Thomas Rades
Professor
Pharmaceuticals, processes and products
Universitetsparken 2
2100 København Ø
- Published
A Promising New Method to Estimate Drug-Polymer Solubility at Room Temperature
Knopp, Matthias Manne, Gannon, N., Porsch, I., Rask, M. B., Olesen, N. E., Langguth, P., Holm, R. & Rades, Thomas, Sep 2016, In: Journal of Pharmaceutical Sciences. 105, 9, p. 2621-2624 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Anhydrate to hydrate solid-state transformations of carbamazepine and nitrofurantoin in biorelevant media studied in situ using time-resolved synchrotron X-ray diffraction
Bøtker, Johan Peter, Rantanen, Jukka, Arnfast, L., Doreth, M., Raijada, D. K., Löbmann, Korbinian, Madsen, C. M., Khan, J., Rades, Thomas, Mullertz, Anette , Hawley, A., Thomas, D. & Boyd, B. J., Mar 2016, In: European Journal of Pharmaceutics and Biopharmaceutics. 100, p. 119-127 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Comparison of lipases for in vitro models of gastric digestion: lipolysis using two infant formulas as model substrates
Sassene, P. J., Fanø, M., Mu, Huiling, Rades, Thomas, Aquistapace, S., Schmitt, B., Cruz-Hernandez, C., Wooster, T. J. & Mullertz, Anette , 14 Sep 2016, In: Food & Function. 7, 9, p. 3989-3998 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Development of a screening method for co-amorphous formulations of drugs and amino acids
Kasten, G., Grohganz, Holger, Rades, Thomas & Löbmann, Korbinian, Dec 2016, In: European Journal of Pharmaceutical Sciences. 95, p. 28-35 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effect of polymer type and drug dose on the in vitro and in vivo behavior of amorphous solid dispersions
Knopp, Matthias Manne, Chourak, N., Khan, F., Wendelboe, J., Langguth, P., Rades, Thomas & Holm, R., Aug 2016, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 105, p. 106-14 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Erratum: Formation of drug nanocrystals under nanoconfinement afforded by liposomes (RSC Adv. (2016) 6 (6223-6233))
Cipolla, D., Wu, H., Salentinig, S., Boyd, Ben, Rades, Thomas, Vanhecke, D., Petri-Fink, A., Rothen-Rutishauser, B., Eastman, S., Redelmeier, T., Gonda, I. & Chan, H. K., 2016, In: RSC Advances. 6, 15, p. 12123 1 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
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Erratum: Formulation and characterization of self-nanoemulsifying drug delivery systems containing monoacyl phosphatidylcholine (International Journal of Pharmaceutics (2016) 502:1-2 (151-160) DOI: 10.1016/j.ijpharm.2016.02.026 )
Tran, T., Xi, X., Rades, Thomas & Mullertz, Anette , 30 Jun 2016, In: International Journal of Pharmaceutics. 507, 1-2, p. 109 1 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Evaluating Oral Drug Delivery Systems: Digestion Models.
Berthelsen, R., Sassene, P., Rades, Thomas & Mullertz, Anette , 2016, Analytical Techniques in the Pharmaceutical Sciences. Springer, p. 753-771Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Evaluating Oral Drug Delivery Systems: Dissolution Models.
