Kasper Dyrberg Rand

Kasper Dyrberg Rand

Professor


  1. 2019
  2. Published

    Investigating the Conformational Response of the Sortilin Receptor upon Binding Endogenous Peptide- and Protein Ligands by HDX-MS

    Trabjerg, Esben, Abu-Asad, N., Wan, Z., Kartberg, F., Christensen, S. & Rand, Kasper Dyrberg, 2 Jul 2019, In: Structure. 27, 7, p. 1103-1113.e3

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Recommendations for performing, interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments

    Masson, G. R., Burke, J. E., Ahn, N. G., Anand, G. S., Borchers, C., Brier, S., Bou-Assaf, G. M., Engen, J. R., Englander, S. W., Faber, J., Garlish, R., Griffin, P. R., Gross, M. L., Guttman, M., Hamuro, Y., Heck, A. J. R., Houde, D., Iacob, R. E., Jorgensen, T. J. D., Kaltashov, I. A. & 20 others, Klinman, J. P., Konermann, L., Man, P., Mayne, L., Pascal, B. D., Reichmann, D., Skehel, M., Snijder, J., Strutzenberg, T. S., Underbakke, E. S., Wagner, C., Wales, T. E., Walters, B. T., Weis, D. D., Wilson, D. J., Wintrode, P. L., Zhang, Z., Zheng, J., Schriemer, D. C. & Rand, Kasper Dyrberg, Jul 2019, In: Nature Methods. 16, 7, p. 595-602

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Hydrogen-Deuterium Exchange Mass Spectrometry (HDX-MS) Centroid Data Measured between 3.6 degrees C and 25.4 degrees C for the Fab Fragment of NISTmAb

    Hudgens, J. W., Gallagher, E. S., Karageorgos, I., Anderson, K. W., Huang, R. Y-C., Chen, G., Bou-Assaf, G. M., Espada, A., Chalmers, M. J., Harguindey, E., Zhang, H-M., Walters, B. T., Zhang, J., Venable, J., Steckler, C., Park, I., Brock, A., Lu, X., Pandey, R., Chandramohan, A. & 16 others, Anand, G. S., Nirudodhi, S. N., Sperry, J. B., Rouse, J. C., Carroll, J. A., Rand, Kasper Dyrberg, Leurs, U., Weis, D. D., Al-Naqshabandi, M. A., Hageman, T. S., Deredge, D., Wintrode, P. L., Papanastasiou, M., Lambris, J. D., Li, S. & Urata, S., 2 May 2019, In: Journal of Research of the National Institute of Standards and Technology. 124, 7 p., 124009.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    The First Community-Wide, Comparative Cross-linking Mass Spectrometry Study

    Iacobucci, C., Piotrowski, C., Aebersold, R., Amaral, B. C., Andrews, P. C., Bernfur, K., Borchers, C. H., Brodie, N. I., Bruce, J. E., Cao, Y., Chaignepain, S., Chavez, J. D., Claverol, S., Cox, J., Davis, T. N., Degliesposti, G., Dong, M-Q., Edinger, N., Emanuelsson, C., Gay, M. & 53 others, Gomes-Neto, F., Gozzo, F. C., Gutierrez, C. B., Haupt, C., Heck, A. J. R., Herzog, F., Huang, L., Hoopmann, M. R., Kalisman, N., Klykov, O., Kukačka, Z., Liu, F., MacCoss, M. J., Mechtler, K., Mesika, R., Moritz, R. L., Nagaraj, N., Nesati, V., Neves-Fereira, A. G. C., Ninnis, R., Novák, P., O'Reilly, F. J., Pelzing, M., Petrotchenko, E. V., Piersimoni, L., Plasencia, M., Pukala, T. L., Rand, Kasper Dyrberg, Rappsilber, J., Reichman, D., Sailer, C., Sarnowski, C. P., Scheltema, R. A., Schmidt, C., Schriemer, D. C., Shi, Y., Skehel, J. M., Slavin, M., Sobott, F., Solis-Mezarino, V., Stephanowitz, H., Stengel, F., Stieger, C. E., Trabjerg, Esben, Trnka, M. J., Vilaseca, M., Viner, R., Xiang, Y., Yılmaz, Ş., Zelter, A., Ziemianowicz, D. S., Leitner, A. & Sinz, A., 2 May 2019, In: Analytical Chemistry. 91, 11, p. 6953-6961

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published
  7. Published

    Conformational dynamics of the human serotonin transporter during substrate and drug binding

