Thomas Rades
Professor
Pharmaceuticals, processes and products
Universitetsparken 2
2100 København Ø
Perspectives in the use of spectroscopy to characterise pharmaceutical solids
Aaltonen, J., Gordon, K. C., Strachan, C. J. & Rades, Thomas, 2008, In: International Journal of Pharmaceutics. 364, 2, p. 159-69 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Towards physico-relevant dissolution testing: The importance of solid-state analysis in dissolution
Aaltonen, J. & Rades, Thomas, May 2009, In: Dissolution Technologies. 16, 2, p. 47-54 8 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
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Ranitidine hydrochloride X-ray assay using a neural network
Agatonovic-Kustrin, S., Wu, V., Rades, Thomas, Saville, D. & Tucker, I. G., Jul 2000, In: Journal of Pharmaceutical and Biomedical Analysis. 22, 6, p. 985-992 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Powder diffractometric assay of two polymorphic forms of ranitidine hydrochloride
Agatonovic-Kustrin, S., Wu, V., Rades, Thomas, Saville, D. & Tucker, I. G., 5 Jul 1999, In: International Journal of Pharmaceutics. 184, 1, p. 107-114 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Determination of polymorphic forms of ranitidine-HCl by DRIFTS and XRPD
Agatonovic-Kustrin, S., Rades, Thomas, Wu, V., Saville, D. & Tucker, I. G., 2001, In: Journal of Pharmaceutical and Biomedical Analysis.Research output: Contribution to journal › Journal article › Research › peer-review
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Highly Elastic and Water Stable Zein Microfibers as a Potential Drug Delivery System for Wound Healing
Akhmetova, A., Lanno, G., Kogermann, K., Malmsten, Martin, Rades, Thomas & Heinz, Andrea, 2020, In: Pharmaceutics. 12, 5, 19 p., 458.Research output: Contribution to journal › Journal article › Research › peer-review
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Difficulties of Subsurface Liquid Front Tracking in Porous Media with Terahertz Pulsed Imaging
Al-Sharabi, M., Mudley, T., Markl, D., Bawuah, P., Karttunen, A. P., Ridgway, C. J., Gane, P. A. C., Ketolainen, J., Peiponen, K. E., Rades, Thomas & Zeitler, J. A., 2019, 2019 - 44th International Conference on Infrared, Millimeter, and Terahertz Waves. IEEE, 8874143. (International Conference on Infrared, Millimeter, and Terahertz Waves, IRMMW-THz, Vol. 2019-September).Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review
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Simultaneous investigation of the liquid transport and swelling performance during tablet disintegration
Al-Sharabi, M., Markl, D., Mudley, T., Bawuah, P., Karttunen, A., Ridgway, C., Gane, P., Ketolainen, J., Peiponen, K., Rades, Thomas & Zeitler, J. A., 2020, In: International Journal of Pharmaceutics. 584, 11 p., 119380.Research output: Contribution to journal › Journal article › Research › peer-review
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Use of artificial neural networks to predict quaternery phase systems from limited experimental data
Alany, R. G., Agatonovic-Kustrin, S., Rades, Thomas & Tucker, I. G., 1 Mar 1999, In: Journal of Pharmaceutical and Biomedical Analysis. 19, 3-4, p. 443-452 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Characterizing colloidal structures of pseudoternary phase diagrams formed by oil/water/amphiphile systems
Alany, R. G., Tucker, I. G., Davies, N. M. & Rades, Thomas, 2001, In: Drug Development and Industrial Pharmacy.Research output: Contribution to journal › Journal article › Research › peer-review
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W/O microemulsions for ocular delivery: Evaluation of ocular irritation and precorneal retention
Alany, R. G., Rades, Thomas, Nicoll, J., Tucker, I. G. & Davies, N. M., 2006, In: Journal of Controlled Release.Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of alcohols and diols on the phase behaviour of quaternary systems
Alany, R. G., Rades, Thomas, Agatonovic-Kustrin, S., Davies, N. M. & Tucker, I. G., 2000, In: International Journal of Pharmaceutics.Research output: Contribution to journal › Journal article › Research › peer-review
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The biomolecular gastrointestinal corona in oral drug delivery
Aljabbari, Anas Samir Mohammad, Kihara, Shinji, Rades, Thomas & Boyd, Ben, 2023, In: Journal of controlled release : official journal of the Controlled Release Society. 363, p. 536-549Research output: Contribution to journal › Review › Research › peer-review
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Elucidating the nanostructure of small interfering RNA-loaded lipidoid-polymer hybrid nanoparticles
Aljabbari, Anas Samir Mohammad, Lokras, Abhijeet, Kirkensgaard, Jacob Judas Kain, Rades, Thomas, Franzyk, Henrik, Thakur, A., Zhang, Y. & Foged, Camilla, 2023, In: Journal of Colloid and Interface Science. 633, p. 907-922Research output: Contribution to journal › Journal article › Research › peer-review
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The Influence of Gastrointestinal Biomolecules on Solid-State Transformations in Pharmaceutical Particulates
Aljabbari, Anas Samir Mohammad, Kihara, Shinji, Rades, Thomas, Boyd, Ben & Bērziņš, Kārlis, 2023, In: Molecular Pharmaceutics. 20, 8, p. 4297-4306Research output: Contribution to journal › Journal article › Research › peer-review
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Interlaboratory validation of small-scale solubility and dissolution measurements of poorly water-soluble drugs
Andersson, S. B. E., Alvebratt, C., Bevernage, J., Bonneau, D., Mathews, C. D. C., Dattani, R., Edueng, K., He, Y., Holm, R., Madsen, C. M., Müller, T., Muenster, U., Mullertz, Anette , Ojala, K., Rades, Thomas, Sieger, P. & Bergström, C. A. S., Sep 2016, In: Journal of Pharmaceutical Sciences. 105, 9, p. 2864-72 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Characterisation of indomethacin and nifedipine using variable-temperature solid-state NMR
Apperley, D. C., Forster, A. H., Fournier, R., Harris, R. K., Hodgkinson, P., Lancaster, R. W. & Rades, Thomas, 2005, In: Magnetic Resonance in Chemistry. 43, 11, p. 881-92 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Melt Extrusion of High-Dose Co-Amorphous Drug-Drug Combinations
Arnfast, L., Kamruzzaman, M., Löbmann, Korbinian, Aho, J., Baldursdottir, S., Rades, Thomas & Rantanen, Jukka, Dec 2017, In: Pharmaceutical Research. 34, 12, p. 2689-2697Research output: Contribution to journal › Journal article › Research › peer-review
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Interdependence of Dosage Form Microstructure and Performance
Axel Zeitler, J. & Rades, Thomas, May 2017, In: Pharmaceutical Research. 34, 5, p. 887-889 3 p.Research output: Contribution to journal › Editorial › Research › peer-review
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Time-resolved terahertz spectroscopy: Polymorphic solid state phase transitions in carbamazepine
Axel Zeitler, J., Taday, P. F., Gordon, K. C., Pepper, M. & Rades, Thomas, 2007, IRMMW-THz2007 - Conference Digest of the Joint 32nd International Conference on Infrared and Millimetre Waves, and 15th International Conference on Terahertz Electronics.Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review
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Predicting the drug release kinetics of matrix tablets
Baeumer, B., Chatterjee, L., Hinow, P., Rades, Thomas, Radunskaya, A. & Tucker, I., Sep 2009, In: Discrete and Continuous Dynamical Systems - Series B. 12, 2, p. 261-277 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Improving the drug load and in vitro performance of supersaturated self-nanoemulsifying drug delivery systems (super-SNEDDS) using polymeric precipitation inhibitors
Bannow, J., Yorulmaz, Y., Löbmann, Korbinian, Mullertz, Anette & Rades, Thomas, 2020, In: International Journal of Pharmaceutics. 575, 1188960.Research output: Contribution to journal › Journal article › Research › peer-review
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Hot Melt Coating of Amorphous Carvedilol
Bannow, J., Koren, L., Salar-Behzadi, S., Löbmann, Korbinian, Zimmer, A. & Rades, Thomas, 2020, In: Pharmaceutics. 12, 6, 13 p., 519.Research output: Contribution to journal › Journal article › Research › peer-review
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Direct Measurement of Lateral Molecular Diffusivity on the Surface of Supersaturated Amorphous Solid Dispersions by Atomic Force Microscopy
Bannow, J., Karl, M., Larsen, P. E., Hwu, E. T. & Rades, Thomas, 2020, In: Molecular Pharmaceutics. 17, 5, p. 1715-1722 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Biorelevant intrinsic dissolution profiling in early drug development: Fundamental, methodological, and industrial aspects
Bergstrom, C. A. S., Box, K., Holm, R., Matthews, W., McAllister, M., Mullertz, Anette , Rades, Thomas, Schaefer, K. J. & Teleki, A., Jun 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 139, p. 101-114Research output: Contribution to journal › Review › Research › peer-review
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Self-emulsifying drug delivery systems (SEDDS) – The splendid comeback of an old technology
Bernkop-Schnürch, A., Mullertz, Anette & Rades, Thomas, 2019, In: Advanced Drug Delivery Reviews. 142, p. 1-2 2 p.Research output: Contribution to journal › Editorial › Research › peer-review
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Evaluating Oral Drug Delivery Systems: Dissolution Models.
Berthelsen, R., Mullertz, Anette & Rades, Thomas, 2016, Analytical Techniques in the Pharmaceutical Sciences. Springer, p. 753-771Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Evaluating Oral Drug Delivery Systems: Digestion Models.
Berthelsen, R., Sassene, P., Rades, Thomas & Mullertz, Anette , 2016, Analytical Techniques in the Pharmaceutical Sciences. Springer, p. 753-771Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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In vitro digestion models to evaluate lipid based drug delivery systems; present status and current trends
Berthelsen, R., Klitgaard, Mette, Rades, Thomas & Mullertz, Anette , 29 Jun 2019, In: Advanced Drug Delivery Reviews. 142, p. 35-49 15 p.Research output: Contribution to journal › Review › Research › peer-review
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Combined Effect of the Preparation Method and Compression on the Physical Stability and Dissolution Behavior of Melt-Quenched Amorphous Celecoxib
Bērziņš, Kārlis, Fraser-Miller, S. J., Di, Rong, Liu, J., Peltonen, L., Strachan, C. J., Rades, Thomas & Gordon, K. C., 2021, In: Molecular Pharmaceutics. 18, 3, p. 1408-1418Research output: Contribution to journal › Journal article › Research › peer-review
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Solving the Computational Puzzle: Toward a Pragmatic Pathway for Modeling Low-Energy Vibrational Modes of Pharmaceutical Crystals
Bērziņš, Kārlis, Sutton, J. J., Fraser-Miller, S. J., Rades, Thomas, Korter, T. M. & Gordon, K. C., 2020, In: Crystal Growth & Design. 20, 10, p. 6947-6955Research output: Contribution to journal › Journal article › Research › peer-review
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Improvement of the physicochemical properties of Co-amorphous naproxen-indomethacin by naproxen-sodium
Beyer, A., Grohganz, Holger, Löbmann, Korbinian, Rades, Thomas & Leopold, C. S., 30 Jun 2017, In: International Journal of Pharmaceutics. 526, 1-2, p. 88-94 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Multivariate Quantification of the Solid State Phase Composition of Co-Amorphous Naproxen-Indomethacin
Beyer, A., Grohganz, Holger, Löbmann, Korbinian, Rades, Thomas & Leopold, C. S., 2015, In: Molecules. 20, 10, p. 19571-87 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Preparation and recrystallization behavior of spray-dried co-amorphous naproxen-indomethacin
Beyer, A., Radi, L., Grohganz, Holger, Löbmann, Korbinian, Rades, Thomas & Leopold, C. S., Jul 2016, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 104, p. 72-81 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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INFLUENCE OF THE COOLING RATE AND THE BLEND RATIO ON THE PHYSICAL STABILTIY OF CO-AMORPHOUS NAPROXEN/INDOMETHACIN
Beyer, A., Grohganz, Holger, Löbmann, Korbinian, Rades, Thomas & Leopold, C. S., 13 Oct 2016, In: European Journal of Pharmaceutics and Biopharmaceutics. 109, p. 140-148 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Investigation on Formulation Strategies to Mitigate Compression-Induced Destabilization in Supersaturated Celecoxib Amorphous Solid Dispersions
Bērziņš, Kārlis, Fraser-Miller, S. J., Walker, G. F., Rades, Thomas & Gordon, K. C., 2021, In: Molecular Pharmaceutics. 18, 10, p. 3882–3893Research output: Contribution to journal › Journal article › Research › peer-review
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Influence of Glass Forming Ability on the Physical Stability of Supersaturated Amorphous Solid Dispersions
Blaabjerg, L. I., Bulduk, B., Lindenberg, E., Löbmann, Korbinian, Rades, Thomas & Grohganz, Holger, 1 Jan 2019, In: Journal of Pharmaceutical Sciences. 108, 8, p. 2561-2569Research output: Contribution to journal › Journal article › Research › peer-review
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Influence of preparation pathway on the glass forming ability
Blaabjerg, L. I., Lindenberg, E., Rades, Thomas, Grohganz, Holger & Löbmann, Korbinian, 21 Apr 2017, In: International Journal of Pharmaceutics. 521, 1-2, p. 232-238Research output: Contribution to journal › Journal article › Research › peer-review
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Is there a correlation between the glass forming ability of a drug and its supersaturation propensity?
