Catharina Margrethe Lerche
Associate Professor
Toxicology and Drug Metabolism
Universitetsparken 2
2100 København Ø
- 2024
- Published
Ablative fractional laser treatment reduces hedgehog pathway gene expression in murine basal cell carcinomas
Pedersen, K. K., Granborg, J. R., Lerche, Catharina Margrethe, Litman, Thomas, Olesen, U. H. & Hædersdal, Merete, 2024, In: Lasers in Medical Science. 39, 1, 9 p., 55.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Anti-PD-1 immunotherapy with adjuvant ablative fractional laser displays increased tumour clearance of squamous cell carcinoma, a murine study
Christensen, R. L., Wiinberg, M., Lerche, Catharina Margrethe, Demehri, S., Olesen, U. H. & Hædersdal, Merete, 2024, In: Experimental Dermatology. 33, 2, 9 p., e15013.Research output: Contribution to journal › Journal article › Research › peer-review
- E-pub ahead of print
Efficacy of combinational treatment versus nicotinamide monotherapy in the prevention of ultraviolet radiation-induced skin cancer
Pihl, Celina, Andersen, F., Bjerring, P., Hædersdal, Merete & Lerche, Catharina Margrethe, 2024, (E-pub ahead of print) In: Dermatology. 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Oral administration of quercetin and fisetin potentiates photocarcinogenesis in UVR-exposed hairless mice
Pihl, Celina, Granborg, J. R., Pinto, F. E., Bjerring, P., Andersen, F., Janfelt, Christian, Hædersdal, Merete & Lerche, Catharina Margrethe, 2024, In: Phytomedicine Plus. 4, 2, 8 p., 100547.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Oral intake of bucillamine, carvedilol, metformin, or phenformin does not protect against UVR-induced squamous cell carcinomas in hairless mice
Pihl, Celina, Bjerring, P., Andersen, F., Hædersdal, Merete & Lerche, Catharina Margrethe, 2024, In: Photochemical and Photobiological Sciences. 23, p. 517-526Research output: Contribution to journal › Journal article › Research › peer-review
- Accepted/In press
Urinary thymidine dimer excretion reflects personal ultraviolet radiation exposure levels
Lerche, Catharina Margrethe, Frederiksen, N. J. S., Thorsteinsson, I. S., Køster, B., Nybo, Lars, Flouris, A. D., Heydenreich, J., Philipsen, P. A., Hædersdal, Merete, Wulf, H. C. & Granborg, J. R., 2024, (Accepted/In press) In: Photochemical and Photobiological Sciences.Research output: Contribution to journal › Journal article › Research › peer-review
- 2023
- Published
A randomized, placebo-controlled, trial to assess the photosensitizing, phototoxic and carcinogenic potential of hydrochlorothiazide in healthy volunteers
Götzinger, F., Hohl, M., Lauder, L., Millenaar, D., Kunz, M., Meyer, M. R., Ukena, C., Lerche, Catharina Margrethe, Philipsen, P. A., Reichrath, J., Böhm, M. & Mahfoud, F., 2023, In: Journal of Hypertension. 41, 11, p. 1853-1862Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparison of global DNA methylation analysis by whole genome bisulfite sequencing and the Infinium Mouse Methylation BeadChip using fresh and fresh-frozen mouse epidermis
Meyer, Olivia Luxford, Andersen, M. M., Børsting, Claus, Morling, Niels, Wulf, H. C., Philipsen, P. A., Lerche, Catharina Margrethe & Andersen, Jeppe Dyrberg, 2023, In: Epigenetics. 18, 1, 10 p., 2144574 .Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Does systemic hydrochlorothiazide increase the risk of developing ultraviolet radiation-induced skin tumours in hairless mice?
