Thomas Rades

Thomas Rades

Professor


  1. 2011
  2. An overview of recent studies on the analysis of pharmaceutical polymorphs

    Chieng, N., Rades, Thomas & Aaltonen, J., 2011, In: Journal of Pharmaceutical and Biomedical Analysis. 55, 4, p. 618-44 27 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Analysis of matrix dosage forms during dissolution testing using raman microscopy

    Haaser, M., Windbergs, M., McGoverin, C. M., Kleinebudde, P., Rades, Thomas, Gordon, K. C. & Strachan, C. J., 2011, In: Al Azhar Journal of Pharmaceutical Sciences.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Assessment of crystalline disorder in cryo-milled samples of indomethacin using atomic pair-wise distribution functions

    Bøtker, Johan Peter, Karmwar, P., Strachan, C. J., Cornett, Claus, Tian, F., Zujovic, Z., Rantanen, Jukka & Rades, Thomas, 2011, In: International Journal of Pharmaceutics. 417, 1-2, p. 112-119 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Coamorphous drug systems: enhanced physical stability and dissolution rate of indomethacin and naproxen

    Löbmann, Korbinian, Laitinen, R., Grohganz, Holger, Gordon, K. C., Strachan, C. & Rades, Thomas, 2011, In: Molecular Pharmaceutics. 8, 5, p. 1919-28 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Development and characterisation of modified poloxamer 407 thermoresponsive depot systems containing cubosomes

    Kojarunchitt, T., Hook, S., Rizwan, S., Rades, Thomas & Baldursdottir, S., 2011, In: International Journal of Pharmaceutics. 408, 1-2, p. 20-26 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Insights into the early dissolution events of amlodipine using UV imaging and Raman spectroscopy

    Bøtker, Johan Peter, Savolainen, M., Koradia, V., Tian, F., Rades, Thomas, Mullertz, Anette , Cornett, Claus, Rantanen, Jukka & Østergaard, Jesper, 2011, In: Molecular Pharmaceutics. 8, 4, p. 1372-1380 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Investigation of the formation process of two piracetam cocrystals during grinding

    Rehder, S., Klukkert, M., Löbmann, Korbinian, Strachan, C. J., Sakmann, A., Gordon, K., Rades, Thomas & Leopold, C. S., 2011, In: Pharmaceutics. 3, 4, p. 706-722 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Novel chitosan-magnesium aluminum silicate nanocomposite film coatings for modified-release tablets

    Khunawattanakul, W., Puttipipatkhachorn, S., Rades, Thomas & Pongjanyakul, T., 2011, In: International Journal of Pharmaceutics. 407, 1-2, p. 132-41 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Release and bioactivity of PACA nanoparticles containing D-Lys6-GnRH for brushtail possum fertility control

    Kafka, A. P., McLeod, B. J., Rades, Thomas & McDowell, A., 2011, In: Journal of controlled release : official journal of the Controlled Release Society. 149, 3, p. 307-13 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. The application of MALDI TOF MS in biopharmaceutical research

    Kafka, A. P., Kleffmann, T., Rades, Thomas & McDowell, A., 2011, In: International Journal of Pharmaceutics. 417, 1-2, p. 70-82 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. 2010
  13. Published

    The role of configurational entropy in amorphous systems

    Graeser, K. A., Patterson, J. E., Zeitler, J. A. & Rades, Thomas, Jun 2010, In: Pharmaceutics. 2, 2, p. 224-244 21 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    From Water to Ice: Investigation of the Effect of Ice Crystal Reduction on the Stability of Frozen Large Unilamellar Vesicles

    Siow, L. F., Rades, Thomas & Lim, M. H., 14 May 2010, Water Properties in Food, Health, Pharmaceutical and Biological Systems: ISOPOW 10. Wiley-Blackwell, p. 551-562 12 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  15. Published

