Thomas Rades
Professor
Solid State Pharmaceutics
Universitetsparken 2, 2100 København Ø
Pharmaceuticals, processes and products
Universitetsparken 2
2100 København Ø
Introductory remarks on publicationslist
Publication Statistics
(data until September 2020)
Books 3 Book chapters 17 Int. peer reviewed journal articles 450
Professional journal articles 32
Conference contributions >700
Patents 13
H Index (Google Scholar) 76
Total number of citations (Google Scholar) 20346
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Investigation of physical properties and stability of indomethacin-cimetidine and naproxen-cimetidine co-amorphous systems prepared by quench cooling, coprecipitation and ball milling
Lim, A. W., Löbmann, Korbinian, Grohganz, Holger, Rades, Thomas & Chieng, N., Jan 2016, In: Journal of Pharmacy and Pharmacology. 68, 1, p. 36-45 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Physical Changes in Confectionery Products Caused by the Availability of Water, with a Special Focus on Lactitol Crystallization
Lim, M. H., Lampen, B., Siow, L. F. & Rades, Thomas, 14 May 2010, Water Properties in Food, Health, Pharmaceutical and Biological Systems: ISOPOW 10. Wiley-Blackwell, p. 271-282 12 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Dose-related effects of lauric acid on antropyloroduodenal motility, gastrointestinal hormone release, appetite, and energy intake in healthy men
Little, T. J., Feltrin, K. L., Horowitz, M., Smout, A. J. P. M., Rades, Thomas, Meyer, J. H., Pilichiewicz, A. N., Wishart, J. & Feinle-Bisset, C., 2005, In: American Journal of Physiology - Regulatory Integrative and Comparative Physiology.Research output: Contribution to journal › Journal article › Research › peer-review
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Functionalised calcium carbonate as a coformer to stabilize amorphous drugs by mechanochemical activation
Liu, J., Rades, Thomas, Tho, I. & Kissi, E. O., 2020, In: European Journal of Pharmaceutics and Biopharmaceutics. 155, p. 22-28 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Impact of Molecular Surface Diffusion on the Physical Stability of Co-Amorphous Systems
Liu, J., Hwu, E., Bannow, J., Grohganz, Holger & Rades, Thomas, 2022, In: Molecular Pharmaceutics. 19, 4, p. 1183-1190Research output: Contribution to journal › Journal article › Research › peer-review
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Influence of polymer addition on the amorphization, dissolution and physical stability of co-amorphous systems
Liu, J., Grohganz, Holger & Rades, Thomas, 2020, In: International Journal of Pharmaceutics. 588, p. 1-9 9 p., 119768.Research output: Contribution to journal › Journal article › Research › peer-review
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Co-Amorphous Drug Formulations in Numbers: Recent Advances in Co-Amorphous Drug Formulations with Focus on Co-Formability, Molar Ratio, Preparation Methods, Physical Stability, In Vitro and In Vivo Performance, and New Formulation Strategies
Liu, J., Grohganz, Holger, Löbmann, Korbinian, Rades, Thomas & Hempel, N., 2021, In: Pharmaceutics. 13, 3, 43 p., 389.Research output: Contribution to journal › Review › Research
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Determination of the Optimal Molar Ratio in Amino Acid-Based Coamorphous Systems
Liu, J., Rades, Thomas & Grohganz, Holger, 2020, In: Molecular Pharmaceutics. 17, 4, p. 1335-1342 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The influence of moisture on the storage stability of co-amorphous systems
Liu, J., Rades, Thomas & Grohganz, Holger, 2021, In: International Journal of Pharmaceutics. 605, 120802.Research output: Contribution to journal › Journal article › Research › peer-review
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Simultaneous quantification of multiple RNA cargoes co-loaded into nanoparticle-based delivery systems
Lokras, Abhijeet, Chakravarty, A., Rades, Thomas, Christensen, D., Franzyk, Henrik, Thakur, A. & Foged, Camilla, 2022, In: International Journal of Pharmaceutics. 626, 13 p., 122171.Research output: Contribution to journal › Journal article › Research › peer-review
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Amino acids as stabilizers for spray-dried simvastatin powder for inhalation
Lu, W., Rades, Thomas, Rantanen, Jukka, Chan, H. & Yang, Mingshi, 2020, In: International Journal of Pharmaceutics. 572, 12 p., 118724.Research output: Contribution to journal › Journal article › Research › peer-review
