Thomas Rades
Professor
Pharmaceuticals, processes and products
Universitetsparken 2
2100 København Ø
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Design and optimization of self-nanoemulsifying drug delivery systems of clove oil for efficacy enhancement in fish anesthesia
Kheawfu, Pikulkaew, Rades, Thomas, Mullertz, Anette , Jørgensen, Louise von Gersdorff & Okonogi, 2021, In: Journal of Drug Delivery Science and Technology. 61, 9 p., 102241.Research output: Contribution to journal › Journal article › Research › peer-review
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Influence of preparation method and choice of phospholipid on co-amorphization, physical stability, and dissolution behavior of equimolar indomethacin-phospholipid systems: A case study
Khorami, Keyoomars, Mullertz, Anette & Rades, Thomas, 2024, In: Journal of Drug Delivery Science and Technology. 93, 8 p., 105433.Research output: Contribution to journal › Journal article › Research › peer-review
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The Binding of Alpinia galanga Oil and Its Nanoemulsion to Mammal GABA(A) Receptors Using Rat Cortical Membranes and an In Silico Modeling Platform
Khumpirapang, N., Suknuntha, K., Wongrattanakamon, P., Jiranusornkul, S., Anuchapreeda, S., Wellendorph, Petrine, Mullertz, Anette , Rades, Thomas & Okonogi, S., 2022, In: Pharmaceutics. 14, 3, 15 p., 650.Research output: Contribution to journal › Journal article › Research › peer-review
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Formulation optimization, anesthetic activity, skin permeation, and transportation pathway of Alpinia galanga oil SNEDDS in zebrafish (Danio rerio)
Khumpirapang, N., Jørgensen, Louise von Gersdorff, Mullertz, Anette , Rades, Thomas & Okonogi, S., 2021, In: European Journal of Pharmaceutics and Biopharmaceutics. 165, p. 193-202 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Self-microemulsifying drug delivery system and nanoemulsion for enhancing aqueous miscibility of Alpinia galanga oil
Khumpirapang, N., Pikulkaew, S., Mullertz, Anette , Rades, Thomas & Okonogi, S., 2017, In: PLOS ONE. 12, 11, 18 p., e0188848.Research output: Contribution to journal › Journal article › Research › peer-review
Chitosan-magnesium aluminum silicate nanocomposite films: physicochemical characterization and drug permeability
Khunawattanakul, W., Puttipipatkhachorn, S., Rades, Thomas & Pongjanyakul, T., 2010, In: International Journal of Pharmaceutics. 393, 1-2, p. 219-29 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Chitosan-magnesium aluminum silicate composite dispersions: characterization of rheology, flocculate size and zeta potential
Khunawattanakul, W., Puttipipatkhachorn, S., Rades, Thomas & Pongjanyakul, T., 2008, In: International Journal of Pharmaceutics. 351, 1-2, p. 227-35 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Novel chitosan-magnesium aluminum silicate nanocomposite film coatings for modified-release tablets
Khunawattanakul, W., Puttipipatkhachorn, S., Rades, Thomas & Pongjanyakul, T., 2011, In: International Journal of Pharmaceutics. 407, 1-2, p. 132-41 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Determination of Stable Co-Amorphous Drug-Drug Ratios from the Eutectic Behavior of Crystalline Physical Mixtures
Kissi, E. O., Khorami, Keyoomars & Rades, Thomas, 2019, In: Pharmaceutics. 11, 11 p., 628.Research output: Contribution to journal › Journal article › Research › peer-review
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Characterising glass transition temperatures and glass dynamics in mesoporous silica-based amorphous drugs
Kissi, E. O., Ruggiero, M. T., Hempel, N. J., Song, Z., Grohganz, Holger, Rades, Thomas & Löbmann, Korbinian, 1 Jan 2019, In: Physical Chemistry Chemical Physics. 21, 35, p. 19686-19694 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Glass-Transition Temperature of the β-Relaxation as the Major Predictive Parameter for Recrystallization of Neat Amorphous Drugs
Kissi, E. O., Grohganz, Holger, Löbmann, Korbinian, Ruggiero, M. T., Zeitler, J. A. & Rades, Thomas, 15 Mar 2018, In: Journal of Physical Chemistry Part B: Condensed Matter, Materials, Surfaces, Interfaces & Biophysical. 122, 10, p. 2803-2808 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The Role of Glass Transition Temperatures in Coamorphous Drug-Amino Acid Formulations
Kissi, E. O., Kasten, G., Löbmann, Korbinian, Rades, Thomas & Grohganz, Holger, 4 Sep 2018, In: Molecular Pharmaceutics. 15, 9, p. 4247–4256Research output: Contribution to journal › Journal article › Research › peer-review
