Sertraline inhibits the transport of PAT1 substrates in vivo and in vitro

Research output: Contribution to journalJournal articleResearchpeer-review

  • Carsten Uhd Nielsen
  • Sidsel Balsgaard Frølund
  • S Abdulhadi
  • H Sari
  • L Langthaler
  • Mark Klitgaard Nøhr
  • M A Kall
  • Larsen, Birger Brodin
  • R Holm
Intestinal nutrient transporters may mediate the uptake of drugs. The aim of this study was to investigate whether sertraline interacts with the intestinal proton-coupled amino acid transporter 1 PAT1 (SLC36A1).
Original languageEnglish
JournalBritish Journal of Pharmacology
Volume170
Issue number5
Pages (from-to)1041-52
Number of pages12
ISSN0007-1188
DOIs
Publication statusPublished - Nov 2013

ID: 62538336