Physiological Pharmaceutics

  1. 2020
  2. Published

    Formulation of co-amorphous systems from naproxen and naproxen sodium and in situ monitoring of physicochemical state changes during dissolution testing by Raman spectroscopy

    Ueda, H., Bøtker, Johan Peter, Edinger, M., Löbmann, Korbinian, Grohganz, Holger, Mullertz, Anette , Rades, Thomas & Østergaard, Jesper, 2020, In: International Journal of Pharmaceutics. 587, 119662.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 2021
  4. Published

    Hot punching for loading of biodegradable microcontainers with budesonide-Soluplus film

    Abid, Z., Andreoli, F., Kristensen, M. N., Petersen, R. S., Mullertz, Anette , Boisen, A. & Keller, S. S., 2021, In: Biomedical Microdevices. 23, 11 p., 37.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Exploring Porcine Gastric and Intestinal Fluids using Microscopic and Solubility Estimates: Impact of Placebo Self-Emulsifying Drug Delivery System Administration to Inform Bio-Predictive in vitro Tools

    Bennett-Lenane, H., Jørgensen, J. R., Koehl, N. J., Henze, L. J., O'Shea, J. P., Mullertz, Anette & Griffin, B. T., 2021, In: European Journal of Pharmaceutical Sciences. 161, 11 p., 105778.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    In vitro and in vivo comparison of microcontainers and microspheres for oral drug delivery

    Christfort, J. F., Strindberg, S., Al-khalili, S., Bar-Shalom, Daniel, Boisen, A., Nielsen, L. H. & Mullertz, Anette , 2021, In: International Journal of Pharmaceutics. 600, 9 p., 120516.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Fasted and fed state human duodenal fluids: Characterization, drug solubility, and comparison to simulated fluids and with human bioavailability

    Dahlgren, D., Venczel, M., Ridoux, J. P., Skjöld, C., Mullertz, Anette , Holm, R., Augustijns, P., Hellström, P. M. & Lennernäs, H., 2021, In: European Journal of Pharmaceutics and Biopharmaceutics. 163, p. 240-251

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Predicting Oral Absorption of fenofibrate in Lipid-Based Drug Delivery Systems by Combining In Vitro Lipolysis with the Mucus-PVPA Permeability Model

    Falavigna, M., Klitgaard, Mette, Berthelsen, R., Mullertz, Anette & Flaten, G. E., 2021, In: Journal of Pharmaceutical Sciences. 110, 1, p. 208-216 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Simultaneous assessment of in vitro lipolysis and permeation in the mucus-PVPA model to predict oral absorption of a poorly water soluble drug in SNEDDSs

    Falavigna, M., Brurok, S., Klitgaard, Mette & Flaten, G. E., 2021, In: International Journal of Pharmaceutics. 596, 9 p., 120258.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Towards analyzing the potential of exosomes to deliver microRNA therapeutics

    Giassafaki, L. N., Siqueira, S., Panteris, E., Psatha, K., Chatzopoulou, F., Aivaliotis, M., Tzimagiorgis, G., Mullertz, Anette , Fatouros, D. G. & Vizirianakis, I. S., 2021, In: Journal of Cellular Physiology. 236, 2, p. 1529-1544 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    INFOGEST inter-laboratory recommendations for assaying gastric and pancreatic lipases activities prior to in vitro digestion studies

    Grundy, M. M. L., Abrahamse, E., Almgren, A., Alminger, M., Andres, A., Ariëns, R. M. C., Bastiaan-Net, S., Bourlieu-Lacanal, C., Brodkorb, A., Bronze, M. R., Comi, I., Couëdelo, L., Dupont, D., Durand, A., El, S. N., Grauwet, T., Heerup, C., Heredia, A., Infantes Garcia, M. R., Jungnickel, C. & 26 others, Kłosowska-Chomiczewska, I. E., Létisse, M., Macierzanka, A., Mackie, A. R., McClements, D. J., Menard, O., Meynier, A., Michalski, M. C., Mulet-Cabero, A. I., Mullertz, Anette , Payeras Perelló, F. M., Peinado, I., Robert, M., Secouard, S., Serra, A. T., Silva, S. D., Thomassen, G., Tullberg, C., Undeland, I., Vaysse, C., Vegarud, G. E., Verkempinck, S. H. E., Viau, M., Zahir, M., Zhang, R. & Carrière, F., 2021, In: Journal of Functional Foods. 82, 104497.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Exploration of in vitro drug release testing methods for saquinavir microenvironmental pH modifying buccal films

    He, S., Jacobsen, Jette, Nielsen, C. U., Genina, Natalja, Østergaard, Jesper & Mu, Huiling, 2021, In: European Journal of Pharmaceutical Sciences. 163, 10 p., 105867.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Multi-material 3D printing of programmable and stretchable oromucosal patches for delivery of saquinavir

    He, S., Radeke, C., Jacobsen, Jette, Lind, J. U. & Mu, Huiling, 2021, In: International Journal of Pharmaceutics. 610, 9 p., 121236.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Effects of recombinant human gastric lipase and pancreatin during in vitro pediatric gastro-intestinal digestion