Lerche, Catharina Margrethe, Al-Chaer, R. N. & Wulf, H. C., 2023, In: Experimental Dermatology. 32, 4, p. 341-347Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Experimental and approved treatments for skin photosensitivity in individuals with erythropoietic protoporphyria or X-linked protoporphyria: A systematic review
Heerfordt, I. M., Lerche, Catharina Margrethe, Philipsen, P. A. & Wulf, H. C., 2023, In: Biomedicine and Pharmacotherapy. 158, 11 p., 114132.Research output: Contribution to journal › Review › Research › peer-review
- Published
Improving the efficacy of photodynamic therapy for actinic keratosis: A comprehensive review of pharmacological pretreatment strategies
Pihl, Celina, Lerche, Catharina Margrethe, Andersen, F., Bjerring, P. & Hædersdal, Merete, 2023, In: Photodiagnosis and Photodynamic Therapy. 43, 8 p., 103703.Research output: Contribution to journal › Review › Research › peer-review
- Published
Oral phytochemicals as photoprotectants in UVR exposed hairless mice: A study of hesperidin methyl chalcone, phloroglucinol, and syringic acid
Pihl, Celina, Bendtsen, K. M. S., Jensen, Henrik Elvang, Andersen, F., Bjerring, P., Hædersdal, Merete & Lerche, Catharina Margrethe, 2023, In: Journal of Photochemistry and Photobiology B: Biology. 246, 112760.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Phototesting in erythropoietic protoporphyria trials: A systematic review
Heerfordt, I. M., Philipsen, P. A., Lerche, Catharina Margrethe & Wulf, H. C., 2023, In: Experimental Dermatology. 32, 7, p. 1042-1047Research output: Contribution to journal › Review › Research › peer-review
- Published
Protection against visible light by dihydroxyacetone in erythropoietic protoporphyria
Heerfordt, I. M., Philipsen, P. A., Lerche, Catharina Margrethe & Wulf, H. C., 2023, In: Photodiagnosis and Photodynamic Therapy. 41, 5 p., 103302.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Repeated exposure to fractional CO2 laser delays squamous cell carcinoma formation and prevents clinical and subclinical photodamage visualized by line-field confocal optical coherence tomography and histology
Olesen, U. H., Jacobsen, K., Lerche, Catharina Margrethe & Hædersdal, Merete, 2023, In: Lasers in Surgery and Medicine. 55, 1, 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2022
- Published
A one-time pneumatic jet-injection of 5-fluorouracil and triamcinolone acetonide for treatment of hypertrophic scars: A blinded randomized controlled trial
Erlendsson, A. M., Rosenberg, L. K., Lerche, Catharina Margrethe, Togsverd-Bo, K., Wiegell, Stine Regin, Karmisholt, Katrine Elisabeth, Philipsen, P. A., Hansen, Anders Christian Nørgaard, Janfelt, Christian, Holmes, J., Rossi, A. & Hædersdal, Merete, 2022, In: Lasers in Surgery and Medicine. 54, 5, p. 663-671Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cimetidine for erythropoietic protoporphyria
Heerfordt, I. M., Lerche, Catharina Margrethe & Wulf, H. C., 2022, In: Photodiagnosis and Photodynamic Therapy. 38, 5 p., 102793.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Detection of cutaneous malignant melanoma using RNA sampled by tape strips: A study protocol
Heerfordt, I. M., Andersen, Jeppe Dyrberg, Philipsen, P. A., Langhans, L., Tvedebrink, Torben, Schmidt, G., Poulsen, T., Lerche, Catharina Margrethe, Morling, Niels & Wulf, H. C., 2022, In: PLoS ONE. 17, 9 , 11 p., e0274413.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Distribution of protoporphyrin IX in erythrocytes in a case of acquired erythropoietic protoporphyria
Heerfordt, I. M., Fontenete, S., Lerche, Catharina Margrethe & Wulf, H. C., 2022, In: Photodiagnosis and Photodynamic Therapy. 37, 3 p., 102629.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High Oral Vitamin D3 Intake Does Not Protect Against UVR-induced Squamous Cell Carcinoma in Mice
Lerche, Catharina Margrethe, Pinto, F. E., Philipsen, P. A., Bech, E. S., Jakobsen, J., Hædersdal, Merete & Wulf, H. C., 2022, In: Anticancer Research. 42, 10, p. 5083-5090Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High oral vitamin D intake does not protect against UVR-induced squamous cell carcinoma in hairless mice
Lerche, Catharina Margrethe, Pinto, F. E., Philipsen, P. A., Bech, E., Jakobsen, J., Hædersdal, Merete & Wulf, H. C., 2022, In: Anticancer Research. 42, 4, p. 2205-2205Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
In vivo dermal delivery of bleomycin with electronic pneumatic injection: drug visualization and quantification with mass spectrometry
Bik, L., van Doorn, M., Hansen, Anders Christian Nørgaard, Janfelt, Christian, Olesen, U. H., Hædersdal, Merete, Lerche, Catharina Margrethe & Hendel, K., 2022, In: Expert Opinion on Drug Delivery. 19, 2, p. 213-219Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nicotinamide and phytochemicals phloroglucinol and syringic acid delay uvr-induced squamous cell carcinoma onset in hairless mice