Blaabjerg, L. I., Lindenberg, E., Löbmann, Korbinian, Grohganz, Holger & Rades, Thomas, 1 Mar 2018, In: International Journal of Pharmaceutics. 538, 1-2, p. 243-249Research output: Contribution to journal › Journal article › Research › peer-review
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Glass forming ability of amorphous drugs investigated by continuous cooling- and isothermal transformation
Blaabjerg, L. I., Lindenberg, E., Löbmann, Korbinian, Grohganz, Holger & Rades, Thomas, 2016, In: Molecular Pharmaceutics. 13, 9, p. 3318-3325 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The Influence of Polymers on the Supersaturation Potential of Poor and Good Glass Formers
Blaabjerg, L. I., Grohganz, Holger, Lindenberg, E., Löbmann, Korbinian, Mullertz, Anette & Rades, Thomas, 21 Sep 2018, In: Pharmaceutics. 10, 4, 14 p., 164.Research output: Contribution to journal › Journal article › Research › peer-review
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Additive manufacturing in respiratory sciences – Current applications and future prospects
Bock, S., Rades, Thomas, Rantanen, Jukka & Scherließ, R., 2022, In: Advanced Drug Delivery Reviews. 186, 14 p., 114341.Research output: Contribution to journal › Review › Research › peer-review
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Insights into the early dissolution events of amlodipine using UV imaging and Raman spectroscopy
Bøtker, Johan Peter, Savolainen, M., Koradia, V., Tian, F., Rades, Thomas, Mullertz, Anette , Cornett, Claus, Rantanen, Jukka & Østergaard, Jesper, 2011, In: Molecular Pharmaceutics. 8, 4, p. 1372-1380 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Application of spray-drying and electrospraying/electospinning for poorly water-soluble drugs: a particle engineering approach
Bohr, A., Bøtker, Johan Peter, Rades, Thomas, Rantanen, Jukka & Yang, Mingshi, 2014, In: Current Pharmaceutical Design. 20, 3, p. 325-48 24 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Efflux Inhibitor Bicalutamide Increases Oral Bioavailability of the Poorly Soluble Efflux Substrate Docetaxel in Co-Amorphous Anti-Cancer Combination Therapy
Bohr, A., Nascimento, T. L., Harmankaya, N., Weisser, J. J., Wang, Y., Grohganz, Holger, Rades, Thomas & Löbmann, Korbinian, 2019, In: Molecules. 24, 2, 13 p., 266.Research output: Contribution to journal › Journal article › Research › peer-review
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Application of spray-drying and electrospraying/electospinning for poorly water-soluble drugs: a particle engineering approach
Bohr, A. J., Bøtker, Johan Peter, Rades, Thomas, Rantanen, Jukka & Yang, Mingshi, 2013, In: Current Pharmaceutical Design. 20, 3, p. 325-348Research output: Contribution to journal › Journal article › Research › peer-review
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Characterisation of microstructures formed in isopropyl palmitate/water/Aerosol®OT: 1-butanol (2:1) system
Boonme, P., Krauel, K., Graf, A., Rades, Thomas & Junyaprasert, V. B., 2006, In: Pharmazie.Research output: Contribution to journal › Journal article › Research › peer-review
Characterization of microemulsion structures in the pseudoternary phase diagram of isopropyl palmitate/water/Brij 97:1-butanol
Boonme, P., Krauel, K., Graf, A., Rades, Thomas & Junyaprasert, V. B., 2006, In: A A P S PharmSciTech. 7, 2, p. E45Research output: Contribution to journal › Journal article › Research › peer-review
Nonlamellar liquid crystalline nanostructured particles: advances in materials and structure determination
Boyd, B. J., Dong, Y. & Rades, Thomas, 2009, In: Journal of Liposome Research. 19, 1, p. 12-28 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
Self-assembled geometric liquid-crystalline nanoparticles imaged in three dimensions: hexosomes are not necessarily flat hexagonal prisms
Boyd, B. J., Rizwan, S. B., Dong, Y., Hook, S. & Rades, Thomas, 2007, In: Langmuir. 23, 25, p. 12461-4 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
Thermotropic liquid crystalline drugs
Bunjes, H. & Rades, Thomas, 2005, In: Journal of Pharmacy and Pharmacology. 57, 7, p. 807-16 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Determination of methylphenidate in Calliphorid larvae by liquid-liquid extraction and liquid chromatography mass spectrometry - Forensic entomotoxicology using an in vivo rat brain model
Bushby, S. K., Thomas, N., Priemel, P. A., Coulter, C. V., Rades, Thomas & Kieser, J. A., 2012, In: Journal of Pharmaceutical and Biomedical Analysis. 70, p. 456-61 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Assessment of crystalline disorder in cryo-milled samples of indomethacin using atomic pair-wise distribution functions
Bøtker, Johan Peter, Karmwar, P., Strachan, C. J., Cornett, Claus, Tian, F., Zujovic, Z., Rantanen, Jukka & Rades, Thomas, 2011, In: International Journal of Pharmaceutics. 417, 1-2, p. 112-119 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Anhydrate to hydrate solid-state transformations of carbamazepine and nitrofurantoin in biorelevant media studied in situ using time-resolved synchrotron X-ray diffraction
Bøtker, Johan Peter, Rantanen, Jukka, Arnfast, L., Doreth, M., Raijada, D. K., Löbmann, Korbinian, Madsen, C. M., Khan, J., Rades, Thomas, Mullertz, Anette , Hawley, A., Thomas, D. & Boyd, B. J., Mar 2016, In: European Journal of Pharmaceutics and Biopharmaceutics. 100, p. 119-127 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Structural elucidationof rapid solution-mediatedPhase transitions in pharmaceutical solids using in situ synchrotron SAXS/WAXS
Bøtker, Johan Peter, Rades, Thomas, Rantanen, Jukka, Hawley, A. & Boyd, B. J., 1 Aug 2012, In: Molecular Pharmaceutics. 9, 9, p. 2787-2791Research output: Contribution to journal › Journal article › Research › peer-review
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A new approach to dissolution testing by UV imaging and finite element simulations
Bøtker, Johan Peter, Rantanen, Jukka, Rades, Thomas, Mullertz, Anette , Østergaard, Jesper & Jensen, H., 2013, In: Pharmaceutical Research. 30, 5, p. 1328-1337Research output: Contribution to journal › Journal article › Research › peer-review
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Low-Frequency Raman Spectroscopy as an Avenue to Determine the Transition Temperature of β- and γ-Relaxation in Pharmaceutical Glasses
Bērziņš, Kārlis, Fraser-Miller, S. J., Rades, Thomas & Gordon, K. C., 2022, In: Analytical Chemistry. 94, 23, p. 8241-8248Research output: Contribution to journal › Journal article › Research › peer-review
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Low-Frequency Raman Spectroscopic Study on Compression-Induced Destabilization in Melt-Quenched Amorphous Celecoxib
Bērziņš, Kārlis, Fraser-Miller, S. J., Rades, Thomas & Gordon, K. C., 2019, In: Molecular Pharmaceutics. 16, 8, p. 3678-3686 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Characterization and in vitro permeation study of microemulsions and liquid crystalline systems containing the anticholinesterase alkaloidal extract from Tabernaemontana divaricata
Chaiyana, W., Rades, Thomas & Okonogi, S., 16 Aug 2013, In: International Journal of Pharmaceutics. 452, 1-2, p. 201-210 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Predictive identification of co-formers in co-amorphous systems
Chambers, L. I., Grohganz, Holger, Palmelund, H., Löbmann, Korbinian, Rades, Thomas, Musa, O. M. & Steed, J. W., 2021, In: European Journal of Pharmaceutical Sciences. 157, 9 p., 105636.Research output: Contribution to journal › Journal article › Research › peer-review
Mechanical properties of excipients do not affect polymer matrix formation
Chatterjee, L., Rades, Thomas & Tucker, I. G., 2010, In: International Journal of Pharmaceutics. 384, 1-2, p. 87-92 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effect of milling conditions on the solid-state conversion of ranitidine hydrochloride form 1
Chieng, N., Zujovic, Z., Bowmaker, G., Rades, Thomas & Saville, D., 2006, In: International Journal of Pharmaceutics.Research output: Contribution to journal › Journal article › Research › peer-review
An overview of recent studies on the analysis of pharmaceutical polymorphs
Chieng, N., Rades, Thomas & Aaltonen, J., 2011, In: Journal of Pharmaceutical and Biomedical Analysis. 55, 4, p. 618-44 27 p.Research output: Contribution to journal › Journal article › Research › peer-review
Quantitative solid-state analysis of three solid forms of ranitidine hydrochloride in ternary mixtures using Raman spectroscopy and X-ray powder diffraction
Chieng, N., Rehder, S., Saville, D., Rades, Thomas & Aaltonen, J., 2009, In: Journal of Pharmaceutical and Biomedical Analysis. 49, 1, p. 18-25 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
Formation and physical stability of the amorphous phase of ranitidine hydrochloride polymorphs prepared by cryo-milling
Chieng, N., Rades, Thomas & Saville, D., 2008, In: European Journal of Pharmaceutics and Biopharmaceutics. 68, 3, p. 771-80 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Physical characterization and stability of amorphous indomethacin and ranitidine hydrochloride binary systems prepared by mechanical activation
Chieng, N., Aaltonen, J., Saville, D. & Rades, Thomas, Jan 2009, In: European Journal of Pharmaceutics and Biopharmaceutics. 71, 1, p. 47-54 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Formation kinetics and stability of carbamazepine-nicotinamide cocrystals prepared by mechanical activation
Chieng, N., Hubert, M., Saville, D., Rades, Thomas & Aaltonen, J., 6 May 2009, In: Crystal Growth and Design. 9, 5, p. 2377-2386 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Rapid insight into heating-induced phase transformations in the solid state of the calcium salt of atorvastatin using multivariate data analysis
Christensen, N. P. A., Van Eerdenbrugh, B., Kwok, K., Taylor, L. S., Bond, A., Rades, Thomas, Rantanen, Jukka & Cornett, Claus, Mar 2013, In: Pharmaceutical Research. 30, 3, p. 826-35 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Formation of drug nanocrystals under nanoconfinement afforded by liposomes
Cipolla, D., Wu, H., Salentinig, S., Boyd, B., Rades, Thomas, Vanhecke, D., Petri-Fink, A., Rothin-Rutishauser, B., Eastman, S., Redelmeier, T., Gonda, I. & Chan, H., 2016, In: RSC Advances. 6, 8, p. 6223-6233 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Erratum: Formation of drug nanocrystals under nanoconfinement afforded by liposomes (RSC Adv. (2016) 6 (6223-6233))
Cipolla, D., Wu, H., Salentinig, S., Boyd, Ben, Rades, Thomas, Vanhecke, D., Petri-Fink, A., Rothen-Rutishauser, B., Eastman, S., Redelmeier, T., Gonda, I. & Chan, H. K., 2016, In: RSC Advances. 6, 15, p. 12123 1 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
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Hydration of lipid films with an aqueous solution of Quil A: A simple method for the preparation of immune-stimulating complexes
Copland, M. J., Rades, Thomas & Davies, N. M., 10 Mar 2000, In: International Journal of Pharmaceutics. 196, 2, p. 135-139 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Liposomal delivery of antigen to human dendritic cells
Copland, M. J., Baird, M. A., Rades, Thomas, McKenzie, J. L., Becker, B., Reck, F., Tyler, P. C. & Davies, N. M., 14 Feb 2003, In: Vaccine. 21, 9-10, p. 883-890 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Lipid based particulate formulations for the delivery of antigen
Copland, M. J., Rades, Thomas, Davies, N. M. & Baird, M. A., Apr 2005, In: Immunology and Cell Biology. 83, 2, p. 97-105 9 p.Research output: Contribution to journal › Review › Research › peer-review
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Characterization of Amorphous and Co-Amorphous Simvastatin Formulations Prepared by Spray Drying
Craye, G., Löbmann, Korbinian, Grohganz, Holger, Rades, Thomas & Laitinen, R., 2015, In: Molecules. 20, 12, p. 21532-48 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Influence of co-solvents on properties of terpene-based eutectic mixtures: Implications for skin delivery
Czyrski, Grzegorz Sebastian, Rades, Thomas & Heinz, Andrea, 2024, In: International Journal of Pharmaceutics. 664, 15 p., 124615.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Terpene-based eutectic mixtures for cutaneous delivery: Eutectic point vs. molar ratio - which matters more?
Czyrski, Grzegorz Sebastian, Kirkensgaard, Jacob Judas Kain, Rønholt, Stine, Rades, Thomas & Heinz, Andrea, 2024, In: Journal of Molecular Liquids. 411, 13 p., 125726.Research output: Contribution to journal › Journal article › Research › peer-review
Mannosylated saponins based on oleanolic and glycyrrhizic acids. Towards synthetic colloidal antigen delivery systems
Daines, A. M., Greatrex, B. W., Hayman, C. M., Hook, S. M., McBurney, W. T., Rades, Thomas, Rendle, P. M. & Sims, I. M., 2009, In: Bioorganic & Medicinal Chemistry Letters. 17, 14, p. 5207-18 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Editorial: In honor of Professor Ian Tucker
Das, S., Rades, Thomas & McDowell, A., 2023, In: International Journal of Pharmaceutics. 638, 2 p., 122762.Research output: Contribution to journal › Editorial › Research › peer-review
- Published
Understanding the influence of polymorphism on phonon spectra: Lattice dynamics calculations and terahertz spectroscopy of carbamazepine
Day, G. M., Zeitler, J. A., Jones, W., Rades, Thomas & Taday, P. F., 12 Jan 2006, In: Journal of Physical Chemistry B. 110, 1, p. 447-456 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Direct detection of dissolution of <sup>14</sup>C-labeled compounds into an oil phase by the fat scintillation proximity method
De Smidt, P. C. & Rades, Thomas, 2000, In: International Journal of Pharmaceutics.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A comparison of pseudo-ternary diagrams of aqueous mixtures of Quil A, cholesterol and phospholipid prepared by lipid-film hydration and dialysis
Demana, P. H., Davies, N. M., Berger, B., Vosgerau, U. & Rades, Thomas, May 2004, In: Journal of Pharmacy and Pharmacology. 56, 5, p. 573-580 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
Quil A-lipid powder formulations releasing ISCOMs and related colloidal structures upon hydration
Demana, P. H., Davies, N. M., Hook, S. & Rades, Thomas, 2 Mar 2005, In: Journal of controlled release : official journal of the Controlled Release Society. 103, 1, p. 45-59 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
Effect of incorporation of the adjuvant Quil A on structure and immune stimulatory capacity of liposomes
Demana, P. H., Fehske, C., White, K., Rades, Thomas & Hook, S., Oct 2004, In: Immunology and Cell Biology. 82, 5, p. 547-54 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
Analysis of Quil A-phospholipid mixtures using drift spectroscopy
Demana, P. H., Davies, N. M., Hook, S. & Rades, Thomas, 2007, In: International Journal of Pharmaceutics. 342, 1-2, p. 49-61 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
Pseudo-ternary phase diagrams of aqueous mixtures of Quil A, cholesterol and phospholipid prepared by the lipid-film hydration method
Demana, P. H., Davies, N. M., Vosgerau, U. & Rades, Thomas, 11 Feb 2004, In: International Journal of Pharmaceutics. 270, 1-2, p. 229-39 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Incorporation of ovalbumin into ISCOMs and related colloidal particles prepared by the lipid film hydration method
Demana, P. H., Davies, N. M., Berger, B. & Rades, Thomas, 8 Jul 2004, In: International Journal of Pharmaceutics. 278, 2, p. 263-74 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Salt hydrates as a source to form co-amorphous systems when prepared in the absence of water: Hydrogen bond analysis
Deng, Y., Liu, S., Jiang, Y., Grohganz, Holger & Rades, Thomas, 2024, In: Chemical Engineering Science. 296, 120232.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Recent Advances in Co-Former Screening and Formation Prediction of Multicomponent Solid Forms of Low Molecular Weight Drugs
Deng, Y., Liu, S., Jiang, Y., Batista Martins, Inês Catarina & Rades, Thomas, 2023, In: Pharmaceutics. 15, 9, 33 p., 2174.Research output: Contribution to journal › Review › Research › peer-review
- Published
Recent advances in co-amorphous drug formulations
Dengale, S. J., Grohganz, Holger, Rades, Thomas & Löbmann, Korbinian, 1 May 2016, In: Advanced Drug Delivery Reviews. 100, p. 116-125 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Utilizing the allyl-terminated copolymer methoxy(poly(ethylene glycol))-block-poly(jasmine lactone) in the development of amorphous solid dispersions: A comparative study of functionalized and non-functionalized polymer
Di, Rong, Bansal, K. K., Rosenholm, J. M., Grohganz, Holger & Rades, Thomas, 2024, In: International Journal of Pharmaceutics. 657, 12 p., 124175.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Destabilization of Indomethacin-Paracetamol Co-Amorphous Systems by Mechanical Stress
Di, Rong, Grohganz, Holger & Rades, Thomas, 2024, In: Pharmaceutics. 16, 15 p., 67.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Multivariate Approach for the Determination of the Optimal Mixing Ratio of the Non-Strong Interacting Co-Amorphous System Carvedilol-Tryptophan
Di, Rong, Liu, J., Grohganz, Holger & Rades, Thomas, 2021, In: Molecules. 26, 4, 8 p., 801.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of PVP molecular weight on the microwave assisted in situ amorphization of indomethacin
Doreth, M., Löbmann, Korbinian, Priemel, P., Grohganz, Holger, Taylor, R., Holm, R., Lopez de Diego, H. & Rades, Thomas, Jan 2018, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 122, p. 62-69Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glass solution formation in water - In situ amorphization of naproxen and ibuprofen with Eudragit® E PO
Doreth, M., Löbmann, Korbinian, Grohganz, Holger, Holm, R., Lopez De Diego, H., Rades, Thomas & Priemel, P. A., 1 Feb 2016, In: Journal of Drug Delivery Science and Technology. 34, p. 32–40 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Amorphization within the tablet: Using microwave irradiation to form a glass solution in situ
