Transport characteristics of L-carnosine and the anticancer derivative 4-toluenesulfonylureido-carnosine in a human epithelial cell line
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Transport characteristics of L-carnosine and the anticancer derivative 4-toluenesulfonylureido-carnosine in a human epithelial cell line. / Nielsen, Carsten Uhd; Supuran, Claudiu T; Scozzafava, Andrea; Frokjaer, Sven; Steffansen, Bente; Brodin, Birger.
In: Pharmaceutical Research, Vol. 19, No. 9, 2002, p. 1337-44.Research output: Contribution to journal › Journal article › peer-review
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TY - JOUR
T1 - Transport characteristics of L-carnosine and the anticancer derivative 4-toluenesulfonylureido-carnosine in a human epithelial cell line
AU - Nielsen, Carsten Uhd
AU - Supuran, Claudiu T
AU - Scozzafava, Andrea
AU - Frokjaer, Sven
AU - Steffansen, Bente
AU - Brodin, Birger
PY - 2002
Y1 - 2002
N2 - The aim of the present study was to evaluate whether the transepithelial transport of the anticancer compound 4-toluenesulfonylureido-carnosine (Ts-carnosine) and the dipeptide moiety L-carnosine was due to a hPepT1 carrier-mediated flux.
AB - The aim of the present study was to evaluate whether the transepithelial transport of the anticancer compound 4-toluenesulfonylureido-carnosine (Ts-carnosine) and the dipeptide moiety L-carnosine was due to a hPepT1 carrier-mediated flux.
KW - Antineoplastic Agents
KW - Biological Transport
KW - Caco-2 Cells
KW - Carnosine
KW - Epithelial Cells
KW - Humans
KW - Intestinal Mucosa
KW - Tosyl Compounds
M3 - Journal article
C2 - 12403071
VL - 19
SP - 1337
EP - 1344
JO - Pharmaceutical Research
JF - Pharmaceutical Research
SN - 0724-8741
IS - 9
ER -
ID: 37899651