Kasper Dyrberg Rand

Kasper Dyrberg Rand

Professor


  1. Published

    Glycine Perturbs Local and Global Conformational Flexibility of a Transmembrane Helix

    Högel, P., Götz, A., Kuhne, F., Ebert, M., Stelzer, W., Rand, Kasper Dyrberg, Scharnagl, C. & Langosch, D., 27 Feb 2018, In: Biochemistry. 57, 8, p. 1326-1337 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Hydrogen atom scrambling in selectively labeled anionic peptides upon collisional activation by MALDI tandem time-of-flight mass spectrometry

    Bache, N., Rand, Kasper Dyrberg, Roepstorff, P., Ploug, Michael & Jørgensen, T., 2008, In: Journal of The American Society for Mass Spectrometry. 19, 12, p. 1719-25 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Hydrogen exchange: A sensitive analytical window into protein conformation and dynamics

    Jensen, P. F. & Rand, Kasper Dyrberg, Mar 2016, Hydrogen Exchange Mass Spectrometry of protein: Fundamentals, Methods and Applications. Weis, D. (ed.). Wiley, p. 1-17 17 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  4. Published

    Hydrogen-Deuterium Exchange Mass Spectrometry (HDX-MS) Centroid Data Measured between 3.6 degrees C and 25.4 degrees C for the Fab Fragment of NISTmAb

    Hudgens, J. W., Gallagher, E. S., Karageorgos, I., Anderson, K. W., Huang, R. Y-C., Chen, G., Bou-Assaf, G. M., Espada, A., Chalmers, M. J., Harguindey, E., Zhang, H-M., Walters, B. T., Zhang, J., Venable, J., Steckler, C., Park, I., Brock, A., Lu, X., Pandey, R., Chandramohan, A. & 16 others, Anand, G. S., Nirudodhi, S. N., Sperry, J. B., Rouse, J. C., Carroll, J. A., Rand, Kasper Dyrberg, Leurs, U., Weis, D. D., Al-Naqshabandi, M. A., Hageman, T. S., Deredge, D., Wintrode, P. L., Papanastasiou, M., Lambris, J. D., Li, S. & Urata, S., 2 May 2019, In: Journal of Research of the National Institute of Standards and Technology. 124, 7 p., 124009.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Hydrogen-Deuterium Exchange Mass Spectrometry with Integrated Size-Exclusion Chromatography for Analysis of Complex Protein Samples

    Calvaresi, V., Redsted, A., Norais, N. & Rand, Kasper Dyrberg, 2021, In: Analytical Chemistry. 93, 33, p. 11406–11414

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Hydrogen/Deuterium Exchange Mass Spectrometry with Integrated Electrochemical Reduction and Microchip-Enabled Deglycosylation for Epitope Mapping of Heavily Glycosylated and Disulfide-Bonded Proteins

    Comamala, G., Krogh, C. C., Nielsen, V. S., Kutter, Jörg P., Voglmeir, J. & Rand, Kasper Dyrberg, 2021, In: Analytical Chemistry. 93, 49, p. 16330–16340

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Hydrogen/deuterium exchange mass spectrometry with improved electrochemical reduction enables comprehensive epitope mapping of a therapeutic antibody to the cysteine-knot containing vascular endothelial growth factor

    Comamala, G., Wagner, C., de la Torre, P. S., Jakobsen, R. U., Hilger, M., Brouwer, H. & Rand, Kasper Dyrberg, 8 Jun 2020, In: Analytica Chimica Acta. 1115, p. 41-51 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Improving the Sequence Coverage of Integral Membrane Proteins during Hydrogen/Deuterium Exchange Mass Spectrometry Experiments

    Möller, I. R., Slivacka, M., Hausner, J., Nielsen, A. K., Pospisilova, E., Rand, Kasper Dyrberg, Liskova, R., Polak, M., Loland, Claus Juul, Kadek, A., Man, P. & Rand, Kasper Dyrberg, 2019, In: Analytical Chemistry. 91, 17, p. 10970-10978 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Installation, validation, and application examples of two instrumental setups for gas-phase HDX-MS analysis of peptides and proteins

    Mistarz, U. H. & Rand, Kasper Dyrberg, 15 Jul 2018, In: Methods. 144, p. 113-124

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Interlaboratory Comparison of Hydrogen-Deuterium Exchange Mass Spectrometry Measurements of the Fab fragment of NISTmAb

    Hudgens, J. W., Gallagher, E. S., Karageorgos, I., Anderson, K. W., Filliben, J. J., Huang, R. Y-C., Chen, G., Bou-Assaf, G. M., Espada, A., Chalmers, M. J., Harguindey, E., Zhang, H-M., Walters, B. T., Zhang, J., Venable, J. D., Steckler, C., Park, I., Brock, A., Lu, X., Pandey, R. K. & 17 others, Chandramohan, A., Anand, G. S., Nirudodhi, S. N., Sperry, J. B., Rouse, J. C., Carroll, J. A., Rand, Kasper Dyrberg, Leurs, U., Weis, D. D., Al-Naqshabandi, M. A., Hageman, T. S., Deredge, D., Wintrode, P. L., Papanastasiou, M., Lambris, J. D., Li, S. & Urata, S., 2019, In: Analytical Chemistry. 91, 11, p. 7336-7345

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Investigating surrogate cerebrospinal fluid matrix compositions for use in quantitative LC-MS analysis of therapeutic antibodies in the cerebrospinal fluid