Doreth, M., Hussein, M. A., Priemel, P. A., Grohganz, Holger, Holm, R., Lopez de Diego, H., Rades, Thomas & Löbmann, Korbinian, 15 Mar 2017, In: International Journal of Pharmaceutics. 519, 1-2, p. 343-351 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quantification of microwave-induced amorphization of celecoxib in PVP tablets using transmission Raman spectroscopy
Edinger, M., Knopp, Matthias Manne, Kerdoncuff, H., Rantanen, Jukka, Rades, Thomas & Löbmann, Korbinian, 30 May 2018, In: European Journal of Pharmaceutical Sciences. 117, p. 62-67Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Crystalline adduct of moxifloxacin with trans-cinnamic acid to reduce the aqueous solubility and dissolution rate for improved residence time in the lungs
Eedara, B. B., Tucker, I. G., Zujovic, Z. D., Rades, Thomas, Price, J. R. & Das, S. C., 2019, In: European Journal of Pharmaceutical Sciences. 136, 104961.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The influence of silica nanoparticles on the preparation and stability of O/W emulsions
Eskandar, N. G., Simovic, S., Saupe, A., Rades, Thomas & Prestidge, C. A., 2006, Proceedings of the 2006 International Conference on Nanoscience and Nanotechnology, ICONN.Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review
- Published
Monitoring the intragastric distribution of a colloidal drug carrier model by magnetic resonance imaging460
Faas, H., Schwizer, W., Feinle, C., Lengsfeld, H., De Smidt, C., Boesiger, P., Fried, M. & Rades, Thomas, 2001, In: Pharmaceutical Research.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of meal consistency and ingested fluid volume on the intragastric distribution of a drug model in humans - A magnetic resonance imaging study
Faas, H., Steingoetter, A., Feinle, C., Rades, Thomas, Lengsfeld, H., Boesiger, P., Fried, M. & Schwizer, W., 2002, In: Alimentary Pharmacology and Therapeutics. 16, 2, p. 217-224 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fat digestion modulates gastrointestinal sensations induced by gastric distention and duodenal lipid in humans
Feinle, C., Rades, Thomas, Otto, B. & Fried, M., 2001, In: Gastroenterology.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Acute oral administration of lauric acid reduces energy intake in healthy male
Feltrin, K. L., Brennan, I. M., Rades, Thomas, Horowitz, M. & Feinle-Bisset, C., 2014, In: e - S P E N Journal. 9, 2, p. 69-75 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
Comparative effects of intraduodenal infusions of lauric and oleic acids on antropyloroduodenal motility, plasma cholecystokinin and peptide YY, appetite, and energy intake in healthy men
Feltrin, K. L., Little, T. J., Meyer, J. H., Horowitz, M., Rades, Thomas, Wishart, J. & Feinle-Bisset, C., 2008, In: The American Journal of Clinical Nutrition. 87, 5, p. 1181-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
Effects of lauric acid on upper gut motility, plasma cholecystokinin and peptide YY, and energy intake are load, but not concentration, dependent in humans
Feltrin, K. L., Little, T. J., Meyer, J. H., Horowitz, M., Rades, Thomas, Wishart, J. & Feinle-Bisset, C., 2007, In: Journal of Physiology. 581, Pt 2, p. 767-77 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Effects of intraduodenal fatty acids on appetite, antropyloroduodenal motility, and plasma CCK and GLP-1 in humans vary with their chain length
Feltrin, K. L., Little, T. J., Meyer, J. H., Horowitz, M., Smout, A. J. P. M., Wishart, J., Pilichiewicz, A. N., Rades, Thomas, Chapman, I. M. & Feinle-Bisset, C., Sep 2004, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 287, 3, p. R524-33Research output: Contribution to journal › Journal article › Research › peer-review
Phosphatidyl choline-based colloidal systems for dermal and transdermal drug delivery
Ferderber, K., Hook, S. & Rades, Thomas, 2009, In: Journal of Liposome Research. 19, 4, p. 267-77 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Development of a Video-Microscopic Tool To Evaluate the Precipitation Kinetics of Poorly Water Soluble Drugs: A Case Study with Tadalafil and HPMC
Fjelrad Christfort, J., Christensen, J. P., Madsen, C. M., Nielsen, L. H., Sandau, M., Andersen, K., Mullertz, Anette & Rades, Thomas, 2017, In: Molecular Pharmaceutics. 14, 12, p. 4154-4160Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Solubilisation of soybean oil in microemulsions using various surfactants
Flanagan, J., Kortegaard, K., Neil Pinder, D., Rades, Thomas & Singh, H., Mar 2006, In: Food Hydrocolloids. 20, 2-3 SPEC. ISS., p. 253-260 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Subunit Vaccine Delivery: Advances in Delivery Science and Technology
Foged, Camilla, Rades, Thomas, Perrie, Y. & Hook, S., 2015, New York.Research output: Book/Report › Book › Research › peer-review
- Published
Distribution of binder in granules produced by means of twin screw granulation
Fonteyne, M., Fussell, A. L., Vercruysse, J., Vervaet, C., Remon, J. P., Strachan, C., Rades, Thomas & De Beer, T., 28 Feb 2014, In: International Journal of Pharmaceutics. 462, 1-2, p. 8-10 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparison of the Gordon-Taylor and Couchman-Karasz equations for prediction of the glass transition temperature of glass solutions of drug and polyvinylpyrrolidone prepared by melt extrusion
Forster, A., Hempenstall, J. & Rades, Thomas, Nov 2003, In: Pharmazie. 58, 11, p. 838-839 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Investigation of the physical stability of amorphous drug and drug/polymer melts using variable temperature solid state NMR
Forster, A., Apperley, D., Hempenstall, J., Lancaster, R. & Rades, Thomas, Oct 2003, In: Pharmazie. 58, 10, p. 761-762 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Selection of excipients for melt extrusion with two poorly water-soluble drugs by solubility parameter calculation and thermal analysis
Forster, A., Hempenstall, J., Tucker, I. & Rades, Thomas, 11 Sep 2001, In: International Journal of Pharmaceutics. 226, 1-2, p. 147-161 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The potential of small-scale fusion experiments and the Gordon-Taylor equation to predict the suitability of drug/polymer blends for melt extrusion
Forster, A., Hempenstall, J., Tucker, I. & Rades, Thomas, 2001, In: Drug Development and Industrial Pharmacy.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of glass solutions of poorly water-soluble drugs produced by melt extrusion with hydrophilic amorphous polymers
Forster, A., Hempenstall, J. & Rades, Thomas, 2001, In: Journal of Pharmacy and Pharmacology.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Selection of suitable drug and excipient candidates to prepare glass solutions by melt extrusion for immediate release oral formulations
Forster, A., Rades, Thomas & Hempenstall, J., 1 Oct 2002, In: Pharmaceutical Technology Europe. 14, 10, p. 27-28+31Research output: Contribution to journal › Review › Research › peer-review
- Published
Report from working group on developing a communication and PR strategy for the Department of Pharmacy, Copenhagen University
Gammelgaard, Bente, Rades, Thomas, K, H., Nørgaard, Lotte Stig & Nielsen, C. U., Oct 2012, Rapport fra arbejdsgruppe nedsat mhp. etablering af kommunikations- og PR-strategi for Institut for Farmaci. 15 p.Research output: Chapter in Book/Report/Conference proceeding › Report chapter › Commissioned
- Published
Mathematical modeling of drug release from Eudragit RS-based delivery systems
Glaessl, B., Siepmann, F., Tucker, I., Rades, Thomas & Siepmann, J., 2010, In: Journal of Drug Delivery Science and Technology. 20, 2, p. 127-133 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Deeper insight into the drug release mechanisms in Eudragit RL-based delivery systems
Glaessl, B., Siepmann, F., Tucker, I., Rades, Thomas & Siepmann, J., 15 Apr 2010, In: International Journal of Pharmaceutics. 389, 1-2, p. 139-146 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterisation of quaternary polymethacrylate films containing tartaric acid, metoprolol free base or metoprolol tartrate
Glaessl, B., Siepmann, F., Tucker, I., Siepmann, J. & Rades, Thomas, 2009, In: European Journal of Pharmaceutics and Biopharmaceutics.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The influence of co-formers on the dissolution rates of co-amorphous sulfamerazine/excipient systems
Gniado, K., Löbmann, Korbinian, Rades, Thomas & Erxleben, A., 17 May 2016, In: International Journal of Pharmaceutics. 504, 1-2, p. 20-6 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The use of quantum chemistry in pharmaceutical research as illustrated by case studies of indometacin and carbamazepine
Gordon, K. C., McGoverin, C. M., Strachan, C. J. & Rades, Thomas, 2007, In: Journal of Pharmacy and Pharmacology. 59, 2, p. 271-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Chitosan hydrogels containing liposomes and cubosomes as particulate sustained release vaccine delivery systems
Gordon, S., Young, K., Wilson, R., Rizwan, S., Kemp, R., Rades, Thomas & Hook, S., Sep 2012, In: Journal of Liposome Research. 22, 3, p. 193-204 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparison of chitosan nanoparticles and chitosan hydrogels for vaccine delivery
Gordon, S., Saupe, A., McBurney, W., Rades, Thomas & Hook, S., 2008, In: Journal of Pharmacy and Pharmacology. 60, 12, p. 1591-600 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Applying thermodynamic and kinetic parameters to predict the physical stability of two differently prepared amorphous forms of simvastatin
Graeser, K. A., Patterson, J. E. & Rades, Thomas, 2009, In: Current Drug Delivery. 6, 4, p. 374-82 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Correlating thermodynamic and kinetic parameters with amorphous stability
Graeser, K. A., Patterson, J. E., Zeitler, J. A., Gordon, K. C. & Rades, Thomas, 2009, In: European Journal of Pharmaceutical Sciences. 37, 3-4, p. 492-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The role of configurational entropy in amorphous systems
Graeser, K. A., Patterson, J. E., Zeitler, J. A. & Rades, Thomas, Jun 2010, In: Pharmaceutics. 2, 2, p. 224-244 21 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Physicochemical properties and stability of two differently prepared amorphous forms of simvastatin
Graeser, K. A., Strachan, C. J., Patterson, J. E., Gordon, K. C. & Rades, Thomas, Jan 2008, In: Crystal Growth and Design. 8, 1, p. 128-135 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
Protein delivery using nanoparticles based on microemulsions with different structure-types
Graf, A., Jack, K. S., Whittaker, A. K., Hook, S. M. & Rades, Thomas, 2008, In: European Journal of Pharmaceutical Sciences. 33, 4-5, p. 434-44 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Oral insulin delivery using nanoparticles based on microemulsions with different structure-types: optimisation and in vivo evaluation
Graf, A., Rades, Thomas & Hook, S. M., 2009, In: European Journal of Pharmaceutical Sciences. 37, 1, p. 53-61 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Poly(Alkyl Cyanoacrylate) nanoparticles for drug delivery and vaccine development
Graf, A., Krauel-Göllner, K. & Rades, Thomas, 19 Apr 2016, Colloids in Drug Delivery. CRC Press, p. 99-136 38 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
Microemulsions containing lecithin and sugar-based surfactants: nanoparticle templates for delivery of proteins and peptides
Graf, A., Ablinger, E., Peters, S., Zimmer, A., Hook, S. & Rades, Thomas, 2008, In: International Journal of Pharmaceutics. 350, 1-2, p. 351-60 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Poly(alkylcyanoacrylate) nanoparticles for enhanced delivery of therapeutics - is there real potential?
Graf, A., McDowell, A. & Rades, Thomas, 2009, In: Expert Opinion on Drug Delivery. 6, 4, p. 371-87 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The synthesis and immune stimulating action of mannose-capped lysine-based dendrimers
Greatrex, B. W., Brodie, S. J., Furneaux, R. H., Hook, S. M., McBurney, W. T., Painter, G. F., Rades, Thomas & Rendle, P. M., 11 Apr 2009, In: Tetrahedron. 65, 15, p. 2939-2950 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Synthesis, Formulation, and Adjuvanticity of Monodesmosidic Saponins with Olenanolic Acid, Hederagenin and Gypsogenin Aglycones, and some C-28 Ester Derivatives
Greatrex, B. W., Daines, A. M., Hook, S., Lenz, D. H., McBurney, W., Rades, Thomas & Rendle, P. M., Dec 2015, In: ChemistryOpen. 4, 6, p. 740-755 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Amorphous drugs and dosage forms
Grohganz, Holger, Löbmann, Korbinian, Priemel, P., Tarp Jensen, K., Graeser, K., Strachan, C. & Rades, Thomas, 2013, In: Journal of Drug Delivery Science and Technology.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Amorphous drugs and dosage forms
Grohganz, Holger, Löbmann, Korbinian, Priemel, P., Jensen, K. B. T., Graeser, K., Strachan, C. & Rades, Thomas, 1 Jul 2013, In: Journal of Drug Delivery Science and Technology. 23, 4, p. 403-408 6 p.Research output: Contribution to journal › Review › Research
- Published
Refining stability and dissolution rate of amorphous drug formulations
Grohganz, Holger, Priemel, P. A., Löbmann, Korbinian, Nielsen, L. H., Laitinen, R., Mullertz, Anette , Van den Mooter, G. & Rades, Thomas, Jun 2014, In: Expert Opinion on Drug Delivery. 11, 6, p. 977-89 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Electrospun fibers for the treatment of skin diseases
Gürtler, Anna-Lena, Rades, Thomas & Heinz, Andrea, 2023, In: Journal of controlled release : official journal of the Controlled Release Society. 363, p. 621-640Research output: Contribution to journal › Review › Research › peer-review
- Published
Advancing inflammatory skin disease therapy: Sustained tofacitinib release via electrospun fiber dressings
Gürtler, Anna-Lena, Maltschik, A. M., Meryem Güler Yildiz, S., Vangelofski, K., Sørensen, Luna Gade, Grohganz, Holger, Rades, Thomas & Heinz, Andrea, 2024, In: European Journal of Pharmaceutics and Biopharmaceutics. 202, 8 p., 114423.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Electrospun dressings with a dual release functionality of two anti-inflammatory active ingredients
Gürtler, Anna-Lena, Sirois, J. P., Lang, J. C., Melican, K., Rades, Thomas & Heinz, Andrea, 2024, In: RSC Pharmaceutics. 1, p. 570-580Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Application of terahertz pulsed imaing to analyse film coating characteristics of sustained-release coated pellets
Haaser, M., Karrout, Y., Velghe, C., Cuppok, Y., Gordon, K. C., Pepper, M., Siepmann, J., Rades, Thomas, Taday, P. F. & Strachan, C. J., 2013, In: International Journal of Pharmaceutics. 457, 2, p. 521-526Research output: Contribution to journal › Journal article › Research › peer-review
Analysis of matrix dosage forms during dissolution testing using raman microscopy
Haaser, M., Windbergs, M., McGoverin, C. M., Kleinebudde, P., Rades, Thomas, Gordon, K. C. & Strachan, C. J., 2011, In: Al Azhar Journal of Pharmaceutical Sciences.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evaluating the effect of coating equipment on tablet film quality using terahertz pulsed imaging
Haaser, M., Naelapaa, K., Gordon, K. C., Pepper, M., Rantanen, Jukka, Strachan, C. J., Taday, P. F., Zeitler, J. A. & Rades, Thomas, Nov 2013, In: European Journal of Pharmaceutics and Biopharmaceutics. 85, 3 Pt B, p. 1095-102 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Terahertz pulsed imaging as an advanced characterisation tool for film coatings--a review
Haaser, M., Gordon, K. C., Strachan, C. J. & Rades, Thomas, 5 Dec 2013, In: International Journal of Pharmaceutics. 457, 2, p. 510-20 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dissolution properties of co-amorphous drug-amino acid formulations in buffer and biorelevant media
Heikkinen, A. T., DeClerck, L., Löbmann, Korbinian, Grohganz, Holger, Rades, Thomas & Laitinen, R., Jul 2015, In: Pharmazie. 70, 7, p. 452-457 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterizing an amorphous system exhibiting trace crystallinity: A case study with saquinavir
Heinz, Andrea, Strachan, C. J., Atassi, F., Gordon, K. C. & Rades, Thomas, Jan 2008, In: Crystal Growth & Design. 8, 1, p. 119-127Research output: Contribution to journal › Journal article › Research › peer-review
Understanding the solid-state forms of fenofibrate - a spectroscopic and computational study
Heinz, Andrea, Gordon, K. C., McGoverin, C. M., Rades, Thomas & Strachan, C. J., 2009, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 71, 1, p. 100-108Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Analysis of solid-state transformations of pharmaceutical compounds using vibrational spectroscopy
Heinz, Andrea, Strachan, C. J., Gordon, K. C. & Rades, Thomas, Aug 2009, In: The Journal of pharmacy and pharmacology. 61, 8, p. 971-88 18 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Quantifying ternary mixtures of different solid-state forms of indomethacin by Raman and near-infrared spectroscopy
Heinz, Andrea, Savolainen, M., Rades, Thomas & Strachan, C. J., 2007, In: European Journal of Pharmaceutical Sciences. 32, 3, p. 182-192 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Analysis of sustained-release tablet film coats using terahertz pulsed imaging
Ho, L., Müller, R., Römer, M., Gordon, K. C., Heinämäki, J., Kleinebudde, P., Pepper, M., Rades, Thomas, Shen, Y. C., Strachan, C. J., Taday, P. F. & Zeitler, J. A., 22 Jun 2007, In: Journal of Controlled Release. 119, 3, p. 253-261 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Terahertz pulsed imaging as an analytical tool for tablet coating quality
Ho, L., Müller, R., Römer, M., Gordon, K. C., Heinämäki, J., Kleinebudde, P., Pepper, M., Rades, Thomas, Shen, Y. C., Strachan, C. J., Taday, P. F. & Zeitler, J. A., 2007, IRMMW-THz2007 - Conference Digest of the Joint 32nd International Conference on Infrared and Millimetre Waves, and 15th International Conference on Terahertz Electronics.Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review
Effects of film coating thickness and drug layer uniformity on in vitro drug release from sustained-release coated pellets: a case study using terahertz pulsed imaging