    Möller, I. R., Slivacka, M., Nielsen, A. K., Rasmussen, Søren Gøgsig Faarup, Gether, Ulrik, Loland, Claus Juul & Rand, Kasper Dyrberg, 11 Apr 2019, In: Nature Communications. 10, 1, 1687.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    A post-translational modification of human Norovirus capsid protein attenuates glycan binding

    Mallagaray, A., Creutznacher, R., Dülfer, J., Mayer, P. H. O., Grimm, L. L., Orduña, J. M., Trabjerg, Esben, Stehle, T., Rand, Kasper Dyrberg, Blaum, B. S., Uetrecht, C. & Peters, T., 21 Mar 2019, In: Nature Communications. 10, 1, 14 p., 1320.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Probing the Dissociation of Protein Complexes by Means of Gas-Phase H/D Exchange Mass Spectrometry

    Mistarz, U. H., Chandler, S. A., Brown, J. M., Benesch, J. L. P. & Rand, Kasper Dyrberg, 15 Jan 2019, In: Journal of the American Society for Mass Spectrometry. 30, 1, p. 45-57 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Thiol-ene microfluidic chip for performing hydrogen/deuterium exchange of proteins at sub-second timescales

    Svejdal, R. R., Dickinson, E. R., Sticker, Drago, Kutter, Jörg P. & Rand, Kasper Dyrberg, 15 Jan 2019, In: Analytical Chemistry. 91, 2, p. 1309-1317

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Improving the Sequence Coverage of Integral Membrane Proteins during Hydrogen/Deuterium Exchange Mass Spectrometry Experiments

    Möller, I. R., Slivacka, M., Hausner, J., Nielsen, A. K., Pospisilova, E., Rand, Kasper Dyrberg, Liskova, R., Polak, M., Loland, Claus Juul, Kadek, A., Man, P. & Rand, Kasper Dyrberg, 2019, In: Analytical Chemistry. 91, 17, p. 10970-10978 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Interlaboratory Comparison of Hydrogen-Deuterium Exchange Mass Spectrometry Measurements of the Fab fragment of NISTmAb

    Hudgens, J. W., Gallagher, E. S., Karageorgos, I., Anderson, K. W., Filliben, J. J., Huang, R. Y-C., Chen, G., Bou-Assaf, G. M., Espada, A., Chalmers, M. J., Harguindey, E., Zhang, H-M., Walters, B. T., Zhang, J., Venable, J. D., Steckler, C., Park, I., Brock, A., Lu, X., Pandey, R. K. & 17 others, Chandramohan, A., Anand, G. S., Nirudodhi, S. N., Sperry, J. B., Rouse, J. C., Carroll, J. A., Rand, Kasper Dyrberg, Leurs, U., Weis, D. D., Al-Naqshabandi, M. A., Hageman, T. S., Deredge, D., Wintrode, P. L., Papanastasiou, M., Lambris, J. D., Li, S. & Urata, S., 2019, In: Analytical Chemistry. 91, 11, p. 7336-7345

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Molecular architecture of the Jumonji C family histone demethylase KDM5B

    Dorosz, J., Kristensen, L. H., Aduri, N. G., Mirza, Osman Asghar, Lousen, R., Bucciarelli, S., Mehta, V., Sellés Baiget, Selene, Solbak, Sara Marie Øie, Bach, Anders, Mesa, Pablo, Hernandez, P. A., Montoya, Guillermo, Nguyen, T. T. T. N., Rand, Kasper Dyrberg, Boesen, T. & Gajhede, Michael, 2019, In: Scientific Reports. 9, 13 p., 4019.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Structure and Dynamics of a Promiscuous Xanthan Lyase from Paenibacillus nanensis and the Design of Variants with Increased Stability and Activity

    Jensen, P. F., Kadziola, Anders, Comamala, G., Segura, D. R., Anderson, L., Poulsen, Jens-Christian Navarro, Rasmussen, K. K., Agarwal, S., Sainathan, R. K., Monrad, R. N., Svendsen, A., Nielsen, J. E., Lo Leggio, Leila & Rand, Kasper Dyrberg, 2019, In: Cell Chemical Biology. 26, 2, p. 191-202.e1-e6 19 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Substrate-Induced Conformational Dynamics of the Dopamine Transporter

    Nielsen, A. K., Moller, I. R., Rasmussen, Søren Gøgsig Faarup, Rand, Kasper Dyrberg & Loland, Claus Juul, 2019, In: Biophysical Society. Annual Meeting. Abstracts. 116, 3, p. 346A 1 p., 1714-Pos.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  16. Published

