Thomas Rades

Thomas Rades

Professor

ORCID: 0000-0002-7521-6020

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  1. Published

    From Water to Ice: Investigation of the Effect of Ice Crystal Reduction on the Stability of Frozen Large Unilamellar Vesicles

    Siow, L. F., Rades, Thomas & Lim, M. H., 14 May 2010, Water Properties in Food, Health, Pharmaceutical and Biological Systems: ISOPOW 10. Wiley-Blackwell, p. 551-562 12 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  2. Effect of intra- and extra-liposomal distribution of sodium chloride on the stability of large unilamellar vesicles

    Siow, L. F., Rades, Thomas & Lim, M. H., 2012, In: Cryo-Letters. 28, 6, p. 429-44 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Cryo-responses of two types of large unilamellar vesicles in the presence of non-permeable or permeable cryoprotecting agents

    Siow, L. F., Rades, Thomas & Lim, M. H., 2008, In: Cryobiology. 57, 3, p. 276-85 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Characterizing the freezing behavior of liposomes as a tool to understand the cryopreservation procedures

    Siow, L. F., Rades, Thomas & Lim, M. H., 2007, In: Cryobiology. 55, 3, p. 210-21 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Dry hybrid lipid-silica microcapsules engineered from submicron lipid droplets and nanoparticles as a novel delivery system for poorly soluble drugs

    Simovic, S., Heard, P., Hui, H., Song, Y., Peddie, F., Davey, A. K., Lewis, A., Rades, Thomas & Prestidge, C. A., 2012, In: Molecular Pharmaceutics. 6, 3, p. 861-72 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    An oral delivery system for indomethicin engineered from cationic lipid emulsions and silica nanoparticles

    Simovic, S., Hui, H., Song, Y., Davey, A. K., Rades, Thomas & Prestidge, C. A., 2010, In: Journal of controlled release : official journal of the Controlled Release Society. 143, 3, p. 367-73 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Poorly soluble drugs

    Siepmann, J., Rades, Thomas, Mullertz, Anette & Loftsson, T., 15 Mar 2020, In: International Journal of Pharmaceutics. 577, 119055.

    Research output: Contribution to journal › Editorial › Research

  8. Published

    Pharmaceutical Technology in Europe

    Siepmann, J., Basit, A. & Rades, Thomas, 2022, In: International Journal of Pharmaceutics. 613, 1 p., 121441.

    Research output: Contribution to journal › Editorial › Research

  9. Published

    Predicting Crystallization of Amorphous Drugs with Terahertz Spectroscopy

    Sibik, J., Löbmann, Korbinian, Rades, Thomas & Zeitler, J. A., 3 Aug 2015, In: Molecular Pharmaceutics. 12, 8, p. 3062-68 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Solvent change co-precipitation with hydroxypropyl methylcellulose phthalate to improve dissolution characteristics of a poorly water-soluble drug

    Sertsou, G., Butler, J., Hempenstall, J. & Rades, Thomas, Aug 2002, In: Journal of Pharmacy and Pharmacology. 54, 8, p. 1041-7 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Factors affecting incorporation of drug into solid solution with HPMCP during solvent change co-precipitation

    Sertsou, G., Butler, J., Scott, A., Hempenstall, J. & Rades, Thomas, 1 Oct 2002, In: International Journal of Pharmaceutics. 245, 1-2, p. 99-108 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Physical stability and enthalpy relaxation of drug-hydroxypropyl methylcellulose phthalate solvent change co-precipitates

    Sertsou, G., Butler, J., Hempenstall, J. & Rades, Thomas, 1 Jan 2003, In: Journal of Pharmacy and Pharmacology. 55, 1, p. 35-41 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Development of a Microgram Scale Video-Microscopic Method to Investigate Dissolution Behavior of Poorly Water-Soluble Drugs

    Senniksen, M. B., Christfort, J. F., Marabini, R., Spillum, E., Matthews, W., Da Vià, L., Plum, J., Rades, Thomas & Mullertz, Anette , 2022, In: AAPS PharmSciTech. 23, 6, 173.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Simultaneous automated image analysis and Raman spectroscopy of powders at an individual particle level

    Sekulovic, A., Verrijk, R., Rades, Thomas, Grabarek, A., Jiskoot, W., Hawe, A. & Rantanen, Jukka, 2021, In: Journal of Pharmaceutical and Biomedical Analysis. 193, 8 p., 113744.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Probabilistic modeling of an injectable aqueous crystalline suspension using influence networks