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X-ray Imaging for Gastrointestinal Tracking of Microscale Oral Drug Delivery Devices
Kjeldsen, R. B., Kristensen, M. N., Gundlach, C., Thamdrup, L. H. E., Mullertz, Anette , Rades, Thomas, Nielsen, L. H., Zór, K. & Boisen, A., 2021, In: ACS Biomaterials Science and Engineering. 7, 6, p. 2538–2547Research output: Contribution to journal › Journal article › Research › peer-review
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Assessing acute colitis induced by dextran sulfate sodium in rats and its impact on gastrointestinal fluids
Klitgaard, Mette, Kristensen, M. N., Venkatasubramanian, R., Guerra, Priscila Regina, Jacobsen, Jette, Berthelsen, R., Rades, Thomas & Mullertz, Anette , 2023, In: Drug Delivery and Translational Research. 13, p. 1484–1499Research output: Contribution to journal › Journal article › Research › peer-review
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Inhalable Antimicrobials for Treatment of Bacterial Biofilm-Associated Sinusitis in Cystic Fibrosis Patients: Challenges and Drug Delivery Approaches
Klodzinska, S. N., Priemel, P. A., Rades, Thomas & Nielsen, Hanne Mørck, 9 Oct 2016, In: International Journal of Molecular Sciences . 17, 10, 19 p., 1688.Research output: Contribution to journal › Journal article › Research › peer-review
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Combining diagnostic methods for antimicrobial susceptibility testing – A comparative approach
Klodzinska, S. N., Priemel, P. A., Rades, Thomas & Nielsen, Hanne Mørck, Jan 2018, In: Journal of Microbiological Methods. 144, p. 177-185Research output: Contribution to journal › Journal article › Research › peer-review
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Multispectral UV imaging for fast and non-destructive quality control of chemical and physical tablet attributes
Klukkert, M., Wu, J. X., Rantanen, Jukka, Carstensen, J. M., Rades, Thomas & Leopold, C. S., 2016, In: European Journal of Pharmaceutical Sciences. 90, p. 85-95 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Rapid Assessment of Tablet Film Coating Quality by Multispectral UV Imaging
Klukkert, M., Wu, J. X., Rantanen, Jukka, Rehder, S., Carstensen, J. M., Rades, Thomas & Leopold, C. S., 13 Oct 2015, In: AAPS PharmSciTech. p. 1-10 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Non-destructive Quality control of tablets and blister packs by UV imaging
Klukkert, M., Wu, J. X., Rantanen, Jukka, Rehder, S., Carstensen, J. M., Rades, Thomas & Leopold, C. S., 2016, In: Pharmazeutische Industrie. 78, 1, p. 108-120 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Influence of Tableting on the Conformation and Thermal Stability of Trypsin as a Model Protein
Klukkert, M., van de Weert, Marco, Fanø, M., Rades, Thomas & Leopold, C. S., 2015, In: Journal of Pharmaceutical Sciences. 104, 12, p. 4314–4321 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effect of amorphous phase separation and crystallization on the in vitro and in vivo performance of an amorphous solid dispersion
Knopp, Matthias Manne, Wendelboe, J., Holm, R. & Rades, Thomas, Sep 2018, In: European Journal of Pharmaceutics and Biopharmaceutics. 130, p. 290-295Research output: Contribution to journal › Journal article › Research › peer-review
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Recent advances and potential applications of modulated differential scanning calorimetry (mDSC) in drug development
Knopp, Matthias Manne, Löbmann, Korbinian, Elder, D. P., Rades, Thomas & Holm, R., 1 May 2016, In: European Journal of Pharmaceutical Sciences. 87, p. 164-173 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Influence of Polymer Molecular Weight on Drug-Polymer Solubility: A Comparison between Experimentally Determined Solubility in PVP and Prediction Derived from Solubility in Monomer
Knopp, Matthias Manne, Olesen, N. E., Holm, P., Langguth, P., Holm, R. & Rades, Thomas, 3 Mar 2015, In: Journal of Pharmaceutical Sciences. 104, 9, p. 2905–2912 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Influence of Copolymer Composition on In Vitro and In Vivo Performance of Celecoxib-PVP/VA Amorphous Solid Dispersions
Knopp, Matthias Manne, Nguyen, J. H., Mu, Huiling, Langguth, P., Rades, Thomas & Holm, R., Mar 2016, In: The A A P S Journal. 18, 2, p. 416-23 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effect of polymer type and drug dose on the in vitro and in vivo behavior of amorphous solid dispersions