    Physical Changes in Confectionery Products Caused by the Availability of Water, with a Special Focus on Lactitol Crystallization

    Lim, M. H., Lampen, B., Siow, L. F. & Rades, Thomas, 14 May 2010, Water Properties in Food, Health, Pharmaceutical and Biological Systems: ISOPOW 10. Wiley-Blackwell, p. 271-282 12 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  16. Published

    Deeper insight into the drug release mechanisms in Eudragit RL-based delivery systems

    Glaessl, B., Siepmann, F., Tucker, I., Rades, Thomas & Siepmann, J., 15 Apr 2010, In: International Journal of Pharmaceutics. 389, 1-2, p. 139-146 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Rapid and specific high-performance liquid chromatography for the in vitro quantification of D-Lys6-GnRH in a microemulsion-type formulation in the presence of peptide oxidation products

    Kafka, A. P., Rades, Thomas & McDowell, A., Feb 2010, In: Biomedical Chromatography. 24, 2, p. 132-139 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. "This body does not want free medicines": South African consumer perceptions of drug quality

    Patel, A., Gauld, R., Norris, P. & Rades, Thomas, 2010, In: Health Policy and Planning. 25, 1, p. 61-9 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    An oral delivery system for indomethicin engineered from cationic lipid emulsions and silica nanoparticles

    Simovic, S., Hui, H., Song, Y., Davey, A. K., Rades, Thomas & Prestidge, C. A., 2010, In: Journal of controlled release : official journal of the Controlled Release Society. 143, 3, p. 367-73 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Bicontinuous cubic liquid crystals as sustained delivery systems for peptides and proteins

    Rizwan, S. B., Boyd, B. J., Rades, Thomas & Hook, S., 2010, In: Expert Opinion on Drug Delivery. 7, 10, p. 1133-44 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Characterization of Peptide Polymer Interactions in Poly(alkylcyanoacrylate) Nanoparticles: A Mass Spectrometric Approach

    Kafka, A. P., Kleffmann, T., Rades, Thomas & McDowell, A., 2010, In: Current Drug Delivery.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Chitosan-magnesium aluminum silicate nanocomposite films: physicochemical characterization and drug permeability

    Khunawattanakul, W., Puttipipatkhachorn, S., Rades, Thomas & Pongjanyakul, T., 2010, In: International Journal of Pharmaceutics. 393, 1-2, p. 219-29 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Investigating dissolution performance critical areas on coated tablets: a case study using terahertz pulsed imaging

    Ho, L., Müller, R., Krüger, C., Gordon, K. C., Kleinebudde, P., Pepper, M., Rades, Thomas, Shen, Y., Taday, P. F. & Zeitler, J. A., 2010, In: Al Azhar Journal of Pharmaceutical Sciences. 99, 1, p. 392-402 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Mathematical modeling of drug release from Eudragit RS-based delivery systems

    Glaessl, B., Siepmann, F., Tucker, I., Rades, Thomas & Siepmann, J., 2010, In: Journal of Drug Delivery Science and Technology. 20, 2, p. 127-133 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Mechanical properties of excipients do not affect polymer matrix formation

    Chatterjee, L., Rades, Thomas & Tucker, I. G., 2010, In: International Journal of Pharmaceutics. 384, 1-2, p. 87-92 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    New perspectives on lipid and surfactant based drug delivery systems for oral delivery of poorly soluble drugs

    Mullertz, Anette , Ogbonna, A., Ren, S. & Rades, Thomas, 2010, In: Journal of Pharmacy and Pharmacology. 62, 11, p. 1622-1636 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Precipitation of a poorly soluble model drug during in vitro lilpolysis: characterization and dissolution of the precipitate

    Sassene, P. J., Knopp, Matthias Manne, Hesselkilde, J. Z., Koradia, V., Larsen, A., Rades, Thomas & Mullertz, Anette , 2010, In: Journal of Pharmaceutical Sciences. 99, 12, p. 4982-4991