    Sekulovic, A., Petit, M., Verrijk, R., Rades, Thomas & Rantanen, Jukka, 2021, In: International Journal of Pharmaceutics. 596, 11 p., 120283.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Studies on the lipase-induced degradation of lipid-based drug delivery systems. Part II - Investigations on the mechanisms leading to collapse of the lipid structure

    Schwab, M., McGoverin, C. M., Gordon, K. C., Winter, G., Rades, Thomas, Myschik, J. & Strachan, C. J., Aug 2013, In: European Journal of Pharmaceutics and Biopharmaceutics. 84, 3, p. 456-63 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Systematic investigation of the role of surfactant composition and choice of oil: Design of a nanoemulsion-based adjuvant inducing concomitant humoral and CD4+ T-cell responses

    Schmidt, S. T., Neustrup, M. A., Rønholt, Stine, Korsholm, K. S., Rades, Thomas, Andersen, P., Christensen, D. & Foged, Camilla, Aug 2017, In: Pharmaceutical Research. 34, 8, p. 1716-1727 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Induction of Cytotoxic T-Lymphocyte Responses Upon Subcutaneous Administration of a Subunit Vaccine Adjuvanted With an Emulsion Containing the Toll-Like Receptor 3 Ligand Poly(I:C)

    Schmidt, S. T., Pedersen, G. K., Neustrup, M. A., Korsholm, K. S., Rades, Thomas, Andersen, P., Foged, Camilla & Christensen, D., 30 Apr 2018, In: Frontiers in Immunology. 9, 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    The administration route is decisive for the ability of the vaccine adjuvant CAF09 to induce antigen-specific CD8(+) T-cell responses: The immunological consequences of the biodistribution profile

    Schmidt, S. T., Khadke, S., Korsholm, K. S., Perrie, Y., Rades, Thomas, Andersen, P., Foged, Camilla & Christensen, D., 26 Aug 2016, In: Journal of controlled release : official journal of the Controlled Release Society. 239, p. 107-117 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Liposome-Based Adjuvants for Subunit Vaccines: Formulation Strategies for Subunit Antigens and Immunostimulators

    Schmidt, S. T., Foged, Camilla, Korsholm, K. S., Rades, Thomas & Christensen, D., 10 Mar 2016, In: Pharmaceutics. 8, 1, 22 p., 7.

    Research output: Contribution to journal › Review › Research › peer-review

  21. Published

    in vivo evaluation of chitosan as an adjuvant in subcutaneous vaccine formulations

    Scherließ, R., Buske, S., Young, K., Weber, B., Rades, Thomas & Hook, S., 1 Oct 2013, In: Vaccine. 31, 42, p. 4812-9 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Spectroscopic Evidence of Tertiary Structural Differences Between Insulin Molecules in Fibrils

    Schack, M. M., Dahl, K., Rades, Thomas, Groenning, M. & Carpenter, J. F., 2019, In: Journal of Pharmaceutical Sciences. 108, 9, p. 2871-2879

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Optimization of Infrared Microscopy to Assess Secondary Structure of Insulin Molecules Within Individual Subvisible Particles in Aqueous Formulations

    Schack, M. M., Moller, E. H., Friderichsen, A. V., Carpenter, J. F., Rades, Thomas & Groenning, M., 2019, In: Journal of Pharmaceutical Sciences. 108, 3, p. 1117-1129

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    A Platform for Preparing Homogeneous Proteinaceous Subvisible Particles With Distinct Morphologies

    Schack, M. M., Moller, E. H., Carpenter, J. F., Rades, Thomas & Groenning, M., Jul 2018, In: Journal of Pharmaceutical Sciences. 107, 7, p. 1842-1851

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Screening for differences in the amorphous state of indomethacin using multivariate visualization

    Savolainen, M., Heinz, Andrea, Strachan, C., Gordon, K. C., Yliruusi, J., Rades, Thomas & Sandler, N., 2007, In: European Journal of Pharmaceutical Sciences. 30, 2, p. 113-123

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Immunostimulatory colloidal delivery systems for cancer vaccines