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Inhalable co-amorphous budesonide-arginine dry powders prepared by spray drying
Lu, W., Rades, Thomas, Rantanen, Jukka & Yang, Mingshi, 30 Jun 2019, In: International Journal of Pharmaceutics. 565, p. 1-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Amino acids as co-amorphous stabilizers for poorly water-soluble drugs - Part 2: Molecular interactions
Löbmann, Korbinian, Laitinen, R., Strachan, C., Rades, Thomas & Grohganz, Holger, 1 Jan 2013, In: European Journal of Pharmaceutics and Biopharmaceutics. 85, 3, Part B, p. 882-888Research output: Contribution to journal › Journal article › Research › peer-review
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The influence of pressure on the intrinsic dissolution rate of amorphous indomethacin
Löbmann, Korbinian, Flouda, K., Qiu, D., Tsolakou, T., Wang, W. & Rades, Thomas, 2014, In: Pharmaceutics. 6, 3, p. 481-93 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Coamorphous drug systems: enhanced physical stability and dissolution rate of indomethacin and naproxen
Löbmann, Korbinian, Laitinen, R., Grohganz, Holger, Gordon, K. C., Strachan, C. & Rades, Thomas, 2011, In: Molecular Pharmaceutics. 8, 5, p. 1919-28 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A theoretical and spectroscopic study of co-amorphous naproxen and indomethacin
Löbmann, Korbinian, Laitinen, R., Grohganz, Holger, Strachan, C. J., Rades, Thomas & Gordon, K. C., 30 Aug 2013, In: International Journal of Pharmaceutics. 453, 1, p. 80-87 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Amino acids as co-amorphous stabilizers for poorly water soluble drugs--Part 1: preparation, stability and dissolution enhancement
Löbmann, Korbinian, Grohganz, Holger, Laitinen, R., Strachan, C. & Rades, Thomas, Nov 2013, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 85, 3 Pt B, p. 873-81 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Stabilized amorphous solid dispersions with small molecule excipients
Löbmann, Korbinian, Jensen, K. B. T., Laitinen, R., Rades, Thomas, Strachan, C. & Grohganz, Holger, 2014, Amorphous Solid Dispersions - Theory and Practice. Shah, N., Sandhu, H., Choi, D. S., Chokshi, H. & Malick, A. W. (eds.). New York: Springer Science+Business Media, p. 613-626 24 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Co-amorphous simvastatin and glipizide combinations show improved physical stability without evidence of intermolecular interactions
Löbmann, Korbinian, Strachan, C., Grohganz, Holger, Rades, Thomas, Korhonen, O. & Laitinen, R., 2012, In: European Journal of Pharmaceutics and Biopharmaceutics. 81, 1, p. 159-69 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Formulating Amorphous Drug Delivery System Using Low-Molecular-Weight Components as Stabilizers
Löbmann, Korbinian, Laitinen, R., Grohganz, Holger & Rades, Thomas, 2014, In: CRS Newsletter. 31, 3, p. 16-17Research output: Contribution to journal › Journal article › Communication
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Ordnung muss (nicht) sein
Löbmann, Korbinian, Jensen, K. B. T., Grohganz, Holger & Rades, Thomas, 2012, In: Lægemiddelforskning. 2012, p. 34-36Research output: Contribution to journal › Journal article › Communication
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Exploring the Impact of Intestinal Fluid Components on the Solubility and Supersaturation of Danazol
Madsen, C. M., Plum, J., Hens, B., Augustijns, P., Mullertz, Anette & Rades, Thomas, 2021, In: Journal of Pharmaceutical Sciences. 110, 6, p. 2479-2488 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Supersaturation of zafirlukast in fasted and fed state intestinal media with and without precipitation inhibitors
Madsen, C. M., Boyd, B., Rades, Thomas & Mullertz, Anette , 25 Aug 2016, In: European Journal of Pharmaceutical Sciences. 91, p. 31-39 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effect of composition of simulated intestinal media on the solubility of poorly soluble compounds investigated by design of experiments
Madsen, C. M., Feng, K., Leithead, A., Canfield, N., Jørgensen, S. A., Mullertz, Anette & Rades, Thomas, Jan 2018, In: European Journal of Pharmaceutical Sciences. 111, p. 311-319 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Simple measurements for prediction of drug release from polymer matrices - Solubility parameters and intrinsic viscosity
