Electrical contacts for ce-ms interfaces based on generating cracks/fractures along the capillary
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Electrical contacts for ce-ms interfaces based on generating cracks/fractures along the capillary. / Petersen, Nickolaj J.
2015, Patent.Research output: Other contribution › Research
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TY - GEN
T1 - Electrical contacts for ce-ms interfaces based on generating cracks/fractures along the capillary
AU - Petersen, Nickolaj J.
PY - 2015
Y1 - 2015
N2 - There is provided an electrical contact for a CE-MS interface. The contact is obtained by establishing a fracture or crack less than 2 micrometer in dimension(width) close to the spray tip. A reservoir is provided in liquid contact with the crack/fracture and filled with a reservoir liquid, and an electrode is placed in contact with the reservoir liquid. Several cracks/fractures can be created with their respective reservoirs. Beside providing the electrical contact for the electrophoretic separation and/or electrospray ionization, the crack/fracture can be used for electrokinetically introducing reagents or analytes into the capillary, for example, for providing deuterium for hydrogen-deuterium exchange (HDX) experiments.
AB - There is provided an electrical contact for a CE-MS interface. The contact is obtained by establishing a fracture or crack less than 2 micrometer in dimension(width) close to the spray tip. A reservoir is provided in liquid contact with the crack/fracture and filled with a reservoir liquid, and an electrode is placed in contact with the reservoir liquid. Several cracks/fractures can be created with their respective reservoirs. Beside providing the electrical contact for the electrophoretic separation and/or electrospray ionization, the crack/fracture can be used for electrokinetically introducing reagents or analytes into the capillary, for example, for providing deuterium for hydrogen-deuterium exchange (HDX) experiments.
UR - https://www.google.com/patents/WO2015197072A1?cl=en
M3 - Other contribution
ER -
ID: 279143237