Ho, L., Cuppok, Y., Muschert, S., Gordon, K. C., Pepper, M., Shen, Y., Siepmann, F., Siepmann, J., Taday, P. F. & Rades, Thomas, 2009, In: International Journal of Pharmaceutics. 382, 1-2, p. 151-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Investigating dissolution performance critical areas on coated tablets: a case study using terahertz pulsed imaging
Ho, L., Müller, R., Krüger, C., Gordon, K. C., Kleinebudde, P., Pepper, M., Rades, Thomas, Shen, Y., Taday, P. F. & Zeitler, J. A., 2010, In: Al Azhar Journal of Pharmaceutical Sciences. 99, 1, p. 392-402 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Applications of terahertz pulsed imaging to sustained-release tablet film coating quality assessment and dissolution performance
Ho, L., Müller, R., Gordon, K. C., Kleinebudde, P., Pepper, M., Rades, Thomas, Shen, Y., Taday, P. F. & Zeitler, J. A., 2008, In: Journal of controlled release : official journal of the Controlled Release Society. 127, 1, p. 79-87 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Terahertz pulsed imaging as an analytical tool for sustained-release tablet film coating
Ho, L., Müller, R., Gordon, K. C., Kleinebudde, P., Pepper, M., Rades, Thomas, Shen, Y., Taday, P. F. & Zeitler, J. A., 2009, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 71, 1, p. 117-23 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
Monitoring the film coating unit operation and predicting drug dissolution using terahertz pulsed imaging
Ho, L., Müller, R., Gordon, K. C., Kleinebudde, P., Pepper, M., Rades, Thomas, Shen, Y., Taday, P. F. & Zeitler, J. A., 2009, In: Al Azhar Journal of Pharmaceutical Sciences. 98, 12, p. 4866-76 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mechanochemical activated dry amorphisation by milling equilibrium between ap mesoporous silica
Hoefer, H. H., Monsuur, F. H., Pauly, T., Choudhari, Y., Löbmann, Korbinian & Rades, Thomas, 2019, Patent No. US20190350855A1Research output: Patent
- Published
(Co-)amorphization of enantiomers – Investigation of the amorphization process, the physical stability and the dissolution behavior
Holzapfel, K., Liu, J., Rades, Thomas & Leopold, C. S., 2022, In: International Journal of Pharmaceutics. 616, 9 p., 121552.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Co-amorphous systems consisting of indomethacin and the chiral co-former tryptophan: Solid-state properties and molecular mobilities
Holzapfel, K., Rades, Thomas & Leopold, C. S., 2023, In: International Journal of Pharmaceutics. 636, 12 p., 122840.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Immune stimulating complexes (ISCOMs) and Quil-A containing particulate formulations as vaccine delivery systems
Hook, S. & Rades, Thomas, 1 Jan 2013, Immunomic Discovery of Adjuvants and Candidate Subunit Vaccines. Springer New York, p. 233-261 29 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Physical Characterization of Synthetic Phosphatidylinositol Dimannosides and Analogues in Binary Systems with Phosphatidylcholine
Hubert, M., Larsen, D. S., Hayman, C. M., Rades, Thomas & Hook, S., 30 Jan 2014, In: Molecular Pharmaceutics. 11, 3, p. 913-921 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Physicochemical and biological characterization of synthetic phosphatidylinositol dimannosides and analogues
Hubert, M., Compton, B. J., Hayman, C. M., Larsen, D. S., Painter, G. F., Rades, Thomas & Hook, S., 6 May 2013, In: Molecular Pharmaceutics. 10, 5, p. 1928-39 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Formation mechanism of coamorphous drug−amino acid mixtures
Jensen, K. B. T., Larsen, F. H., Cornett, Claus, Löbmann, Korbinian, Grohganz, Holger & Rades, Thomas, 2015, In: Molecular Pharmaceutics. 12, 7, p. 2484−2492 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Improving co-amorphous drug formulations by the addition of the highly water soluble amino acid proline
Jensen, K. B. T., Löbmann, Korbinian, Rades, Thomas & Grohganz, Holger, 2014, In: Pharmaceutics. 6, 3, p. 416-435 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of variation in molar ratio on co-amorphous drug-amino acid systems
Jensen, K. B. T., Larsen, F. H., Löbmann, Korbinian, Rades, Thomas & Grohganz, Holger, 2016, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 107, p. 32-39 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Preparation and characterization of spray-dried co-amorphous drug-amino acid salts
Jensen, K. B. T., Blaabjerg, L. I., Lenz, E., Bohr, A., Grohganz, Holger, Kleinebudde, P., Rades, Thomas & Löbmann, Korbinian, May 2016, In: The Journal of pharmacy and pharmacology. 68, 5, p. 615–624 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Amorphous is not always better—A dissolution study on solid state forms of carbamazepine
Jensen, L. G., Skautrup, F. B., Mullertz, Anette , Abrahamsson, B., Rades, Thomas & Priemel, P. A., 30 Apr 2017, In: International Journal of Pharmaceutics. 522, 1-2, p. 74-79 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of the hydrodynamics in a miniaturized dissolution apparatus
Johansson, Kristoffer Enøe, Plum, J., Mosleh, M., Madsen, C. M., Rades, Thomas & Mullertz, Anette , 2018, In: Journal of Pharmaceutical Sciences. 107, 4, p. 1095-1103 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Themed issue: Applications of novel spectroscopic techniques to pharmaceutical systems
Jones, D. S. & Rades, Thomas, Feb 2007, In: Journal of Pharmacy and Pharmacology. 59, 2, p. 145-146 2 p.Research output: Contribution to journal › Editorial › Research › peer-review
- Published
Exploring the utility of the Chasing-rinciple: influence of drug-free SNEDDS composition on solubilization of carvedilol, cinnarizine and R3040 in aqueous suspension
Jorgensen, S. D. S., Rades, Thomas, Mu, Huiling, Graeser, K. & Mullertz, Anette , Jan 2019, In: Acta Pharmaceutica Sinica B. 9, 1, p. 194-201Research output: Contribution to journal › Letter › Research › peer-review
- Published
The ability of two in vitro lipolysis models reflecting the human and rat gastro-intestinal conditions to predict the in vivo performance of SNEDDS dosing regimens
Jorgensen, S. D. S., Al Sawaf, M., Graeser, K., Mu, Huiling, Mullertz, Anette & Rades, Thomas, Mar 2018, In: European Journal of Pharmaceutics and Biopharmaceutics. 124, p. 116-124Research output: Contribution to journal › Journal article › Research › peer-review
Aerosol OT microemulsions as carriers for transdermal delivery of hydrophobic and hydrophilic local anesthetics
Junyaprasert, V. B., Boonme, P., Wurster, D. E. & Rades, Thomas, 2008, In: Drug Delivery Technology. 15, 5, p. 323-30 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transdermal delivery of hydrophobic and hydrophilic local anesthetics from o/w and w/o Brij 97-based microemulsions
Junyaprasert, V. B., Boonme, P., Songkro, S., Krauel, K. & Rades, Thomas, 2007, In: Journal of Pharmacy and Pharmaceutical Sciences. 10, 3, p. 288-98 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Design of a self-unfolding delivery concept for oral administration of macromolecules
Jørgensen, J. R., Thamdrup, L. H. E., Kamguyan, K., Nielsen, L. H., Nielsen, Hanne Mørck, Boisen, A., Rades, Thomas & Mullertz, Anette , 2021, In: Journal of Controlled Release. 329, p. 948-954Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In vitro-in vivo relationship for amorphous solid dispersions using a double membrane dissolution-permeation setup
Jørgensen, J. R., Mohr, W., Rischer, M., Sauer, A., Mistry, S., Rades, Thomas & Mullertz, Anette , 2023, In: European Journal of Pharmaceutics and Biopharmaceutics. 188, p. 26-32Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Stability and intrinsic dissolution of vacuum compression molded amorphous solid dispersions of efavirenz
Jørgensen, J. R., Mohr, W., Rischer, M., Sauer, A., Mistry, S., Mullertz, Anette & Rades, Thomas, 2023, In: International Journal of Pharmaceutics. 632, 8 p., 122564.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In Vitro, Ex Vivo and In Vivo Evaluation of Microcontainers for Oral Delivery of Insulin
Jørgensen, J. R., Yu, F., Ramakrishnan, V., Nielsen, L. H., Nielsen, Hanne Mørck, Boisen, A., Rades, Thomas & Mullertz, Anette , 7 Jan 2020, In: Pharmaceutics. 12, 1, 14 p., 48.Research output: Contribution to journal › Journal article › Research › peer-review
Characterization of Peptide Polymer Interactions in Poly(alkylcyanoacrylate) Nanoparticles: A Mass Spectrometric Approach
Kafka, A. P., Kleffmann, T., Rades, Thomas & McDowell, A., 2010, In: Current Drug Delivery.Research output: Contribution to journal › Journal article › Research › peer-review
The application of MALDI TOF MS in biopharmaceutical research
Kafka, A. P., Kleffmann, T., Rades, Thomas & McDowell, A., 2011, In: International Journal of Pharmaceutics. 417, 1-2, p. 70-82 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
Release and bioactivity of PACA nanoparticles containing D-Lys6-GnRH for brushtail possum fertility control
Kafka, A. P., McLeod, B. J., Rades, Thomas & McDowell, A., 2011, In: Journal of controlled release : official journal of the Controlled Release Society. 149, 3, p. 307-13 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rapid and specific high-performance liquid chromatography for the in vitro quantification of D-Lys6-GnRH in a microemulsion-type formulation in the presence of peptide oxidation products
Kafka, A. P., Rades, Thomas & McDowell, A., Feb 2010, In: Biomedical Chromatography. 24, 2, p. 132-139 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Histidine residues in the peptide D-Lys6-GnRH: Potential for copolymerization in polymeric nanoparticles
Kafka, A. P., Kleffmann, T., Rades, Thomas & McDowell, A., 5 Oct 2009, In: Molecular Pharmaceutics. 6, 5, p. 1483-1491 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lysozyme-magnesium aluminum silicate microparticles: Molecular interaction, bioactivity and release studies
Kanjanakawinkul, W., Medlicott, N. J., Rades, Thomas, Puttipipatkhachorn, S. & Pongjanyakul, T., Sep 2015, In: International Journal of Biological Macromolecules. 80, p. 651-658 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nicotine-magnesium aluminum silicate microparticle surface modified with chitosan for mucosal delivery
Kanjanakawinkul, W., Rades, Thomas, Puttipipatkhachorn, S. & Pongjanyakul, T., 1 Apr 2013, In: Materials science & engineering. C, Materials for biological applications. 33, 3, p. 1727-36 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Measurement of amorphous indomethacin stability with NIR and Raman spectroscopy
Kao, J. Y., McGoverin, C. M., Graeser, K. A., Rades, Thomas & Gordon, K. C., Jan 2012, In: Vibrational Spectroscopy. 58, p. 19-26 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Determining Thermal Conductivity of Small Molecule Amorphous Drugs with Modulated Differential Scanning Calorimetry and Vacuum Molding Sample Preparation
Karl, M., Rantanen, Jukka & Rades, Thomas, 6 Dec 2019, In: Pharmaceutics. 11, 12, 7 p., 670.Research output: Contribution to journal › Journal article › Communication
- Published
Temperature-Modulated Micromechanical Thermal Analysis with Microstring Resonators Detects Multiple Coherent Features of Small Molecule Glass Transition
Karl, M., Thamdrup, L. H. E., Rantanen, Jukka, Boisen, A. & Rades, Thomas, 2020, In: Sensors. 20, 4, 14 p., 1019.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ultra Sensitive Micro String Resonators for Solid State Thermomechanical Analysis of Small and Large Molecules
Karl, M., Larsen, P. E., Rangacharya, V., Hwu, E. T., Rantanen, Jukka, Boisen, A. & Rades, Thomas, 19 Dec 2018, In: Journal of the American Chemical Society. 140, 50, p. 17522-17531Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of different preparation methods on the dissolution behaviour of amorphous indomethacin
Karmwar, P., Graeser, K., Gordon, K. C., Strachan, C. J. & Rades, Thomas, Feb 2012, In: European Journal of Pharmaceutics and Biopharmaceutics. 80, 2, p. 459-464 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Investigation of properties and recrystallisation behaviour of amorphous indomethacin samples prepared by different methods
Karmwar, P., Graeser, K., Gordon, K. C., Strachan, C. J. & Rades, Thomas, 30 Sep 2011, In: International Journal of Pharmaceutics. 417, 1-2, p. 94-100 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Process Optimization and Upscaling of Spray-Dried Drug-Amino acid Co-Amorphous Formulations
Kasten, G., Duarte, Í., Paisana, M., Löbmann, Korbinian, Rades, Thomas & Grohganz, Holger, 9 Jan 2019, In: Pharmaceutics. 11, 1, 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In vitro and in vivo comparison between crystalline and co-amorphous salts of naproxen-arginine
Kasten, G., Lobo, L., Dengale, S., Grohganz, Holger, Rades, Thomas & Löbmann, Korbinian, 1 Nov 2018, In: European Journal of Pharmaceutics and Biopharmaceutics. 132, p. 192-199 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Development of a screening method for co-amorphous formulations of drugs and amino acids
Kasten, G., Grohganz, Holger, Rades, Thomas & Löbmann, Korbinian, Dec 2016, In: European Journal of Pharmaceutical Sciences. 95, p. 28-35 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Performance comparison between crystalline and co-amorphous salts of indomethacin-lysine
Kasten, G., Nouri, K., Grohganz, Holger, Rades, Thomas & Löbmann, Korbinian, 25 Nov 2017, In: International Journal of Pharmaceutics. 533, 1, p. 138-144 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Co-former selection for co-amorphous drug-amino acid formulations
Kasten, G., Löbmann, Korbinian, Grohganz, Holger & Rades, Thomas, 2019, In: International Journal of Pharmaceutics. 557, p. 366-373Research output: Contribution to journal › Journal article › Research › peer-review
Development of a novel magnetic resonance imaging contrast agent for pressure measurements using lipid-coated microbubbles
Kaur, R., Morris, R., Bencsik, M., Vangala, A., Rades, Thomas & Perrie, Y., 2009, In: Journal of Biomedical Nanotechnology. 5, 6, p. 707-15 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Precipitation Behavior of Poorly Water-Soluble Drugs with an Emphasis on the Digestion of Lipid Based Formulations
Khan, J., Rades, Thomas & Boyd, B., Mar 2016, In: Pharmaceutical Research. 33, 3, p. 548-62 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In Situ Lipolysis and Synchrotron Small-Angle X-ray Scattering for the Direct Determination of the Precipitation and Solid-State Form of a Poorly Water-Soluble Drug During Digestion of a Lipid-Based Formulation
Khan, J., Hawley, A., Rades, Thomas & Boyd, B. J., Sep 2016, In: Journal of Pharmaceutical Sciences. 105, 9, p. 2631-2639 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Addition of Cationic Surfactants to Lipid-Based Formulations of Poorly Water-Soluble Acidic Drugs Alters the Phase Distribution and the Solid-State Form of the Precipitate Upon In Vitro Lipolysis
Khan, J., Rades, Thomas & Boyd, Ben, Sep 2018, In: Journal of Pharmaceutical Sciences. 107, 9, p. 2420-2427 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lipid-Based Formulations Can Enable the Model Poorly Water-Soluble Weakly Basic Drug Cinnarizine to Precipitate in an Amorphous-Salt Form during in Vitro Digestion
Khan, J., Rades, Thomas & Boyd, B. J., 2016, In: Molecular Pharmaceutics. 13, 11, p. 3783-3793 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Development and characterization of clove oil nanoemulsions and self-microemulsifying drug delivery systems
Kheawfu, K., Pikulkaew, S., Rades, Thomas, Mullertz, Anette & Okonogi, S., 2018, In: Journal of Drug Delivery Science and Technology. 46, p. 330-338 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Elucidating Pathway and Anesthetic Mechanism of Action of Clove Oil Nanoformulations in Fish
Kheawfu, K., Pikulkaew, S., Wellendorph, Petrine, Jørgensen, Louise von Gersdorff, Rades, Thomas, Mullertz, Anette & Okonogi, S., 2022, In: Pharmaceutics. 14, 5, 13 p., 919.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Design and optimization of self-nanoemulsifying drug delivery systems of clove oil for efficacy enhancement in fish anesthesia
Kheawfu, Pikulkaew, Rades, Thomas, Mullertz, Anette , Jørgensen, Louise von Gersdorff & Okonogi, 2021, In: Journal of Drug Delivery Science and Technology. 61, 9 p., 102241.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of preparation method and choice of phospholipid on co-amorphization, physical stability, and dissolution behavior of equimolar indomethacin-phospholipid systems: A case study
Khorami, Keyoomars, Mullertz, Anette & Rades, Thomas, 2024, In: Journal of Drug Delivery Science and Technology. 93, 8 p., 105433.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Binding of Alpinia galanga Oil and Its Nanoemulsion to Mammal GABA(A) Receptors Using Rat Cortical Membranes and an In Silico Modeling Platform
Khumpirapang, N., Suknuntha, K., Wongrattanakamon, P., Jiranusornkul, S., Anuchapreeda, S., Wellendorph, Petrine, Mullertz, Anette , Rades, Thomas & Okonogi, S., 2022, In: Pharmaceutics. 14, 3, 15 p., 650.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Formulation optimization, anesthetic activity, skin permeation, and transportation pathway of Alpinia galanga oil SNEDDS in zebrafish (Danio rerio)
Khumpirapang, N., Jørgensen, Louise von Gersdorff, Mullertz, Anette , Rades, Thomas & Okonogi, S., 2021, In: European Journal of Pharmaceutics and Biopharmaceutics. 165, p. 193-202 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Self-microemulsifying drug delivery system and nanoemulsion for enhancing aqueous miscibility of Alpinia galanga oil
Khumpirapang, N., Pikulkaew, S., Mullertz, Anette , Rades, Thomas & Okonogi, S., 2017, In: PLOS ONE. 12, 11, 18 p., e0188848.Research output: Contribution to journal › Journal article › Research › peer-review
Chitosan-magnesium aluminum silicate nanocomposite films: physicochemical characterization and drug permeability
Khunawattanakul, W., Puttipipatkhachorn, S., Rades, Thomas & Pongjanyakul, T., 2010, In: International Journal of Pharmaceutics. 393, 1-2, p. 219-29 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Chitosan-magnesium aluminum silicate composite dispersions: characterization of rheology, flocculate size and zeta potential
Khunawattanakul, W., Puttipipatkhachorn, S., Rades, Thomas & Pongjanyakul, T., 2008, In: International Journal of Pharmaceutics. 351, 1-2, p. 227-35 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Novel chitosan-magnesium aluminum silicate nanocomposite film coatings for modified-release tablets