Berthelsen, R., Mullertz, Anette & Rades, Thomas, 2016, Analytical Techniques in the Pharmaceutical Sciences. Springer, p. 753-771Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Formation of drug nanocrystals under nanoconfinement afforded by liposomes
Cipolla, D., Wu, H., Salentinig, S., Boyd, B., Rades, Thomas, Vanhecke, D., Petri-Fink, A., Rothin-Rutishauser, B., Eastman, S., Redelmeier, T., Gonda, I. & Chan, H., 2016, In: RSC Advances. 6, 8, p. 6223-6233 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Formulation and characterization of self-nanoemulsifying drug delivery systems containing monoacyl phosphatidylcholine
Tran, T., Xi, X., Rades, Thomas & Mullertz, Anette , 11 Apr 2016, In: International Journal of Pharmaceutics. 502, 1-2, p. 151-60 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glass forming ability of amorphous drugs investigated by continuous cooling- and isothermal transformation
Blaabjerg, L. I., Lindenberg, E., Löbmann, Korbinian, Grohganz, Holger & Rades, Thomas, 2016, In: Molecular Pharmaceutics. 13, 9, p. 3318-3325 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Glass solution formation in water - In situ amorphization of naproxen and ibuprofen with Eudragit® E PO
Doreth, M., Löbmann, Korbinian, Grohganz, Holger, Holm, R., Lopez De Diego, H., Rades, Thomas & Priemel, P. A., 1 Feb 2016, In: Journal of Drug Delivery Science and Technology. 34, p. 32–40 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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INFLUENCE OF THE COOLING RATE AND THE BLEND RATIO ON THE PHYSICAL STABILTIY OF CO-AMORPHOUS NAPROXEN/INDOMETHACIN
Beyer, A., Grohganz, Holger, Löbmann, Korbinian, Rades, Thomas & Leopold, C. S., 13 Oct 2016, In: European Journal of Pharmaceutics and Biopharmaceutics. 109, p. 140-148 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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In Situ Lipolysis and Synchrotron Small-Angle X-ray Scattering for the Direct Determination of the Precipitation and Solid-State Form of a Poorly Water-Soluble Drug During Digestion of a Lipid-Based Formulation
Khan, J., Hawley, A., Rades, Thomas & Boyd, B. J., Sep 2016, In: Journal of Pharmaceutical Sciences. 105, 9, p. 2631-2639 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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In Vivo Precipitation of Poorly Soluble Drugs from Lipid-Based Drug Delivery Systems
Sassene, P. J., Michaelsen, M. H., Mosgaard, M. D., Klitgaard, Mette, Van Den Broek, E., Wasan, K. M., Mu, Huiling, Rades, Thomas & Mullertz, Anette , 3 Oct 2016, In: Molecular Pharmaceutics. 13, 10, p. 3417-3426 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Influence of Copolymer Composition on In Vitro and In Vivo Performance of Celecoxib-PVP/VA Amorphous Solid Dispersions
Knopp, Matthias Manne, Nguyen, J. H., Mu, Huiling, Langguth, P., Rades, Thomas & Holm, R., Mar 2016, In: The A A P S Journal. 18, 2, p. 416-23 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Influence of PVP/VA copolymer composition on drug-polymer solubility
Rask, M. B., Knopp, Matthias Manne, Olesen, N. E., Holm, R. & Rades, Thomas, 31 Mar 2016, In: European Journal of Pharmaceutical Sciences. 85, p. 10-17 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Influence of polymer molecular weight on in vitro dissolution behavior and in vivo performance of celecoxib:PVP amorphous solid dispersions
Knopp, Matthias Manne, Nguyen, J. H., Becker, C., Francke, N. M., Jørgensen, E. B., Holm, P., Holm, R., Mu, Huiling, Rades, Thomas & Langguth, P., Apr 2016, In: European Journal of Pharmaceutics and Biopharmaceutics. 101, p. 145-51 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Influence of variation in molar ratio on co-amorphous drug-amino acid systems
Jensen, K. B. T., Larsen, F. H., Löbmann, Korbinian, Rades, Thomas & Grohganz, Holger, 2016, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 107, p. 32-39 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Inhalable Antimicrobials for Treatment of Bacterial Biofilm-Associated Sinusitis in Cystic Fibrosis Patients: Challenges and Drug Delivery Approaches
Klodzinska, S. N., Priemel, P. A., Rades, Thomas & Nielsen, Hanne Mørck, 9 Oct 2016, In: International Journal of Molecular Sciences . 17, 10, 19 p., 1688.Research output: Contribution to journal › Journal article › Research › peer-review
