Physiological Pharmaceutics

  1. 2020
  2. Published

    Betaxolol Ophthalmic Solution as Alternative Treatment for Patients with Timolol Allergy: A Case Report

    Müllertz, O., Jacobsen, Jette, Thyssen, Jacob Pontoppidan, Horwitz, A. & Kolko, Miriam, 2020, In: Reports — Medical Cases, Images, and Videos. 3, 3, 4 p., 21.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Single particles as resonators for thermomechanical analysis

    Okeyo, P. O., Larsen, P. E., Kissi, E. O., Ajalloueian, F., Rades, Thomas, Rantanen, Jukka & Boisen, A., 2020, In: Nature Communications. 11, 1, 11 p., 1235.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Enhancing Stability and Tooth Bleaching Activity of Carbamide Peroxide by Electrospun Nanofibrous Film

    Okonogi, S., Kaewpinta, A., Rades, Thomas, Mullertz, Anette , Yang, Mingshi, Khongkhunthian, S. & Chaijareenont, P., 2020, In: Pharmaceuticals. 13, 11, 20 p., 381.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Comparison of induction methods for supersaturation: Amorphous dissolution versus solvent shift

    Plum, J., Bavnhoj, C. G., Eliasen, Jannik Nicklas, Rades, Thomas & Mullertz, Anette , 2020, In: European Journal of Pharmaceutics and Biopharmaceutics. 152, p. 35-43 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Comparison of induction methods for supersaturation: pH shift versus solvent shift

    Plum, J., Bavnhoj, C., Palmelund, H., Perez-Alos, L., Mullertz, Anette & Rades, Thomas, 5 Jan 2020, In: International Journal of Pharmaceutics. 573, 8 p., 118862.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Integrated Multi-stakeholder Systems Thinking Strategy: Decision-making with Biopharmaceutics Risk Assessment Roadmap (BioRAM) to Optimize Clinical Performance of Drug Products [incl, correction]

    Selen, A., Mullertz, Anette , Kesisoglou, F., Ho, R. J. Y., Cook, J. A., Dickinson, P. A. & Flanagan, T., 2020, In: AAPS Journal. 22, 5, 20 p., 97.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Poorly soluble drugs

    Siepmann, J., Rades, Thomas, Mullertz, Anette & Loftsson, T., 15 Mar 2020, In: International Journal of Pharmaceutics. 577, 119055.

    Research output: Contribution to journalEditorialResearch

  9. Published

    Swelling of mucoadhesive electrospun chitosan/polyethylene oxide nanofibers facilitates adhesion to the sublingual mucosa

    Stie, Mai Bay, Gätke, J. R., Wan, F., Chronakis, I. S., Jacobsen, Jette & Nielsen, Hanne Mørck, 15 Aug 2020, In: Carbohydrate Polymers. 242, 10 p., 116428.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Waterborne Electrospinning of α-Lactalbumin Generates Tunable and Biocompatible Nanofibers for Drug Delivery

    Stie, Mai Bay, Corezzi, M., Juncos Bombin, A. D., Ajalloueian, F., Attrill, E., Pagliara, S., Jacobsen, Jette, Chronakis, I. S., Nielsen, Hanne Mørck & Foderà, Vito, 2020, In: ACS Applied Nano Materials. 3, 2, p. 1910–1921

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Impact of gastrointestinal physiology on drug absorption in special populations – An UNGAP review

    Stillhart, C., Vucicevic, K., Augustijns, P., Basit, A. W., Batchelor, H., Flanagan, T. R., Gesquiere, I., Greupink, R., Keszthelyi, D., Koskinen, M., Madla, C. M., Matthys, C., Miljus, G., Mooij, M. G., Parrott, N., Ungell, A. -., de Wildt, S. N., Orlu, M., Klein, S. & Mullertz, Anette , 2020, In: European Journal of Pharmaceutical Sciences. 147, 28 p., 105280.

    Research output: Contribution to journalReviewResearchpeer-review

  12. Published

    Effect of supersaturation on absorption of indomethacin and tadalafil in a single pass intestinal perfusion rat model, in the absence and presence of a precipitation inhibitor

    Strindberg, S., Plum, J., Stie, Mai Bay, Christiansen, M. L., Nielsen, L. H., Rades, Thomas & Mullertz, Anette , Jun 2020, In: European Journal of Pharmaceutics and Biopharmaceutics. 151, p. 108-115

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Using in vitro lipolysis and SPECT/CT in vivo imaging to understand oral absorption of fenofibrate from lipid-based drug delivery systems

    Tran, T., Bonlokke, P., Rodriguez-Rodriguez, C., Nosrati, Z., Esquinas, P. L., Borkar, N., Plum, J., Strindberg, S., Karagiozov, S., Rades, Thomas, Mullertz, Anette , Saatchi, K. & Hafeli, U. O., 2020, In: Journal of Controlled Release. 317, p. 375-384

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Characterization of burning mouth syndrome profiles based on response to a local anaesthetic lozenge

