Birger Brodin Larsen

Birger Brodin Larsen

Professor


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  1. Published

    IPEC-J2 rMdr1a, a New Cell Line with Functional Expression of Rat P-glycoprotein Encoded by Rat Mdr1a for Drug Screening Purposes

    Saaby, Lasse, Trasborg, J., Rasmussen, M. A., Holst, B. & Larsen, Birger Brodin, 17 Jul 2020, In: Pharmaceutics. 12, 7, 17 p., 673.

    Research output: Contribution to journal › Journal article › peer-review

  2. Published

    IPEC-J2 MDR1, a Novel High-Resistance Cell Line with Functional Expression of Human P-glycoprotein (ABCB1) for Drug Screening Studies

    Saaby, Lasse, Helms, H. C. C. & Larsen, Birger Brodin, 1 Feb 2016, In: Molecular Pharmaceutics. 13, 2, p. 640-52 13 p.

    Research output: Contribution to journal › Journal article › peer-review

  3. Published

    IN VITRO MEMBRANE PERMEATION STUDIES AND IN VIVO ANTINOCICEPTION OF GLYCOSYLATED Dmt1-DALDA ANALOGUES

    Betti, C., Novoa, A., Tömböly, C., Nielsen, C. U., Helms, H. C. C., Lesniak, A., Klecskowska, P., Chung, N. N., Chung, N. N., Lipkowski, A. W., Larsen, Birger Brodin, Tourwé, D., Schiller, P. W. & Ballet, S., 31 Aug 2014. 1 p.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  4. Published

    Hypoxia increases expression of selected blood–brain barrier transporters GLUT-1, P-gp, SLC7A5 and TFRC, while maintaining barrier integrity, in brain capillary endothelial monolayers

    Ozgür, Burak, Helms, H. C. C., Tornabene, E. & Larsen, Birger Brodin, 2022, In: Fluids and Barriers of the CNS. 19, 1, 17 p.

    Research output: Contribution to journal › Journal article › peer-review

  5. Published

    Human peptide transporters: Therapeutic applications

    Nielsen, C. U., Larsen, Birger Brodin, Jørgensen, Flemming Steen, Frøkjær, Sven & Steffansen, B., 1 Sep 2002, In: Expert Opinion on Therapeutic Patents. 12, 9, p. 1329-1350 22 p.

    Research output: Contribution to journal › Journal article › peer-review

  6. Published

    Human induced pluripotent stem cells (BIONi010-C) generate tight cell monolayers with blood-brain barrier traits and functional expression of large neutral amino acid transporter 1 (SLC7A5)

    Goldeman, C., Andersen, M., Al-Robai, A., Buchholtz, T., Svane, Nana Isabella, Ozgür, Burak, Holst, B., Shusta, E., Hall, Vanessa Jane, Saaby, Lasse, Hyttel, P. & Larsen, Birger Brodin, 2021, In: European Journal of Pharmaceutical Sciences. 156, 14 p., 105577.

    Research output: Contribution to journal › Journal article › peer-review

  7. Published

    Hjernens forsvarsmur kortlagt og kopieret

    Helms, H. C., Waagepetersen, Helle S., Nielsen, C. U. & Larsen, Birger Brodin, 2010, In: Lægemiddelforskning. 2010, p. 22-24

    Research output: Contribution to journal › Journal article

  8. Published

    Highly cationic cell-penetrating peptides affect the barrier integrity and facilitates mannitol permeation in a human stem cell-based blood-brain barrier model

    Frøslev, Patrick, Franzyk, Henrik, Ozgür, Burak, Larsen, Birger Brodin & Kristensen, Mie, 2022, In: European Journal of Pharmaceutical Sciences. 168, 10 p., 106054.

    Research output: Contribution to journal › Journal article › peer-review

  9. Published

    Gly-sar is a substrate for the human proton coupled amino acid trasporter 1, hPAT1 (SLC36A1)

    Frølund, S. B., Holm, R., Larsen, Birger Brodin & Nielsen, C. U., 2010.

