Aluminium and nickel in human albumin solutions

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Aluminium and nickel in human albumin solutions. / Gammelgaard, Bente; Sandberg, E.

In: Journal of Trace Elements and Electrolytes in Health and Disease, Vol. 3, No. 1, 1989, p. 39-42.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Gammelgaard, B & Sandberg, E 1989, 'Aluminium and nickel in human albumin solutions', Journal of Trace Elements and Electrolytes in Health and Disease, vol. 3, no. 1, pp. 39-42.

APA

Gammelgaard, B., & Sandberg, E. (1989). Aluminium and nickel in human albumin solutions. Journal of Trace Elements and Electrolytes in Health and Disease, 3(1), 39-42.

Vancouver

Gammelgaard B, Sandberg E. Aluminium and nickel in human albumin solutions. Journal of Trace Elements and Electrolytes in Health and Disease. 1989;3(1):39-42.

Author

Gammelgaard, Bente ; Sandberg, E. / Aluminium and nickel in human albumin solutions. In: Journal of Trace Elements and Electrolytes in Health and Disease. 1989 ; Vol. 3, No. 1. pp. 39-42.

Bibtex

@article{0e0a9f8a33504e61b8b3b21402380f7c,
title = "Aluminium and nickel in human albumin solutions",
abstract = "Five different brands of commercially available human albumin solutions for infusion were analysed for their aluminium and nickel contents by atomic absorption spectrometry. The aluminium concentrations ranged from 12 micrograms/l to 1109 micrograms/l and the nickel concentrations ranged from 17 micrograms/l to 77 micrograms/l. Examination of the aluminium and nickel contents of the constituents for the production of one brand showed too low levels to explain the final contamination of the product. By following the aluminium and nickel concentrations of the same brand during the production of a batch of albumin solution, filtration was shown to contribute to contamination, although the largest increase in aluminium as well as nickel concentrations appeared during the bulk concentrating process. To avoid health risks to certain patients, regulations should be established requiring aluminium and nickel contamination to be as low as possible.",
keywords = "Albumins, Aluminum, Drug Contamination, Hemodialysis Solutions, Humans, Nickel",
author = "Bente Gammelgaard and E Sandberg",
year = "1989",
language = "English",
volume = "3",
pages = "39--42",
journal = "Journal of Trace Elements and Electrolytes in Health and Disease",
issn = "0931-2838",
publisher = "Elsevier",
number = "1",

}

RIS

TY - JOUR

T1 - Aluminium and nickel in human albumin solutions

AU - Gammelgaard, Bente

AU - Sandberg, E

PY - 1989

Y1 - 1989

N2 - Five different brands of commercially available human albumin solutions for infusion were analysed for their aluminium and nickel contents by atomic absorption spectrometry. The aluminium concentrations ranged from 12 micrograms/l to 1109 micrograms/l and the nickel concentrations ranged from 17 micrograms/l to 77 micrograms/l. Examination of the aluminium and nickel contents of the constituents for the production of one brand showed too low levels to explain the final contamination of the product. By following the aluminium and nickel concentrations of the same brand during the production of a batch of albumin solution, filtration was shown to contribute to contamination, although the largest increase in aluminium as well as nickel concentrations appeared during the bulk concentrating process. To avoid health risks to certain patients, regulations should be established requiring aluminium and nickel contamination to be as low as possible.

AB - Five different brands of commercially available human albumin solutions for infusion were analysed for their aluminium and nickel contents by atomic absorption spectrometry. The aluminium concentrations ranged from 12 micrograms/l to 1109 micrograms/l and the nickel concentrations ranged from 17 micrograms/l to 77 micrograms/l. Examination of the aluminium and nickel contents of the constituents for the production of one brand showed too low levels to explain the final contamination of the product. By following the aluminium and nickel concentrations of the same brand during the production of a batch of albumin solution, filtration was shown to contribute to contamination, although the largest increase in aluminium as well as nickel concentrations appeared during the bulk concentrating process. To avoid health risks to certain patients, regulations should be established requiring aluminium and nickel contamination to be as low as possible.

KW - Albumins

KW - Aluminum

KW - Drug Contamination

KW - Hemodialysis Solutions

KW - Humans

KW - Nickel

M3 - Journal article

C2 - 2535318

VL - 3

SP - 39

EP - 42

JO - Journal of Trace Elements and Electrolytes in Health and Disease

JF - Journal of Trace Elements and Electrolytes in Health and Disease

SN - 0931-2838

IS - 1

ER -

ID: 44053170