    Treldal, C., Petersen, Janne, Mogensen, S., Therkildsen, C., Jacobsen, Jette, Andersen, Ove & Pedersen, Anne Marie Lynge, 2020, In: Oral Diseases. 26, 3, p. 656-669 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Formulation of co-amorphous systems from naproxen and naproxen sodium and in situ monitoring of physicochemical state changes during dissolution testing by Raman spectroscopy

    Ueda, H., Bøtker, Johan Peter, Edinger, M., Löbmann, Korbinian, Grohganz, Holger, Mullertz, Anette , Rades, Thomas & Østergaard, Jesper, 2020, In: International Journal of Pharmaceutics. 587, 119662.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. 2019
  17. Published

    Biodegradable microcontainers-towards real life applications of microfabricated systems for oral drug delivery

    Abid, Z., Strindberg, S., Javed, M. M., Mazzoni, C., Vaut, L., Nielsen, L. H., Gundlach, C., Petersen, R. S., Mullertz, Anette , Boisen, A. & Keller, S. S., 2019, In: Lab on a Chip. 19, 17, p. 2905-2914 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Investigation of Mucoadhesion and Degradation of PCL and PLGA Microcontainers for Oral Drug Delivery

    Abid, Z., Dalskov Mosgaard, M., Manfroni, G., Singh Petersen, R., Hagner Nielsen, L., Mullertz, Anette , Boisen, A. & Sylvest Keller, S., Nov 2019, In: Polymers. 11, 10 p., 1828.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Biorelevant intrinsic dissolution profiling in early drug development: Fundamental, methodological, and industrial aspects

    Bergstrom, C. A. S., Box, K., Holm, R., Matthews, W., McAllister, M., Mullertz, Anette , Rades, Thomas, Schaefer, K. J. & Teleki, A., Jun 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 139, p. 101-114

    Research output: Contribution to journalReviewResearchpeer-review

  20. Published

    Self-emulsifying drug delivery systems (SEDDS) – The splendid comeback of an old technology

    Bernkop-Schnürch, A., Mullertz, Anette & Rades, Thomas, 2019, In: Advanced Drug Delivery Reviews. 142, p. 1-2 2 p.

    Research output: Contribution to journalEditorialResearchpeer-review

  21. Published

    Hvordan udvikler vi bedre medicin til børn?

    Berthelsen, R., 2019, Videnskab.dk, ForskerZonen.

    Research output: Other contributionNet publication - Internet publicationCommunication

  22. Published

    In vitro digestion models to evaluate lipid based drug delivery systems; present status and current trends

    Berthelsen, R., Klitgaard, Mette, Rades, Thomas & Mullertz, Anette , 29 Jun 2019, In: Advanced Drug Delivery Reviews. 142, p. 35-49 15 p.

    Research output: Contribution to journalReviewResearchpeer-review

  23. Published

    Successful oral delivery of poorly water-soluble drugs both depends on the intraluminal behavior of drugs and of appropriate advanced drug delivery systems

    Boyd, B. J., Bergström, C. A. S., Vinarov, Z., Kuentz, M., Brouwers, J., Augustijns, P., Brandl, M., Bernkop-Schnürch, A., Shrestha, N., Préat, V., Mullertz, Anette , Bauer-Brandl, A. & Jannin, V., 2019, In: European Journal of Pharmaceutical Sciences. 137, 27 p., 104967.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    In vitro models for the prediction of in vivo performance of oral dosage forms: Recent progress from partnership through the IMI OrBiTo collaboration

    Butler, J., Hens, B., Vertzoni, M., Brouwers, J., Berben, P., Dressman, J., Andreas, C. J., Schaefer, K. J., Mann, J., McAllister, M., Jamei, M., Kostewicz, E., Kesisoglou, F., Langguth, P., Minekus, M., Mullertz, A., Schilderink, R., Koziolek, M., Jedamzik, P., Weitschies, W. & 2 others, Reppas, C. & Augustijns, P., Mar 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 136, p. 70-83

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Developing a predictive in vitro dissolution model based on gastrointestinal fluid characterisation in rats

    Christfort, J. F., Strindberg, S., Plum, J., Hall-Andersen, J., Janfelt, Christian, Nielsen, L. H. & Mullertz, Anette , 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 142, p. 307-314 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Mucoadhesive Electrospun Patch Delivery of Lidocaine to the Oral Mucosa and Investigation of Spatial Distribution in a Tissue Using MALDI-Mass Spectrometry Imaging

    Clitherow, K. H., Murdoch, C., Spain, S. G., Handler, A. M., Colley, H. E., Stie, Mai Bay, Nielsen, Hanne Mørck, Janfelt, Christian, Hatton, P. V. & Jacobsen, Jette, Sep 2019, In: Molecular Pharmaceutics. 16, 9, p. 3948-3956

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Ex vivo intestinal perfusion model for investigating mucoadhesion of microcontainers

    Dalskov Mosgaard, M., Strindberg, S., Abid, Z., Singh Petersen, R., Højlund Eklund Thamdrup, L., Joukainen Andersen, A., Sylvest Keller, S., Mullertz, Anette , Hagner Nielsen, L. & Boisen, A., 2019, In: International Journal of Pharmaceutics. 570, 118658.

    Research output: Contribution to journalJournal articleResearchpeer-review