    Saupe, A., McBurney, W., Rades, Thomas & Hook, S., 2006, In: Expert Opinion on Drug Delivery. 3, 3, p. 345-54 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Structural investigations on nanoemulsions, solid lipid nanoparticles and nanostructured lipid carriers by cryo-field emission scanning electron microscopy and Raman spectroscopy

    Saupe, A., Gordon, K. C. & Rades, Thomas, 2006, In: International Journal of Pharmaceutics. 314, 1, p. 56-62 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Solid lipid nanoparticles

    Saupe, A. & Rades, Thomas, 2006

    Research output: Book/Report › Book › Research › peer-review

  29. Published

    Elucidating the molecular interactions occurring during drug precipitation of weak bases from lipid-based formulations: a case study with cinnarizine and a long chain self-nanoemulsifying drug delivery system

    Sassene, P. J., Mosgaard, M. D., Löbmann, Korbinian, Mu, Huiling, Larsen, F. H., Rades, Thomas & Mullertz, Anette , 2015, In: Molecular Pharmaceutics. 12, 11, p. 4067-4076 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Precipitation of a poorly soluble model drug during in vitro lilpolysis: characterization and dissolution of the precipitate

    Sassene, P. J., Knopp, Matthias Manne, Hesselkilde, J. Z., Koradia, V., Larsen, A., Rades, Thomas & Mullertz, Anette , 2010, In: Journal of Pharmaceutical Sciences. 99, 12, p. 4982-4991

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Comparison of lipases for in vitro models of gastric digestion: lipolysis using two infant formulas as model substrates

    Sassene, P. J., Fanø, M., Mu, Huiling, Rades, Thomas, Aquistapace, S., Schmitt, B., Cruz-Hernandez, C., Wooster, T. J. & Mullertz, Anette , 14 Sep 2016, In: Food & Function. 7, 9, p. 3989-3998 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    In Vivo Precipitation of Poorly Soluble Drugs from Lipid-Based Drug Delivery Systems

    Sassene, P. J., Michaelsen, M. H., Mosgaard, M. D., Klitgaard, Mette, Van Den Broek, E., Wasan, K. M., Mu, Huiling, Rades, Thomas & Mullertz, Anette , 3 Oct 2016, In: Molecular Pharmaceutics. 13, 10, p. 3417-3426 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Applications of Raman spectroscopy in aqueous environments

    Sandler, N., Savolainen, M., Saupe, A., Strachan, C. & Rades, Thomas, 2007, In: Pharmaceutical Technology Europe.

    Research output: Contribution to journal › Journal article › Research

  34. Published

    Microcontainers for oral insulin delivery - in vitro studies of permeation enhancement

    Rune Jørgensen, J., Leth Jepsen, M., Hagner Nielsen, L., Dufva, M., Nielsen, Hanne Mørck, Rades, Thomas, Boisen, A. & Mullertz, Anette , 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 143, p. 98-105

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    The significance of the amorphous potential energy landscape for dictating glassy dynamics and driving solid-state crystallisation

    Ruggiero, M. T., Krynski, M., Kissi, E. O., Sibik, J., Markl, D., Tan, N. Y., Arslanov, D., van der Zande, W., Redlich, B., Korter, T. M., Grohganz, Holger, Löbmann, Korbinian, Rades, Thomas, Elliott, S. R. & Zeitler, J. A., 2017, In: Physical chemistry chemical physics : PCCP. 19, 44, p. 30039-30047

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Immune responses induced by nano-self-assembled lipid adjuvants based on a monomycoloyl glycerol analogue after vaccination with the Chlamydia trachomatis major outer membrane protein

    Rodrigues, L., Raftopoulos, K. N., Tandrup Schmidt, S., Schneider, F., Dietz, H., Rades, Thomas, Franzyk, Henrik, Pedersen, Anders Elm, Papadakis, C. M., Christensen, D., Winter, G., Foged, Camilla & Hubert, M., 10 Sep 2018, In: Journal of controlled release : official journal of the Controlled Release Society. 285, p. 12-22 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Monitoring the Isothermal Dehydration of Crystalline Hydrates Using Low-Frequency Raman Spectroscopy

    Robert, C., Fraser-Miller, S. J., Bērziņš, Kārlis, Okeyo, P. O., Rantanen, Jukka, Rades, Thomas & Gordon, K. C., 2021, In: Molecular Pharmaceutics. 18, 3, p. 1264-1276

