Thomas Rades

Thomas Rades

Professor

ORCID: 0000-0002-7521-6020

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  1. Published

    Design and optimization of self-nanoemulsifying drug delivery systems of clove oil for efficacy enhancement in fish anesthesia

    Kheawfu, Pikulkaew, Rades, Thomas, Mullertz, Anette , Jørgensen, Louise von Gersdorff & Okonogi, 2021, In: Journal of Drug Delivery Science and Technology. 61, 9 p., 102241.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Development and characterization of clove oil nanoemulsions and self-microemulsifying drug delivery systems

    Kheawfu, K., Pikulkaew, S., Rades, Thomas, Mullertz, Anette & Okonogi, S., 2018, In: Journal of Drug Delivery Science and Technology. 46, p. 330-338 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Elucidating Pathway and Anesthetic Mechanism of Action of Clove Oil Nanoformulations in Fish

    Kheawfu, K., Pikulkaew, S., Wellendorph, Petrine, Jørgensen, Louise von Gersdorff, Rades, Thomas, Mullertz, Anette & Okonogi, S., 2022, In: Pharmaceutics. 14, 5, 13 p., 919.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    The Precipitation Behavior of Poorly Water-Soluble Drugs with an Emphasis on the Digestion of Lipid Based Formulations

    Khan, J., Rades, Thomas & Boyd, B., Mar 2016, In: Pharmaceutical Research. 33, 3, p. 548-62 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    In Situ Lipolysis and Synchrotron Small-Angle X-ray Scattering for the Direct Determination of the Precipitation and Solid-State Form of a Poorly Water-Soluble Drug During Digestion of a Lipid-Based Formulation

    Khan, J., Hawley, A., Rades, Thomas & Boyd, B. J., Sep 2016, In: Journal of Pharmaceutical Sciences. 105, 9, p. 2631-2639 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Addition of Cationic Surfactants to Lipid-Based Formulations of Poorly Water-Soluble Acidic Drugs Alters the Phase Distribution and the Solid-State Form of the Precipitate Upon In Vitro Lipolysis

    Khan, J., Rades, Thomas & Boyd, Ben, Sep 2018, In: Journal of Pharmaceutical Sciences. 107, 9, p. 2420-2427 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Lipid-Based Formulations Can Enable the Model Poorly Water-Soluble Weakly Basic Drug Cinnarizine to Precipitate in an Amorphous-Salt Form during in Vitro Digestion

    Khan, J., Rades, Thomas & Boyd, B. J., 2016, In: Molecular Pharmaceutics. 13, 11, p. 3783-3793 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Development of a novel magnetic resonance imaging contrast agent for pressure measurements using lipid-coated microbubbles

    Kaur, R., Morris, R., Bencsik, M., Vangala, A., Rades, Thomas & Perrie, Y., 2009, In: Journal of Biomedical Nanotechnology. 5, 6, p. 707-15 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Process Optimization and Upscaling of Spray-Dried Drug-Amino acid Co-Amorphous Formulations

    Kasten, G., Duarte, Í., Paisana, M., Löbmann, Korbinian, Rades, Thomas & Grohganz, Holger, 9 Jan 2019, In: Pharmaceutics. 11, 1, 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    In vitro and in vivo comparison between crystalline and co-amorphous salts of naproxen-arginine

    Kasten, G., Lobo, L., Dengale, S., Grohganz, Holger, Rades, Thomas & Löbmann, Korbinian, 1 Nov 2018, In: European Journal of Pharmaceutics and Biopharmaceutics. 132, p. 192-199 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Development of a screening method for co-amorphous formulations of drugs and amino acids

    Kasten, G., Grohganz, Holger, Rades, Thomas & Löbmann, Korbinian, Dec 2016, In: European Journal of Pharmaceutical Sciences. 95, p. 28-35 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Performance comparison between crystalline and co-amorphous salts of indomethacin-lysine

    Kasten, G., Nouri, K., Grohganz, Holger, Rades, Thomas & Löbmann, Korbinian, 25 Nov 2017, In: International Journal of Pharmaceutics. 533, 1, p. 138-144 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Co-former selection for co-amorphous drug-amino acid formulations