Madsen, C. G., Skov, A., Baldursdottir, S., Rades, Thomas, Jørgensen, Lene & Medlicott, N. J., 7 Feb 2015, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 92, p. 1-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The effect of surfactants on the dissolution behavior of amorphous formulations
Mah, P. T., Peltonen, L., Novakovic, D., Rades, Thomas, Strachan, C. J. & Laaksonen, T., Jun 2016, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 103, p. 13-22 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Differential scanning calorimetry predicts the critical quality attributes of amorphous glibenclamide
Mah, P. T., Laaksonen, T., Rades, Thomas, Peltonen, L. & Strachan, C. J., 1 Dec 2015, In: European Journal of Pharmaceutical Sciences. 80, p. 74-81 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Unravelling the relationship between degree of disorder and the dissolution behavior of milled glibenclamide
Mah, P. T., Laaksonen, T., Rades, Thomas, Aaltonen, J., Peltonen, L. & Strachan, C. J., 6 Jan 2014, In: Molecular Pharmaceutics. 11, 1, p. 234-242 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Use of low-frequency Raman spectroscopy and chemometrics for the quantification of crystallinity in amorphous griseofulvin tablets
Mah, P. T., Fraser, S. J., Reish, M. E., Rades, Thomas, Gordon, K. C. & Strachan, C. J., Mar 2015, In: Vibrational Spectroscopy. 77, p. 10-16 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Toward quality assessment of 3D printed oral dosage forms
Markl, D., Zeitler, A., Rades, Thomas, Rantanen, Jukka & Bøtker, Johan Peter, 15 Dec 2017, In: Journal of 3D Printing in Medicine. 2, 1, p. 27-33 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Analysis of 3D Prints by X-ray Computed Microtomography and Terahertz Pulsed Imaging
Markl, D., Zeitler, J. A., Rasch, C., Michaelsen, M. H., Mullertz, Anette , Rantanen, Jukka, Rades, Thomas & Bøtker, Johan Peter, 2017, In: Pharmaceutical Research. 34, 5, p. 1037–1052 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Characterisation of pore structures of pharmaceutical tablets: A review
Markl, D., Strobel, A., Schlossnikl, R., Bøtker, Johan Peter, Bawuah, P., Ridgway, C., Rantanen, Jukka, Rades, Thomas, Gane, P., Peiponen, K. & Zeitler, J. A., 5 Jan 2018, In: International Journal of Pharmaceutics. 538, 1, p. 188-214 27 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Zein-polycaprolactone core-shell nanofibers for wound healing
Martin, A., Cai, J., Gürtler, Anna-Lena, van der Plas, Mariena J.A., Malmsten, Martin, Rades, Thomas & Heinz, Andrea, 2022, In: International Journal of Pharmaceutics. 621, 10 p., 121809.Research output: Contribution to journal › Journal article › Research › peer-review
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In Situ Transformation of Electrospun Nanofibers into Nanofiber-Reinforced Hydrogels
Martin, A., Nyman, J. N., Reinholdt, R., Cai, J., Gürtler, Anna-Lena, van der Plas, Mariena J.A., Malmsten, Martin, Rades, Thomas & Heinz, Andrea, 2022, In: Nanomaterials. 12, 14, 2437.Research output: Contribution to journal › Journal article › Research › peer-review
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Unveiling polyamorphism and polyamorphic interconversions in pharmaceuticals: the peculiar case of hydrochlorothiazide
Batista Martins, Inês Catarina, Larsen, A. S., Madsen, Anders Østergaard, Aalling-Frederiksen, Olivia, Correia, A., Jensen, Kirsten Marie Ørnsbjerg, Jeppesen, H. S. & Rades, Thomas, 2023, In: Chemical Science. 14, 41, p. 11447-11455 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
In vivo activity of cationic immune stimulating complexes (PLUSCOMs)
McBurney, W. T., Lendemans, D. G., Myschik, J., Hennessy, T., Rades, Thomas & Hook, S., 2008, In: Vaccine. 26, 35, p. 4549-56 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Application of pharmaceutical drug delivery for biological control of the common brushtail possum in New Zealand: A review
McDowell, A., McLeod, B. J., Rades, Thomas & Tucker, I. G., 2006, In: Wildlife Research.Research output: Contribution to journal › Journal article › Research › peer-review
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Polymeric nanoparticles as an oral delivery system for biocontrol agents for the brushtail possum (trichosurus vulpecula)
McDowell, A., Rades, Thomas, Tucker, I. G. & McLeod, B. J., Dec 2009, In: New Zealand Veterinary Journal. 57, 6, p. 370-377 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Influence of hydrogenated starch hydrolysates on the glass transition and crystallisation of sugar alcohols