    Substrate-induced conformational dynamics of the dopamine transporter

    Nielsen, A. K., Möller, I. R., Wang, Y., Rasmussen, Søren Gøgsig Faarup, Lindorff-Larsen, Kresten, Rand, Kasper Dyrberg & Loland, Claus Juul, 2019, In: Nature Communications. 10, 14 p., 2714.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. 2018
  18. Published

    Investigating the utility of minimized sample preparation and high-resolution mass spectrometry for quantification of monoclonal antibody drugs

    Nguyen, T. T. T. N., Mistarz, U. H., Costa, N., Herbet, A., Boquet, D., Becher, F. & Rand, Kasper Dyrberg, 10 Sep 2018, In: Journal of Pharmaceutical and Biomedical Analysis. 159, p. 384-392

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Conformational analysis of complex protein states by hydrogen/deuterium exchange mass spectrometry (HDX-MS): Challenges and emerging solutions

    Trabjerg, Esben, Nazari, Z. E. & Rand, Kasper Dyrberg, Sep 2018, In: Trends in Analytical Chemistry. 106, p. 125-138

    Research output: Contribution to journalReviewResearchpeer-review

  20. Published

    Side-chain moieties from the N-terminal region of Aβ are Involved in an oligomer-stabilizing network of interactions

    Przygońska, K., Poznański, J., Mistarz, U. H., Rand, Kasper Dyrberg & Dadlez, M., 6 Aug 2018, In: PLoS One. 13, 8, p. 1-25 25 p., e0201761.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Installation, validation, and application examples of two instrumental setups for gas-phase HDX-MS analysis of peptides and proteins

    Mistarz, U. H. & Rand, Kasper Dyrberg, 15 Jul 2018, In: Methods. 144, p. 113-124

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Structural Dynamics and Catalytic Properties of a Multimodular Xanthanase

    Moroz, O. V., Jensen, P. F., Mcdonald, S. P., Mcgregor, N., Blagova, E., Comamala, G., Segura, D. R., Anderson, L., Vasu, S. M., Rao, V. P., Giger, L., Sørensen, T. H., Monrad, R. N., Svendsen, A., Nielsen, J. E., Henrissat, B., Davies, G. J., Brumer, H., Rand, Kasper Dyrberg & Wilson, K. S., 6 Jul 2018, In: ACS Catalysis. 8, 7, p. 6021-6034

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Unusual Self-Assembly of the Recombinant Chlamydia trachomatis Major Outer Membrane Protein-Based Fusion Antigen CTH522 Into Protein Nanoparticles

    Rose, F., Karlsen, K., Jensen, P. R., Jakobsen, R. U., Wood, G. K., Rand, Kasper Dyrberg, Godiksen, H., Andersen, P., Follmann, F. & Foged, Camilla, Jun 2018, In: Journal of Pharmaceutical Sciences. 107, 6, p. 1690-1700 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Glycine Perturbs Local and Global Conformational Flexibility of a Transmembrane Helix

    Högel, P., Götz, A., Kuhne, F., Ebert, M., Stelzer, W., Rand, Kasper Dyrberg, Scharnagl, C. & Langosch, D., 27 Feb 2018, In: Biochemistry. 57, 8, p. 1326-1337 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Substrate-modulated unwinding of transmembrane helices in the NSS transporter LeuT: Recommended in F1000Prime as being of special significance in its field by F1000 Faculty Member Robert Vandenberg

    Merkle, P. S., Gotfryd, K., Cuendet, M. A., Leth-Espensen, K. Z., Gether, Ulrik, Loland, Claus Juul & Rand, Kasper Dyrberg, 2018, In: Science Advances. 4, 5, 12 p., eaar6179.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    UV Photodissociation Mass Spectrometry Accurately Localize Sites of Backbone Deuteration in Peptides

    Mistarz, U. H., Bellina, B., Jensen, P. F., Brown, J. M., Barran, P. E. & Rand, Kasper Dyrberg, 2018, In: Analytical Chemistry. 90, 2, p. 1077-1080 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. 2017
  28. Published

    A Poly-ADP-Ribose Trigger Releases the Auto-Inhibition of a Chromatin Remodeling Oncogene

    Singh, H. R., Nardozza, A. P., Möller, I. R., Knobloch, G., Kistemaker, H. A. V., Hassler, M., Harrer, N., Blessing, C., Eustermann, S., Kotthoff, C., Huet, S., Mueller-Planitz, F., Filippov, D. V., Timinszky, G., Rand, Kasper Dyrberg & Ladurner, A. G., 7 Dec 2017, In: Molecular Cell. 68, 5, p. 860-871.e7

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 34783804