delivery system and nanoemulsion for enhancing aqueous miscibility of Alpinia galanga oil
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