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Silica nanoparticles to control the lipase-mediated digestion of lipid-based oral delivery systems

    Tan, A., Simovic, S., Davey, A. K., Rades, Thomas, Boyd, B. J. & Prestidge, C. A., 2010, In: Molecular Pharmaceutics. 7, 2, p. 522-32 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Themed issue: improve dissolution, solubility and bioavailability of poorly soluble drugs

    Perrie, Y. & Rades, Thomas, 2010, In: Journal of Pharmacy and Pharmacology. 62, 11, p. 1517-8 2 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  30. 2009
  31. Published

    Polymeric nanoparticles as an oral delivery system for biocontrol agents for the brushtail possum (trichosurus vulpecula)

    McDowell, A., Rades, Thomas, Tucker, I. G. & McLeod, B. J., Dec 2009, In: New Zealand Veterinary Journal. 57, 6, p. 370-377 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Liquid crystalline systems of phytantriol and glyceryl monooleate containing a hydrophilic protein: Characterisation, swelling and release kinetics

    Rizwan, S. B., Hanley, T., Boyd, Ben, Rades, Thomas & Hook, S., Nov 2009, In: Journal of Pharmaceutical Sciences. 98, 11, p. 4191-4204 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Histidine residues in the peptide D-Lys6-GnRH: Potential for copolymerization in polymeric nanoparticles

    Kafka, A. P., Kleffmann, T., Rades, Thomas & McDowell, A., 5 Oct 2009, In: Molecular Pharmaceutics. 6, 5, p. 1483-1491 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Predicting the drug release kinetics of matrix tablets

    Baeumer, B., Chatterjee, L., Hinow, P., Rades, Thomas, Radunskaya, A. & Tucker, I., Sep 2009, In: Discrete and Continuous Dynamical Systems - Series B. 12, 2, p. 261-277 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Analysis of solid-state transformations of pharmaceutical compounds using vibrational spectroscopy

    Heinz, Andrea, Strachan, C. J., Gordon, K. C. & Rades, Thomas, Aug 2009, In: The Journal of pharmacy and pharmacology. 61, 8, p. 971-88 18 p.

    Research output: Contribution to journalReviewResearchpeer-review

  36. Published

    Formation kinetics and stability of carbamazepine-nicotinamide cocrystals prepared by mechanical activation

    Chieng, N., Hubert, M., Saville, D., Rades, Thomas & Aaltonen, J., 6 May 2009, In: Crystal Growth and Design. 9, 5, p. 2377-2386 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Towards physico-relevant dissolution testing: The importance of solid-state analysis in dissolution

    Aaltonen, J. & Rades, Thomas, May 2009, In: Dissolution Technologies. 16, 2, p. 47-54 8 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  38. Published

    The synthesis and immune stimulating action of mannose-capped lysine-based dendrimers

    Greatrex, B. W., Brodie, S. J., Furneaux, R. H., Hook, S. M., McBurney, W. T., Painter, G. F., Rades, Thomas & Rendle, P. M., 11 Apr 2009, In: Tetrahedron. 65, 15, p. 2939-2950 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Method of preparation does not affect the miscibility between steroid hormone and polymethacrylate

    Wiranidchapong, C., Rades, Thomas, Kulvanich, P. & Tucker, I. G., 10 Mar 2009, In: Thermochimica Acta. 485, 1-2, p. 57-64 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Physical characterization and stability of amorphous indomethacin and ranitidine hydrochloride binary systems prepared by mechanical activation

    Chieng, N., Aaltonen, J., Saville, D. & Rades, Thomas, Jan 2009, In: European Journal of Pharmaceutics and Biopharmaceutics. 71, 1, p. 47-54 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Advances in lipid-based subunit vaccine formulations

    Myschik, J., Rades, Thomas & Hook, S., 2009, In: Current Immunology Reviews.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Applying thermodynamic and kinetic parameters to predict the physical stability of two differently prepared amorphous forms of simvastatin

