Discovery of a cyclic 6 + 6 hexamer of d-biotin and formaldehyde

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Discovery of a cyclic 6 + 6 hexamer of d-biotin and formaldehyde. / Lisbjerg, Micke; Jessen, Bo M.; Rasmussen, Brian; Nielsen, Bjarne Enrico; Madsen, Anders Østergaard; Pittelkow, Michael.

In: Chemical Science, Vol. 5, No. 7, 2014, p. 2647-2650.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Lisbjerg, M, Jessen, BM, Rasmussen, B, Nielsen, BE, Madsen, AØ & Pittelkow, M 2014, 'Discovery of a cyclic 6 + 6 hexamer of d-biotin and formaldehyde', Chemical Science, vol. 5, no. 7, pp. 2647-2650. https://doi.org/10.1039/c4sc00990h

APA

Lisbjerg, M., Jessen, B. M., Rasmussen, B., Nielsen, B. E., Madsen, A. Ø., & Pittelkow, M. (2014). Discovery of a cyclic 6 + 6 hexamer of d-biotin and formaldehyde. Chemical Science, 5(7), 2647-2650. https://doi.org/10.1039/c4sc00990h

Vancouver

Lisbjerg M, Jessen BM, Rasmussen B, Nielsen BE, Madsen AØ, Pittelkow M. Discovery of a cyclic 6 + 6 hexamer of d-biotin and formaldehyde. Chemical Science. 2014;5(7):2647-2650. https://doi.org/10.1039/c4sc00990h

Author

Lisbjerg, Micke ; Jessen, Bo M. ; Rasmussen, Brian ; Nielsen, Bjarne Enrico ; Madsen, Anders Østergaard ; Pittelkow, Michael. / Discovery of a cyclic 6 + 6 hexamer of d-biotin and formaldehyde. In: Chemical Science. 2014 ; Vol. 5, No. 7. pp. 2647-2650.

Bibtex

@article{eb0d8c30e59549fca8a69599d9fa1f73,
title = "Discovery of a cyclic 6 + 6 hexamer of d-biotin and formaldehyde",
abstract = "The discovery of receptors using templated synthesis enables the selection of strong receptors from complex mixtures. In this contribution we describe a study of the condensation of d-biotin and formaldehyde in acidic water. We have discovered that halide anions template the formation of a single isomer of a 6 + 6 macrocycle. The macrocycle (biotin[6]uril) is water-soluble, chiral and binds halide anions (iodide, bromide and chloride) with selectivity for iodide in water, and it can be isolated on a gram scale in a one-pot reaction in 63% yield.",
author = "Micke Lisbjerg and Jessen, {Bo M.} and Brian Rasmussen and Nielsen, {Bjarne Enrico} and Madsen, {Anders {\O}stergaard} and Michael Pittelkow",
year = "2014",
doi = "10.1039/c4sc00990h",
language = "English",
volume = "5",
pages = "2647--2650",
journal = "Chemical Science",
issn = "2041-6520",
publisher = "Royal Society of Chemistry",
number = "7",

}

RIS

TY - JOUR

T1 - Discovery of a cyclic 6 + 6 hexamer of d-biotin and formaldehyde

AU - Lisbjerg, Micke

AU - Jessen, Bo M.

AU - Rasmussen, Brian

AU - Nielsen, Bjarne Enrico

AU - Madsen, Anders Østergaard

AU - Pittelkow, Michael

PY - 2014

Y1 - 2014

N2 - The discovery of receptors using templated synthesis enables the selection of strong receptors from complex mixtures. In this contribution we describe a study of the condensation of d-biotin and formaldehyde in acidic water. We have discovered that halide anions template the formation of a single isomer of a 6 + 6 macrocycle. The macrocycle (biotin[6]uril) is water-soluble, chiral and binds halide anions (iodide, bromide and chloride) with selectivity for iodide in water, and it can be isolated on a gram scale in a one-pot reaction in 63% yield.

AB - The discovery of receptors using templated synthesis enables the selection of strong receptors from complex mixtures. In this contribution we describe a study of the condensation of d-biotin and formaldehyde in acidic water. We have discovered that halide anions template the formation of a single isomer of a 6 + 6 macrocycle. The macrocycle (biotin[6]uril) is water-soluble, chiral and binds halide anions (iodide, bromide and chloride) with selectivity for iodide in water, and it can be isolated on a gram scale in a one-pot reaction in 63% yield.

U2 - 10.1039/c4sc00990h

DO - 10.1039/c4sc00990h

M3 - Journal article

AN - SCOPUS:84901856569

VL - 5

SP - 2647

EP - 2650

JO - Chemical Science

JF - Chemical Science

SN - 2041-6520

IS - 7

ER -

ID: 130988244