The structural shift of a DNA template between a hairpin and a dimer tunes the emission color of DNA-templated AgNCs
Research output: Contribution to journal › Journal article › Research › peer-review
Standard
The structural shift of a DNA template between a hairpin and a dimer tunes the emission color of DNA-templated AgNCs. / Shah, Pratik; Choi, Suk Won; Nagda, Riddhi; Geczy, Reka; Cho, Seok Keun; Bhang, Yong Joo; Kim, Tae-Hwan; Song, Tae Yang; Lee, Phil Hyu; Kang, Ju-Hee; Thulstrup, Peter Waaben; Bjerrum, Morten Jannik; Jung, Il Lae; Yang, Seong Wook.
In: Nanoscale, Vol. 10, No. 44, 2018, p. 20717-20722.Research output: Contribution to journal › Journal article › Research › peer-review
Harvard
APA
Vancouver
Author
Bibtex
}
RIS
TY - JOUR
T1 - The structural shift of a DNA template between a hairpin and a dimer tunes the emission color of DNA-templated AgNCs
AU - Shah, Pratik
AU - Choi, Suk Won
AU - Nagda, Riddhi
AU - Geczy, Reka
AU - Cho, Seok Keun
AU - Bhang, Yong Joo
AU - Kim, Tae-Hwan
AU - Song, Tae Yang
AU - Lee, Phil Hyu
AU - Kang, Ju-Hee
AU - Thulstrup, Peter Waaben
AU - Bjerrum, Morten Jannik
AU - Jung, Il Lae
AU - Yang, Seong Wook
PY - 2018
Y1 - 2018
N2 - The scaffolding DNA sequence and the size of silver nanoclusters (AgNCs), confined in a DNA template are the key parameters in determining the fluorescent properties of DNA-stabilized silver nanoclusters (DNA/AgNCs). In addition, we suggest here that the structural shift of a DNA hairpin-dimer is as important as the DNA sequence in determining the emission wavelength of DNA/AgNCs. Furthermore, we show that the structural shift post AgNC formation can be triggered by incubation time and pre-AgNC formation under salt conditions. As an important factor in predicting the emission properties of DNA/AgNCs, the modulation of DNA secondary structures with either sequence changes or ionic conditions can be applied for the dual-color detection system of a target molecule. Particularly, the dual-color detection method may increase the reliability of DNA/AgNC sensors for miRNAs.
AB - The scaffolding DNA sequence and the size of silver nanoclusters (AgNCs), confined in a DNA template are the key parameters in determining the fluorescent properties of DNA-stabilized silver nanoclusters (DNA/AgNCs). In addition, we suggest here that the structural shift of a DNA hairpin-dimer is as important as the DNA sequence in determining the emission wavelength of DNA/AgNCs. Furthermore, we show that the structural shift post AgNC formation can be triggered by incubation time and pre-AgNC formation under salt conditions. As an important factor in predicting the emission properties of DNA/AgNCs, the modulation of DNA secondary structures with either sequence changes or ionic conditions can be applied for the dual-color detection system of a target molecule. Particularly, the dual-color detection method may increase the reliability of DNA/AgNC sensors for miRNAs.
U2 - 10.1039/c8nr06186f
DO - 10.1039/c8nr06186f
M3 - Journal article
C2 - 30398269
VL - 10
SP - 20717
EP - 20722
JO - Nanoscale
JF - Nanoscale
SN - 2040-3364
IS - 44
ER -
ID: 209470306