    Kasten, G., Löbmann, Korbinian, Grohganz, Holger & Rades, Thomas, 2019, In: International Journal of Pharmaceutics. 557, p. 366-373

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Effect of different preparation methods on the dissolution behaviour of amorphous indomethacin

    Karmwar, P., Graeser, K., Gordon, K. C., Strachan, C. J. & Rades, Thomas, Feb 2012, In: European Journal of Pharmaceutics and Biopharmaceutics. 80, 2, p. 459-464 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Investigation of properties and recrystallisation behaviour of amorphous indomethacin samples prepared by different methods

    Karmwar, P., Graeser, K., Gordon, K. C., Strachan, C. J. & Rades, Thomas, 30 Sep 2011, In: International Journal of Pharmaceutics. 417, 1-2, p. 94-100 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Determining Thermal Conductivity of Small Molecule Amorphous Drugs with Modulated Differential Scanning Calorimetry and Vacuum Molding Sample Preparation

    Karl, M., Rantanen, Jukka & Rades, Thomas, 6 Dec 2019, In: Pharmaceutics. 11, 12, 7 p., 670.

    Research output: Contribution to journal › Journal article › Communication

  17. Published

    Temperature-Modulated Micromechanical Thermal Analysis with Microstring Resonators Detects Multiple Coherent Features of Small Molecule Glass Transition

    Karl, M., Thamdrup, L. H. E., Rantanen, Jukka, Boisen, A. & Rades, Thomas, 2020, In: Sensors. 20, 4, 14 p., 1019.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Ultra Sensitive Micro String Resonators for Solid State Thermomechanical Analysis of Small and Large Molecules

    Karl, M., Larsen, P. E., Rangacharya, V., Hwu, E. T., Rantanen, Jukka, Boisen, A. & Rades, Thomas, 19 Dec 2018, In: Journal of the American Chemical Society. 140, 50, p. 17522-17531

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Measurement of amorphous indomethacin stability with NIR and Raman spectroscopy

    Kao, J. Y., McGoverin, C. M., Graeser, K. A., Rades, Thomas & Gordon, K. C., Jan 2012, In: Vibrational Spectroscopy. 58, p. 19-26 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Lysozyme-magnesium aluminum silicate microparticles: Molecular interaction, bioactivity and release studies

    Kanjanakawinkul, W., Medlicott, N. J., Rades, Thomas, Puttipipatkhachorn, S. & Pongjanyakul, T., Sep 2015, In: International Journal of Biological Macromolecules. 80, p. 651-658 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Nicotine-magnesium aluminum silicate microparticle surface modified with chitosan for mucosal delivery

    Kanjanakawinkul, W., Rades, Thomas, Puttipipatkhachorn, S. & Pongjanyakul, T., 1 Apr 2013, In: Materials science & engineering. C, Materials for biological applications. 33, 3, p. 1727-36 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Rapid and specific high-performance liquid chromatography for the in vitro quantification of D-Lys6-GnRH in a microemulsion-type formulation in the presence of peptide oxidation products

    Kafka, A. P., Rades, Thomas & McDowell, A., Feb 2010, In: Biomedical Chromatography. 24, 2, p. 132-139 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Histidine residues in the peptide D-Lys6-GnRH: Potential for copolymerization in polymeric nanoparticles

    Kafka, A. P., Kleffmann, T., Rades, Thomas & McDowell, A., 5 Oct 2009, In: Molecular Pharmaceutics. 6, 5, p. 1483-1491 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Characterization of Peptide Polymer Interactions in Poly(alkylcyanoacrylate) Nanoparticles: A Mass Spectrometric Approach

    Kafka, A. P., Kleffmann, T., Rades, Thomas & McDowell, A., 2010, In: Current Drug Delivery.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. The application of MALDI TOF MS in biopharmaceutical research

    Kafka, A. P., Kleffmann, T., Rades, Thomas & McDowell, A., 2011, In: International Journal of Pharmaceutics. 417, 1-2, p. 70-82 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Release and bioactivity of PACA nanoparticles containing D-Lys6-GnRH for brushtail possum fertility control