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Bicontinuous cubic liquid crystals as sustained delivery systems for peptides and proteins

    Rizwan, S. B., Boyd, B. J., Rades, Thomas & Hook, S., 2010, In: Expert Opinion on Drug Delivery. 7, 10, p. 1133-44 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Characterisation of bicontinuous cubic liquid crystalline systems of phytantriol and water using cryo field emission scanning electron microscopy (cryo FESEM)

    Rizwan, S. B., Dong, Y., Boyd, Ben, Rades, Thomas & Hook, S., 2007, In: Micron.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Cubosomes contaning the adjuvants imiquimod and monophosphryl lipid A stimulate robust cellular and humoral immune respones

    Rizwan, S. B., McBurney, W. T., Young, K., Boyd, B. J., Rades, Thomas & Hook, B., 2013, In: Journal of Controlled Release. 165, 1, p. 16-21

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Preparation of phytantriol cubosomes by solvent precursor dilution for the delivery of protein vaccines

    Rizwan, S. B., Assmus, D., Boehnke, A., Hanley, T., Boyd, Ben, Rades, Thomas & Hook, S., Sep 2011, In: European Journal of Pharmaceutics and Biopharmaceutics. 79, 1, p. 15-22 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Liquid crystalline systems of phytantriol and glyceryl monooleate containing a hydrophilic protein: Characterisation, swelling and release kinetics

    Rizwan, S. B., Hanley, T., Boyd, Ben, Rades, Thomas & Hook, S., Nov 2009, In: Journal of Pharmaceutical Sciences. 98, 11, p. 4191-4204 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Elucidating the Dehydration Mechanism of Nitrofurantoin Monohydrate II Using Low-Frequency Raman Spectroscopy

    Remoto, P. J. G., Bērziņš, Kārlis, Fraser-Miller, S. J., Korter, T. M., Rades, Thomas, Rantanen, Jukka & Gordon, K. C., 2022, In: Crystal Growth and Design. 22, 4, p. 2733-2741

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Exploring the Solid-State Landscape of Carbamazepine during Dehydration: A Low Frequency Raman Spectroscopy Perspective

    Remoto, P. I. I. I. J. G., Bērziņš, Kārlis, Fraser-Miller, S. J., Korter, T. M., Rades, Thomas, Rantanen, Jukka & Gordon, K. C., 2023, In: Pharmaceutics. 15, 5, 15 p., 1526.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    A case study of real-time monitoring of solid-state phase transformations in acoustically levitated particles using near infrared and Raman spectroscopy

    Rehder, S., Wu, J., Laackmann, J., Moritz, H., Rantanen, Jukka, Rades, Thomas & Leopold, C. S., 2013, In: European Journal of Pharmaceutical Sciences. 48, 1-2, p. 97-103 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    High-shear granulation as a manufacturing method for cocrystal granules

    Rehder, S., Christensen, N. P. A., Rantanen, Jukka, Rades, Thomas & Leopold, C. S., Nov 2013, In: European Journal of Pharmaceutics and Biopharmaceutics. 85, 3, Part B, p. 1019-30 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Investigation of the formation process of two piracetam cocrystals during grinding

    Rehder, S., Klukkert, M., Löbmann, Korbinian, Strachan, C. J., Sakmann, A., Gordon, K., Rades, Thomas & Leopold, C. S., 2011, In: Pharmaceutics. 3, 4, p. 706-722 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Thermal degradation of amorphous glibenclamide

    Rehder, S., Sakmann, A., Rades, Thomas & Leopold, C. S., Jan 2012, In: European Journal of Pharmaceutics and Biopharmaceutics. 80, 1, p. 203-208 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Towards characterization and identification of solid state pharmaceutical mixtures through second harmonic generation

    Rawle, C. B., Lee, C. J., Strachan, C. J., Payne, K., Manson, P. J. & Rades, Thomas, 2006, In: Journal of Pharmaceutical Sciences. 95, 4, p. 761-8 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Transcutaneous immunization using microneedles and cubosomes: Mechanistic investigations using Optical Coherence Tomography and Two-Photon Microscopy

    Rattanapak, T., Birchall, J., Young, K., Ishii, M., Meglinski, I., Rades, Thomas & Hook, S., 28 Dec 2013, In: Journal of controlled release : official journal of the Controlled Release Society. 172, 3, p. 894-903 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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