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Interlaboratory validation of small-scale solubility and dissolution measurements of poorly water-soluble drugs
Andersson, S. B. E., Alvebratt, C., Bevernage, J., Bonneau, D., Mathews, C. D. C., Dattani, R., Edueng, K., He, Y., Holm, R., Madsen, C. M., Müller, T., Muenster, U., Mullertz, Anette , Ojala, K., Rades, Thomas, Sieger, P. & Bergström, C. A. S., Sep 2016, In: Journal of Pharmaceutical Sciences. 105, 9, p. 2864-72 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Investigation of physical properties and stability of indomethacin-cimetidine and naproxen-cimetidine co-amorphous systems prepared by quench cooling, coprecipitation and ball milling
Lim, A. W., Löbmann, Korbinian, Grohganz, Holger, Rades, Thomas & Chieng, N., Jan 2016, In: Journal of Pharmacy and Pharmacology. 68, 1, p. 36-45 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Lipid-Based Formulations Can Enable the Model Poorly Water-Soluble Weakly Basic Drug Cinnarizine to Precipitate in an Amorphous-Salt Form during in Vitro Digestion
Khan, J., Rades, Thomas & Boyd, B. J., 2016, In: Molecular Pharmaceutics. 13, 11, p. 3783-3793 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Liposome-Based Adjuvants for Subunit Vaccines: Formulation Strategies for Subunit Antigens and Immunostimulators
Schmidt, S. T., Foged, Camilla, Korsholm, K. S., Rades, Thomas & Christensen, D., 10 Mar 2016, In: Pharmaceutics. 8, 1, 22 p., 7.Research output: Contribution to journal › Review › Research › peer-review
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Multispectral UV imaging for fast and non-destructive quality control of chemical and physical tablet attributes
Klukkert, M., Wu, J. X., Rantanen, Jukka, Carstensen, J. M., Rades, Thomas & Leopold, C. S., 2016, In: European Journal of Pharmaceutical Sciences. 90, p. 85-95 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Multispectral UV imaging for surface analysis of MUPS tablets with special focus on the pellet distribution
Novikova, A., Carstensen, J. M., Rades, Thomas & Leopold, P. D. C. S., 1 Oct 2016, In: International Journal of Pharmaceutics. 515, 1-2, p. 374-383 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Non-destructive Quality control of tablets and blister packs by UV imaging
Klukkert, M., Wu, J. X., Rantanen, Jukka, Rehder, S., Carstensen, J. M., Rades, Thomas & Leopold, C. S., 2016, In: Pharmazeutische Industrie. 78, 1, p. 108-120 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Poly(Alkyl Cyanoacrylate) nanoparticles for drug delivery and vaccine development
Graf, A., Krauel-Göllner, K. & Rades, Thomas, 19 Apr 2016, Colloids in Drug Delivery. CRC Press, p. 99-136 38 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Polymeric microcontainers improve oral bioavailability of furosemide
Nielsen, L. H., Melero, A., Keller, S. S., Jacobsen, Jette, Garrigues, T., Rades, Thomas, Mullertz, Anette & Boisen, A., 17 May 2016, In: International Journal of Pharmaceutics. 504, 1-2, p. 98-109 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Preparation and characterization of spray-dried co-amorphous drug-amino acid salts
Jensen, K. B. T., Blaabjerg, L. I., Lenz, E., Bohr, A., Grohganz, Holger, Kleinebudde, P., Rades, Thomas & Löbmann, Korbinian, May 2016, In: The Journal of pharmacy and pharmacology. 68, 5, p. 615–624 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Preparation and recrystallization behavior of spray-dried co-amorphous naproxen-indomethacin
Beyer, A., Radi, L., Grohganz, Holger, Löbmann, Korbinian, Rades, Thomas & Leopold, C. S., Jul 2016, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 104, p. 72-81 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Principles of controlled release
Perrie, Y., Rades, Thomas & Graeser, K., 15 Sep 2016, Drug Delivery: Fundamentals and Applications: Second Edition. CRC Press, p. 25-46 22 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Properties of the Sodium Naproxen-Lactose-Tetrahydrate Co-Crystal upon Processing and Storage
Sovago, I., Wang, W., Qiu, D., Raijada, D. K., Rantanen, Jukka, Grohganz, Holger, Rades, Thomas, Bond, A. D. & Löbmann, Korbinian, 2016, In: Molecules. 21, 4, p. 1-13 13 p., 509.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Recent advances and potential applications of modulated differential scanning calorimetry (mDSC) in drug development