    Fogh, J. R., Jacobsen, A., Nguyen, T. T. T. N., Rand, Kasper Dyrberg & Olsen, L. R., 2020, In: Analytical and Bioanalytical Chemistry. 412, p. 1653-1661

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Investigating the Conformational Response of the Sortilin Receptor upon Binding Endogenous Peptide- and Protein Ligands by HDX-MS

    Trabjerg, Esben, Abu-Asad, N., Wan, Z., Kartberg, F., Christensen, S. & Rand, Kasper Dyrberg, 2 Jul 2019, In: Structure. 27, 7, p. 1103-1113.e3

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Investigating the Interaction between the Neonatal Fc Receptor and Monoclonal Antibody Variants by Hydrogen/Deuterium Exchange Mass Spectrometry

    Jensen, P. F., Larraillet, V., Schlothauer, T., Kettenberger, H., Hilger, M. & Rand, Kasper Dyrberg, Jan 2015, In: Molecular and Cellular Proteomics. 14, 1, p. 148-61 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Investigating the Role of Artemin Glycosylation

    Danwen, Q., Code, C., Quan, C., Gong, B., Arndt, J., Pepinsky, B., Rand, Kasper Dyrberg & Houde, D., Jun 2016, In: Pharmaceutical Research. 33, 6, p. 1383-1398 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Investigating the utility of minimized sample preparation and high-resolution mass spectrometry for quantification of monoclonal antibody drugs

    Nguyen, T. T. T. N., Mistarz, U. H., Costa, N., Herbet, A., Boquet, D., Becher, F. & Rand, Kasper Dyrberg, 10 Sep 2018, In: Journal of Pharmaceutical and Biomedical Analysis. 159, p. 384-392

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Investigation of amide hydrogen back-exchange in Asp and His repeats measured by hydrogen (1H/2H) exchange mass spectrometry

    Rand, Kasper Dyrberg, Lund, F. W., Amon, S. & Jørgensen, Thomas, Apr 2011, In: International Journal of Mass Spectrometry.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Loss of ammonia during electron-transfer dissociation of deuterated peptides as an inherent gauge of gas-phase hydrogen scrambling

    Rand, Kasper Dyrberg, Zehl, M., Jensen, O. & Jørgensen, T., 2010, In: Analytical Chemistry. 82, 23, p. 9755-62 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Mapping the interactions of selective biochemical probes of antibody conformation by hydrogen-deuterium exchange mass spectrometry

    Leurs, U., Beck, H., Bonnington, L., Lindner, I., Pol, E. & Rand, Kasper Dyrberg, 1 Jun 2017, In: ChemBioChem. 18, 11, p. 1016-1021

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Massespektrometri viser vejen til forbedrede proteinlægemidler

    Song, H. & Rand, Kasper Dyrberg, 2012, In: Lægemiddelforskning. 2012, p. 43-46

    Research output: Contribution to journalJournal articleCommunication

  20. Published

    Measuring the binding interfaces of protein complexes by gas-phase hydrogen/deuterium exchange mass spectrometry (gas-phase HDX-MS)

    Mistarz, U. H., Brown, J. M., Haselmann, K. F. & Rand, Kasper Dyrberg, 2015.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  21. Published

    Measuring the hydrogen/deuterium exchange of proteins at high spatial resolution by mass spectrometry: overcoming gas-phase hydrogen/deuterium scrambling

    Rand, Kasper Dyrberg, Zehl, M. & Jørgensen, T. J. D., 21 Oct 2014, In: Accounts of Chemical Research. 47, 10, p. 3018-27 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Molecular Basis of the Mechanisms Controlling MASTL

    Hermida, D., Mortuza, G. B., Pedersen, A., Pozdnyakova, I., Nguyen, T. T. T. N., Maroto, M., Williamson, M., Ebersole, T., Cazzamali, G., Rand, Kasper Dyrberg, Olsen, Jesper Velgaard, Malumbres, M. & Montoya, Guillermo, 2020, In: Molecular & Cellular Proteomics. 19, 2, p. 326-343

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Molecular analysis of the interaction between the hematopoietic master transcription factors GATA-1 and PU.1.

    Liew, C. W., Rand, Kasper Dyrberg, Simpson, R. J. Y., Yung, W. W., Mansfield, R. E., Crossley, M., Proetorius-Ibba, M., Nerlov, C., Poulsen, F. M. & Mackay, J. P., 2006, In: Journal of Biological Chemistry. 281, 38, p. 28296-306 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Molecular architecture of the Jumonji C family histone demethylase KDM5B

    Dorosz, J., Kristensen, L. H., Aduri, N. G., Mirza, Osman Asghar, Lousen, R., Bucciarelli, S., Mehta, V., Sellés Baiget, Selene, Solbak, Sara Marie Øie, Bach, Anders, Mesa, Pablo, Hernandez, P. A., Montoya, Guillermo, Nguyen, T. T. T. N., Rand, Kasper Dyrberg, Boesen, T. & Gajhede, Michael, 2019, In: Scientific Reports. 9, 13 p., 4019.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    PNGase H+ variant from Rudaea cellulosilytica with improved deglycosylation efficiency for rapid analysis of eukaryotic N‐glycans and HDX‐MS analysis of glycoproteins.

    Guo, R., Zhang, T., Lambert, Thomas Ole Tandrup, Wang, T., Voglmeir, J., Rand, Kasper Dyrberg & Liu, L., 2022, In: Rapid Communications in Mass Spectrometry. 36, 21, 9 p., e9376.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 34783804