TY - JOUR

T1 - Electromembrane extraction of high level substances

T2 - A novel approach for selective recovery of templates in molecular imprinting

AU - Lin, Bin

AU - Wan, Libin

AU - Sun, Xiaojie

AU - Huang, Chuixiu

AU - Pedersen-Bjergaard, Stig

AU - Shen, Xiantao

PY - 2018

Y1 - 2018

N2 - Numerous efficient extraction methods have been developed for material recovery. However, most of these methods lack selectivity. Recently, we reported electromembrane extraction (EME) as a green, efficient and selective technology for simultaneous extraction and purification of trace targets for sample preparation purpose. Accordingly, EME could be a promising technique on resource conservation, for example, selective recovery of templates with high purity in molecular imprinting. In this work, we first investigated the potential of EME with different configurations for selective recovery of targets at high level (≥ 1000 μg mL−1). A semi-dynamic EME system was applied for EME of a basic template (propranolol) from molecularly imprinted samples prepared by precipitation polymerization and bulk polymerization, and the recoveries were 61% and 55%, respectively. The selectivity of EME for template recovery from real samples was confirmed by UV–vis, HPLC-UV and MS measurements. Moreover, the universality of EME for template recovery was verified by efficient extraction of an acidic template (probenecid). Definitely, EME could be used to solve the historic issue of template recovery in molecular imprinting, and shows great potential for selective extraction of ionizable compounds from complex samples in a single step.

AB - Numerous efficient extraction methods have been developed for material recovery. However, most of these methods lack selectivity. Recently, we reported electromembrane extraction (EME) as a green, efficient and selective technology for simultaneous extraction and purification of trace targets for sample preparation purpose. Accordingly, EME could be a promising technique on resource conservation, for example, selective recovery of templates with high purity in molecular imprinting. In this work, we first investigated the potential of EME with different configurations for selective recovery of targets at high level (≥ 1000 μg mL−1). A semi-dynamic EME system was applied for EME of a basic template (propranolol) from molecularly imprinted samples prepared by precipitation polymerization and bulk polymerization, and the recoveries were 61% and 55%, respectively. The selectivity of EME for template recovery from real samples was confirmed by UV–vis, HPLC-UV and MS measurements. Moreover, the universality of EME for template recovery was verified by efficient extraction of an acidic template (probenecid). Definitely, EME could be used to solve the historic issue of template recovery in molecular imprinting, and shows great potential for selective extraction of ionizable compounds from complex samples in a single step.

KW - Electromembrane extraction

KW - High level substances

KW - Molecular imprinting

KW - Selectivity

KW - Template recovery

U2 - 10.1016/j.memsci.2018.09.056

DO - 10.1016/j.memsci.2018.09.056

M3 - Journal article

AN - SCOPUS:85054003138

VL - 568

SP - 30

EP - 39

JO - Journal of Membrane Science

JF - Journal of Membrane Science

SN - 0376-7388

ER -