Khunawattanakul, W., Puttipipatkhachorn, S., Rades, Thomas & Pongjanyakul, T., 2011, In: International Journal of Pharmaceutics. 407, 1-2, p. 132-41 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Determination of Stable Co-Amorphous Drug-Drug Ratios from the Eutectic Behavior of Crystalline Physical Mixtures
Kissi, E. O., Khorami, Keyoomars & Rades, Thomas, 2019, In: Pharmaceutics. 11, 11 p., 628.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterising glass transition temperatures and glass dynamics in mesoporous silica-based amorphous drugs
Kissi, E. O., Ruggiero, M. T., Hempel, N. J., Song, Z., Grohganz, Holger, Rades, Thomas & Löbmann, Korbinian, 1 Jan 2019, In: Physical Chemistry Chemical Physics. 21, 35, p. 19686-19694 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glass-Transition Temperature of the β-Relaxation as the Major Predictive Parameter for Recrystallization of Neat Amorphous Drugs
Kissi, E. O., Grohganz, Holger, Löbmann, Korbinian, Ruggiero, M. T., Zeitler, J. A. & Rades, Thomas, 15 Mar 2018, In: Journal of Physical Chemistry Part B: Condensed Matter, Materials, Surfaces, Interfaces & Biophysical. 122, 10, p. 2803-2808 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Role of Glass Transition Temperatures in Coamorphous Drug-Amino Acid Formulations
Kissi, E. O., Kasten, G., Löbmann, Korbinian, Rades, Thomas & Grohganz, Holger, 4 Sep 2018, In: Molecular Pharmaceutics. 15, 9, p. 4247–4256Research output: Contribution to journal › Journal article › Research › peer-review
- Published
X-ray Imaging for Gastrointestinal Tracking of Microscale Oral Drug Delivery Devices
Kjeldsen, R. B., Kristensen, M. N., Gundlach, C., Thamdrup, L. H. E., Mullertz, Anette , Rades, Thomas, Nielsen, L. H., Zór, K. & Boisen, A., 2021, In: ACS Biomaterials Science and Engineering. 7, 6, p. 2538–2547Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Assessing acute colitis induced by dextran sulfate sodium in rats and its impact on gastrointestinal fluids
Klitgaard, Mette, Kristensen, M. N., Venkatasubramanian, R., Guerra, Priscila Regina, Jacobsen, Jette, Berthelsen, R., Rades, Thomas & Mullertz, Anette , 2023, In: Drug Delivery and Translational Research. 13, p. 1484–1499Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhalable Antimicrobials for Treatment of Bacterial Biofilm-Associated Sinusitis in Cystic Fibrosis Patients: Challenges and Drug Delivery Approaches
Klodzinska, S. N., Priemel, P. A., Rades, Thomas & Nielsen, Hanne Mørck, 9 Oct 2016, In: International Journal of Molecular Sciences . 17, 10, 19 p., 1688.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Combining diagnostic methods for antimicrobial susceptibility testing – A comparative approach
Klodzinska, S. N., Priemel, P. A., Rades, Thomas & Nielsen, Hanne Mørck, Jan 2018, In: Journal of Microbiological Methods. 144, p. 177-185Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Multispectral UV imaging for fast and non-destructive quality control of chemical and physical tablet attributes
Klukkert, M., Wu, J. X., Rantanen, Jukka, Carstensen, J. M., Rades, Thomas & Leopold, C. S., 2016, In: European Journal of Pharmaceutical Sciences. 90, p. 85-95 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rapid Assessment of Tablet Film Coating Quality by Multispectral UV Imaging
Klukkert, M., Wu, J. X., Rantanen, Jukka, Rehder, S., Carstensen, J. M., Rades, Thomas & Leopold, C. S., 13 Oct 2015, In: AAPS PharmSciTech. p. 1-10 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Non-destructive Quality control of tablets and blister packs by UV imaging
Klukkert, M., Wu, J. X., Rantanen, Jukka, Rehder, S., Carstensen, J. M., Rades, Thomas & Leopold, C. S., 2016, In: Pharmazeutische Industrie. 78, 1, p. 108-120 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of Tableting on the Conformation and Thermal Stability of Trypsin as a Model Protein
Klukkert, M., van de Weert, Marco, Fanø, M., Rades, Thomas & Leopold, C. S., 2015, In: Journal of Pharmaceutical Sciences. 104, 12, p. 4314–4321 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of amorphous phase separation and crystallization on the in vitro and in vivo performance of an amorphous solid dispersion
Knopp, Matthias Manne, Wendelboe, J., Holm, R. & Rades, Thomas, Sep 2018, In: European Journal of Pharmaceutics and Biopharmaceutics. 130, p. 290-295Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Recent advances and potential applications of modulated differential scanning calorimetry (mDSC) in drug development
Knopp, Matthias Manne, Löbmann, Korbinian, Elder, D. P., Rades, Thomas & Holm, R., 1 May 2016, In: European Journal of Pharmaceutical Sciences. 87, p. 164-173 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of Polymer Molecular Weight on Drug-Polymer Solubility: A Comparison between Experimentally Determined Solubility in PVP and Prediction Derived from Solubility in Monomer
Knopp, Matthias Manne, Olesen, N. E., Holm, P., Langguth, P., Holm, R. & Rades, Thomas, 3 Mar 2015, In: Journal of Pharmaceutical Sciences. 104, 9, p. 2905–2912 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of Copolymer Composition on In Vitro and In Vivo Performance of Celecoxib-PVP/VA Amorphous Solid Dispersions
Knopp, Matthias Manne, Nguyen, J. H., Mu, Huiling, Langguth, P., Rades, Thomas & Holm, R., Mar 2016, In: The A A P S Journal. 18, 2, p. 416-23 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of polymer type and drug dose on the in vitro and in vivo behavior of amorphous solid dispersions
Knopp, Matthias Manne, Chourak, N., Khan, F., Wendelboe, J., Langguth, P., Rades, Thomas & Holm, R., Aug 2016, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 105, p. 106-14 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Statistical Analysis of a Method to Predict Drug-Polymer Miscibility
Knopp, Matthias Manne, Olesen, N. E., Huang, Y., Holm, R. & Rades, Thomas, 5 Jan 2016, In: Journal of Pharmaceutical Sciences. 105, 1, p. 362–367 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of polymer molecular weight on in vitro dissolution behavior and in vivo performance of celecoxib:PVP amorphous solid dispersions
Knopp, Matthias Manne, Nguyen, J. H., Becker, C., Francke, N. M., Jørgensen, E. B., Holm, P., Holm, R., Mu, Huiling, Rades, Thomas & Langguth, P., Apr 2016, In: European Journal of Pharmaceutics and Biopharmaceutics. 101, p. 145-51 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evaluation of drug-polymer solubility curves through formal statistical analysis: comparison of preparation techniques
Knopp, Matthias Manne, Olesen, N. E., Holm, P., Löbmann, Korbinian, Holm, R., Langguth, P. & Rades, Thomas, Jan 2015, In: Journal of Pharmaceutical Sciences. 104, 1, p. 44-51 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Promising New Method to Estimate Drug-Polymer Solubility at Room Temperature
Knopp, Matthias Manne, Gannon, N., Porsch, I., Rask, M. B., Olesen, N. E., Langguth, P., Holm, R. & Rades, Thomas, Sep 2016, In: Journal of Pharmaceutical Sciences. 105, 9, p. 2621-2624 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparative Study of Different Methods for the Prediction of Drug-Polymer Solubility
Knopp, Matthias Manne, Tajber, L., Tian, Y., Olesen, N. E., Jones, D. S., Kozyra, A., Löbmann, Korbinian, Paluch, K., Brennan, C. M., Holm, R., Healy, A. M., Andrews, G. P. & Rades, Thomas, 8 Sep 2015, In: Molecular Pharmaceutics. 12, 9, p. 3408-19 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Investigating dehydration from compacts using terahertz pulsed, raman, and near-infrared spectroscopy
Kogermann, K., Zeitler, A. J., Rantanen, Jukka, Rades, Thomas, Taday, P. F., Pepper, M., Heinämäki, J. & Strachan, C. J., 2007, In: Applied Spectroscopy. 61, 12, p. 1265-1274Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Development and characterisation of modified poloxamer 407 thermoresponsive depot systems containing cubosomes
Kojarunchitt, T., Hook, S., Rizwan, S., Rades, Thomas & Baldursdottir, S., 2011, In: International Journal of Pharmaceutics. 408, 1-2, p. 20-26 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Modified thermoresponsive Poloxamer 407 and chitosan sol-gels as potential sustained-release vaccine delivery systems
Kojarunchitt, T., Baldursdottir, S., Dong, Y., Boyd, B. J., Rades, Thomas & Hook, S., Jan 2015, In: European Journal of Pharmaceutics and Biopharmaceutics. 89, p. 74-81 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Solventless amorphization and pelletization using a high shear granulator. Part I; feasibility study using indomethacin
Kondo, K. & Rades, Thomas, 2022, In: European Journal of Pharmaceutics and Biopharmaceutics. 181, p. 147-158Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Solventless amorphization and pelletization using a high shear granulator. Part II; Preparation of co-amorphous mixture-layered pellets using indomethacin and arginine
Kondo, K. & Rades, Thomas, 2022, In: European Journal of Pharmaceutics and Biopharmaceutics. 181, p. 183-194Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Using different structure types of microemulsions for the preparation of poly(alkylcyanoacrylate) nanoparticles by interfacial polymerization
Krauel, K., Davies, N. M., Hook, S. & Rades, Thomas, 18 Aug 2005, In: Journal of Controlled Release. 106, 1-2, p. 76-87 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterisation of colloidal drug delivery systems from the naked eye to Cryo-FESEM
Krauel, K., Girvan, L., Hook, S. & Rades, Thomas, 2007, In: Micron. 38, 8, p. 796-803 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Entrapment of bioactive molecules in poly (alkylcyanoacrylate) nanoparticles
Krauel, K., Pitaksuteepong, T., Davies, N. M. & Rades, Thomas, 2004, In: American Journal of Drug Delivery. 2, 4, p. 251-259 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Preparation of poly (alkylcyanoacrylate) nanoparticles by polymerization of water-free microemulsions
Krauel, K., Graf, A., Hook, S. M., Davies, N. M. & Rades, Thomas, 2006, In: Journal of Microencapsulation. 23, 5, p. 499-512 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of oral gavage technique of drug-containing microcontainers on the gastrointestinal transit and absorption in rats
Kristensen, M. N., Rades, Thomas, Boisen, A. & Mullertz, Anette , 2022, In: International Journal of Pharmaceutics. 618, 121630.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nanomechanical Infrared Spectroscopy with Vibrating Filters for Pharmaceutical Analysis
Kurek, M., Carnoy, M., Larsen, P. E., Nielsen, L. H., Hansen, O., Rades, Thomas, Schmid, S. & Boisen, A., 27 Mar 2017, In: Angewandte Chemie (International ed. in English). 56, 14, p. 3901-3905 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
A method for the incorporation of ovalbumin into immune stimulating complexes prepared by the hydration method
Könnings, S., Copland, M. J., Davies, N. M. & Rades, Thomas, 25 Jul 2002, In: International Journal of Pharmaceutics. 241, 2, p. 385-9 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Utilizing nanoparticles for improving anti-biofilm effects of azithromycin: A head-to-head comparison of modified hyaluronic acid nanogels and coated poly (lactic-co-glycolic acid) nanoparticles
Kłodzińska, S. N., Wan, F., Jumaa, H., Sternberg, C., Rades, Thomas & Nielsen, Hanne Mørck, 1 Nov 2019, In: Journal of Colloid and Interface Science. 555, p. 595-606 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hyaluronic acid-based nanogels improve in vivo compatibility of the anti-biofilm peptide DJK-5
Kłodzińska, S. N., Pletzer, D., Rahanjam, N., Rades, Thomas, Hancock, R. E. W. & Nielsen, Hanne Mørck, 2019, In: Nanomedicine: Nanotechnology, Biology, and Medicine. 20, 102022.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Spray-drying of inhalable, multifunctional formulations for the treatment of biofilms formed in cystic fibrosis
Lababidi, N., Kissi, E. O., Elgaher, W. A. M., Sigal, V., Haupenthal, J., Schwarz, B. C., Hirsch, A. K. H., Rades, Thomas & Schneider, M., 28 Nov 2019, In: Journal of Controlled Release. 314, p. 62-71Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Amino acids as co-amorphous excipients for simvastatin and glibenclamide: physical properties and stability
Laitinen, R., Löbmann, Korbinian, Grohganz, Holger, Strachan, C. & Rades, Thomas, 7 Jul 2014, In: Molecular Pharmaceutics. 11, 7, p. 2381-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Emerging trends in the stabilization of amorphous drugs
Laitinen, R., Löbmann, Korbinian, Strachan, C. J., Grohganz, Holger & Rades, Thomas, 30 Aug 2013, In: International Journal of Pharmaceutics. 453, 1, p. 65-79 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Supersaturating drug delivery systems: The potential of co-amorphous drug formulations
Laitinen, R., Löbmann, Korbinian, Grohganz, Holger, Priemel, P., Strachan, C. J. & Rades, Thomas, 30 Oct 2017, In: International Journal of Pharmaceutics. 532, 1, p. 1-12 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Theoretical Considerations in Developing Amorphous Solid Dispersions
Laitinen, R., Priemel, P. A., Surwase, S., Graeser, K., Strachan, C. J., Grohganz, Holger & Rades, Thomas, 2014, Amorphous Solid Dispersions - Theory and Practice. Shah, N., Sandhu, H., Choi, D. S., Chokshi, H. & Malick, A. W. (eds.). New York: Springer Science+Business Media, p. 35-90 56 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
A unifying approach to drug-in-polymer solubility prediction: Streamlining experimental workflow and analysis
Larsen, B. S., Meiland, Peter, Tzdaka, E., Tho, I. & Rades, Thomas, 2024, In: European Journal of Pharmaceutics and Biopharmaceutics. 203, 9 p., 114478.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nonlinear optics as a method for materials characterisation
Lee, C. J., Strachan, C. J., Rades, Thomas & Manson, P. J., 2007Research output: Book/Report › Book › Research › peer-review
Characterization of the bulk properties of pharmaceutical solids using nonlinear optics-a review
Lee, C. J., Strachan, C. J., Manson, P. J. & Rades, Thomas, 2007, In: Journal of Pharmacy and Pharmacology. 59, 2, p. 241-50 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cage-like complexes formed by DOTAP, Quil-A and cholesterol
Lendemans, D. G., Egert, A. M., Hook, S. & Rades, Thomas, 2007, In: International Journal of Pharmaceutics.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
On the dilution behaviour of immuno-stimulating complexes (ISCOMs)
Lendemans, D. G., Egert, A. M., Myschik, J., Hook, S. & Rades, Thomas, 2006, In: Pharmazie.Research output: Contribution to journal › Journal article › Research › peer-review
Immuno-stimulating complexes prepared by ethanol injection
Lendemans, D. G., Myschik, J., Hook, S. & Rades, Thomas, Jun 2005, In: Journal of Pharmacy and Pharmacology. 57, 6, p. 729-33 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
Cationic cage-like complexes formed by DC-cholesterol, Quil-A, and phospholipid
Lendemans, D. G., Myschik, J., Hook, S. & Rades, Thomas, 2005, In: Journal of Pharmaceutical Sciences. 94, 8, p. 1794-807 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Design of Inhalable Solid Dosage Forms of Budesonide and Theophylline for Pulmonary Combination Therapy
Leng, D., Kissi, E. O., Löbmann, Korbinian, Thanki, K., Fattal, E., Rades, Thomas, Foged, Camilla & Yang, Mingshi, 7 Mar 2019, In: AAPS PharmSciTech. 20, 3, 137.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Solid-state properties and dissolution behaviour of tablets containing co-amorphous indomethacin-arginine
Lenz, E., Jensen, K. B. T., Blaabjerg, L. I., Knop, K., Grohganz, Holger, Löbmann, Korbinian, Rades, Thomas & Kleinebudde, P., Oct 2015, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 96, p. 44–52 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hot Melt Extrusion and Spray Drying of Co-amorphous Indomethacin-Arginine With Polymers
Lenz, E., Löbmann, Korbinian, Rades, Thomas, Knop, K. & Kleinebudde, P., Jan 2017, In: Journal of Pharmaceutical Sciences. 106, 1, p. 302-312 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Emulsions as oral moisturisers for the treatment of severe xerostomia
Lewisham, K. M., Ferguson, M. M. & Rades, Thomas, 2001, In: Pharmazie.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Direct Comparison of Standard Transmission Electron Microscopy and Cryogenic-TEM in Imaging Nanocrystals Inside Liposomes
Li, T., Nowell, C. J., Cipolla, D., Rades, Thomas & Boyd, B. J., Apr 2019, In: Molecular Pharmaceutics. 16, 4, p. 1775-1781Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Controlling the size and shape of liposomal ciprofloxacin nanocrystals by varying the lipid bilayer composition and drug to lipid ratio
Li, T., Clulow, A. J., Nowell, C. J., Hawley, A., Cipolla, D., Rades, Thomas & Boyd, B. J., 2019, In: Journal of Colloid and Interface Science. 555, p. 361-372 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exposure of liposomes containing nanocrystallised ciprofloxacin to digestive media induces solid-state transformation and altered in vitro drug release
Li, T., Hawley, A., Rades, Thomas & Boyd, B. J., 2020, In: Journal of Controlled Release. 323, p. 350-360 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Solid State Characterization of Ciprofloxacin Liposome Nanocrystals
Li, T., Mudie, S., Cipolla, D., Rades, Thomas & Boyd, B. J., 2019, In: Molecular Pharmaceutics. 16, 1, p. 184-194 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Drug nanocrystallisation within liposomes
Li, T., Cipolla, D., Rades, Thomas & Boyd, B. J., 2018, In: Journal of Controlled Release. 288, p. 96-110 15 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
A new method for the determination of the unfrozen matrix concentration and the maximal freeze-concentration
Liesebach, J., Rades, Thomas & Lim, M., 19 May 2003, In: Thermochimica Acta. 401, 2, p. 159-168 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Determination of unfrozen matrix concentrations at low temperatures using stepwise DSC
Liesebach, J., Lim, M. & Rades, Thomas, 19 Feb 2004, In: Thermochimica Acta. 411, 1, p. 43-51 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Investigation of physical properties and stability of indomethacin-cimetidine and naproxen-cimetidine co-amorphous systems prepared by quench cooling, coprecipitation and ball milling