    Graeser, K. A., Patterson, J. E. & Rades, Thomas, 2009, In: Current Drug Delivery. 6, 4, p. 374-82 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Characterisation of quaternary polymethacrylate films containing tartaric acid, metoprolol free base or metoprolol tartrate

    Glaessl, B., Siepmann, F., Tucker, I., Siepmann, J. & Rades, Thomas, 2009, In: European Journal of Pharmaceutics and Biopharmaceutics.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Correlating thermodynamic and kinetic parameters with amorphous stability

    Graeser, K. A., Patterson, J. E., Zeitler, J. A., Gordon, K. C. & Rades, Thomas, 2009, In: European Journal of Pharmaceutical Sciences. 37, 3-4, p. 492-8 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Development of a novel magnetic resonance imaging contrast agent for pressure measurements using lipid-coated microbubbles

    Kaur, R., Morris, R., Bencsik, M., Vangala, A., Rades, Thomas & Perrie, Y., 2009, In: Journal of Biomedical Nanotechnology. 5, 6, p. 707-15 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Drug quality in South Africa: perceptions of key players involved in medicines distribution

    Patel, A., Norris, P., Gauld, R. & Rades, Thomas, 2009, In: International Journal of Health Care Quality Assurance. 22, 5, p. 547-60 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Effects of film coating thickness and drug layer uniformity on in vitro drug release from sustained-release coated pellets: a case study using terahertz pulsed imaging

    Ho, L., Cuppok, Y., Muschert, S., Gordon, K. C., Pepper, M., Shen, Y., Siepmann, F., Siepmann, J., Taday, P. F. & Rades, Thomas, 2009, In: International Journal of Pharmaceutics. 382, 1-2, p. 151-9 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Effects of some terpenes on the in vitro permeation of LHRH through newborn pig skin

    Songkro, S., Rades, Thomas & Becket, G., 2009, In: Pharmazie.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Influence of particle size and preparation methods on the physical and chemical stability of amorphous simvastatin

    Zhang, F., Aaltonen, J., Tian, F., Saville, D. J. & Rades, Thomas, 2009, In: European Journal of Pharmaceutics and Biopharmaceutics. 71, 1, p. 64-70 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Mannosylated saponins based on oleanolic and glycyrrhizic acids. Towards synthetic colloidal antigen delivery systems

    Daines, A. M., Greatrex, B. W., Hayman, C. M., Hook, S. M., McBurney, W. T., Rades, Thomas, Rendle, P. M. & Sims, I. M., 2009, In: Bioorganic & Medicinal Chemistry Letters. 17, 14, p. 5207-18 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Monitoring the film coating unit operation and predicting drug dissolution using terahertz pulsed imaging

    Ho, L., Müller, R., Gordon, K. C., Kleinebudde, P., Pepper, M., Rades, Thomas, Shen, Y., Taday, P. F. & Zeitler, J. A., 2009, In: Al Azhar Journal of Pharmaceutical Sciences. 98, 12, p. 4866-76 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Noninvasive 3D characterization of layered samples using terahertz pulsed imaging and infrared Optical Coherence Tomography

    Zhong, S., Shen, H., Shen, Y. C., Zeitler, J. A., Ho, L., Evans, M., Taday, P. T., Pepper, M., Rades, Thomas, Gordon, K. C., Muller, R. & Kleinebudde, P., 2009, 34th International Conference on Infrared, Millimeter, and Terahertz Waves, IRMMW-THz 2009. 5324630. (34th International Conference on Infrared, Millimeter, and Terahertz Waves, IRMMW-THz 2009).

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

  53. Nonlamellar liquid crystalline nanostructured particles: advances in materials and structure determination

    Boyd, B. J., Dong, Y. & Rades, Thomas, 2009, In: Journal of Liposome Research. 19, 1, p. 12-28 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 38132533