Solid-state analysis for pharmaceuticals: Pathways to feasible and meaningful analysis
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Solid-state analysis for pharmaceuticals : Pathways to feasible and meaningful analysis. / Rantanen, Jukka; Rades, Thomas; Strachan, Clare.
In: Journal of Pharmaceutical and Biomedical Analysis, Vol. 236, 115649, 2023.Research output: Contribution to journal › Review › Research › peer-review
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TY - JOUR
T1 - Solid-state analysis for pharmaceuticals
T2 - Pathways to feasible and meaningful analysis
AU - Rantanen, Jukka
AU - Rades, Thomas
AU - Strachan, Clare
N1 - Funding Information: This work has been supported by NordForsk (Oslo, Norway) - Nordic University Hub project Nordic POP (Patient Oriented Products; project number 85352 ). Publisher Copyright: © 2023 The Authors
PY - 2023
Y1 - 2023
N2 - The solid state of matter is the preferred starting point for designing a pharmaceutical product. This is driven by both patient preferences and the relative ease of supplying a solid pharmaceutical product with desired quality and performance. Solid form diversity is increasingly prevalent as a crucial element in designing these products, which underpins the importance of solid-state analytical methods. This paper provides a critical analysis of challenges related to solid-state analytics, as well as considerations and suggestions for feasible and meaningful pharmaceutical analysis.
AB - The solid state of matter is the preferred starting point for designing a pharmaceutical product. This is driven by both patient preferences and the relative ease of supplying a solid pharmaceutical product with desired quality and performance. Solid form diversity is increasingly prevalent as a crucial element in designing these products, which underpins the importance of solid-state analytical methods. This paper provides a critical analysis of challenges related to solid-state analytics, as well as considerations and suggestions for feasible and meaningful pharmaceutical analysis.
KW - Analytical techniques
KW - Dosage form
KW - Process analytics
KW - Product performance
KW - Sample preparation
KW - Solid-state properties
U2 - 10.1016/j.jpba.2023.115649
DO - 10.1016/j.jpba.2023.115649
M3 - Review
C2 - 37657177
AN - SCOPUS:85168993780
VL - 236
JO - Journal of Pharmaceutical and Biomedical Analysis
JF - Journal of Pharmaceutical and Biomedical Analysis
SN - 0731-7085
M1 - 115649
ER -
ID: 366305159