Knopp, Matthias Manne, Löbmann, Korbinian, Elder, D. P., Rades, Thomas & Holm, R., 1 May 2016, In: European Journal of Pharmaceutical Sciences. 87, p. 164-173 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Recent advances in co-amorphous drug formulations
Dengale, S. J., Grohganz, Holger, Rades, Thomas & Löbmann, Korbinian, 1 May 2016, In: Advanced Drug Delivery Reviews. 100, p. 116-125 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Solvent free amorphisation for pediatric formulations (minitablets) using mesoporous silica
Monsuur, F., Choudhari, Y., Reddy, U., McCarthy, W., Sadek, I., Grohganz, Holger, Rades, Thomas & Löbmann, Korbinian, 25 Sep 2016, In: International Journal of Pharmaceutics. 511, 2, p. 1135-1136Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Statistical Analysis of a Method to Predict Drug-Polymer Miscibility
Knopp, Matthias Manne, Olesen, N. E., Huang, Y., Holm, R. & Rades, Thomas, 5 Jan 2016, In: Journal of Pharmaceutical Sciences. 105, 1, p. 362–367 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Studying the propensity of compounds to supersaturate: a practical and broadly applicable approach
Palmelund, H., Madsen, C. M., Christensen, J. P., Mullertz, Anette & Rades, Thomas, Oct 2016, In: Journal of Pharmaceutical Sciences. 105, 10, p. 3021-3029 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Supersaturation of zafirlukast in fasted and fed state intestinal media with and without precipitation inhibitors
Madsen, C. M., Boyd, B., Rades, Thomas & Mullertz, Anette , 25 Aug 2016, In: European Journal of Pharmaceutical Sciences. 91, p. 31-39 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The Effect of Digestion and Drug Load on Halofantrine Absorption from Self-nanoemulsifying Drug Delivery System (SNEDDS)
Michaelsen, M. H., Wasan, K. M., Sivak, O., Mullertz, Anette & Rades, Thomas, Jan 2016, In: The A A P S Journal. 18, 1, p. 180-186 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The Precipitation Behavior of Poorly Water-Soluble Drugs with an Emphasis on the Digestion of Lipid Based Formulations
Khan, J., Rades, Thomas & Boyd, B., Mar 2016, In: Pharmaceutical Research. 33, 3, p. 548-62 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The administration route is decisive for the ability of the vaccine adjuvant CAF09 to induce antigen-specific CD8(+) T-cell responses: The immunological consequences of the biodistribution profile
Schmidt, S. T., Khadke, S., Korsholm, K. S., Perrie, Y., Rades, Thomas, Andersen, P., Foged, Camilla & Christensen, D., 26 Aug 2016, In: Journal of controlled release : official journal of the Controlled Release Society. 239, p. 107-117 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The effect of surfactants on the dissolution behavior of amorphous formulations
Mah, P. T., Peltonen, L., Novakovic, D., Rades, Thomas, Strachan, C. J. & Laaksonen, T., Jun 2016, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 103, p. 13-22 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The influence of co-formers on the dissolution rates of co-amorphous sulfamerazine/excipient systems
Gniado, K., Löbmann, Korbinian, Rades, Thomas & Erxleben, A., 17 May 2016, In: International Journal of Pharmaceutics. 504, 1-2, p. 20-6 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Unintended and in situ amorphisation of pharmaceuticals
Priemel, P. A., Grohganz, Holger & Rades, Thomas, 1 May 2016, In: Advanced Drug Delivery Reviews. 100, p. 126-32 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 38132533
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Analysis of 3D Prints by X-ray Computed Microtomography and Terahertz Pulsed Imaging
Research output: Contribution to journal › Journal article › Research › peer-review
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361
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The significance of the amorphous potential energy landscape for dictating glassy dynamics and driving solid-state crystallisation
Research output: Contribution to journal › Journal article › Research › peer-review
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320
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Comparison of lipases for in vitro models of gastric digestion: lipolysis using two infant formulas as model substrates
Research output: Contribution to journal › Journal article › Research › peer-review
Published