Lim, A. W., Löbmann, Korbinian, Grohganz, Holger, Rades, Thomas & Chieng, N., Jan 2016, In: Journal of Pharmacy and Pharmacology. 68, 1, p. 36-45 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Physical Changes in Confectionery Products Caused by the Availability of Water, with a Special Focus on Lactitol Crystallization
Lim, M. H., Lampen, B., Siow, L. F. & Rades, Thomas, 14 May 2010, Water Properties in Food, Health, Pharmaceutical and Biological Systems: ISOPOW 10. Wiley-Blackwell, p. 271-282 12 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Dose-related effects of lauric acid on antropyloroduodenal motility, gastrointestinal hormone release, appetite, and energy intake in healthy men
Little, T. J., Feltrin, K. L., Horowitz, M., Smout, A. J. P. M., Rades, Thomas, Meyer, J. H., Pilichiewicz, A. N., Wishart, J. & Feinle-Bisset, C., 2005, In: American Journal of Physiology - Regulatory Integrative and Comparative Physiology.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Functionalised calcium carbonate as a coformer to stabilize amorphous drugs by mechanochemical activation
Liu, J., Rades, Thomas, Tho, I. & Kissi, E. O., 2020, In: European Journal of Pharmaceutics and Biopharmaceutics. 155, p. 22-28 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of Molecular Surface Diffusion on the Physical Stability of Co-Amorphous Systems
Liu, J., Hwu, E., Bannow, J., Grohganz, Holger & Rades, Thomas, 2022, In: Molecular Pharmaceutics. 19, 4, p. 1183-1190Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of polymer addition on the amorphization, dissolution and physical stability of co-amorphous systems
Liu, J., Grohganz, Holger & Rades, Thomas, 2020, In: International Journal of Pharmaceutics. 588, p. 1-9 9 p., 119768.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Co-Amorphous Drug Formulations in Numbers: Recent Advances in Co-Amorphous Drug Formulations with Focus on Co-Formability, Molar Ratio, Preparation Methods, Physical Stability, In Vitro and In Vivo Performance, and New Formulation Strategies
Liu, J., Grohganz, Holger, Löbmann, Korbinian, Rades, Thomas & Hempel, N., 2021, In: Pharmaceutics. 13, 3, 43 p., 389.Research output: Contribution to journal › Review › Research
- Published
Determination of the Optimal Molar Ratio in Amino Acid-Based Coamorphous Systems
Liu, J., Rades, Thomas & Grohganz, Holger, 2020, In: Molecular Pharmaceutics. 17, 4, p. 1335-1342 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The influence of moisture on the storage stability of co-amorphous systems
Liu, J., Rades, Thomas & Grohganz, Holger, 2021, In: International Journal of Pharmaceutics. 605, 120802.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Simultaneous quantification of multiple RNA cargoes co-loaded into nanoparticle-based delivery systems
Lokras, Abhijeet, Chakravarty, A., Rades, Thomas, Christensen, D., Franzyk, Henrik, Thakur, A. & Foged, Camilla, 2022, In: International Journal of Pharmaceutics. 626, 13 p., 122171.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Amino acids as stabilizers for spray-dried simvastatin powder for inhalation
Lu, W., Rades, Thomas, Rantanen, Jukka, Chan, H. & Yang, Mingshi, 2020, In: International Journal of Pharmaceutics. 572, 12 p., 118724.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhalable co-amorphous budesonide-arginine dry powders prepared by spray drying
Lu, W., Rades, Thomas, Rantanen, Jukka & Yang, Mingshi, 30 Jun 2019, In: International Journal of Pharmaceutics. 565, p. 1-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Amino acids as co-amorphous stabilizers for poorly water-soluble drugs - Part 2: Molecular interactions
Löbmann, Korbinian, Laitinen, R., Strachan, C., Rades, Thomas & Grohganz, Holger, 1 Jan 2013, In: European Journal of Pharmaceutics and Biopharmaceutics. 85, 3, Part B, p. 882-888Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The influence of pressure on the intrinsic dissolution rate of amorphous indomethacin
Löbmann, Korbinian, Flouda, K., Qiu, D., Tsolakou, T., Wang, W. & Rades, Thomas, 2014, In: Pharmaceutics. 6, 3, p. 481-93 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Coamorphous drug systems: enhanced physical stability and dissolution rate of indomethacin and naproxen
Löbmann, Korbinian, Laitinen, R., Grohganz, Holger, Gordon, K. C., Strachan, C. & Rades, Thomas, 2011, In: Molecular Pharmaceutics. 8, 5, p. 1919-28 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A theoretical and spectroscopic study of co-amorphous naproxen and indomethacin
Löbmann, Korbinian, Laitinen, R., Grohganz, Holger, Strachan, C. J., Rades, Thomas & Gordon, K. C., 30 Aug 2013, In: International Journal of Pharmaceutics. 453, 1, p. 80-87 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Amino acids as co-amorphous stabilizers for poorly water soluble drugs--Part 1: preparation, stability and dissolution enhancement
Löbmann, Korbinian, Grohganz, Holger, Laitinen, R., Strachan, C. & Rades, Thomas, Nov 2013, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 85, 3 Pt B, p. 873-81 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Stabilized amorphous solid dispersions with small molecule excipients
Löbmann, Korbinian, Jensen, K. B. T., Laitinen, R., Rades, Thomas, Strachan, C. & Grohganz, Holger, 2014, Amorphous Solid Dispersions - Theory and Practice. Shah, N., Sandhu, H., Choi, D. S., Chokshi, H. & Malick, A. W. (eds.). New York: Springer Science+Business Media, p. 613-626 24 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Co-amorphous simvastatin and glipizide combinations show improved physical stability without evidence of intermolecular interactions
Löbmann, Korbinian, Strachan, C., Grohganz, Holger, Rades, Thomas, Korhonen, O. & Laitinen, R., 2012, In: European Journal of Pharmaceutics and Biopharmaceutics. 81, 1, p. 159-69 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Formulating Amorphous Drug Delivery System Using Low-Molecular-Weight Components as Stabilizers
Löbmann, Korbinian, Laitinen, R., Grohganz, Holger & Rades, Thomas, 2014, In: CRS Newsletter. 31, 3, p. 16-17Research output: Contribution to journal › Journal article › Communication
- Published
Ordnung muss (nicht) sein
Löbmann, Korbinian, Jensen, K. B. T., Grohganz, Holger & Rades, Thomas, 2012, In: Lægemiddelforskning. 2012, p. 34-36Research output: Contribution to journal › Journal article › Communication
- Published
Exploring the Impact of Intestinal Fluid Components on the Solubility and Supersaturation of Danazol
Madsen, C. M., Plum, J., Hens, B., Augustijns, P., Mullertz, Anette & Rades, Thomas, 2021, In: Journal of Pharmaceutical Sciences. 110, 6, p. 2479-2488 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Supersaturation of zafirlukast in fasted and fed state intestinal media with and without precipitation inhibitors
Madsen, C. M., Boyd, B., Rades, Thomas & Mullertz, Anette , 25 Aug 2016, In: European Journal of Pharmaceutical Sciences. 91, p. 31-39 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of composition of simulated intestinal media on the solubility of poorly soluble compounds investigated by design of experiments
Madsen, C. M., Feng, K., Leithead, A., Canfield, N., Jørgensen, S. A., Mullertz, Anette & Rades, Thomas, Jan 2018, In: European Journal of Pharmaceutical Sciences. 111, p. 311-319 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Simple measurements for prediction of drug release from polymer matrices - Solubility parameters and intrinsic viscosity
Madsen, C. G., Skov, A., Baldursdottir, S., Rades, Thomas, Jørgensen, Lene & Medlicott, N. J., 7 Feb 2015, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 92, p. 1-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen
Madsen, F. & Rades, Thomas, Jul 2013, In: Journal of Drug Delivery Science and Technology. 23, 4, p. 289-290 2 p.Research output: Contribution to journal › Editorial › Research › peer-review
- Published
The effect of surfactants on the dissolution behavior of amorphous formulations
Mah, P. T., Peltonen, L., Novakovic, D., Rades, Thomas, Strachan, C. J. & Laaksonen, T., Jun 2016, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 103, p. 13-22 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Differential scanning calorimetry predicts the critical quality attributes of amorphous glibenclamide
Mah, P. T., Laaksonen, T., Rades, Thomas, Peltonen, L. & Strachan, C. J., 1 Dec 2015, In: European Journal of Pharmaceutical Sciences. 80, p. 74-81 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Unravelling the relationship between degree of disorder and the dissolution behavior of milled glibenclamide
Mah, P. T., Laaksonen, T., Rades, Thomas, Aaltonen, J., Peltonen, L. & Strachan, C. J., 6 Jan 2014, In: Molecular Pharmaceutics. 11, 1, p. 234-242 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Use of low-frequency Raman spectroscopy and chemometrics for the quantification of crystallinity in amorphous griseofulvin tablets
Mah, P. T., Fraser, S. J., Reish, M. E., Rades, Thomas, Gordon, K. C. & Strachan, C. J., Mar 2015, In: Vibrational Spectroscopy. 77, p. 10-16 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Toward quality assessment of 3D printed oral dosage forms
Markl, D., Zeitler, A., Rades, Thomas, Rantanen, Jukka & Bøtker, Johan Peter, 15 Dec 2017, In: Journal of 3D Printing in Medicine. 2, 1, p. 27-33 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Analysis of 3D Prints by X-ray Computed Microtomography and Terahertz Pulsed Imaging
Markl, D., Zeitler, J. A., Rasch, C., Michaelsen, M. H., Mullertz, Anette , Rantanen, Jukka, Rades, Thomas & Bøtker, Johan Peter, 2017, In: Pharmaceutical Research. 34, 5, p. 1037–1052 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterisation of pore structures of pharmaceutical tablets: A review
Markl, D., Strobel, A., Schlossnikl, R., Bøtker, Johan Peter, Bawuah, P., Ridgway, C., Rantanen, Jukka, Rades, Thomas, Gane, P., Peiponen, K. & Zeitler, J. A., 5 Jan 2018, In: International Journal of Pharmaceutics. 538, 1, p. 188-214 27 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Zein-polycaprolactone core-shell nanofibers for wound healing
Martin, A., Cai, Jun, Gürtler, Anna-Lena, van der Plas, Mariena J.A., Malmsten, Martin, Rades, Thomas & Heinz, Andrea, 2022, In: International Journal of Pharmaceutics. 621, 10 p., 121809.Research output: Contribution to journal › Journal article › Research › peer-review
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In Situ Transformation of Electrospun Nanofibers into Nanofiber-Reinforced Hydrogels
Martin, A., Nyman, J. N., Reinholdt, R., Cai, Jun, Gürtler, Anna-Lena, van der Plas, Mariena J.A., Malmsten, Martin, Rades, Thomas & Heinz, Andrea, 2022, In: Nanomaterials. 12, 14, 2437.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Unveiling polyamorphism and polyamorphic interconversions in pharmaceuticals: the peculiar case of hydrochlorothiazide
Batista Martins, Inês Catarina, Larsen, A. S., Madsen, Anders Østergaard, Aalling-Frederiksen, Olivia, Correia, A., Jensen, Kirsten Marie Ørnsbjerg, Jeppesen, H. S. & Rades, Thomas, 2023, In: Chemical Science. 14, 41, p. 11447-11455 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
In vivo activity of cationic immune stimulating complexes (PLUSCOMs)
McBurney, W. T., Lendemans, D. G., Myschik, J., Hennessy, T., Rades, Thomas & Hook, S., 2008, In: Vaccine. 26, 35, p. 4549-56 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Application of pharmaceutical drug delivery for biological control of the common brushtail possum in New Zealand: A review
McDowell, A., McLeod, B. J., Rades, Thomas & Tucker, I. G., 2006, In: Wildlife Research.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Polymeric nanoparticles as an oral delivery system for biocontrol agents for the brushtail possum (trichosurus vulpecula)
McDowell, A., Rades, Thomas, Tucker, I. G. & McLeod, B. J., Dec 2009, In: New Zealand Veterinary Journal. 57, 6, p. 370-377 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of hydrogenated starch hydrolysates on the glass transition and crystallisation of sugar alcohols
McFetridge, J., Rades, Thomas & Lim, M., Jun 2004, In: Food Research International. 37, 5, p. 409-415 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quantification of binary polymorphic mixtures of ranitidine hydrochloride using NIR spectroscopy
McGoverin, C. M., Ho, L. C. H., Zeitler, J. A., Strachan, C. J., Gordon, K. C. & Rades, Thomas, 2006, In: Vibrational Spectroscopy.Research output: Contribution to journal › Journal article › Research › peer-review
Recent pharmaceutical applications of Raman and terahertz spectroscopies
McGoverin, C. M., Rades, Thomas & Gordon, K. C., 2008, In: Al Azhar Journal of Pharmaceutical Sciences. 97, 11, p. 4598-621 24 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A new method to determine drug-polymer solubility through enthalpy of melting and mixing
Meiland, Peter, Larsen, B. S., Knopp, Matthias Manne, Tho, I. & Rades, Thomas, 2022, In: International Journal of Pharmaceutics. 629, 9 p., 122391.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The use of molecular descriptors in the development of co-amorphous formulations
Meng-Lund, H. M. L., Korgaard, G. K., Jensen, K. B. T., Poso, A., Pantsar, T., Rades, Thomas, Rantanen, Jukka & Grohganz, Holger, 1 Jul 2018, In: European Journal of Pharmaceutical Sciences. 119, p. 31 38 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Functionalized calcium carbonate (FCC) as a novel carrier to solidify supersaturated self-nanoemulsifying drug delivery systems (super-SNEDDS)
Merchant, J., Mullertz, Anette , Rades, Thomas & Bannow, J., 2023, In: European Journal of Pharmaceutics and Biopharmaceutics. 193, p. 198-207Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Effect of Digestion and Drug Load on Halofantrine Absorption from Self-nanoemulsifying Drug Delivery System (SNEDDS)
Michaelsen, M. H., Wasan, K. M., Sivak, O., Mullertz, Anette & Rades, Thomas, Jan 2016, In: The A A P S Journal. 18, 1, p. 180-186 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fenofibrate oral absorption from SNEDDS and super-SNEDDS is not significantly affected by lipase inhibition in rats
Michaelsen, M. H., Siqueira Jørgensen, S. D., Abdi, I. M., Wasan, K. M., Rades, Thomas & Mullertz, Anette , 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 142, p. 258-264 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of preparation technique on co-amorphization of carvedilol with acidic amino acids
Mishra, J., Löbmann, Korbinian, Grohganz, Holger & Rades, Thomas, 1 Dec 2018, In: International Journal of Pharmaceutics. 552, 1-2, p. 407-413Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of Solvent Composition on the Performance of Spray-Dried Co-Amorphous Formulations
Mishra, J., Rades, Thomas, Löbmann, Korbinian & Grohganz, Holger, 12 Apr 2018, In: Pharmaceutics. 10, 2, p. 1-13Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A co-amorphous form of a substance and a protein
Mishra, J., Bohr, A., Berg, T. H. A., Löbmann, Korbinian, Rades, Thomas, Grohganz, Holger & Water, J. J., 2019, Patent No. US201903078886A1Research output: Patent
- Published
Whey proteins as stabilizers in amorphous solid dispersions
Mishra, J., Bohr, A., Rades, Thomas, Grohganz, Holger & Löbmann, Korbinian, 1 Feb 2019, In: European Journal of Pharmaceutical Sciences. 128, p. 144-151 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Solvent free amorphisation for pediatric formulations (minitablets) using mesoporous silica
Monsuur, F., Choudhari, Y., Reddy, U., McCarthy, W., Sadek, I., Grohganz, Holger, Rades, Thomas & Löbmann, Korbinian, 25 Sep 2016, In: International Journal of Pharmaceutics. 511, 2, p. 1135-1136Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
High-Throughput Lipolysis in 96-Well Plates for Rapid Screening of Lipid-Based Drug Delivery Systems
Mosgaard, M. D., Sassene, P. J., Mu, Huiling, Rades, Thomas & Mullertz, Anette , Apr 2017, In: Journal of Pharmaceutical Sciences. 106, 4, p. 1183-1186 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Development of a high-throughput in vitro intestinal lipolysis model for rapid screening of lipid-based drug delivery systems
Mosgaard, M. D., Sassene, P., Mu, Huiling, Rades, Thomas & Mullertz, Anette , Aug 2015, In: European Journal of Pharmaceutics and Biopharmaceutics. 94, p. 493-500 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Crystal morphology modification by the addition of tailor-made stereocontrolled poly(N-isopropyl acrylamide)
Munk, T., Baldursdottir, S., Hietala, S., Rades, Thomas, Kapp, S., Nuopponen, M., Kalliomäki, K., Tenhu, H. & Rantanen, Jukka, 2012, In: Molecular Pharmaceutics. 9, 7, p. 1932-1941Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Investigation of the phase separation of PNIPAM using infrared spectroscopy together with multivariate data analysis
Munk, T., Baldursdottir, S. G., Hietala, S., Rades, Thomas, Nuopponen, M., Kalliomäki, K., Tenhu, H., Rantanen, Jukka & Strachan, C. S., 2013, In: Polymer. 54, 26, p. 6947-6953 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Immunogenicity of lipid sustained release implants containing imiquimod, α-galactosylceramide, or Quil-A
Myschik, J., McBurney, W. T., Hennessy, T., Rades, Thomas & Hook, S., Sep 2008, In: Pharmazie. 63, 9, p. 686-692 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Advances in lipid-based subunit vaccine formulations
Myschik, J., Rades, Thomas & Hook, S., 2009, In: Current Immunology Reviews.Research output: Contribution to journal › Journal article › Research › peer-review
Immunostimulatory biodegradable implants containing the adjuvant Quil-A--Part I: Physicochemical characterisation
Myschik, J., Eberhardt, F., Rades, Thomas & Hook, S., 2008, In: Journal of Drug Targeting. 16, 3, p. 213-23 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
On the preparation, microscopic investigation and application of ISCOMs
Myschik, J., Lendemans, D. G., McBurney, W. T., Demana, P. H., Hook, S. & Rades, Thomas, 2006, In: Micron. 37, 8, p. 724-34 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Immunostimulatory biodegradable implants containing the adjuvant Quil-A--Part II: In vivo evaluation