    Kafka, A. P., McLeod, B. J., Rades, Thomas & McDowell, A., 2011, In: Journal of controlled release : official journal of the Controlled Release Society. 149, 3, p. 307-13 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    In vitro-in vivo relationship for amorphous solid dispersions using a double membrane dissolution-permeation setup

    Jørgensen, J. R., Mohr, W., Rischer, M., Sauer, A., Mistry, S., Rades, Thomas & Mullertz, Anette , 2023, In: European Journal of Pharmaceutics and Biopharmaceutics. 188, p. 26-32

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Stability and intrinsic dissolution of vacuum compression molded amorphous solid dispersions of efavirenz

    Jørgensen, J. R., Mohr, W., Rischer, M., Sauer, A., Mistry, S., Mullertz, Anette & Rades, Thomas, 2023, In: International Journal of Pharmaceutics. 632, 8 p., 122564.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    In Vitro, Ex Vivo and In Vivo Evaluation of Microcontainers for Oral Delivery of Insulin

    Jørgensen, J. R., Yu, F., Ramakrishnan, V., Nielsen, L. H., Nielsen, Hanne Mørck, Boisen, A., Rades, Thomas & Mullertz, Anette , 7 Jan 2020, In: Pharmaceutics. 12, 1, 14 p., 48.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Design of a self-unfolding delivery concept for oral administration of macromolecules

    Jørgensen, J. R., Thamdrup, L. H. E., Kamguyan, K., Nielsen, L. H., Nielsen, Hanne Mørck, Boisen, A., Rades, Thomas & Mullertz, Anette , 2021, In: Journal of Controlled Release. 329, p. 948-954

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Aerosol OT microemulsions as carriers for transdermal delivery of hydrophobic and hydrophilic local anesthetics

    Junyaprasert, V. B., Boonme, P., Wurster, D. E. & Rades, Thomas, 2008, In: Drug Delivery Technology. 15, 5, p. 323-30 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Transdermal delivery of hydrophobic and hydrophilic local anesthetics from o/w and w/o Brij 97-based microemulsions

    Junyaprasert, V. B., Boonme, P., Songkro, S., Krauel, K. & Rades, Thomas, 2007, In: Journal of Pharmacy and Pharmaceutical Sciences. 10, 3, p. 288-98 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Exploring the utility of the Chasing-rinciple: influence of drug-free SNEDDS composition on solubilization of carvedilol, cinnarizine and R3040 in aqueous suspension

    Jorgensen, S. D. S., Rades, Thomas, Mu, Huiling, Graeser, K. & Mullertz, Anette , Jan 2019, In: Acta Pharmaceutica Sinica B. 9, 1, p. 194-201

    Research output: Contribution to journal › Letter › Research › peer-review

  34. Published

    The ability of two in vitro lipolysis models reflecting the human and rat gastro-intestinal conditions to predict the in vivo performance of SNEDDS dosing regimens

    Jorgensen, S. D. S., Al Sawaf, M., Graeser, K., Mu, Huiling, Mullertz, Anette & Rades, Thomas, Mar 2018, In: European Journal of Pharmaceutics and Biopharmaceutics. 124, p. 116-124

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Themed issue: Applications of novel spectroscopic techniques to pharmaceutical systems

    Jones, D. S. & Rades, Thomas, Feb 2007, In: Journal of Pharmacy and Pharmacology. 59, 2, p. 145-146 2 p.

    Research output: Contribution to journal › Editorial › Research › peer-review

  36. Published

    Characterization of the hydrodynamics in a miniaturized dissolution apparatus

    Johansson, Kristoffer Enøe, Plum, J., Mosleh, M., Madsen, C. M., Rades, Thomas & Mullertz, Anette , 2018, In: Journal of Pharmaceutical Sciences. 107, 4, p. 1095-1103 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Amorphous is not always better—A dissolution study on solid state forms of carbamazepine

    Jensen, L. G., Skautrup, F. B., Mullertz, Anette , Abrahamsson, B., Rades, Thomas & Priemel, P. A., 30 Apr 2017, In: International Journal of Pharmaceutics. 522, 1-2, p. 74-79 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Formation mechanism of coamorphous drug−amino acid mixtures