Knopp, Matthias Manne, Chourak, N., Khan, F., Wendelboe, J., Langguth, P., Rades, Thomas & Holm, R., Aug 2016, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 105, p. 106-14 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Statistical Analysis of a Method to Predict Drug-Polymer Miscibility
Knopp, Matthias Manne, Olesen, N. E., Huang, Y., Holm, R. & Rades, Thomas, 5 Jan 2016, In: Journal of Pharmaceutical Sciences. 105, 1, p. 362–367 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Influence of polymer molecular weight on in vitro dissolution behavior and in vivo performance of celecoxib:PVP amorphous solid dispersions
Knopp, Matthias Manne, Nguyen, J. H., Becker, C., Francke, N. M., Jørgensen, E. B., Holm, P., Holm, R., Mu, Huiling, Rades, Thomas & Langguth, P., Apr 2016, In: European Journal of Pharmaceutics and Biopharmaceutics. 101, p. 145-51 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Evaluation of drug-polymer solubility curves through formal statistical analysis: comparison of preparation techniques
Knopp, Matthias Manne, Olesen, N. E., Holm, P., Löbmann, Korbinian, Holm, R., Langguth, P. & Rades, Thomas, Jan 2015, In: Journal of Pharmaceutical Sciences. 104, 1, p. 44-51 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A Promising New Method to Estimate Drug-Polymer Solubility at Room Temperature
Knopp, Matthias Manne, Gannon, N., Porsch, I., Rask, M. B., Olesen, N. E., Langguth, P., Holm, R. & Rades, Thomas, Sep 2016, In: Journal of Pharmaceutical Sciences. 105, 9, p. 2621-2624 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Comparative Study of Different Methods for the Prediction of Drug-Polymer Solubility
Knopp, Matthias Manne, Tajber, L., Tian, Y., Olesen, N. E., Jones, D. S., Kozyra, A., Löbmann, Korbinian, Paluch, K., Brennan, C. M., Holm, R., Healy, A. M., Andrews, G. P. & Rades, Thomas, 8 Sep 2015, In: Molecular Pharmaceutics. 12, 9, p. 3408-19 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Investigating dehydration from compacts using terahertz pulsed, raman, and near-infrared spectroscopy
Kogermann, K., Zeitler, A. J., Rantanen, Jukka, Rades, Thomas, Taday, P. F., Pepper, M., Heinämäki, J. & Strachan, C. J., 2007, In: Applied Spectroscopy. 61, 12, p. 1265-1274Research output: Contribution to journal › Journal article › Research › peer-review
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Development and characterisation of modified poloxamer 407 thermoresponsive depot systems containing cubosomes
Kojarunchitt, T., Hook, S., Rizwan, S., Rades, Thomas & Baldursdottir, S., 2011, In: International Journal of Pharmaceutics. 408, 1-2, p. 20-26 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Modified thermoresponsive Poloxamer 407 and chitosan sol-gels as potential sustained-release vaccine delivery systems
Kojarunchitt, T., Baldursdottir, S., Dong, Y., Boyd, B. J., Rades, Thomas & Hook, S., Jan 2015, In: European Journal of Pharmaceutics and Biopharmaceutics. 89, p. 74-81 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Solventless amorphization and pelletization using a high shear granulator. Part I; feasibility study using indomethacin
Kondo, K. & Rades, Thomas, 2022, In: European Journal of Pharmaceutics and Biopharmaceutics. 181, p. 147-158Research output: Contribution to journal › Journal article › Research › peer-review
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Solventless amorphization and pelletization using a high shear granulator. Part II; Preparation of co-amorphous mixture-layered pellets using indomethacin and arginine
Kondo, K. & Rades, Thomas, 2022, In: European Journal of Pharmaceutics and Biopharmaceutics. 181, p. 183-194Research output: Contribution to journal › Journal article › Research › peer-review
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Using different structure types of microemulsions for the preparation of poly(alkylcyanoacrylate) nanoparticles by interfacial polymerization
Krauel, K., Davies, N. M., Hook, S. & Rades, Thomas, 18 Aug 2005, In: Journal of Controlled Release. 106, 1-2, p. 76-87 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Characterisation of colloidal drug delivery systems from the naked eye to Cryo-FESEM
Krauel, K., Girvan, L., Hook, S. & Rades, Thomas, 2007, In: Micron. 38, 8, p. 796-803 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Entrapment of bioactive molecules in poly (alkylcyanoacrylate) nanoparticles
Krauel, K., Pitaksuteepong, T., Davies, N. M. & Rades, Thomas, 2004, In: American Journal of Drug Delivery. 2, 4, p. 251-259 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Preparation of poly (alkylcyanoacrylate) nanoparticles by polymerization of water-free microemulsions
