Physiological Pharmaceutics

  1. 2022
  2. Published

    Introducing a Novel Biorelevant In Vitro Dissolution Method for the Assessment of Nicotine Release from Oral Tobacco-Derived Nicotine (OTDN) and Snus Products

    Knopp, Matthias Manne, Kiil-Nielsen, N. K., Masser, A. E. & Staaf, M., 2022, In: Separations. 9, 2, 8 p., 52.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Impact of oral gavage technique of drug-containing microcontainers on the gastrointestinal transit and absorption in rats

    Kristensen, M. N., Rades, Thomas, Boisen, A. & Mullertz, Anette , 2022, In: International Journal of Pharmaceutics. 618, 121630.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Impact of Molecular Surface Diffusion on the Physical Stability of Co-Amorphous Systems

    Liu, J., Hwu, E., Bannow, J., Grohganz, Holger & Rades, Thomas, 2022, In: Molecular Pharmaceutics. 19, 4, p. 1183-1190

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    The physicochemical properties of preserved and preservative-free latanoprost eye drops and their impact on human conjunctival goblet cells

    Müllertz, O. A. O., Nagstrup, Anne Hedengran, Mouhammad, Zaynab Ahmad, Freiberg, Josefine, Nagymihály, R., Jacobsen, Jette, Larsen, Susan Weng, Bair, J. A., Utheim, T. P., Dartt, D. A., Heegaard, Steffen, Petrovski, G. & Kolko, Miriam, 2022, In: Acta Ophthalmologica. 100, S267

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  6. Published

    Combining lipid based drug delivery and amorphous solid dispersions for improved oral drug absorption of a poorly water-soluble drug

    Nora, G., Venkatasubramanian, R., Strindberg, S., Siqueira-Jørgensen, S. D., Pagano, L., Romanski, F. S., Swarnakar, N. K., Rades, Thomas & Mullertz, Anette , 2022, In: Journal of Controlled Release. 349, p. 206-212

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Physico-chemical characterization of aspirated and simulated human gastric fluids to study their influence on the intrinsic dissolution rate of cinnarizine

    Pedersen, P. B., Berthelsen, R., Rades, Thomas, Jørgensen, S. A., Vilmann, Peter, Bar-Shalom, Daniel, Baldursdottir, S. & Mullertz, Anette , 2022, In: International Journal of Pharmaceutics. 622, 7 p., 121856.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Development of a Microgram Scale Video-Microscopic Method to Investigate Dissolution Behavior of Poorly Water-Soluble Drugs

    Senniksen, M. B., Christfort, J. F., Marabini, R., Spillum, E., Matthews, W., Da Vià, L., Plum, J., Rades, Thomas & Mullertz, Anette , 2022, In: AAPS PharmSciTech. 23, 6, 173.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Mucoadhesive Electrospun Nanofiber-Based Hybrid System with Controlled and Unidirectional Release of Desmopressin

    Stie, Mai Bay, Gätke, J. R., Chronakis, I. S., Jacobsen, Jette & Nielsen, Hanne Mørck, 2022, In: International Journal of Molecular Sciences. 23, 3, 9 p., 1458.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    UNGAP best practice for improving solubility data quality of orally administered drugs

    Vertzoni, M., Alsenz, J., Augustijns, P., Bauer-Brandl, A., Bergström, C. A. S., Brouwers, J., Mullertz, Anette , Perlovich, G., Saal, C., Sugano, K. & Reppas, C., 1 Jan 2022, In: European Journal of Pharmaceutical Sciences. 168, 21 p., 106043.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Additive Manufacturing of Solid Products for Oral Drug Delivery Using Binder Jetting Three-Dimensional Printing

    Wang, Y., Mullertz, Anette & Rantanen, Jukka, 2022, In: AAPS PharmSciTech. 23, 6, 196.

    Research output: Contribution to journalReviewResearchpeer-review

  12. Published

    Structured approach for designing drug-loaded solid products by binder jetting 3D printing

    Wang, Y., Mullertz, Anette & Rantanen, Jukka, 2022, In: European Journal of Pharmaceutical Sciences. 178, 11 p., 106280.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. 2023
  14. Published

    Biorelevant Dissolution of Dipyridamole and Piroxicam Using an Automated UV/Vis Spectrophotometric and Potentiometric Dissolution Testing Platform

    Berthelsen, R., Larsen, Susan Weng, Mullertz, Anette , Box, K. & Østergaard, Jesper, 2023, In: Dissolution Technologies. 30, 3, p. 144-153

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Design and Optimization of a Nanoparticulate Pore Former as a Multifunctional Coating Excipient for pH Transition-Independent Controlled Release of Weakly Basic Drugs for Oral Drug Delivery

    Chang, H. H. R., Chen, K., Lugtu-Pe, J. A., AL-Mousawi, N., Zhang, X., Bar-Shalom, Daniel, Kane, A. & Wu, X. Y., 2023, In: Pharmaceutics. 15, 2, 21 p., 547.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    In vitro-in vivo relationship for amorphous solid dispersions using a double membrane dissolution-permeation setup