    Jensen, K. B. T., Larsen, F. H., Cornett, Claus, Löbmann, Korbinian, Grohganz, Holger & Rades, Thomas, 2015, In: Molecular Pharmaceutics. 12, 7, p. 2484−2492 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Improving co-amorphous drug formulations by the addition of the highly water soluble amino acid proline

    Jensen, K. B. T., Löbmann, Korbinian, Rades, Thomas & Grohganz, Holger, 2014, In: Pharmaceutics. 6, 3, p. 416-435 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Influence of variation in molar ratio on co-amorphous drug-amino acid systems

    Jensen, K. B. T., Larsen, F. H., Löbmann, Korbinian, Rades, Thomas & Grohganz, Holger, 2016, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 107, p. 32-39 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Preparation and characterization of spray-dried co-amorphous drug-amino acid salts

    Jensen, K. B. T., Blaabjerg, L. I., Lenz, E., Bohr, A., Grohganz, Holger, Kleinebudde, P., Rades, Thomas & Löbmann, Korbinian, May 2016, In: The Journal of pharmacy and pharmacology. 68, 5, p. 615–624 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Physical Characterization of Synthetic Phosphatidylinositol Dimannosides and Analogues in Binary Systems with Phosphatidylcholine

    Hubert, M., Larsen, D. S., Hayman, C. M., Rades, Thomas & Hook, S., 30 Jan 2014, In: Molecular Pharmaceutics. 11, 3, p. 913-921 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Physicochemical and biological characterization of synthetic phosphatidylinositol dimannosides and analogues

    Hubert, M., Compton, B. J., Hayman, C. M., Larsen, D. S., Painter, G. F., Rades, Thomas & Hook, S., 6 May 2013, In: Molecular Pharmaceutics. 10, 5, p. 1928-39 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Immune stimulating complexes (ISCOMs) and Quil-A containing particulate formulations as vaccine delivery systems

    Hook, S. & Rades, Thomas, 1 Jan 2013, Immunomic Discovery of Adjuvants and Candidate Subunit Vaccines. Springer New York, p. 233-261 29 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  45. Published

    (Co-)amorphization of enantiomers – Investigation of the amorphization process, the physical stability and the dissolution behavior

    Holzapfel, K., Liu, J., Rades, Thomas & Leopold, C. S., 2022, In: International Journal of Pharmaceutics. 616, 9 p., 121552.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Co-amorphous systems consisting of indomethacin and the chiral co-former tryptophan: Solid-state properties and molecular mobilities

    Holzapfel, K., Rades, Thomas & Leopold, C. S., 2023, In: International Journal of Pharmaceutics. 636, 12 p., 122840.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Mechanochemical activated dry amorphisation by milling equilibrium between ap mesoporous silica

    Hoefer, H. H., Monsuur, F. H., Pauly, T., Choudhari, Y., Löbmann, Korbinian & Rades, Thomas, 2019, Patent No. US20190350855A1

    Research output: Patent

  48. Effects of film coating thickness and drug layer uniformity on in vitro drug release from sustained-release coated pellets: a case study using terahertz pulsed imaging

    Ho, L., Cuppok, Y., Muschert, S., Gordon, K. C., Pepper, M., Shen, Y., Siepmann, F., Siepmann, J., Taday, P. F. & Rades, Thomas, 2009, In: International Journal of Pharmaceutics. 382, 1-2, p. 151-9 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Terahertz pulsed imaging as an analytical tool for sustained-release tablet film coating

    Ho, L., Müller, R., Gordon, K. C., Kleinebudde, P., Pepper, M., Rades, Thomas, Shen, Y., Taday, P. F. & Zeitler, J. A., 2009, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 71, 1, p. 117-23 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Monitoring the film coating unit operation and predicting drug dissolution using terahertz pulsed imaging

    Ho, L., Müller, R., Gordon, K. C., Kleinebudde, P., Pepper, M., Rades, Thomas, Shen, Y., Taday, P. F. & Zeitler, J. A., 2009, In: Al Azhar Journal of Pharmaceutical Sciences. 98, 12, p. 4866-76 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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