Krauel, K., Graf, A., Hook, S. M., Davies, N. M. & Rades, Thomas, 2006, In: Journal of Microencapsulation. 23, 5, p. 499-512 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Impact of oral gavage technique of drug-containing microcontainers on the gastrointestinal transit and absorption in rats
Kristensen, M. N., Rades, Thomas, Boisen, A. & Mullertz, Anette , 2022, In: International Journal of Pharmaceutics. 618, 121630.Research output: Contribution to journal › Journal article › Research › peer-review
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Nanomechanical Infrared Spectroscopy with Vibrating Filters for Pharmaceutical Analysis
Kurek, M., Carnoy, M., Larsen, P. E., Nielsen, L. H., Hansen, O., Rades, Thomas, Schmid, S. & Boisen, A., 27 Mar 2017, In: Angewandte Chemie (International ed. in English). 56, 14, p. 3901-3905 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
A method for the incorporation of ovalbumin into immune stimulating complexes prepared by the hydration method
Könnings, S., Copland, M. J., Davies, N. M. & Rades, Thomas, 25 Jul 2002, In: International Journal of Pharmaceutics. 241, 2, p. 385-9 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Utilizing nanoparticles for improving anti-biofilm effects of azithromycin: A head-to-head comparison of modified hyaluronic acid nanogels and coated poly (lactic-co-glycolic acid) nanoparticles
Kłodzińska, S. N., Wan, F., Jumaa, H., Sternberg, C., Rades, Thomas & Nielsen, Hanne Mørck, 1 Nov 2019, In: Journal of Colloid and Interface Science. 555, p. 595-606 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Hyaluronic acid-based nanogels improve in vivo compatibility of the anti-biofilm peptide DJK-5
Kłodzińska, S. N., Pletzer, D., Rahanjam, N., Rades, Thomas, Hancock, R. E. W. & Nielsen, Hanne Mørck, 2019, In: Nanomedicine: Nanotechnology, Biology, and Medicine. 20, 102022.Research output: Contribution to journal › Journal article › Research › peer-review
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Spray-drying of inhalable, multifunctional formulations for the treatment of biofilms formed in cystic fibrosis
Lababidi, N., Kissi, E. O., Elgaher, W. A. M., Sigal, V., Haupenthal, J., Schwarz, B. C., Hirsch, A. K. H., Rades, Thomas & Schneider, M., 28 Nov 2019, In: Journal of Controlled Release. 314, p. 62-71Research output: Contribution to journal › Journal article › Research › peer-review
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Amino acids as co-amorphous excipients for simvastatin and glibenclamide: physical properties and stability
Laitinen, R., Löbmann, Korbinian, Grohganz, Holger, Strachan, C. & Rades, Thomas, 7 Jul 2014, In: Molecular Pharmaceutics. 11, 7, p. 2381-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Emerging trends in the stabilization of amorphous drugs
Laitinen, R., Löbmann, Korbinian, Strachan, C. J., Grohganz, Holger & Rades, Thomas, 30 Aug 2013, In: International Journal of Pharmaceutics. 453, 1, p. 65-79 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Supersaturating drug delivery systems: The potential of co-amorphous drug formulations
Laitinen, R., Löbmann, Korbinian, Grohganz, Holger, Priemel, P., Strachan, C. J. & Rades, Thomas, 30 Oct 2017, In: International Journal of Pharmaceutics. 532, 1, p. 1-12 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Theoretical Considerations in Developing Amorphous Solid Dispersions
Laitinen, R., Priemel, P. A., Surwase, S., Graeser, K., Strachan, C. J., Grohganz, Holger & Rades, Thomas, 2014, Amorphous Solid Dispersions - Theory and Practice. Shah, N., Sandhu, H., Choi, D. S., Chokshi, H. & Malick, A. W. (eds.). New York: Springer Science+Business Media, p. 35-90 56 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Nonlinear optics as a method for materials characterisation
Lee, C. J., Strachan, C. J., Rades, Thomas & Manson, P. J., 2007Research output: Book/Report › Book › Research › peer-review
ID: 38132533
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Analysis of 3D Prints by X-ray Computed Microtomography and Terahertz Pulsed Imaging
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The significance of the amorphous potential energy landscape for dictating glassy dynamics and driving solid-state crystallisation
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314
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Comparison of lipases for in vitro models of gastric digestion: lipolysis using two infant formulas as model substrates
Research output: Contribution to journal › Journal article › Research › peer-review
Published