In silico product design of pharmaceuticals

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Johan Boetker, Dhara Raijada, Johanna Aho, Milad Khorasani, Søren Vinter Søgaard, Lærke Arnfast, Adam Bohr, Magnus Edinger, Jorrit Water, Jukka Rantanen

Abstract The increasing demand for personalized medicine necessitates the production of easily customizable dosage forms. As the number of possible dosage forms may scale towards infinity, their uniqueness require a versatile production platform and numerical simulation in order to be manufactured efficiently. A mathematical description of these systems is the only feasible approach to manage such diverse properties of different products. However, experimental verification is still essential for evaluation of processability and related concomitant phenomena, such as possible solid state changes that may occur during production and storage.
Original languageDanish
JournalAsian Journal of Pharmaceutical Sciences
Volume11
Issue number4
Pages (from-to)492–499
Number of pages8
ISSN1818-0876
DOIs
Publication statusPublished - 2016

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