Myschik, J., McBurney, W. T., Hennessy, T., Phipps-Green, A., Rades, Thomas & Hook, S., 2008, In: Journal of Drug Targeting. 16, 3, p. 224-32 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Immunostimulatory lipid implants containing Quil-A and DC-cholesterol
Myschik, J., McBurney, W. T., Rades, Thomas & Hook, S., 2008, In: International Journal of Pharmaceutics. 363, 1-2, p. 91-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
New perspectives on lipid and surfactant based drug delivery systems for oral delivery of poorly soluble drugs
Mullertz, Anette , Ogbonna, A., Ren, S. & Rades, Thomas, 2010, In: Journal of Pharmacy and Pharmacology. 62, 11, p. 1622-1636 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Polymorphic form of piroxicam influences the performance of armorphous material prepared by ball-milling
Naelapaa, K., Bøtker, Johan Peter, Veski, P., Rantanen, Jukka, Rades, Thomas & Kogermann, K., 2012, In: International Journal of Pharmaceutics. 429, 1-2, p. 69-77Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Indomethacin-omeprazole as therapeutic hybrids? Salt and co-amorphous systems enhancing physicochemical and pharmacological properties
Carneiro Soares Do Nascimento, A L, Batista Martins, Inês Catarina, Spósito, L., Morais-Silva, G., Duarte, J. L., Rades, Thomas & Chorilli, M., 2024, In: International Journal of Pharmaceutics. 653, 11 p., 123857.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Activation of the NLRP3 inflammasome is not a feature of all particulate vaccine adjuvants
Neumann, S., Burkert, K., Kemp, R., Rades, Thomas, Rod Dunbar, P. & Hook, S., 1 Apr 2014, In: Immunology and Cell Biology. 92, p. 535-542Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Preparation of an amorphous sodium furosemide salt improves solubility and dissolution rate and leads to a faster Tmax after oral dosing to rats
Nielsen, L. H., Gordon, S., Holm, R., Selen, A., Rades, Thomas & Mullertz, Anette , Nov 2013, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 85, 3 Pt B, p. 942-51 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization during storage and dissolution of Solid dispersions containing furosemide and hydroxypropyl methylcellulose
Nielsen, L. H., Rades, Thomas & Mullertz, Anette , 1 Jul 2013, In: Journal of Drug Delivery Science and Technology. 23, 4, p. 409-415 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Spatial confinement can lead to increased stability of amorphous indomethacin
Nielsen, L. H., Keller, S. S., Gordon, K. C., Boisen, A., Rades, Thomas & Mullertz, Anette , 2012, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 81, 2, p. 418-25 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Stabilisation of amorphous furosemide increases the oral drug bioavailability in rats
Nielsen, L. H., Rades, Thomas & Mullertz, Anette , 25 Jul 2015, In: International Journal of Pharmaceutics. 490, 1-2, p. 334-40 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A slow cooling rate of indomethacin melt spatially confined in microcontainers increases the physical stability of the amorphous drug without influencing its biorelevant dissolution behaviour
Nielsen, L. H., Keller, S. S., Boisen, A., Mullertz, Anette & Rades, Thomas, Jun 2014, In: Drug Delivery and Translational Research. 4, 3, p. 268-74 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Microcontainers as an oral delivery system for spray dried cubosomes containing ovalbumin
Nielsen, L. H., Rades, Thomas, Boyd, B. J. & Boisen, A., Sep 2017, In: European Journal of Pharmaceutics and Biopharmaceutics. 118, p. 13-20Research output: Contribution to journal › Journal article › Research › peer-review
- Published
pH-triggered drug release from biodegradable microwells for oral drug delivery
Nielsen, L. H., Nagstrup, J., Gordon, S., Keller, S. S., Østergaard, Jesper, Rades, Thomas, Mullertz, Anette & Boisen, A., Jun 2015, In: Biomedical Microdevices. 17, 7 p., 55.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Biorelevant characterisation of amorphous furosemide salt exhibits conversion to a furosemide hydrate during dissolution
Nielsen, L. H., Gordon, S., Pajander, J. P., Østergaard, Jesper, Rades, Thomas & Mullertz, Anette , 30 Nov 2013, In: International Journal of Pharmaceutics. 457, 1, p. 14-24 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Polymeric microcontainers improve oral bioavailability of furosemide
Nielsen, L. H., Melero, A., Keller, S. S., Jacobsen, Jette, Garrigues, T., Rades, Thomas, Mullertz, Anette & Boisen, A., 17 May 2016, In: International Journal of Pharmaceutics. 504, 1-2, p. 98-109 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Combining lipid based drug delivery and amorphous solid dispersions for improved oral drug absorption of a poorly water-soluble drug
Nora, G., Venkatasubramanian, R., Strindberg, S., Siqueira-Jørgensen, S. D., Pagano, L., Romanski, F. S., Swarnakar, N. K., Rades, Thomas & Mullertz, Anette , 2022, In: Journal of Controlled Release. 349, p. 206-212Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Multispectral UV Imaging for Determination of the Tablet Coating Thickness
Novikova, A., Carstensen, J. M., Zeitler, J. A., Rades, Thomas & Leopold, C. S., Jun 2017, In: Journal of Pharmaceutical Sciences. 106, 6, p. 1560-1569 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Multispectral UV imaging for surface analysis of MUPS tablets with special focus on the pellet distribution
Novikova, A., Carstensen, J. M., Rades, Thomas & Leopold, P. D. C. S., 1 Oct 2016, In: International Journal of Pharmaceutics. 515, 1-2, p. 374-383 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A non-destructive method for quality control of the pellet distribution within a MUPS tablet by terahertz pulsed imaging
Novikova, A., Markl, D., Axel Zeitler, J., Rades, Thomas & Leopold, C. S., Jan 2018, In: European Journal of Pharmaceutical Sciences. 111, p. 549-555Research output: Contribution to journal › Journal article › Research › peer-review
- Published
UV imaging of multiple unit pellet system (MUPS) tablets: A case study of acetylsalicylic acid stability
Novikova, A., Carstensen, J. M., Rades, Thomas & Leopold, C. S., Oct 2017, In: European Journal of Pharmaceutics and Biopharmaceutics. 119, p. 447-453 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of Polyvinylpyrrolidone Molecular Weight and Concentration on the Precipitation Inhibition of Supersaturated Solutions of Poorly Soluble Drugs
Odeh, A. B., El-Sayed, B., Knopp, Matthias Manne, Rades, Thomas & Blaabjerg, L. I., 2023, In: Pharmaceutics. 15, 6, 17 p., 1601.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparison of the liquisolid technique and co-milling for loading of a poorly soluble drug in inorganic porous excipients
Ogadah, C. U., Mrštná, K., Matysová, L., Mullertz, Anette , Rades, Thomas, Niederquell, A., Šklubalová, Z. & Vraníková, B., 2024, In: International Journal of Pharmaceutics. 650, 10 p., 123702.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Single particles as resonators for thermomechanical analysis
Okeyo, P. O., Larsen, P. E., Kissi, E. O., Ajalloueian, F., Rades, Thomas, Rantanen, Jukka & Boisen, A., 2020, In: Nature Communications. 11, 1, 11 p., 1235.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Imaging of dehydration in particulate matter using Raman line-focus microscopy
Okeyo, P. O., Ilchenko, O., Slipets, R., Larsen, P. E., Boisen, A., Rades, Thomas & Rantanen, Jukka, 17 May 2019, In: Scientific Reports. 9, 11 p., 7525.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Development of Self-Nanoemulsifying Drug Delivery Systems Containing 4-Allylpyrocatechol for Treatment of Oral Infections Caused by Candida albicans
Okonogi, S., Phumat, P., Khongkhunthian, S., Chaijareenont, P., Rades, Thomas & Mullertz, Anette , 2021, In: Pharmaceutics. 13, 2, 16 p., 167.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Enhancing Stability and Tooth Bleaching Activity of Carbamide Peroxide by Electrospun Nanofibrous Film
Okonogi, S., Kaewpinta, A., Rades, Thomas, Mullertz, Anette , Yang, Mingshi, Khongkhunthian, S. & Chaijareenont, P., 2020, In: Pharmaceuticals. 13, 11, 20 p., 381.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lipid nanoparticles for local delivery of mRNA to the respiratory tract: Effect of PEG-lipid content and administration route
Ongun, Melike, Lokras, Abhijeet, Baghel, Saahil Sandeep, Shi, Zhenning, Schmidt, S. T., Franzyk, Henrik, Rades, Thomas, Sebastiani, Federica, Thakur, A. & Foged, Camilla, 2024, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 198, 10 p., 114266.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Application of an online post-column derivatization HPLC-DPPH assay to detect compounds responsible for antioxidant activity in Sonchus oleraceus L. leaf extracts
Ou, Z., Schmierer, D. M., Rades, Thomas, Larsen, L. & McDowell, A., 2013, In: Journal of Pharmacy and Pharmacology. 65, 2, p. 271-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Anti-Ageing Effects of Sonchus oleraceus L. (pūhā) Leaf Extracts on H2O2-Induced Cell Senescence
Ou, Z., Rades, Thomas & McDowell, A., 2015, In: Molecules. 20, 3, p. 4548-64 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of postharvest processing and storage conditions on key antioxidants in pūhā (Sonchus oleraceus L.)
Ou, Z., Schmierer, D. M., Strachan, C. J., Rades, Thomas & McDowell, A., 12 Feb 2014, In: The Journal of pharmacy and pharmacology. 66, 7, p. 998-1008 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Role of polymeric excipients in the stabilization of olanzapine when exposed to aqueous environments
Paisana, M., Wahl, M., Pinto, J., Rades, Thomas (ed.), Grohganz, Holger (ed.) & Löbmann, Korbinian (ed.), 2015, In: Molecules. 20, 12, p. 22634-223282 200649.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Studying the propensity of compounds to supersaturate: a practical and broadly applicable approach
Palmelund, H., Madsen, C. M., Christensen, J. P., Mullertz, Anette & Rades, Thomas, Oct 2016, In: Journal of Pharmaceutical Sciences. 105, 10, p. 3021-3029 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exploring the fate of liposomes in the intestine by dynamic in vitro lipolysis
Parmentier, J., Thomas, N., Mullertz, Anette , Fricker, G. & Rades, Thomas, 2012, In: International Journal of Pharmaceutics. 437, 1-2, p. 253-63 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Drug quality in South Africa: perceptions of key players involved in medicines distribution
Patel, A., Norris, P., Gauld, R. & Rades, Thomas, 2009, In: International Journal of Health Care Quality Assurance. 22, 5, p. 547-60 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quality of generic medicines in South Africa: perceptions versus reality - a qualitative study
Patel, A., Gauld, R., Norris, P. & Rades, Thomas, 2012, In: B M C Health Services Research. 12, p. 297Research output: Contribution to journal › Journal article › Research › peer-review
"This body does not want free medicines": South African consumer perceptions of drug quality
Patel, A., Gauld, R., Norris, P. & Rades, Thomas, 2010, In: Health Policy and Planning. 25, 1, p. 61-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Physical stability and solubility of the thermotropic mesophase of fenoprofen calcium as pure drug and in a tablet formulation
Patterson, J., Bary, A. & Rades, Thomas, 24 Oct 2002, In: International Journal of Pharmaceutics. 247, 1-2, p. 147-57 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Melt extrusion and spray drying of carbamazepine and dipyridamole with polyvinylpyrrolidone/vinyl acetate copolymers
Patterson, J. E., James, M. B., Forster, A. H. & Rades, Thomas, 2008, In: Drug Development and Industrial Pharmacy. 34, 1, p. 95-106 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
The influence of thermal and mechanical preparative techniques on the amorphous state of four poorly soluble compounds
Patterson, J. E., James, M. B., Forster, A. H., Lancaster, R. W., Butler, J. M. & Rades, Thomas, 2005, In: Journal of Pharmaceutical Sciences. 94, 9, p. 1998-2012 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
Preparation of glass solutions of three poorly water soluble drugs by spray drying, melt extrusion and ball milling
Patterson, J. E., James, M. B., Forster, A. H., Lancaster, R. W., Butler, J. M. & Rades, Thomas, 2007, In: International Journal of Pharmaceutics. 336, 1, p. 22-34 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Enhancing tabletability of high-dose tablets by tailoring properties of spray-dried insulin particles
Pedersen, M. D., Megarry, A., Naelapää, K., Rades, Thomas & Pessi, J., 2023, In: International Journal of Pharmaceutics. 631, 8 p., 122526.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Physico-chemical characterization of aspirated and simulated human gastric fluids to study their influence on the intrinsic dissolution rate of cinnarizine
Pedersen, P. B., Berthelsen, R., Rades, Thomas, Jørgensen, S. A., Vilmann, Peter, Bar-Shalom, Daniel, Baldursdottir, S. & Mullertz, Anette , 2022, In: International Journal of Pharmaceutics. 622, 7 p., 121856.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Principles of controlled release
Perrie, Y., Rades, Thomas & Graeser, K., 15 Sep 2016, Drug Delivery: Fundamentals and Applications: Second Edition. CRC Press, p. 25-46 22 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
Themed issue: improve dissolution, solubility and bioavailability of poorly soluble drugs
Perrie, Y. & Rades, Thomas, 2010, In: Journal of Pharmacy and Pharmacology. 62, 11, p. 1517-8 2 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
Advanced characterisation techniques
Perrie, Y. & Rades, Thomas, 2011, In: International Journal of Pharmaceutics. 417, 1-2, p. 1-2 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Solid state properties and drug release behavior of co-amorphous indomethacin-arginine tablets coated with Kollicoat® Protect
Petry, I., Löbmann, Korbinian, Grohganz, Holger, Rades, Thomas & Leopold, C. S., Oct 2017, In: European Journal of Pharmaceutics and Biopharmaceutics. 119, p. 150-160 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Undesired co-amorphisation of indomethacin and arginine during combined storage at high humidity conditions
Petry, I., Löbmann, Korbinian, Grohganz, Holger, Rades, Thomas & Leopold, C. S., 2018, In: International Journal of Pharmaceutics. 544, 1, p. 172-180 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In situ co-amorphisation in coated tablets – The combination of carvedilol with aspartic acid during immersion in an acidic medium
Petry, I., Löbmann, Korbinian, Grohganz, Holger, Rades, Thomas & Leopold, C. S., 10 Mar 2019, In: International Journal of Pharmaceutics. 558, p. 357-366 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In situ co-amorphisation of arginine with indomethacin or furosemide during immersion in an acidic medium – A proof of concept study
Petry, I., Löbmann, Korbinian, Grohganz, Holger, Rades, Thomas & Leopold, C. S., 1 Dec 2018, In: European Journal of Pharmaceutics and Biopharmaceutics. 133, p. 151-160 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quantification of the types of water in Eudragit RLPO polymer and the kinetics of water loss using FTIR
Pirayavaraporn, C., Rades, Thomas, Gordon, K. C. & Tucker, I. G., 15 Dec 2013, In: International Journal of Pharmaceutics. 458, 1, p. 90-98 9 p.Research output: Contribution to journal › Journal article › Research
- Published
Determination of moisture content in relation to thermal behaviour and plasticization of Eudragit RLPO
Pirayavaraporn, C., Rades, Thomas & Tucker, I. G., 17 Jan 2012, In: International Journal of Pharmaceutics. 422, 1-2, p. 68-74 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Uptake of antigen encapsulated in polyethylcyanoacrylate nanoparticles by D1-dendritic cells
Pitaksuteepong, T., Davies, N. M., Baird, M. & Rades, Thomas, Feb 2004, In: Pharmazie. 59, 2, p. 134-142 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Factors influencing the entrapment of hydrophilic compounds in nanocapsules prepared by interfacial polymerisation of water-in-oil microemulsions
Pitaksuteepong, T., Davies, N. M., Tucker, I. G. & Rades, Thomas, May 2002, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 53, 3, p. 335-42 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparison of induction methods for supersaturation: Amorphous dissolution versus solvent shift
Plum, J., Bavnhoj, C. G., Eliasen, Jannik Nicklas, Rades, Thomas & Mullertz, Anette , 2020, In: European Journal of Pharmaceutics and Biopharmaceutics. 152, p. 35-43 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Investigation of the Intra- and Interlaboratory Reproducibility of a Small Scale Standardized Supersaturation and Precipitation Method
Plum, J., Madsen, C. M., Teleki, A., Bevernage, J., da Costa Mathews, C., Karlsson, E. M., Carlert, S., Holm, R., Müller, T., Matthews, W., Sayers, A., Ojala, K., Tsinsman, K., Lingamaneni, R., Bergström, C. A., Rades, Thomas & Mullertz, Anette , 7 Nov 2017, In: Molecular Pharmaceutics. 14, 12, p. 4161-4169Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparison of induction methods for supersaturation: pH shift versus solvent shift
Plum, J., Bavnhoj, C., Palmelund, H., Perez-Alos, L., Mullertz, Anette & Rades, Thomas, 5 Jan 2020, In: International Journal of Pharmaceutics. 573, 8 p., 118862.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of chitosan-magnesium aluminum silicate nanocomposite films for buccal delivery of nicotine
Pongjanyakul, T., Khunawattanakul, W., Strachan, C. J., Gordon, K. C., Puttipipatkhachorn, S. & Rades, Thomas, 2013, In: International Journal of Biological Macromolecules. 55, p. 24-31 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quantitative analysis of polymorphic mixtures of ranitidine hydrochloride by raman spectroscopy and principal components analysis
Pratiwi, D., Paul Fawcett, J., Gordon, K. C. & Rades, Thomas, Nov 2002, In: European Journal of Pharmaceutics and Biopharmaceutics. 54, 3, p. 337-341 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Unintended and in situ amorphisation of pharmaceuticals
Priemel, P. A., Grohganz, Holger & Rades, Thomas, 1 May 2016, In: Advanced Drug Delivery Reviews. 100, p. 126-32 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhibition of surface crystallisation of amorphous indomethacin particles in physical drug-polymer mixtures