    Heerup, C., Ebbesen, M. F., Geng, X., Madsen, S. F., Berthelsen, R. & Mullertz, Anette , 2021, In: Food & Function. 12, 7, p. 2938-2949 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Microwave-Induced in Situ Drug Amorphization Using a Mixture of Polyethylene Glycol and Polyvinylpyrrolidone

    Hempel, N. J., Knopp, Matthias Manne, Zeitler, J. A., Berthelsen, R. & Löbmann, Korbinian, 2021, In: Journal of Pharmaceutical Sciences. 110, 9, p. 3221-3229

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Studying the impact of the temperature and sorbed water during microwave-induced In Situ amorphization: A case study of celecoxib and polyvinylpyrrolidone

    Hempel, N. J., Knopp, Matthias Manne, Löbmann, Korbinian & Berthelsen, R., 2021, In: Pharmaceutics. 13, 6, 13 p., 886.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    The effect of the molecular weight of polyvinylpyrrolidone and the model drug on laser-induced in situ amorphization

    Hempel, N. J., Merkl, P., Knopp, Matthias Manne, Berthelsen, R., Teleki, A., Hansen, A. K., Sotiriou, G. A. & Löbmann, Korbinian, Jul 2021, In: Molecules. 26, 13, 13 p., 4035.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Utilizing Laser Activation of Photothermal Plasmonic Nanoparticles to Induce On-Demand Drug Amorphization inside a Tablet

    Hempel, N. J., Merkl, P., Asad, S., Knopp, M. M., Berthelsen, R., Bergström, C. A. S., Teleki, A., Sotiriou, G. A. & Löbmann, Korbinian, 2021, In: Molecular Pharmaceutics. 18, 6, p. 2254–2262

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    The Influence of Drug-Polymer Solubility on Laser-Induced In Situ Drug Amorphization Using Photothermal Plasmonic Nanoparticles

    Hempel, N., Merkl, P., Knopp, Matthias Manne, Berthelsen, R., Teleki, A., Sotiriou, G. A. & Löbmann, Korbinian, 2021, In: Pharmaceutics. 13, 6, 12 p., 917.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    The Influence of Temperature and Viscosity of Polyethylene Glycol on the Rate of Microwave-Induced In Situ Amorphization of Celecoxib

    Hempel, N., Dao, T., Knopp, Matthias Manne, Berthelsen, R. & Löbmann, Korbinian, 2021, In: Molecules. 26, 1, 8 p., 110.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    The Use of Glycerol as an Enabling Excipient for Microwave-Induced In Situ Drug Amorphization

    Hempel, N., Morsch, F., Knopp, Matthias Manne, Berthelsen, R. & Löbmann, Korbinian, 2021, In: Journal of Pharmaceutical Sciences. 110, 1, p. 155-163 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Dairy-derived emulsifiers in infant formula show marginal effects on the plasma lipid profile and brain structure in preterm piglets relative to soy lecithin

    Henriksen, Nicole Lind, Aasmul-Olsen, Karoline, Venkatasubramanian, R., Nygaard, M. K. E., Sprenger, R. R., Heckmann, A. B., Ostenfeld, M. S., Ejsing, C. S., Eskildsen, S. F., Mullertz, Anette , Sangild, Per Torp, Bering, S. B. & Thymann, Thomas, 2021, In: Nutrients. 13, 3, p. 1-18 18 p., 718.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Microwave induced in situ amorphisation facilitated by crystalline hydrates

    Holm, T. P., Knopp, M. M., Löbmann, Korbinian & Berthelsen, R., 2021, In: European Journal of Pharmaceutical Sciences. 163, 9 p., 105858.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Development of gastro-resistant coated probiotic granulates and evaluation of viability and release during simulated upper gastrointestinal transit

    Jacobsen, N. M. Y., Nedergaard, H. B., Kock, A., Caglayan, I., Laursen, M. M., Lange, E., Marcial-Coba, M. S., Bar-Shalom, Daniel, Nielsen, Dennis Sandris & Mullertz, Anette , 2021, In: LWT. 144, 9 p., 111174.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Design of a self-unfolding delivery concept for oral administration of macromolecules

    Jørgensen, J. R., Thamdrup, L. H. E., Kamguyan, K., Nielsen, L. H., Nielsen, Hanne Mørck, Boisen, A., Rades, Thomas & Mullertz, Anette , 2021, In: Journal of Controlled Release. 329, p. 948-954

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Design and optimization of self-nanoemulsifying drug delivery systems of clove oil for efficacy enhancement in fish anesthesia

    Kheawfu, Pikulkaew, Rades, Thomas, Mullertz, Anette , Jørgensen, Louise von Gersdorff & Okonogi, 2021, In: Journal of Drug Delivery Science and Technology. 61, 9 p., 102241.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Formulation optimization, anesthetic activity, skin permeation, and transportation pathway of Alpinia galanga oil SNEDDS in zebrafish (Danio rerio)

    Khumpirapang, N., Jørgensen, Louise von Gersdorff, Mullertz, Anette , Rades, Thomas & Okonogi, S., 2021, In: European Journal of Pharmaceutics and Biopharmaceutics. 165, p. 193-202 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review