McFetridge, J., Rades, Thomas & Lim, M., Jun 2004, In: Food Research International. 37, 5, p. 409-415 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Quantification of binary polymorphic mixtures of ranitidine hydrochloride using NIR spectroscopy
McGoverin, C. M., Ho, L. C. H., Zeitler, J. A., Strachan, C. J., Gordon, K. C. & Rades, Thomas, 2006, In: Vibrational Spectroscopy.Research output: Contribution to journal › Journal article › Research › peer-review
Recent pharmaceutical applications of Raman and terahertz spectroscopies
McGoverin, C. M., Rades, Thomas & Gordon, K. C., 2008, In: Al Azhar Journal of Pharmaceutical Sciences. 97, 11, p. 4598-621 24 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A new method to determine drug-polymer solubility through enthalpy of melting and mixing
Meiland, Peter, Larsen, B. S., Knopp, Matthias Manne, Tho, I. & Rades, Thomas, 2022, In: International Journal of Pharmaceutics. 629, 9 p., 122391.Research output: Contribution to journal › Journal article › Research › peer-review
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The use of molecular descriptors in the development of co-amorphous formulations
Meng-Lund, H. M. L., Korgaard, G. K., Jensen, K. B. T., Poso, A., Pantsar, T., Rades, Thomas, Rantanen, Jukka & Grohganz, Holger, 1 Jul 2018, In: European Journal of Pharmaceutical Sciences. 119, p. 31 38 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Functionalized calcium carbonate (FCC) as a novel carrier to solidify supersaturated self-nanoemulsifying drug delivery systems (super-SNEDDS)
Merchant, J., Mullertz, Anette , Rades, Thomas & Bannow, J., 2023, In: European Journal of Pharmaceutics and Biopharmaceutics. 193, p. 198-207Research output: Contribution to journal › Journal article › Research › peer-review
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The Effect of Digestion and Drug Load on Halofantrine Absorption from Self-nanoemulsifying Drug Delivery System (SNEDDS)
Michaelsen, M. H., Wasan, K. M., Sivak, O., Mullertz, Anette & Rades, Thomas, Jan 2016, In: The A A P S Journal. 18, 1, p. 180-186 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Fenofibrate oral absorption from SNEDDS and super-SNEDDS is not significantly affected by lipase inhibition in rats
Michaelsen, M. H., Siqueira Jørgensen, S. D., Abdi, I. M., Wasan, K. M., Rades, Thomas & Mullertz, Anette , 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 142, p. 258-264 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Influence of preparation technique on co-amorphization of carvedilol with acidic amino acids
Mishra, J., Löbmann, Korbinian, Grohganz, Holger & Rades, Thomas, 1 Dec 2018, In: International Journal of Pharmaceutics. 552, 1-2, p. 407-413Research output: Contribution to journal › Journal article › Research › peer-review
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Influence of Solvent Composition on the Performance of Spray-Dried Co-Amorphous Formulations
Mishra, J., Rades, Thomas, Löbmann, Korbinian & Grohganz, Holger, 12 Apr 2018, In: Pharmaceutics. 10, 2, p. 1-13Research output: Contribution to journal › Journal article › Research › peer-review
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A co-amorphous form of a substance and a protein
Mishra, J., Bohr, A., Berg, T. H. A., Löbmann, Korbinian, Rades, Thomas, Grohganz, Holger & Water, J. J., 2019, Patent No. US201903078886A1Research output: Patent
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Whey proteins as stabilizers in amorphous solid dispersions
Mishra, J., Bohr, A., Rades, Thomas, Grohganz, Holger & Löbmann, Korbinian, 1 Feb 2019, In: European Journal of Pharmaceutical Sciences. 128, p. 144-151 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 38132533
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491
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Analysis of 3D Prints by X-ray Computed Microtomography and Terahertz Pulsed Imaging
Research output: Contribution to journal › Journal article › Research › peer-review
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337
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The significance of the amorphous potential energy landscape for dictating glassy dynamics and driving solid-state crystallisation
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
303
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Comparison of lipases for in vitro models of gastric digestion: lipolysis using two infant formulas as model substrates
Research output: Contribution to journal › Journal article › Research › peer-review
Published