    Research output: Contribution to conference › Poster › Research

  10. Published

    Gly-Sar is a substrate for the human proton-coupled amino acid transporter, hPAT1 (SLC36A1)

    Frølund, S. B., Holm, R., Larsen, Birger Brodin & Nielsen, C. U., Mar 2010.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  11. Published

    Glutamate efflux from brain to blood - Studies in an in vitro blood-brain barrier model

    Helms, H. C. C., Madelung, R., Waagepetersen, Helle S., Nielsen, C. U. & Larsen, Birger Brodin, 2012.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  12. Published

    Glutamate Transporters in the Blood-Brain Barrier

    Helms, H. C. C., Nielsen, C. U., Waagepetersen, Helle S. & Larsen, Birger Brodin, 2017, Glial Amino Acid Transporters. Vol. 16. p. 297-314 18 p. (Advances in Neurobiology).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  13. Published

    Glutamate Efflux at the Blood-Brain Barrier: Cellular Mechanisms and Potential Clinical Relevance

    Cederberg-Helms, H. C., Uhd-Nielsen, C. & Larsen, Birger Brodin, 15 Nov 2014, In: Archives of Medical Research. 45, 8, p. 639-645 7 p.

    Research output: Contribution to journal › Journal article › peer-review

  14. Published

    Genetic variants of the human dipeptide transporter PEPT1

    Anderle, P., Nielsen, C. U., Pinsonneault, J., Krog, P. L., Larsen, Birger Brodin & Sadée, W., 1 Feb 2006, In: Journal of Pharmacology and Experimental Therapeutics. 316, 2, p. 636-646 11 p.

    Research output: Contribution to journal › Journal article › peer-review

  15. Published

    Generation of primary cultures of bovine brain endothelial cells and setup of cocultures with rat astrocytes

    Helms, H. C. & Larsen, Birger Brodin, 2014, In: Methods in molecular biology (Clifton, N.J.). 1135, p. 365-82 18 p.

    Research output: Contribution to journal › Journal article › peer-review

  16. Published

    Generation of a rat in-vitro blood-brain barrier model and initial insights on excitatory amino acid transporter expression

    Groth, S., Moos, T., Helms, H. C. C. & Larsen, Birger Brodin, 2012. 1 p.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  17. Published

    Gaboxadol bliver absorberet via en aminosyretransportør

    Broberg, M. L., Holm, R., Jensen, K. G., Larsen, Birger Brodin & Nielsen, C. U., 2009, In: Lægemiddelforskning. p. 22-24

    Research output: Contribution to journal › Journal article

  18. Published

    GABA transport across the basolateral membrane of intestinal cells

    Nielsen, C. U., Carstensen, M. & Larsen, Birger Brodin, 2010. 1 p.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  19. Published

    Functional Insulin Receptor expression does not facilitate transendothelial passage of insulin in a bovine in vitro blood-brain barrier model

    Hersom, M. N. S., Helms, H. C. C., Pedersen, T., Buckley, S. & Larsen, Birger Brodin, 3 Mar 2016.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  20. Published

    Function and expression of the proton-coupled amino acid transporter Slc36a1 along the rat gastrointestinal tract: Implications for intestinal absorption of gaboxadol

    Broberg, M. L., Holm, R. K., Tønsberg, H., Frølund, S. B., Ewon, K. B., Nielsen, A. L., Larsen, Birger Brodin, Jensen, A., Kall, M. A., Nielsen, C. U. & Christensen, K. V., 2012, In: British Journal of Pharmacology. 167, 3, p. 654-665

    Research output: Contribution to journal › Journal article › peer-review

  21. Published

    Expression profiles of selected receptor systems in a bovine in vitro blood-brain barrier model

    Hersom, M. N. S., Helms, H. C. C., Nielsen, M. S., Holm, R. & Larsen, Birger Brodin, 10 Dec 2014. 1 p.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  22. Published

    Expression and functional activity of the efflux transporters BCRP and P-gp in bovine endothelial cells, co-cultured with rat astrocytes

    Hersom, M. N. S., Helms, H. C. C., Kuhlmann, L. B., Badolo, L. & Larsen, Birger Brodin, 2013. 1 p.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  23. Published

    Excitatory amino acid transporter-1 (EAAT1) is the main transporter responsible for abluminal uptake of L-glutamate in bovine brain endothelial cells

    Helms, H. C. C., Groth, S., Mikél, M., Waagepetersen, Helle S., Nielsen, C. U. & Larsen, Birger Brodin, 27 May 2013.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  24. Published

    Evidence for a Na+/Ca2+ exchange mechanism in frog skin epithelium

    Madsen, K. H., Larsen, Birger Brodin & Nielsen, Rasmus, 1999, In: Pflügers Archiv - European Journal of Physiology. 437, 2, p. 175-81 7 p.

    Research output: Contribution to journal › Journal article › peer-review

  25. Published

    Evidence for P2Y-type ATP receptors on the serosal membrane of frog skin epithelium

    Larsen, Birger Brodin & Nielsen, R., 1 Jan 2000, In: Pflugers Archiv European Journal of Physiology. 439, 3, p. 234-239 6 p.

    Research output: Contribution to journal › Journal article › peer-review

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