    Jørgensen, J. R., Mohr, W., Rischer, M., Sauer, A., Mistry, S., Rades, Thomas & Mullertz, Anette , 2023, In: European Journal of Pharmaceutics and Biopharmaceutics. 188, p. 26-32

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Stability and intrinsic dissolution of vacuum compression molded amorphous solid dispersions of efavirenz

    Jørgensen, J. R., Mohr, W., Rischer, M., Sauer, A., Mistry, S., Mullertz, Anette & Rades, Thomas, 2023, In: International Journal of Pharmaceutics. 632, 8 p., 122564.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Assessing acute colitis induced by dextran sulfate sodium in rats and its impact on gastrointestinal fluids

    Klitgaard, Mette, Kristensen, M. N., Venkatasubramanian, R., Guerra, Priscila Regina, Jacobsen, Jette, Berthelsen, R., Rades, Thomas & Mullertz, Anette , 2023, In: Drug Delivery and Translational Research. 13, p. 1484–1499

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Amphotericin B and monoacyl-phosphatidylcholine form a stable amorphous complex

    Liu, X., Berthelsen, R., Bar-Shalom, Daniel, Kjellerup Lind, T., Doutch, J. & Mullertz, Anette , 2023, In: International Journal of Pharmaceutics. 633, 10 p., 122601.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Functionalized calcium carbonate (FCC) as a novel carrier to solidify supersaturated self-nanoemulsifying drug delivery systems (super-SNEDDS)

    Merchant, J., Mullertz, Anette , Rades, Thomas & Bannow, J., 2023, In: European Journal of Pharmaceutics and Biopharmaceutics. 193, p. 198-207

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    The Influence of Blonanserin Supersaturation in Liquid and Silica Stabilised Self-Nanoemulsifying Drug Delivery Systems on In Vitro Solubilisation

    Møller, Amalie Lykkemark, Schultz, H. B., Meola, T. R., Joyce, P., Mullertz, Anette & Prestidge, C. A., 2023, In: Pharmaceutics. 15, 1, 14 p., 284.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Drug Dissolution in Oral Drug Absorption: Workshop Report

    Raines, K., Agarwal, P., Augustijns, P., Alayoubi, A., Attia, L., Bauer-Brandl, A., Brandl, M., Chatterjee, P., Chen, H., Yu, Y. C., Coutant, C., Coutinho, A. L., Curran, D., Dressman, J., Ericksen, B., Falade, L., Gao, Y., Gao, Z., Ghosh, D., Ghosh, T. & 26 others, Govada, A., Gray, E., Guo, R., Hammell, D., Hermans, A., Jaini, R., Li, H., Mandula, H., Men, S., Milsmann, J., Moldthan, H., Moody, R., Moseson, D. E., Mullertz, Anette , Patel, R., Paudel, K., Reppas, C., Savkur, R., Schaefer, K., Serajuddin, A., Taylor, L. S., Valapil, R., Wei, K., Weitschies, W., Yamashita, S. & Polli, J. E., 2023, In: AAPS Journal. 25, 6, 20 p., 103.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Moving perfusion culture and live-cell imaging from lab to disc: proof of concept toxicity assay with AI-based image analysis

    Serioli, L., Gruzinskyte, L., Zappalà, G., Hwu, E. T., Laksafoss, T. Z., Jensen, P. L., Demarchi, D., Mullertz, Anette , Boisen, A. & Zór, K., 2023, In: Lab on a Chip. 23, p. 1603-1612

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Mucoadhesive chitosan- and cellulose derivative-based nanofiber-on-foam-on-film system for non-invasive peptide delivery

    Stie, Mai Bay, Öblom, H., Hansen, A. C. N., Jacobsen, Jette, Chronakis, I. S., Rantanen, Jukka, Nielsen, Hanne Mørck & Genina, Natalja, 2023, In: Carbohydrate Polymers. 303, 120429.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Coating of Primary Powder Particles Improves the Quality of Binder Jetting 3D Printed Oral Solid Products

    Wang, Y., Genina, Natalja, Mullertz, Anette & Rantanen, Jukka, 2023, In: Journal of Pharmaceutical Sciences. 112, 2, p. 506-512

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. 2024
  27. Published

    Effect of Drug Loading in Mesoporous Silica on Amorphous Stability and Performance

    Bavnhøj, C. G., Knopp, Matthias Manne & Löbmann, Korbinian, 2024, In: Pharmaceutics. 16, 2, 11 p., 163.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Influence of preparation method and choice of phospholipid on co-amorphization, physical stability, and dissolution behavior of equimolar indomethacin-phospholipid systems: A case study

    Khorami, Keyoomars, Mullertz, Anette & Rades, Thomas, 2024, In: Journal of Drug Delivery Science and Technology. 93, 8 p., 105433.

    Research output: Contribution to journalJournal articleResearchpeer-review

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