Priemel, P. A., Laitinen, R., Barthold, S., Grohganz, Holger, Lehto, V., Rades, Thomas & Strachan, C. J., 18 Nov 2013, In: International Journal of Pharmaceutics. 456, 2, p. 301-6 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In situ amorphisation of indomethacin with Eudragit® E during dissolution
Priemel, P. A., Laitinen, R., Grohganz, Holger, Rades, Thomas & Strachan, C. J., Nov 2013, In: European Journal of Pharmaceutics and Biopharmaceutics. 85, 3 Pt B, p. 1259-65 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The impact of surface- and nano-crystallisation on the detected amorphous content and the dissolution behaviour of amorphous indomethacin
Priemel, P. A., Grohganz, Holger, Gordon, K. C., Rades, Thomas & Strachan, C., 2012, In: European Journal of Pharmaceutics and Biopharmaceutics. 82, 1, p. 187-193Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Electron and light microscopical investigation of defect structures in mesophases of pharmaceutical substances
Rades, Thomas & Müller-Goymann, C. C., 1997, In: Colloid and Polymer Science.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Melting behaviour and thermotropic mesomorphism of fenoprofen salts
Rades, Thomas & Muller-Goymann, C. C., 1994, In: European Journal of Pharmaceutics and Biopharmaceutics.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Interactions between gelatin and amphiphilic substances
Rades, Thomas, Schutze, W. & Muller-Goymann, C. C., 1993, In: Pharmazie.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of amphiphilic substances on the coil-helix transformation of gelatin
Rades, Thomas, Schutze, W., Hirsch, R. & Muller-Goymann, C. C., 1994, In: Pharmazie.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Thermal behaviour and solubility of fenoprofen calcium
Rades, Thomas, Padmadisastra, Y. & Müller-Goymann, C. C., 1996, In: Pharmazie.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of a commercial liposome spray
Rades, Thomas, Gerke, A., Schütze, W. & Müller-Goymann, C. C., 1997, In: Pharmazie.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Investigations on the micellisation behaviour of fenoprofen sodium
Rades, Thomas & Müller-Goymann, C. C., 1997, In: International Journal of Pharmaceutics.Research output: Contribution to journal › Journal article › Research › peer-review
Pharmaceutics: drug delivery and targeting
Rades, Thomas & Perrie, Y., 2012, 2. ed. London: Pharmaceutical Press. 239 p. (FASTtrack).Research output: Book/Report › Book › Research › peer-review
- Published
Investigating to Optimal Ratio between Drug and Co-Former in Co-Amorphous Systems
Rades, Thomas, 2021, In: Proceedings. 78, 1, 1 p., 27.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Solid-state analysis for pharmaceuticals: Pathways to feasible and meaningful analysis
Rantanen, Jukka, Rades, Thomas & Strachan, C., 2023, In: Journal of Pharmaceutical and Biomedical Analysis. 236, 7 p., 115649.Research output: Contribution to journal › Review › Research › peer-review
- Published
Influence of PVP/VA copolymer composition on drug-polymer solubility
Rask, M. B., Knopp, Matthias Manne, Olesen, N. E., Holm, R. & Rades, Thomas, 31 Mar 2016, In: European Journal of Pharmaceutical Sciences. 85, p. 10-17 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparison of two DSC-based methods to predict drug-polymer solubility
Rask, M. B., Knopp, Matthias Manne, Olesen, N. E., Holm, R. & Rades, Thomas, 5 Apr 2018, In: International Journal of Pharmaceutics. 540, 1-2, p. 98-105Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transcutaneous immunization using microneedles and cubosomes: Mechanistic investigations using Optical Coherence Tomography and Two-Photon Microscopy
Rattanapak, T., Birchall, J., Young, K., Ishii, M., Meglinski, I., Rades, Thomas & Hook, S., 28 Dec 2013, In: Journal of controlled release : official journal of the Controlled Release Society. 172, 3, p. 894-903 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparative study of liposomes, transfersomes, ethosomes and cubosomes for transcutaneous immunisation: characterisation and in vitro skin penetration
Rattanapak, T., Young, K., Rades, Thomas & Hook, S., 2012, In: Journal of Pharmacy and Pharmacology. 64, 11, p. 1560-9 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Towards characterization and identification of solid state pharmaceutical mixtures through second harmonic generation
Rawle, C. B., Lee, C. J., Strachan, C. J., Payne, K., Manson, P. J. & Rades, Thomas, 2006, In: Journal of Pharmaceutical Sciences. 95, 4, p. 761-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A case study of real-time monitoring of solid-state phase transformations in acoustically levitated particles using near infrared and Raman spectroscopy
Rehder, S., Wu, J., Laackmann, J., Moritz, H., Rantanen, Jukka, Rades, Thomas & Leopold, C. S., 2013, In: European Journal of Pharmaceutical Sciences. 48, 1-2, p. 97-103 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High-shear granulation as a manufacturing method for cocrystal granules
Rehder, S., Christensen, N. P. A., Rantanen, Jukka, Rades, Thomas & Leopold, C. S., Nov 2013, In: European Journal of Pharmaceutics and Biopharmaceutics. 85, 3, Part B, p. 1019-30 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Investigation of the formation process of two piracetam cocrystals during grinding
Rehder, S., Klukkert, M., Löbmann, Korbinian, Strachan, C. J., Sakmann, A., Gordon, K., Rades, Thomas & Leopold, C. S., 2011, In: Pharmaceutics. 3, 4, p. 706-722 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Thermal degradation of amorphous glibenclamide
Rehder, S., Sakmann, A., Rades, Thomas & Leopold, C. S., Jan 2012, In: European Journal of Pharmaceutics and Biopharmaceutics. 80, 1, p. 203-208 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exploring the Solid-State Landscape of Carbamazepine during Dehydration: A Low Frequency Raman Spectroscopy Perspective
Remoto, P. I. I. I. J. G., Bērziņš, Kārlis, Fraser-Miller, S. J., Korter, T. M., Rades, Thomas, Rantanen, Jukka & Gordon, K. C., 2023, In: Pharmaceutics. 15, 5, 15 p., 1526.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Elucidating the Dehydration Mechanism of Nitrofurantoin Monohydrate II Using Low-Frequency Raman Spectroscopy
Remoto, P. J. G., Bērziņš, Kārlis, Fraser-Miller, S. J., Korter, T. M., Rades, Thomas, Rantanen, Jukka & Gordon, K. C., 2022, In: Crystal Growth and Design. 22, 4, p. 2733-2741Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Preparation of phytantriol cubosomes by solvent precursor dilution for the delivery of protein vaccines
Rizwan, S. B., Assmus, D., Boehnke, A., Hanley, T., Boyd, Ben, Rades, Thomas & Hook, S., Sep 2011, In: European Journal of Pharmaceutics and Biopharmaceutics. 79, 1, p. 15-22 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Liquid crystalline systems of phytantriol and glyceryl monooleate containing a hydrophilic protein: Characterisation, swelling and release kinetics
Rizwan, S. B., Hanley, T., Boyd, Ben, Rades, Thomas & Hook, S., Nov 2009, In: Journal of Pharmaceutical Sciences. 98, 11, p. 4191-4204 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterisation of bicontinuous cubic liquid crystalline systems of phytantriol and water using cryo field emission scanning electron microscopy (cryo FESEM)
Rizwan, S. B., Dong, Y., Boyd, Ben, Rades, Thomas & Hook, S., 2007, In: Micron.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cubosomes contaning the adjuvants imiquimod and monophosphryl lipid A stimulate robust cellular and humoral immune respones
Rizwan, S. B., McBurney, W. T., Young, K., Boyd, B. J., Rades, Thomas & Hook, B., 2013, In: Journal of Controlled Release. 165, 1, p. 16-21Research output: Contribution to journal › Journal article › Research › peer-review
Bicontinuous cubic liquid crystals as sustained delivery systems for peptides and proteins
Rizwan, S. B., Boyd, B. J., Rades, Thomas & Hook, S., 2010, In: Expert Opinion on Drug Delivery. 7, 10, p. 1133-44 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Monitoring the Isothermal Dehydration of Crystalline Hydrates Using Low-Frequency Raman Spectroscopy
Robert, C., Fraser-Miller, S. J., Bērziņš, Kārlis, Okeyo, P. O., Rantanen, Jukka, Rades, Thomas & Gordon, K. C., 2021, In: Molecular Pharmaceutics. 18, 3, p. 1264-1276Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Immune responses induced by nano-self-assembled lipid adjuvants based on a monomycoloyl glycerol analogue after vaccination with the Chlamydia trachomatis major outer membrane protein
Rodrigues, L., Raftopoulos, K. N., Tandrup Schmidt, S., Schneider, F., Dietz, H., Rades, Thomas, Franzyk, Henrik, Pedersen, Anders Elm, Papadakis, C. M., Christensen, D., Winter, G., Foged, Camilla & Hubert, M., 10 Sep 2018, In: Journal of controlled release : official journal of the Controlled Release Society. 285, p. 12-22 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The significance of the amorphous potential energy landscape for dictating glassy dynamics and driving solid-state crystallisation
Ruggiero, M. T., Krynski, M., Kissi, E. O., Sibik, J., Markl, D., Tan, N. Y., Arslanov, D., van der Zande, W., Redlich, B., Korter, T. M., Grohganz, Holger, Löbmann, Korbinian, Rades, Thomas, Elliott, S. R. & Zeitler, J. A., 2017, In: Physical chemistry chemical physics : PCCP. 19, 44, p. 30039-30047Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Microcontainers for oral insulin delivery - in vitro studies of permeation enhancement
Rune Jørgensen, J., Leth Jepsen, M., Hagner Nielsen, L., Dufva, M., Nielsen, Hanne Mørck, Rades, Thomas, Boisen, A. & Mullertz, Anette , 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 143, p. 98-105Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Applications of Raman spectroscopy in aqueous environments
Sandler, N., Savolainen, M., Saupe, A., Strachan, C. & Rades, Thomas, 2007, In: Pharmaceutical Technology Europe.Research output: Contribution to journal › Journal article › Research
- Published
Comparison of lipases for in vitro models of gastric digestion: lipolysis using two infant formulas as model substrates
Sassene, P. J., Fanø, M., Mu, Huiling, Rades, Thomas, Aquistapace, S., Schmitt, B., Cruz-Hernandez, C., Wooster, T. J. & Mullertz, Anette , 14 Sep 2016, In: Food & Function. 7, 9, p. 3989-3998 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In Vivo Precipitation of Poorly Soluble Drugs from Lipid-Based Drug Delivery Systems
Sassene, P. J., Michaelsen, M. H., Mosgaard, M. D., Klitgaard, Mette, Van Den Broek, E., Wasan, K. M., Mu, Huiling, Rades, Thomas & Mullertz, Anette , 3 Oct 2016, In: Molecular Pharmaceutics. 13, 10, p. 3417-3426 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Precipitation of a poorly soluble model drug during in vitro lilpolysis: characterization and dissolution of the precipitate
Sassene, P. J., Knopp, Matthias Manne, Hesselkilde, J. Z., Koradia, V., Larsen, A., Rades, Thomas & Mullertz, Anette , 2010, In: Journal of Pharmaceutical Sciences. 99, 12, p. 4982-4991Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Elucidating the molecular interactions occurring during drug precipitation of weak bases from lipid-based formulations: a case study with cinnarizine and a long chain self-nanoemulsifying drug delivery system
Sassene, P. J., Mosgaard, M. D., Löbmann, Korbinian, Mu, Huiling, Larsen, F. H., Rades, Thomas & Mullertz, Anette , 2015, In: Molecular Pharmaceutics. 12, 11, p. 4067-4076 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Solid lipid nanoparticles
Saupe, A. & Rades, Thomas, 2006Research output: Book/Report › Book › Research › peer-review
Immunostimulatory colloidal delivery systems for cancer vaccines
Saupe, A., McBurney, W., Rades, Thomas & Hook, S., 2006, In: Expert Opinion on Drug Delivery. 3, 3, p. 345-54 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Structural investigations on nanoemulsions, solid lipid nanoparticles and nanostructured lipid carriers by cryo-field emission scanning electron microscopy and Raman spectroscopy
Saupe, A., Gordon, K. C. & Rades, Thomas, 2006, In: International Journal of Pharmaceutics. 314, 1, p. 56-62 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
Screening for differences in the amorphous state of indomethacin using multivariate visualization
Savolainen, M., Heinz, Andrea, Strachan, C., Gordon, K. C., Yliruusi, J., Rades, Thomas & Sandler, N., 2007, In: European Journal of Pharmaceutical Sciences. 30, 2, p. 113-123Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Spectroscopic Evidence of Tertiary Structural Differences Between Insulin Molecules in Fibrils
Schack, M. M., Dahl, K., Rades, Thomas, Groenning, M. & Carpenter, J. F., 2019, In: Journal of Pharmaceutical Sciences. 108, 9, p. 2871-2879Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Optimization of Infrared Microscopy to Assess Secondary Structure of Insulin Molecules Within Individual Subvisible Particles in Aqueous Formulations
Schack, M. M., Moller, E. H., Friderichsen, A. V., Carpenter, J. F., Rades, Thomas & Groenning, M., 2019, In: Journal of Pharmaceutical Sciences. 108, 3, p. 1117-1129Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Platform for Preparing Homogeneous Proteinaceous Subvisible Particles With Distinct Morphologies
Schack, M. M., Moller, E. H., Carpenter, J. F., Rades, Thomas & Groenning, M., Jul 2018, In: Journal of Pharmaceutical Sciences. 107, 7, p. 1842-1851Research output: Contribution to journal › Journal article › Research › peer-review
- Published
in vivo evaluation of chitosan as an adjuvant in subcutaneous vaccine formulations
Scherließ, R., Buske, S., Young, K., Weber, B., Rades, Thomas & Hook, S., 1 Oct 2013, In: Vaccine. 31, 42, p. 4812-9 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Systematic investigation of the role of surfactant composition and choice of oil: Design of a nanoemulsion-based adjuvant inducing concomitant humoral and CD4+ T-cell responses
Schmidt, S. T., Neustrup, M. A., Rønholt, Stine, Korsholm, K. S., Rades, Thomas, Andersen, P., Christensen, D. & Foged, Camilla, Aug 2017, In: Pharmaceutical Research. 34, 8, p. 1716-1727 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Induction of Cytotoxic T-Lymphocyte Responses Upon Subcutaneous Administration of a Subunit Vaccine Adjuvanted With an Emulsion Containing the Toll-Like Receptor 3 Ligand Poly(I:C)
Schmidt, S. T., Pedersen, G. K., Neustrup, M. A., Korsholm, K. S., Rades, Thomas, Andersen, P., Foged, Camilla & Christensen, D., 30 Apr 2018, In: Frontiers in Immunology. 9, 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The administration route is decisive for the ability of the vaccine adjuvant CAF09 to induce antigen-specific CD8(+) T-cell responses: The immunological consequences of the biodistribution profile
Schmidt, S. T., Khadke, S., Korsholm, K. S., Perrie, Y., Rades, Thomas, Andersen, P., Foged, Camilla & Christensen, D., 26 Aug 2016, In: Journal of controlled release : official journal of the Controlled Release Society. 239, p. 107-117 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Liposome-Based Adjuvants for Subunit Vaccines: Formulation Strategies for Subunit Antigens and Immunostimulators
Schmidt, S. T., Foged, Camilla, Korsholm, K. S., Rades, Thomas & Christensen, D., 10 Mar 2016, In: Pharmaceutics. 8, 1, 22 p., 7.Research output: Contribution to journal › Review › Research › peer-review
Studies on the lipase-induced degradation of lipid-based drug delivery systems. Part II - Investigations on the mechanisms leading to collapse of the lipid structure
Schwab, M., McGoverin, C. M., Gordon, K. C., Winter, G., Rades, Thomas, Myschik, J. & Strachan, C. J., Aug 2013, In: European Journal of Pharmaceutics and Biopharmaceutics. 84, 3, p. 456-63 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Simultaneous automated image analysis and Raman spectroscopy of powders at an individual particle level
Sekulovic, A., Verrijk, R., Rades, Thomas, Grabarek, A., Jiskoot, W., Hawe, A. & Rantanen, Jukka, 2021, In: Journal of Pharmaceutical and Biomedical Analysis. 193, 8 p., 113744.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Probabilistic modeling of an injectable aqueous crystalline suspension using influence networks
Sekulovic, A., Petit, M., Verrijk, R., Rades, Thomas & Rantanen, Jukka, 2021, In: International Journal of Pharmaceutics. 596, 11 p., 120283.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Development of a Microgram Scale Video-Microscopic Method to Investigate Dissolution Behavior of Poorly Water-Soluble Drugs
Senniksen, M. B., Christfort, J. F., Marabini, R., Spillum, E., Matthews, W., Da Vià, L., Plum, J., Rades, Thomas & Mullertz, Anette , 2022, In: AAPS PharmSciTech. 23, 6, 173.Research output: Contribution to journal › Journal article › Research › peer-review
Solvent change co-precipitation with hydroxypropyl methylcellulose phthalate to improve dissolution characteristics of a poorly water-soluble drug
Sertsou, G., Butler, J., Hempenstall, J. & Rades, Thomas, Aug 2002, In: Journal of Pharmacy and Pharmacology. 54, 8, p. 1041-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
Factors affecting incorporation of drug into solid solution with HPMCP during solvent change co-precipitation
Sertsou, G., Butler, J., Scott, A., Hempenstall, J. & Rades, Thomas, 1 Oct 2002, In: International Journal of Pharmaceutics. 245, 1-2, p. 99-108 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Physical stability and enthalpy relaxation of drug-hydroxypropyl methylcellulose phthalate solvent change co-precipitates
Sertsou, G., Butler, J., Hempenstall, J. & Rades, Thomas, 1 Jan 2003, In: Journal of Pharmacy and Pharmacology. 55, 1, p. 35-41 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Predicting Crystallization of Amorphous Drugs with Terahertz Spectroscopy
Sibik, J., Löbmann, Korbinian, Rades, Thomas & Zeitler, J. A., 3 Aug 2015, In: Molecular Pharmaceutics. 12, 8, p. 3062-68 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Poorly soluble drugs
Siepmann, J., Rades, Thomas, Mullertz, Anette & Loftsson, T., 15 Mar 2020, In: International Journal of Pharmaceutics. 577, 119055.Research output: Contribution to journal › Editorial › Research
- Published