Pihl, Celina, Andersen, F., Bjerring, P., Hædersdal, Merete & Lerche, Catharina Margrethe, 2022, In: Anticancer Research. 42, 4, p. 2207-2207Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Quantification of Urinary Thymidine Dimers in Volunteers After Ultraviolet Radiation Using a New UPLC-MS/MS-based Method
Lerche, Catharina Margrethe, Philipsen, P. A., Hermansson, S., Heydenreich, J. & Wulf, H. C., 2022, In: Anticancer Research. 42, 10, p. 5069-5076Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quantifying urinary thymine dimers based on LC-MS/MS
Lerche, Catharina Margrethe, Philipsen, P. A., Hermansson, S., Heydenreich, J. & Wulf, H. C., 2022, In: Anticancer Research. 42, 4, p. 2204-2204 22.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Quantitative Mass Spectrometry Imaging of Bleomycin in Skin Using a Mimetic Tissue Model for Calibration
Traberg, A., Pinto, F. E., Hansen, Anders Christian Nørgaard, Hædersdal, Merete, Lerche, Catharina Margrethe & Janfelt, Christian, 2022, In: Pharmaceuticals. 15, 12, 15 p., 1583.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Topical Brimonidine Delays Ultraviolet Radiation-Induced Squamous Cell Carcinoma in Hairless Mice
Pinto, F. E., Olsen, P., Glud, M., Wulf, H. C. & Lerche, Catharina Margrethe, 2022, In: Photochemistry and Photobiology. 98, 6, p. 1390-1394Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
A Skin Cancer Prophylaxis Study in Hairless Mice Using Methylene Blue, Riboflavin, and Methyl Aminolevulinate as Photosensitizing Agents in Photodynamic Therapy
Wulf, H. C., Al-Chaer, R. N., Glud, M., Philipsen, P. A. & Lerche, Catharina Margrethe, May 2021, In: Pharmaceuticals. 14, 5, 11 p., 433.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bleomycin administered by laser-assisted drug delivery or intradermal needle-injection results in distinct biodistribution patterns in skin: in vivo investigations with mass spectrometry imaging
Hendel, K., Hansen, Anders Christian Nørgaard, Bik, L., Bagger, C., van Doorn, M. B. A., Janfelt, Christian, Olesen, U. H., Hædersdal, Merete & Lerche, Catharina Margrethe, 1 Jan 2021, In: Drug Delivery. 28, 1, p. 1141-1149 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Comparison of Human and Porcine Skin in Laser-Assisted Drug Delivery of Chemotherapeutics
Rosenberg, L. K., Bagger, C., Janfelt, Christian, Hædersdal, Merete, Olesen, U. H. & Lerche, Catharina Margrethe, 2021, In: Lasers in Surgery and Medicine. 53, 1, p. 162-170 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Anti-pd-1 therapy with adjuvant ablative fractional laser improves anti-tumor response in basal cell carcinomas
Olesen, U. H., Wiinberg, M., Lerche, Catharina Margrethe, Jæhger, D. E., Andresen, T. L. & Hædersdal, Merete, 2021, In: Cancers. 13, 24, 14 p., 6326.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Few X-ray and PUVA treatments accelerate photocarcinogenesis in hairless mice
Lerche, Catharina Margrethe, Al-Chaer, R. N., Glud, M., Philipsen, P. A. & Wulf, H. C., 2021, In: Photochemical and Photobiological Sciences. 20, 10, p. 1299-1307Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Keratinocyte Carcinoma and Photoprevention: The Protective Actions of Repurposed Pharmaceuticals, Phytochemicals and Vitamins
Pihl, Celina, Togsverd-Bo, K., Andersen, F., Hædersdal, Merete, Bjerring, P. & Lerche, Catharina Margrethe, 2021, In: Cancers. 13, 15, 29 p., 3684.Research output: Contribution to journal › Review › Research › peer-review
- Published
Tumor Clearance and Immune Cell Recruitment in UV-Induced Murine Squamous Cell Carcinoma Exposed to Ablative Fractional Laser and Imiquimod Treatment
Fontenete, S., Lerche, Catharina Margrethe, Paasch, U., Perez-Moreno, Mirna, Olesen, U. H. & Hædersdal, Merete, 2021, In: Lasers in Surgery and Medicine. 53, 9, p. 1227-1237 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2020
- Published
Enhanced and Sustained Cutaneous Delivery of Vismodegib by Ablative Fractional Laser and Microemulsion Formulation
Olesen, U. H., Clergeaud, G., Hendel, K. K., Yeung, Kelvin, Lerche, Catharina Margrethe, Andresen, T. L. & Hædersdal, Merete, 2020, In: Journal of Investigative Dermatology. 140, 10, p. 2051-2059 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 250642459
Most downloads
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46
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Keratinocyte Carcinoma and Photoprevention: The Protective Actions of Repurposed Pharmaceuticals, Phytochemicals and Vitamins
Research output: Contribution to journal › Review › Research › peer-review
Published -
37
downloads
Bleomycin administered by laser-assisted drug delivery or intradermal needle-injection results in distinct biodistribution patterns in skin: in vivo investigations with mass spectrometry imaging
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
30
downloads
A Skin Cancer Prophylaxis Study in Hairless Mice Using Methylene Blue, Riboflavin, and Methyl Aminolevulinate as Photosensitizing Agents in Photodynamic Therapy
Research output: Contribution to journal › Journal article › Research › peer-review
Published